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1.
Rev. esp. cir. ortop. traumatol. (Ed. impr.) ; 68(1): 18-25, Ene-Feb, 2024. tab, graf
Article in Spanish | IBECS | ID: ibc-229665

ABSTRACT

Introducción: El proceso diagnóstico de los sarcomas de partes blandas del aparato locomotor (SPBAL) sigue siendo comprometido, con casos de resecciones no planificadas (cirugías «whoops»). Este estudio evalúa la frecuencia de este tipo de procedimientos, tratando de identificar características de los pacientes, tumores, tratamiento quirúrgico y resultados. Material y métodos: Se revisan de forma retrospectiva 131 pacientes tratados de forma quirúrgica en nuestro centro entre octubre de 2018 y diciembre de 2021 de un SPBAL. Se excluyen los pacientes con SPBAL localizados en vísceras, mediastino, corazón, retroperitoneo, peritoneo y aparato genital. Las diferencias entre pacientes con resecciones planificadas y no planificadas fueron evaluadas con pruebas χ2 y un modelo de regresión multivariado de Cox. Resultados: Las resecciones no planificadas de SPBAL han tenido lugar en 18% de los pacientes de nuestra área, principalmente en tumores menos de 5 cm y localizados superficiales a la fascia; 29,2% de estos pacientes no disponían de una prueba de imagen previa. No se ha demostrado que una cirugía «whoops» pueda suponer una disminución de la supervivencia o una mayor tasa de recidivas. Conclusiones: Recomendamos la realización de una prueba de imagen siempre previa a la extirpación de cualquier tipo de tumoración de tejidos blandos, así como la adherencia a las guías de remisión a centros de referencia.(AU)


Introduction: The diagnosis process of soft tissue sarcomas of the musculoskeletal system (SPBAL) continues to be complex, with cases of unplanned excisions (“whoops” surgeries). This study evaluates the frequency of these type of procedures, trying to indentify patient characteristics, tumors, surgical treatment and final results. Material and methods: 131 patients treated surgically between October 2018 and December 2021 of a SPBAL were retrospectively reviewed. Patients with SPBAL located in the viscera, mediastinum, heart, retroperitoneum, peritoneum and genital tract were excluded. Differences between patients with planned and unplanned excisions were assessed with chi2 tests and a Cox multivariate regression model. Results: Unplanned excisions of SPBAL have taken place in 18% of the patients in our área, mainly in tumors of less than 5 cm and located superficial to the fascia. 29,2% of these patients did not have a previous imaging test. It has not been shown that a “whoops” surgery can lead to a decrease in survival or a higher rate of recurrences. Conclusions: We recommend carrying out an imaging test always prior to the removal of any type of soft tissue tumor, as well as adherence to the referral guidelines to reference centers.(AU)


Subject(s)
Humans , Male , Female , Sarcoma, Clear Cell/surgery , Neoplasms/surgery , Motor Activity , Sarcoma/drug therapy
2.
Rev. esp. cir. ortop. traumatol. (Ed. impr.) ; 68(1): T18-T25, Ene-Feb, 2024. tab, graf
Article in English | IBECS | ID: ibc-229666

ABSTRACT

Introducción: El proceso diagnóstico de los sarcomas de partes blandas del aparato locomotor (SPBAL) sigue siendo comprometido, con casos de resecciones no planificadas (cirugías «whoops»). Este estudio evalúa la frecuencia de este tipo de procedimientos, tratando de identificar características de los pacientes, tumores, tratamiento quirúrgico y resultados. Material y métodos: Se revisan de forma retrospectiva 131 pacientes tratados de forma quirúrgica en nuestro centro entre octubre de 2018 y diciembre de 2021 de un SPBAL. Se excluyen los pacientes con SPBAL localizados en vísceras, mediastino, corazón, retroperitoneo, peritoneo y aparato genital. Las diferencias entre pacientes con resecciones planificadas y no planificadas fueron evaluadas con pruebas χ2 y un modelo de regresión multivariado de Cox. Resultados: Las resecciones no planificadas de SPBAL han tenido lugar en 18% de los pacientes de nuestra área, principalmente en tumores menos de 5 cm y localizados superficiales a la fascia; 29,2% de estos pacientes no disponían de una prueba de imagen previa. No se ha demostrado que una cirugía «whoops» pueda suponer una disminución de la supervivencia o una mayor tasa de recidivas. Conclusiones: Recomendamos la realización de una prueba de imagen siempre previa a la extirpación de cualquier tipo de tumoración de tejidos blandos, así como la adherencia a las guías de remisión a centros de referencia.(AU)


