A Comprehensive Examination of UV-VIS Spectrophotometric Methods in Pharmaceutical Analysis Between 2015-2023.

BACKGROUND: Quality control is a system of validated procedures in which many samples, including active pharmaceutical ingredients and final products, are analyzed using standard or validated analytical methods. METHOD: Analytical methods used in analyzing active pharmaceutical ingredients or final products in the pharmaceutical industry can be methods registered in pharmacopeias and developed by the company itself. For this reason, published papers related to pharmaceutical analysis attract analysts and researchers' attention. In this study, pharmaceutical analysis and bioanalysis studies carried out between 2015 and 2023 were examined using Google Scholar, and the recent trends were determined for pharmaceutical analysis. Among the published papers performing conventional analytical techniques for pharmaceutical analysis, those applying UV-VIS spectrophotometry method were selected to predict a future perspective in this study. In addition to the data obtained, the current situation of the pharmaceutical industry was considered to correlate with the obtained data for pharmaceutical analysis. RESULTS: The results were presented with comparative tables and summarizing graphs. Interpreting the results allowed us to determine the trends that pharmaceutical analysis studies will lead in the future. This study can be helpful for researchers working on pharmaceutical analysis in both the industry and academia to predict future trends in pharmaceutical analysis. As a result of the literature research covering the dates 2015-2023, 56% of UV-VIS Spectrophotometric methods are used on pharmaceutical dosage forms, 27% are bulk, 16% are pure, 2% are biological materials, and 0.4% are herbal. Made from materials. Of these studies, 28% were conducted in the 200-240 nm range, 27% were conducted in the 240-300 nm range, and only 44% were conducted at >300 nm. Interpreting the results allowed us to determine the trends that pharmaceutical analysis studies will lead in the future. CONCLUSION: This study can be helpful for researchers working on pharmaceutical analysis in both the industry and academy side to predict future trends for pharmaceutical analysis.

Outcomes of patients aged ≥26 years with relapsed or refractory B-cell acute lymphoblastic leukemia in ZUMA-3 and historical trials.

Brexucabtagene autoleucel (brexu-cel) is an autologous anti-CD19 CAR T-cell therapy approved in the USA and European Union (EU) for adults with relapsed or refractory B-cell acute lymphoblastic leukemia (R/R B-ALL; aged ≥26 years in EU). Here, outcomes for patients with R/R B-ALL aged ≥26 years in ZUMA-3 treated with brexu-cel were compared with historical standard-of-care (SOC) therapy. After median follow-up of 26.8 months, the overall complete remission (CR) rate among patients treated with brexu-cel in Phase 2 (N = 43) was 72% and median overall survival (OS) was 25.4 months (95% CI, 15.9-NE). Median OS was improved in Phase 2 patients versus matched historical SOC-treated patients. Compared with aggregate historical trial data, Phase 1 and 2 patients had improved OS versus blinatumomab, inotuzumab, and chemotherapy in a matching-adjusted indirect comparison (MAIC) study. These data demonstrate clinical benefit of brexu-cel relative to SOC in patients ≥26 years with R/R B-ALL.

Scholar Metrics Scraper (SMS): automated retrieval of citation and author data.

Academic departments, research clusters and evaluators analyze author and citation data to measure research impact and to support strategic planning. We created Scholar Metrics Scraper (SMS) to automate the retrieval of bibliometric data for a group of researchers. The project contains Jupyter notebooks that take a list of researchers as an input and exports a CSV file of citation metrics from Google Scholar (GS) to visualize the group's impact and collaboration. A series of graph outputs are also available. SMS is an open solution for automating the retrieval and visualization of citation data.

Convenience stores: an obesogenic promoter in a metropolitan area of northern Mexico?