Introduction: The diagnosis process of soft tissue sarcomas of the musculoskeletal system (SPBAL) continues to be complex, with cases of unplanned excisions (“whoops” surgeries). This study evaluates the frequency of these type of procedures, trying to indentify patient characteristics, tumors, surgical treatment and final results. Material and methods: 131 patients treated surgically between October 2018 and December 2021 of a SPBAL were retrospectively reviewed. Patients with SPBAL located in the viscera, mediastinum, heart, retroperitoneum, peritoneum and genital tract were excluded. Differences between patients with planned and unplanned excisions were assessed with chi2 tests and a Cox multivariate regression model. Results: Unplanned excisions of SPBAL have taken place in 18% of the patients in our área, mainly in tumors of less than 5 cm and located superficial to the fascia. 29,2% of these patients did not have a previous imaging test. It has not been shown that a “whoops” surgery can lead to a decrease in survival or a higher rate of recurrences. Conclusions: We recommend carrying out an imaging test always prior to the removal of any type of soft tissue tumor, as well as adherence to the referral guidelines to reference centers.(AU)


Subject(s)
Humans , Male , Female , Sarcoma, Clear Cell/surgery , Neoplasms/surgery , Motor Activity , Sarcoma/drug therapy
3.
Rev Esp Cir Ortop Traumatol ; 68(1): 18-25, 2024.
Article in English, Spanish | MEDLINE | ID: mdl-36841328

ABSTRACT

INTRODUCTION: The diagnosis process of soft tissue sarcomas of the musculoskeletal system (SPBAL) continues to be complex, with cases of unplanned excisions ("whoops" surgeries). This study evaluates the frequency of these type of procedures, trying to indentify patient characteristics, tumors, surgical treatment and final results. MATERIAL AND METHODS: 131 patients treated surgically between October 2018 and December 2021 of a SPBAL were retrospectively reviewed. Patients with SPBAL located in the viscera, mediastinum, heart, retroperitoneum, peritoneum and genital tract were excluded. Differences between patients with planned and unplanned excisions were assessed with chi2 tests and a Cox multivariate regression model. RESULTS: Unplanned excisions of SPBAL have taken place in 18% of the patients in our área, mainly in tumors of less than 5 cm and located superficial to the fascia. 29,2% of these patients did not have a previous imaging test. It has not been shown that a "whoops" surgery can lead to a decrease in survival or a higher rate of recurrences. CONCLUSIONS: We recommend carrying out an imaging test always prior to the removal of any type of soft tissue tumor, as well as adherence to the referral guidelines to reference centers.

4.
Rev Esp Cir Ortop Traumatol ; 68(1): T18-T25, 2024.
Article in English, Spanish | MEDLINE | ID: mdl-37981200

ABSTRACT

INTRODUCTION: The diagnosis process of soft tissue sarcomas of the musculoskeletal system (SPBAL) continues to be complex, with cases of unplanned excisions ("whoops" surgeries). This study evaluates the frequency of these type of procedures, trying to identify patient characteristics, tumours, surgical treatment and final results. MATERIAL AND METHODS: 131 patients treated surgically between October 2018 and December 2021 of a SPBAL were retrospectively reviewed. Patients with SPBAL located in the viscera, mediastinum, heart, retroperitoneum, peritoneum and genital tract were excluded. Differences between patients with planned and unplanned excisions were assessed with Chi2 tests and a Cox multivariate regression model. RESULTS: Unplanned excisions of SPBAL have taken place in 18% of the patients in our area, mainly in tumours of less than 5cm and located superficial to the fascia. 29.2% of these patients did not have a previous imaging test. It has not been shown that a "whoops" surgery can lead to a decrease in survival or a higher rate of recurrences. CONCLUSIONS: We recommend carrying out an imaging test always prior to the removal of any type of soft tissue tumour, as well as adherence to the referral guidelines to reference centres.

5.
Medisan ; 26(3)jun. 2022. ilus
Article in Spanish | LILACS, CUMED | ID: biblio-1405811

ABSTRACT

Se describe el caso clínico de un paciente de 61 años de edad, con antecedente de buena salud, atendido en el St. Paul's Milennium Medical Hospital de Etiopía por presentar, desde hacía 2 años, una lesión en la encía marginal, con abombamiento de ambas corticales, que se extendía del primer premolar inferior derecho al izquierdo, por lo cual se decidió ingresarlo en el Servicio de Cirugía Maxilofacial para su estudio y tratamiento. Se trataba de un tumor poco frecuente y de gran tamaño, con amplia diseminación ganglionar hacia los niveles IV y V de ambas partes del cuello, de manera que se realizó el procedimiento quirúrgico. La evolución fue favorable en el posoperatorio inmediato y egresó de la institución 7 días después, pero continuó con radioterapia. Y seguimiento por consulta externa durante 24 meses después.


The clinical case of a 61-year-old patient, with a history of good health, treated at St. Paul's Milennium Medical Hospital in Ethiopia for presenting, for 2 years, a lesion in the marginal gum, with bulging of the gums, is described. both cortices, which extended from the lower right to the left first premolar, for which it was decided to admit him to the Maxillofacial Surgery Service for study and treatment. It was a rare and large tumor, with extensive lymph node dissemination to levels IV and V in both parts of the neck, so the surgical procedure was performed. The evolution was favorable in the immediate postoperative period and he was discharged from the institution 7 days later, but continued with radiotherapy. And follow-up by outpatient service for 24 months afterwards.


Subject(s)
Histiocytoma, Malignant Fibrous , Myxosarcoma
6.
Medisan ; 26(1)feb. 2022. ilus
Article in Spanish | LILACS, CUMED | ID: biblio-1405777

ABSTRACT

Los sarcomas de partes blandas son tumores malignos que se originan en el tejido conectivo, a partir del mesénquima embrionario. Teniendo en cuenta la existencia de nuevos y constantes cambios en la naturaleza de estos tumores, se realizó una revisión de las publicaciones más recientes para profundizar en las alteraciones genéticas, los síndromes de predisposición y su relación con los sarcomas. Se pudo concluir que aún siguen siendo muy pocos los registros que describen la identificación de dichos síndromes como principal eslabón en el desarrollo de los sarcomas.


The sarcomas of soft parts are malignancies that originate in the connective tissue, starting from the embryonic mesenchyme. Taking into account the existence of new and constant changes in the nature of these tumors, a review of the most recent publications was carried out to deepen in the genetic disorders, the predisposing syndromes and its relationship with sarcomas. It was concluded that the records that describe the identification of these syndromes are still very few as main link in the development of sarcomas.