Introduction: The prevalence of obesity in the Mexican school-age (5-11 years old) population increased from 8.9 to 18.1% between 1999 and 2022. Although overweight and obesity (OW + Ob) is a complex and multifactorial phenomenon, alongside its increasing trend, changes in eating patterns as a result of obesogenic environments that promote higher energy intake have been documented. The objective of the present study was to detect possible associations between schools and their proximity to and density of convenience stores in Monterrey, Mexico from 2015 to 2018. Materials and methods: Anthropometric data were obtained from a subset of measurements of the National Registry of Weight and Height (RNPT) performed in the Monterrey Mexico metropolitan area in 2015 and 2018, and obesity prevalence was computed and classified into quintiles at the school level. Convenience store data were obtained from the National Directory of Economic Units (DNUE). The analyses consisted of densities within 400-800 m buffers, distance to the nearest stores, and cartographic visualization of the store's kernel density versus OW + Ob hotspots for both periods. Results: A total of 175,804 children in 2015 and 175,964 in 2018 belonging to 1,552 elementary schools were included in the study; during this period, OW + Ob prevalence increased from 38.7 to 39.3%, and a directly proportional relationship was found between the quintiles with the higher OW + Ob prevalence and the number of stores for both radii. Hotspots of OW + Ob ranged from 63 to 91 between 2015 and 2018, and it was visually confirmed that such spots were associated with areas with a higher density of convenience stores regardless of socioeconomic conditions. Conclusion: Although some relationships between the store's proximity/density and OW + Ob could be identified, more research is needed to gather evidence about this. However, due to the trends and the magnitude of the problem, guidelines aimed at limiting or reducing the availability of junk food and sweetened beverages on the school's periphery must be implemented to control the obesogenic environment.

The Future of Basic Science: Development of the Next Generation of Mechanistic Researchers in Female Pelvic Medicine.

INTRODUCTION AND HYPOTHESIS: The International Urogynecological Association (IUGA) brought together senior and junior members actively engaged in scholarly and educational activities for a consensus conference centered on developing a strategy for sustainable training of the next generation of mechanistic researchers in female pelvic medicine. METHODS: Four a priori identified major foci were explored in a half-day virtual consensus conference. Participants included representatives from various countries and disciplines with diverse backgrounds-clinicians, physician-scientists, and basic scientists in the fields of urogynecology, biomechanical engineering, and molecular biology. Following a keynote address, each focus area was first tackled by a dedicated breakout group, led by the Chair(s) of the most relevant IUGA committees. The break-out sessions were followed by an iterative discussion among all attendees to identify mitigating strategies to address the shortage of mechanistic researchers in the field of female pelvic medicine. RESULTS: The major focus areas included: research priorities for IUGA basic science scholar program; viable strategies for sustainable basic science mentorship; core competencies in basic science training; and the challenges of conducting complex mechanistic experiments in low-resource countries. Key gaps in knowledge and core competencies that should be incorporated into fellowship/graduate training were identified, and existing training modalities were discussed. Recommendations were made for pragmatic approaches to increasing the exposure of trainees to learning tools to enable sustainable training of the next generation of basic science researchers in female pelvic medicine worldwide. CONCLUSIONS: The attendees presented multiple perspectives to gain consensus regarding critical areas of need for training future generations of mechanistic researchers. Recommendations for a sustainable Basic Science Scholar Program were developed using IUGA as a platform. The overarching goal of such a program is to ensure a successful bench-to-bedside-and-back circuit in Urogynecology and Pelvic Reconstructive Surgery, ultimately improving lives of millions of women worldwide through scientifically rational effective preventative and therapeutic interventions.

Variations in Citations Across Databases: Implications for Journal Impact Factors.

The Journal Impact Factor (JIF) is a widely used metric for ranking journals based on the number of citations garnered by papers published over a specific timeframe. To assess the accuracy of JIF values, I compared citation counts for 30 of my own publications across six major bibliography databases: CrossRef, Web of Science, Publisher records, Google Scholar, PubMed and Scopus. The analysis revealed noteworthy variations in citation counts, ranging from 10% to over 50% between the lowest and highest citation counts. Google Scholar records the highest citation numbers, while PubMed reported the lowest. Notably, Web of Science, whose citation data are used in JIF calculations, tend to underestimate citation counts compared to other databases. These observations raise concerns about the accuracy of JIF calculation based on Web of Science's citation data. The real JIF values for most journals would differ from those annually reported by Clarivate's journal citation reports (JCR). These citation discrepancies underscore the importance of comprehensive data collection and the necessity to include additional citation sources. Not because a paper is cited in one journal rather than another should it have a less or more citation weight. Ultimately, one citation remains one citation, regardless of its origin. Clarivate Analytics may thus need to consider integrating all citation sources for more accurate JIF values. Alternatively, Google Scholar could potentially develop its own journal or citation impact based on its extensive journal citation records. However, while making adjustments to how the Journal Impact Factor is calculated can make it more mathematically precise, it doesn't address the fundamental biases built into the metric. Even with refinements, the Journal Impact Factor will remain skewed due to how it's defined and used.