Subject(s)
Sarcoma , Genetic Diseases, Inborn , Sarcoma, Clear Cell , Genetic Predisposition to Disease
7.
Rev. cuba. med ; 59(2): e803, abr.-jun. 2020.
Article in Spanish | LILACS, CUMED | ID: biblio-1139051

ABSTRACT

Introducción: El sarcoma de tejidos blandos (STB) constituye un grupo variado de más de 60 neoplasias que solo suponen 1 por ciento del total de los tumores. Objetivo: Describir el caso de un paciente con sarcoma de partes blandas con metástasis ósea y manifestaciones paraneoplásicas. Caso clínico: Se presenta el caso de un paciente masculino de 55 años de edad con antecedentes de diabetes mellitus tipo 2 e hipertensión arterial que refiere que hace 50 días inició con decaimiento marcado, luego de permanecer 1 mes con este síntoma inició con dolor en la columna en la parte más baja de la espalda, conjuntamente iniciando con un cuadro febril. Además, tuvo pérdida de la fuerza principalmente en las piernas, y hablaba cosas incoherentes sin sentido, gran inapetencia, con pérdida de peso de 50 lb en 20 días. Ante cuadro de pérdida de la conciencia y de la fuerza principalmente en las piernas se decidió su remisión hacia el Hospital Clínico Quirúrgico Lucía Íñiguez Landín de Holguín donde se concluyó como sarcoma de partes blandas con manifestaciones paraneoplásicas y metástasis ósea. Conclusiones: El caso presentado de sarcoma de partes blandas pretende aportar información sobre esta enfermedad tan infrecuente en nuestro medio(AU)


Introduction: Soft tissue sarcoma (STB) constitutes a varied group of more than 60 malignancies that only accounts for 1% of all tumors. Objective: To report a case of a patient with soft tissue sarcoma with bone metastases and paraneoplastic manifestations. Clinical case report: We report the case of a 55-year-old male patient with a history of type 2 diabetes mellitus and hypertension, who stated that 50 days ago he began to feel markedly listless. And after a month he began to suffer pain in the spine, in the lower back, and have a fever. In addition he had loss of strength mainly in the legs, and spoke inconsistently, nonsense, great loss of appetite, with weight loss of 50 lbs in 20 days. Given the condition of loss of consciousness and strength, mainly in the legs, it was decided to refer him to Lucía Iñiguez Landín Surgical Clinical Hospital in Holguín, where a soft tissue sarcoma with paraneoplastic manifestations and bone metastases was diagnosed. Conclusions: The report of this case of soft tissue sarcoma aims to provide information about this disease, which is so rare in our setting(AU)


Subject(s)
Humans , Male , Paraneoplastic Syndromes , Biopsy/methods , Sarcoma, Alveolar Soft Part/complications , Neoplasms, Bone Tissue/secondary , Leiomyosarcoma/diagnostic imaging
8.
An. Fac. Cienc. Méd. (Asunción) ; 53(1): 101-106, 20200401.
Article in Spanish | LILACS | ID: biblio-1095728

ABSTRACT

Los tumores de partes blandas son tumores que se presentan en adultos, aproximadamente a los 60 años. De estos tumores los sarcomas son poco frecuentes y tienen preferencia en las extremidades y muchas veces invaden estructuras músculo aponeuróticas cercanas, y poca invasión vascular o nerviosa lo que las hace de fácil acceso con poca morbilidad para su biopsia. El diagnóstico de los tumores de partes blandas se basa en el estudio histológico de anatomía patológica y, a veces se debe asociar a estudios de citogenética para poder tener un diagnóstico específico. El tratamiento principal es quirúrgico y puede llegar estar asociado a terapia adyuvante.


Soft tissue tumors are tumors that occur in adult's age, at about 60 age. Of these tumors, sarcomas are rare and have preference in the extremities, and often invade nearby muscle-fascia structures, and little vascular or nerve invasion, making them easily accessible with little morbidity for biopsy. The diagnosis of soft tissue tumors is based on the histological study of pathological anatomy and, sometimes, it must be associated with cytogenetic studies in order to have specific diagnosis. The main treatment is surgical and may end up being associated with adjuvant therapy.


Subject(s)
Sarcoma, Clear Cell , Women
9.
Cir Esp (Engl Ed) ; 98(5): 281-287, 2020 May.
Article in English, Spanish | MEDLINE | ID: mdl-31806234

ABSTRACT

INTRODUCTION: Up to 40% of all initial operations for soft tissue sarcoma (STS) are unplanned, which would leave residual macroscopic tumor in more than 50% of the cases. The effect this has on local recurrence rate, metastases rate and survival has never been fully established, due to the lack of randomized studies. METHODS: Retrospective review of patients with STS treated in our unit between January 2001-January 2016. We classified them whether they had been treated by initial planned or unplanned operation. Outcomes were compared in both groups globally and stage-matched. Endpoints were local recurrence and distant metastases. RESULTS: Twenty-three patients of STS underwent a planned excision and 16 an unplanned excision, 13 of them underwent further re-excision. 40% of patients with planned excision had an advanced stage in regard to the unplanned excision group which presented earlier stages. 77% of patients with unplanned excision had residual tumor identified after surgical re-excision. Local recurrence rate in the unplanned excision group was considerably higher 73,5% vs. 43,8%. Metastases rate was lower in planned excision group, 45,5% vs 56,3% (P > .05). The recurrence pattern in the unplanned excision group was unstable, with worse outcomes in earlier stages. CONCLUSION: The unplanned excision of a soft tissue sarcoma may compromise disease local control, with higher rates of local recurrence and metastases, and worse functional out- comes, despite further oncological treatment. We need to recognize the clinical features for malignancy risk in soft tissue lumps for a safe diagnosis to avoid inadequate resections.


Subject(s)
Neoplasm Recurrence, Local/epidemiology , Neoplasm, Residual/epidemiology , Reoperation/statistics & numerical data , Sarcoma/surgery , Soft Tissue Neoplasms/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Case-Control Studies , Female , Humans , Male , Middle Aged , Neoplasm Metastasis/pathology , Neoplasm Recurrence, Local/pathology , Neoplasm Staging/methods , Neoplasm, Residual/pathology , Prognosis , Retrospective Studies , Survival Analysis , Young Adult
10.
Cir Esp (Engl Ed) ; 97(4): 203-212, 2019 Apr.
Article in English, Spanish | MEDLINE | ID: mdl-30777256

ABSTRACT

INTRODUCTION: Soft tissue sarcomas (SFT) are a group of rare and heterogeneous neoplasms (representing less than 1% of cancer in adults and 15% in pediatric patients), for which there is no updated records in the Latin American population. This study aims to describe the current situation of patients treated at a cancer institute in Latin America. METHODS: We obtained records from 250 patients with a diagnosis of SFT, treated at the National Institute of Neoplastic Diseases of Peru (INEN) during the period 2009-2013, with a mean follow-up of 62 months. The following data were recorded: epidemiological, clinical, treatment and follow-up. The analysis of global survival was done with the Cox proportional hazards model. RESULTS: SFT showed a greater frequency in males (60.8%), with a peak incidence after 50 years of age (69.6%). Tumor location was predominantly in the lower extremities (64.4%), and the most frequent histologic subtypes were: undifferentiated pleomorphic sarcoma (34%) and liposarcomas (25.6%); clinical stage iii was the most frequent (30.8%). The 5-year overall survival rate was 63.9%, while the statistical analysis found a significant association between global survival and the variables: age (>50 years), tumor size (>5cm), depth (subfascial), histologic grade (G3), local and distant recurrence, showing shorter survival times in these groups. CONCLUSIONS: This study has clarified the epidemiology, treatment and prognosis, as well as the variables that have an impact on the survival of the Latin American patients with SFT studied.