Postdoctoral mentorship needs a reform.

To retain talented scientists in academia, there is a need for structural reform to postdoctoral researcher (postdoc) mentorship. These changes include mentorship training for postdocs and their mentors, formalizing postdoc mentorship networks and postdoc cohorts within a department, and incorporating mentorship development plans (MDPs) in funding decisions for principal investigators (PIs).

Analysis on Application and Funding Situation of General，Young Scholar and Regional Scholar Programs from NSFC in Field of Integrated Traditional Chinese and Western Medicine in 2023 / 中国实验方剂学杂志

By combing the application and funding situation of general， young scholar and regional scholar programs from National Natural Science Foundation of China（NSFC） in field of integrated traditional Chinese and western medicine in 2023， this paper summarizes the distribution of supporting units， application and funding hotspots， and the problems of application and funding projects in this discipline， in order to provide a reference for applicants and supporting organizations to understand the hotspot dynamics and reporting requirements of the discipline. In 2023， the discipline of integrated traditional Chinese and western medicine received a total of 2 793 applications， and there were 1 254 applications for general programs， 1 278 applications for young scholar programs， and 261 applications for regional scholar programs. The amounts of project funding obtained by the three were 145， 164 and 35， respectively， and the funding rates were 11.56%， 12.83% and 13.41% in that order. From the situation of obtaining funding， the age distribution of the project leaders who obtained funding for the general， young scholar and regional scholar programs were mainly distributed in the age of 40-46， 30-34， 38-44 years， respectively. Within the supported programs， the Chinese medicine affiliations accounted for 55.52%. With respect to research subjects， the proportion of one single Chinese herbs， or monomers， or extracts accounted for 29.4%， but the proportion of Chinese herb pairs or prescriptions accounted for 47.1%. Research hotspots included ferroptosis， bile acid metabolism， macrophages， mitochondria， microglia， exosomes， intestinal flora， microecology and so on. The current research mainly focused on the common key problems of the advantageous diseases of Chinese and western integrative medicine， but still need to be improved in the basic theories of Chinese and western medicine and multidisciplinary cross-disciplinary research.

Como indexar una revista científica usando WordPress en Google Scholar

Los avances científicos han facilitado la difusión del conocimiento, encontrándose los más recientes hallazgos rápidamente en Internet, esto ha producido la migración de las revistas desde lo impreso a lo digital, pero este proceso no siempre se realiza adecuadamente, por lo que actualmente existen revistas, y en consecuencia sus publicaciones, que no se logran encontrar en los buscadores académicos, lo que se debe al uso de los softwares inadecuados o en su defecto a una mala configuración de los que se han implementado. En esta línea la recomendación es usar Open Journal System, un software diseñado para la publicación científica, pero varias revistas usan gestores de contenido como WordPress, por su facilidad de implementación y personalización aun cuando estos presenten limitaciones en el aspecto editorial. A continuación, se expone un método para la correcta indexación de revistas confeccionadas en WordPress en el buscador Google Scholar.

Scientific advances have facilitated the dissemination of knowledge, and the latest discoveries can be easily found on the Internet. This has produced the migration of journals from print to digital; however, this process is not always done properly since there are journals, and consequently their publications, which are not currently found in academic search engines due to the inappropriate use of software or otherwise to a misconfiguration of those that have been implemented. In this line, the recommendation is to use Open Journal System, a software designed for scientific publication; on the other hand, several journals use content manager systems such as WordPress because of its easy implementation and customization even when they present editorial constrains. The following is a method for the correct indexing of journals created in WordPress in the Google Scholar search engine.

Artificial Intelligence in Scoliosis Classification: An Investigation of Language-Based Models.