Subject(s)
Sarcoma/epidemiology , Sarcoma/mortality , Soft Tissue Neoplasms/epidemiology , Soft Tissue Neoplasms/mortality , Adolescent , Adult , Aged , Aged, 80 and over , Child , Disease-Free Survival , Female , Follow-Up Studies , Humans , Latin America/epidemiology , Liposarcoma/pathology , Lower Extremity/pathology , Male , Middle Aged , Peru/epidemiology , Prognosis , Registries , Retrospective Studies , Sarcoma/pathology , Sarcoma/surgery , Soft Tissue Neoplasms/pathology , Soft Tissue Neoplasms/surgery , Young Adult
11.
Radiologia ; 58(6): 481-490, 2016.
Article in English, Spanish | MEDLINE | ID: mdl-27810092

ABSTRACT

Rhabdomyosarcoma is the most common soft-tissue sarcoma in children; it can appear in any part of the body. Its biological behavior varies widely, and despite the absence of specific clinical or radiological characteristics, rhabdomyosarcoma should be taken into account in the differential diagnosis of solid tumors in children. This review focuses primarily on the imaging findings and anatomical distribution of the histological subtypes of childhood rhabdomyosarcoma and secondarily on the differential findings in histological studies.


Subject(s)
Rhabdomyosarcoma, Embryonal , Child , Humans , Rhabdomyosarcoma, Embryonal/classification , Rhabdomyosarcoma, Embryonal/diagnostic imaging , Rhabdomyosarcoma, Embryonal/pathology
12.
Article in Spanish | LIVECS, LILACS | ID: biblio-1254955

ABSTRACT

El liposarcoma es un tumor maligno de origen mesenquimal. Comparado con otros tipos de neoplasias malignas, los sarcomas de partes blandas son tumores relativamente raros. Representan el 1% de todas las neoplasias y supone del 9 al 18% del total de sarcomas de partes blandas. Es una neoplasia propia de pacientes adultos, con mayor incidencia entre los 40 y los 60 años, con ligera preferencia del sexo masculino. Hasta hace tres décadas, la tendencia ante la presencia de este tipo de lesiones en las extremidades era la cirugía radical. Presentamos el caso de paciente femenino de 37 años quien presenta una tumoración en el muslo izquierdo. La biopsia incisional reportó una neoplasia maligna poco diferenciada. Ante la sospecha clínica y radiológica de la presencia de un liposarcoma fue llevada a quirófano donde se realizó compartamentectomía medial del muslo izquierdo, con colocación intraoperatoria de 12 catéteres para braquiterapia y linfadenectomía inguinofemoral izquierda. La braquiterapia es una forma de radioterapia adyuvante interna y una alternativa útil y atractiva(AU)


Liposarcoma is a malignant tumor of mesenchymal origin. Compared with other types of malignancies, soft tissue sarcomas are relatively rare tumors. Represent 1% of all malignancies and is from 9 to 18% of soft tissue sarcomas. Its an adult patients tumor, with the highest incidence between 40 and 60 years and with a slight prevalence of males. Until three decades ago, the trend in the presence of these lesions in the extremities was radical surgery. We report the case of a 37 years old female patient who has a growth on the thigh. Incisional biopsy reported a poorly differentiated malignant neoplasm. Suspecting a liposarcoma was taken to the operating room where left medial thigh compartamentectomy was made and intraoperative placement of 12 brachytherapy catheters and left inguinofemoral lymphadenectomy. Brachytherapy is a form of internal radiation and an alternative, useful and attractive adjuvant therapy(AU)


Subject(s)
Humans , Female , Adult , Sarcoma , Brachytherapy , Liposarcoma , Neoplasms , Thigh , Extremities , Growth
13.
Rev Esp Cir Ortop Traumatol ; 58(3): 160-70, 2014.
Article in Spanish | MEDLINE | ID: mdl-24629725

ABSTRACT

OBJECTIVE: To analyse the waiting periods elapsed since soft tissue sarcomas become symptomatic until their specific treatment in our unit, and to determine new strategies for the improvement of referral circuits. MATERIAL AND METHODS: This is an ambispective observational study of a cohort of 61 patients, with previously untreated soft tissue sarcomas, obtained from our Musculoskeletal Tumors Database. Several variables related to the patient, tumour, and health care circuit were analysed, as well as the different periods between the initial symptoms of the disease and the first consultation in our unit. The significance level was α=0.05. RESULTS: The mean size of the sarcomas was 11.3 cm. Thirty-six patients (59%) followed the usual circuit of the National Health System in Spain. The time elapsed since the disease became symptomatic until the first medical consultation was greater than 9.5 months, and nearly another 8.5 months to the consultation in our specific unit. Statistically significant relationships were found between the independent and dependent variables. DISCUSSION: The study shows that the care of patients with soft tissue sarcomas in our environment is far away from the times of care in our neighbouring countries. CONCLUSIONS: It is essential to make the population and health professionals aware of this disease, as well as to remember that there is a referral circuit that must be used.