Open-source artificial intelligence models are finding free application in various industries, including computer science and medicine. Their clinical potential, especially in assisting diagnosis and therapy, is the subject of increasingly intensive research. Due to the growing interest in AI for diagnostics, we conducted a study evaluating the abilities of AI models, including ChatGPT, Microsoft Bing, and Scholar AI, in classifying single-curve scoliosis based on radiological descriptions. Fifty-six posturographic images depicting single-curve scoliosis were selected and assessed by two independent neurosurgery specialists, who classified them as mild, moderate, or severe based on Cobb angles. Subsequently, descriptions were developed that accurately characterized the degree of spinal deformation, based on the measured values of Cobb angles. These descriptions were then provided to AI language models to assess their proficiency in diagnosing spinal pathologies. The artificial intelligence models conducted classification using the provided data. Our study also focused on identifying specific sources of information and criteria applied in their decision-making algorithms, aiming for a deeper understanding of the determinants influencing AI decision processes in scoliosis classification. The classification quality of the predictions was evaluated using performance evaluation metrics such as sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and balanced accuracy. Our study strongly supported our hypothesis, showing that among four AI models, ChatGPT 4 and Scholar AI Premium excelled in classifying single-curve scoliosis with perfect sensitivity and specificity. These models demonstrated unmatched rater concordance and excellent performance metrics. In comparing real and AI-generated scoliosis classifications, they showed impeccable precision in all posturographic images, indicating total accuracy (1.0, MAE = 0.0) and remarkable inter-rater agreement, with a perfect Fleiss' Kappa score. This was consistent across scoliosis cases with a Cobb's angle range of 11-92 degrees. Despite high accuracy in classification, each model used an incorrect angular range for the mild stage of scoliosis. Our findings highlight the immense potential of AI in analyzing medical data sets. However, the diversity in competencies of AI models indicates the need for their further development to more effectively meet specific needs in clinical practice.

Impact of SCHOLAR-1 Criteria on Chimeric Antigen Receptor T Cell Therapy Efficacy in Aggressive B Lymphoma: A Real-World GELTAMO/GETH Study.

In the pre-chimeric antigen receptor T cell (CAR-T) therapy era, the SCHOLAR-1 study identified a group of patients with refractory aggressive B cell lymphoma (ABCL) with particularly poor prognoses. We recently published our real-world data from Spain, focused on this SCHOLAR-1 refractory group, and compared patients who underwent CAR-T therapy with the previous standard of care. In this study, we found that the efficacy of CAR-T therapy in refractory patients, in terms of progression-free survival (PFS) and overall survival (OS), was superior to that of the treatments available in the pre-CAR-T era. The main objective of these new analyses was to analyze treatment efficacy in terms of response rates and survival for patients with ABCL with or without the SCHOLAR-1 criteria. In addition, we analyzed the prognostic impact of each SCHOLAR-1 criterion independently. Our study aimed to assess the prognostic impact of SCHOLAR-1 criteria on ABCL patients treated with CAR-T therapy in Spain. This multicenter, retrospective, observational study. We included all adult patients treated with commercially available CAR-T cell products and diagnosed with ABCL different from primary mediastinal large B cell lymphoma between February 2019 and July 2022. Patients meeting any SCHOLAR-1 criteria (progressive disease as the best response to any line of therapy, stable disease as the best response to ≥4 cycles of first-line therapy or ≥2 cycles of later-line therapy, or relapse at <12 months after autologous stem cell transplantation [auto-SCT]) in the line of treatment before CAR-T therapy (SCHOLAR-1 group) were compared with those not meeting any of these criteria (non-SCHOLAR-1 group). To analyze the prognostic impact of individual SCHOLAR-1 criteria, all the patients who met any of the SCHOLAR-1 criteria at any time were included to assess whether these criteria have the same prognostic impact in the CAR-T era. In addition, patients were grouped according to whether they were refractory to the first line of treatment, refractory to the last line of treatment, or relapsed early after auto-SCT. The PFS and OS were calculated from the time of appearance of the SCHOLAR-1 refractoriness criteria. Of 329 patients treated with CAR-T (169 with axi-cel and 160 with tisa-cel), 52 were in the non-SCHOLAR-1 group and 277 were in the SCHOLAR-1 group. We found significantly better outcomes in the non-SCHOLAR-1 patients compared with the SCHOLAR-1 patients (median PFS of 12.2 and 3.3 months, respectively; P = .009). In addition, axi-cel showed better results in terms of efficacy than tisa-cel for both the non-SCHOLAR-1 group (hazard ratio [HR] for PFS, 2.7 [95% confidence interval (CI), 1.1 to 6.7; P = .028]; HR for OS, 7.1 [95% CI, 1.5 to 34.6; P = .015]) and SCHOLAR-1 group (HR for PFS, 1.8 [95% CI, 1.3 to 2.5; P < .001]; HR for OS, 1.8 [95% CI, 1.2 to 2.6; P = .002]), but also significantly more toxicity. Finally, separately analyzing the prognostic impact of each SCHOLAR-1 criterion revealed that refractoriness to the last line of treatment was the variable with the most significant impact on survival. In conclusion, SCHOLAR-1 refractoriness criteria notably influence the efficacy of CAR-T therapy. In our experience, axi-cel showed better efficacy than tisa-cel for both SCHOLAR-1 and non-SCHOLAR-1 patients. Refractoriness to the last line of treatment was the variable with the most significant impact on survival in the CAR-T therapy era.

Moving Research-Based Learning in Life Sciences Upstream, and Beyond Borders: An International Group Research Project for High School Youth.

International cooperation beyond borders, institutions, and intergenerationally is an important aspect of science and research-based learning. Timing of learning also matters. Early exposure to group research-based learning can potentially have lasting positive impacts on youth and their careers in life sciences. Here, we report our work on the International Group Project (IGP), which builds on the International Biology Olympiad (IBO) organized in Yerevan, Armenia, in 2022. The IBO is an annual international competition for high school students held since 1990 around the world. We envisioned the IGP as a novel opportunity for life sciences research-based education among youth. We formed diverse IGP research teams 2 months before the IBO, and comprised high school students from 32 countries, communicating in a digital environment via videoconferencing. Each team formulated a research question in an IGP theme from five domains of life sciences: "Biomedicine," "Molecular and cell biology," "Bioinformatics and Artificial Intelligence," "Bionics and Biomimicry," "Across Species." Subsequently, team members collectively solved their research question by applying life sciences methodologies under supervision from a facilitator scientist. Each team created a poster based on their research and presented in-person to the public at a satellite activity at the IBO. A special subcommittee of the IBO International Jury graded posters and allocated prizes based on scientific ingenuity and presentation quality. This experience from the IGP lends evidence to the feasibility of research-based learning in life sciences for high school youth beyond borders. Moving research-based learning upstream and internationally is well poised to advance 21st century life sciences from both interdisciplinary and intergenerational standpoints. The historic impact of the COVID-19 pandemic suggests that youth engagement in research-based learning and innovation in life sciences is timely.

The effect of the Educational Scholar Program as a longitudinal faculty development program on the capability of educators as scholars.

INTRODUCTION: The Educational Scholar Program (ESP) is designed and implemented as a longitudinal and institution-based faculty development program. The present study aimed to assess the effect of the ESP on educators' capabilities to undertake SoTL activities associated with their scholar role. METHODS: This study was conducted from 2017 to 2022. The participants (n = 64) were educators in six schools of Shahid Sadoughi University of Medical Sciences. The ESP was a faculty development program that consisted of training and project-based stages. The educators experienced small-group learning, self-directed learning, and reflective assignments in the training stage. In the second stage, the educators completed a SoTL (Scholarship of Teaching and Learning) project. Learner-related outcomes based on Kirkpatrick model was assessed. The reaction of educators (satisfaction, active participation in the ESP, and the perception of mentoring sessions) was assessed by three questionnaires (Reaction level). The educators' learning was evaluated by modified essay questions and their project reports (Learning and Behavior levels). Outputs of the ESP including journal publications, abstracts presented at meetings or congresses, grant funding, awards in educational festivals, promotions, projects with ongoing implementation following the ESP, and conducting further SoTL projects after ESP were assessed quantitatively over two years after participating in the ESP (Results level). Data were summarized by descriptive statistics (mean, percentage, SD, 95% Confidence Interval (CI)). Cut-off scores of the instruments was calculated with a standard setting method which introduced by Cohen-Schotanus and Van DerVleuten. Data analyzed by One-sample t-test. RESULTS: Sixty-four of 72 (89%) educators completed the ESP. The mean (CI) satisfaction score of educators was 42 (CI: 26.92-58.28), the active participation was 92 (CI: 80.24-103.76). The scores of the mentoring assessment from the perspective of the educators were reported at 90 (CI: 78.24- 101.76). The mean (95%CI) learning scores in the essay examination were 88 (CI: 70.36- 105.64), and project assessment were 90 (CI: 78.24- 101.76). The results showed the educators' scores in reaction and learning significantly higher than the cut-off scores. (P < 0.05). Most projects were conducted in curriculum development and assessment/evaluation domains. The number of projects with ongoing implementation over the two years following the ESP and the acquisition of grants was higher than other outputs in the results level. CONCLUSION: The ESP, as an institute-based longitudinal program, enhanced the learner-related outcomes (in four levels of reaction, learning, behavior, and results). The creation of practical learning and supportive mechanisms influenced on the results. The outcomes of ESP indicated that the educators prepared to conduct SoTL activities in their educational community.