Subject(s)
Leg , Referral and Consultation/statistics & numerical data , Sarcoma , Soft Tissue Neoplasms , Aged , Delayed Diagnosis , Delivery of Health Care , Female , Humans , Male , Middle Aged , Prospective Studies , Retrospective Studies , Sarcoma/diagnosis , Sarcoma/therapy , Soft Tissue Neoplasms/diagnosis , Soft Tissue Neoplasms/therapy , Time Factors
14.
Rev. cuba. pediatr ; 83(3): 302-307, jul.-set. 2011.
Article in Spanish | LILACS | ID: lil-615696

ABSTRACT

Los sarcomas de partes blandas aparecen a cualquier edad, aunque son más frecuentes en la cuarta década de la vida. Se denominan así a aquellos tumores que se originan en las estructuras que soportan el cuerpo o envuelven los órganos y tejidos, y es el rabdomiosarcoma el tumor de partes blandas más frecuente en edad pediátrica. Es rara la condición de intratabilidad, mientras que son frecuentes las recaídas tempranas y tardías después del tratamiento. Presentamos un caso de una paciente diagnosticada en etapa de recién nacida con una mala respuesta al tratamiento, con progresión en el curso de este (algo no habitual), pues, generalmente, existe una buena respuesta inicial y después puede haber recaídas


The soft parts sarcomas appear in any age, although are more frequent in the fourth decade of life. Are called in this way, those tumors originating in structures supporting the body or surrounding the organs and tissues and it is the rhabdomyosarcoma the more frequent soft parts tumor present in children. It is uncommon the irritability whereas the early and late relapses are frequent. This is the case of a patient diagnosed in the newborn stage with a poor response to treatment and progression during its course (something unusual), since generally, there is a good initial response and afterwards may be relapses

15.
Rev. cuba. pediatr ; 83(3)jul.-set. 2011.
Article in Spanish | CUMED | ID: cum-61064

ABSTRACT

Los sarcomas de partes blandas aparecen a cualquier edad, aunque son más frecuentes en la cuarta década de la vida. Se denominan así a aquellos tumores que se originan en las estructuras que soportan el cuerpo o envuelven los órganos y tejidos, y es el rabdomiosarcoma el tumor de partes blandas más frecuente en edad pediátrica. Es rara la condición de intratabilidad, mientras que son frecuentes las recaídas tempranas y tardías después del tratamiento. Presentamos un caso de una paciente diagnosticada en etapa de recién nacida con una mala respuesta al tratamiento, con progresión en el curso de este (algo no habitual), pues, generalmente, existe una buena respuesta inicial y después puede haber recaídas(AU)


The soft parts sarcomas appear in any age, although are more frequent in the fourth decade of life. Are called in this way, those tumors originating in structures supporting the body or surrounding the organs and tissues and it is the rhabdomyosarcoma the more frequent soft parts tumor present in children. It is uncommon the irritability whereas the early and late relapses are frequent. This is the case of a patient diagnosed in the newborn stage with a poor response to treatment and progression during its course (something unusual), since generally, there is a good initial response and afterwards may be relapses(AU)


Subject(s)
Humans , Female , Infant, Newborn , Pediatrics , Neoplasms/pathology , Sarcoma/pathology , Rhabdomyosarcoma/pathology , Neoplasm Metastasis/pathology , Drug Therapy/methods , General Surgery/methods , Case Reports
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