Do Current Lung Cancer Clinical Trials Represent All Patient Populations Including Minorities?

The under-representation of racial, sexual, and gender minorities in cancer clinical trials has long been a deficit in clinical cancer research. This review aims to survey current literature to determine the participation of minorities in the United States in lung cancer clinical trials and to find educational methods that have been studied and researched in order to improve patient clinical trial enrollment. A literature search of relevant articles published since 2015 was conducted using PubMed and Google Scholar. Clinical trials conducted in the United States from Clinicaltrials.gov were also collected to determine minority patient enrollment in lung cancer clinical trials. The results of the literature search yielded 6 relevant articles about racial minority representation in lung cancer clinical trials and one relevant article about LGBTQ+ minority representation in cancer clinical trials. Collectively, the literature highlighted the under-representation of racial minorities (such as Black, Hispanic, and American Indian) in clinical trials. Many articles showed that disparities in enrollment were less significant for Asian patients with lung cancer. However, many articles did not mention minorities like Middle Eastern/North Africans and failed to mention the lack of distinguishment of South Asian minorities from Pacific Asian minorities. The findings of this literature review support the idea that current lung cancer clinical trials lack representation of minority patient populations in the United States. The inclusion of racial, sexual, and gender diversity in clinical trial patient populations will aid providers in determining appropriate therapeutics and could potentially improve lung cancer outcomes. Future directions for improving diversity in lung cancer clinical trial enrollment include the utilization of various educational tools to increase minority patient participation in trials, the inclusion of detailed demographic data in cancer clinical trial analysis, and the recruitment of providers and research staff from various minorities to conduct cancer clinical trials.

Planetary health as a main topic for the qualification in digital teaching - a project report.

Aim: To do justice to the need for planetary health in medical education, these are the aims of the online elective course "Planetary Health in Medical Education" (ME elective):1. Enable students to plan and realize their own course sessions on planetary health;2. Encourage communication among university medical faculties regarding planetary health in medical education;3. Reinforce competency in digital teaching and amplify the expert role as multiplicator among students pursuing a Master's degree in Medicinal Education (MME). Method: The development of the ME elective followed Kern's six-step approach to curriculum development by means of cooperation between the German Medical Students' Association (Bundesvertretung der Medizinstudierenden in Deutschland, abbreviated as bvmd), and the MME study program. Based on general and specific needs analyses, core learning objectives regarding planetary health, medical education and digital education were identified in the National Catalogue of Learning Objectives in Undergraduate Medical Education (NKLM) and the MME study program and relevant teaching methods were selected. Results: The ME elective, consisting of two contact hours per week per semester, was established at 13 medical schools as a four-phase course:1. Introduction to medical education using examples from planetary health;2. Lesson planning on a topic in planetary health under the supervision of MME students;3. Course sessions held by the undergraduate students; and4. Networking with the MME study program through participation in digital courses on planetary health and the pilot OSCE on planetary health.A total of 24 students attended the pilot in the 2022 summer semester. Conclusion: The topic of planetary health combines interests that span many subjects and semester levels. As a collaborative, interdisciplinary and interprofessional subject, it lends itself to training students in a trans-institutional elective course to become multiplicators.

Google Scholar as a Sole Literature Source for Meta-analyses in Otolaryngology Head and Neck Surgery.

The strength of meta-analyses lies in the synthesis of data from multiple studies. Current guidelines require a thorough systematic search to maximize results, which usually includes searching multiple academic search systems (ASS). Google Scholar (GS) is considered a promising tool for searching the scientific literature. We aimed to determine whether GS is a valid and sufficient solitary data source for meta-analyses in the field of otolaryngology. Selected ENT-HNS journal was searched for meta-analyses published between 2010 and 2021 that adhered to the systematic reviews and meta-analyses guidelines and precisely followed the search algorithm. The latter was reproduced with GS, and the position of each enrolled study in each meta-analysis was determined. Ten meta-analyses were enrolled, the total number of search results ranged from 57 to 17,949. The number of GS search results was significantly greater than those of other ASS combinations (range 1,360-25,400, P = .006). The number of included papers for each meta-analysis ranged from 5 to 26. The position of all enrolled papers throughout GS searching was in the first 200 GS results in four of 10 meta-analyses. The reference lists of all included papers in the first 200 GS results identified 106 papers out of 108 (98%), while searching until the 500th GS output results identified 107 papers out of 108 papers (99%). GS can serve as a solitary ASS for systematic literature reviews and meta-analyses in the field of otolaryngology. Searching the first 500 or 200 results and including reference lists yields 99% and 98% coverage, respectively.

The relation between social media mentions and academic citations in orthodontic journals: A preliminary study.

BACKGROUND: To study the relation between social media mentions and academic citations for articles published in peer-reviewed orthodontic journals. METHODS: Articles published in early 2018 in seven peer-reviewed orthodontic journals were retrospectively analyzed in September 2022. Citation counts of the articles were evaluated using two databases: Google Scholar (GS) and Web of Science (WoS). The Altmetric Attention Score, Twitter, Facebook mentions, and Mendeley reads were tracked using the Altmetric Bookmarklet. The citation counts and social media mentions were correlated using Spearman rho. RESULTS: A total of 84 articles were identified during the initial search; 64 (76%) were original studies and systematic review articles and included in the analysis. A total of 38% of the articles had at least one mention on social media. Over the study period, the average number of citations of the articles mentioned on social media was higher than the non-mentioned articles for GS and WoS, respectively. Moreover, significant positive correlations existed between the Altmetric Attention Score and the number of citations in GS and WoS (rs = 0.31, P = 0.001 and rs = 0.26, P = 0.04). CONCLUSIONS: Social media mentions and citations of articles published in peer-reviewed orthodontic journals are correlated, with a clear difference in the number of citations in articles mentioned on social media versus those not mentioned, indicating possible increased reach of articles disseminated on social media.

Modeling a successful citation trajectory structure for scholar's impact evaluation in Israeli academia.

One of the main concerns of researchers and institutions is how to assess the future performance of scholars and identify their potential to become successful scientists. In this study, we model scholarly success in terms of the probability of a scholar belonging to a group of highly impactful scholars as determined by their citation trajectory structures. To this end, we developed a new set of impact measures based on a scholar's citation trajectory structure (rather than on absolute citation or h-index rates), that show a stable trend and scale for highly impactful scholars, independent of their field of study, seniority and citation index. These measures were then incorporated as influence factors into the logistic regression models and used as features for probabilistic classifiers based on these models to identify the successful scholars in the heterogeneous corpus of 400 of most and least cited professors from two Israeli universities. From the practical point of view, the study may yield useful insights and serve as an aid in making promotion decisions by institutions, as well as a self-assessment tool for researchers who strive to increase their academic influence and become leaders in their field.

PHYSICAL EDUCATION TEACHERS' UNDERSTANDING REGARDING THE ACCESSIBILITY DIMENSIONS IN SCHOOL / COMPRENSIÓN DE LOS PROFESORES DE EDUCACIÓN FÍSICA SOBRE LAS DIMENSIONES DE ACCESIBILIDAD EN LA ESCUELA / COMPREENSÃO DE PROFESSORES DE EDUCAÇÃO FÍSICA EM RELAÇÃO AS DIMENSÕES DE ACESSIBILIDADE NA ESCOLA

This research aimed to analyze the comprehension of Physical Education teachers about accessibility in schools and in the spaces in which the Physical Education classes take place. Two Physical Education teachers participated in the study - one from the state education network and another from the municipal education network. A semi-structured interview, consisting of questions about the teachers' understanding of the different accessibilities (architectonic, communicational, methodological, instrumental, programmatic, and attitudinal) proposed by Sassaki (2010). The results showed that the schools do not provide all the dimensions of accessibility, being the architectonic the most present of them, although it doesn't guarantee accessibility for all kinds of disabilities. Communicational, methodological, and attitudinal accessibilities are being provided. Instrumental accessibility is absent in one of the schools, and in the other, there are accessible materials, sometimes adapted ones. The programmatic accessibility was found in one of the schools, but not in the other. Therefore, despite not providing all dimensions of accessibility, the schools are taking action to better serve students with disabilities.

Esta investigación tuvo como objetivo analizar la comprensión de los profesores de Educación Física sobre la accesibilidad en las escuelas y en los espacios en los que se desarrollan las clases de Educación Física. Participaron del estudio dos profesoras de Educación Física, una de la red estatal de educación y otra de la red municipal de educación. Una entrevista semiestructurada, compuesta por preguntas sobre la comprensión de los docentes sobre los diferentes tipos de accesibilidad (arquitectónica, comunicacional, metodológica, instrumental, programática y actitudinal) propuestas por Sassaki (2010). Los resultados mostraron que las escuelas no contemplan todas las dimensiones de la accesibilidad, siendo la arquitectónica la más presente, aunque la accesibilidad no está garantizada para todo tipo de discapacidad. Además, se están proporcionando accesibilidades comunicacionales, metodológicas y actitudinales. La accesibilidad instrumental está ausente en una de las escuelas, y en la otra hay materiales accesibles, a veces adaptados. La accesibilidad programática se encontró en una de las escuelas, pero no en la otra. Por lo tanto, a pesar de no contemplar todas las dimensiones de accesibilidad, las escuelas están tomando medidas para servir mejor a los estudiantes con discapacidades.

O objetivo dessa pesquisa foi analisar as compreensões de professores de Educação Física sobre acessibilidade nas escolas e nos espaços das aulas de Educação Física. Participaram duas professoras de Educação Física, uma da rede municipal e outra da rede estadual. Foi realizada uma entrevista semiestruturada, em que foram realizadas perguntas sobre o entendimento das professoras sobre as acessibilidades (arquitetônica, comunicacional, metodológica, instrumental, programática e atitudinal) propostas por Sassaki (2010). Os resultados mostraram que as escolas não proporcionam todas as dimensões de acessibilidade, sendo a acessibilidade arquitetônica a mais presente, embora não garanta a acessibilidade para todas as deficiências. As acessibilidades comunicacional, metodológica e atitudinal são proporcionadas. A acessibilidade instrumental está ausente em uma das escolas e, na outra, os materiais são acessíveis e, por vezes, adaptados. A acessibilidade programática foi identificada em uma das escolas, mas não na outra. Portanto, apesar de não proporcionarem todas as dimensões de acessibilidade, as escolas estão realizando ações para melhor atender os alunos com deficiência.

Activating Specific Handball's Defensive Motor Behaviors in Young Female Players: A Non-Linear Approach.

Traditional models to train and teach young players in team sports assume that athletes learn as linear systems. However, an actual methodology called Non-Linear Pedagogy (NLP) accounts for the fact that the players and the team are complex dynamic systems. Experiences in handball under this methodology are scarce; due to this, an observational study has been conducted with a follow-up, idiographic and multidimensional design, in which 14 female school handball players belonging to four different local teams in Santiago, Chile (age = 15.55 + 0.51) agreed to participate in three special handball training sessions with the use of the NLP methodology where three different constraints were used. Descriptive analysis with the Chi-squared test showed a total of 252 observations where most of the variables were dependent on the constraints (p ≤ 0.001). Frequency showed that mainly "Defense in Line of progression" and "Proximal contact" were the most activated variables, followed by "Harassment" and "Deterrence" for all constraints. However, only constraint 2 highly activated two collective motor behaviors, while the rest only did it with individual motor behaviors. It is concluded that the constraints used in training seem to be effective in activating a group of defensive handball motor behaviors, specifically those that are basic for female school handball players.