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1.
Data Brief ; 54: 110271, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38962205

ABSTRACT

ArzEn-MultiGenre is a parallel dataset of Egyptian Arabic song lyrics, novels, and TV show subtitles that are manually translated and aligned with their English counterparts. The dataset contains 25,557 segment pairs that can be used to benchmark new machine translation models, fine-tune large language models in few-shot settings, and adapt commercial machine translation applications such as Google Translate. Additionally, the dataset is a valuable resource for research in various disciplines, including translation studies, cross-linguistic analysis, and lexical semantics. The dataset can also serve pedagogical purposes by training translation students and aid professional translators as a translation memory. The contributions are twofold: first, the dataset features textual genres not found in existing parallel Egyptian Arabic and English datasets, and second, it is a gold-standard dataset that has been translated and aligned by human experts.

2.
Cogn Neuropsychol ; : 1-16, 2024 Jul 06.
Article in English | MEDLINE | ID: mdl-38970815

ABSTRACT

The exploration of naming error patterns in aphasia provides insights into the cognitive processes underlying naming performance. We investigated how semantic and phonological abilities correlate and how they influence naming performance in aphasia. Data from 296 individuals with aphasia, drawn from the Moss Aphasia Psycholinguistics Project Database, were analyzed using a structural equation model. The model incorporated latent variables for semantics and phonology and manifest variables for naming accuracy and error patterns. There was a moderate positive correlation between semantics and phonology after controlling for overall aphasia severity. Both semantic and phonological abilities influenced naming accuracy. Semantic abilities are negatively related to semantic, mixed, unrelated errors and no responses. Interestingly, phonology positively affected semantic errors. Additionally, phonological abilities are negatively related to each of the phonological and neologism errors. These results highlight the role of semantic and phonological skills on naming performance in aphasia and reveal a relationship between these cognitive processes.

3.
Med Phys ; 2024 Jul 09.
Article in English | MEDLINE | ID: mdl-38980220

ABSTRACT

An Addendum to the AAPM's TG-51 protocol for the determination of absorbed dose to water is presented for electron beams with energies between 4 MeV and 22 MeV ( 1.70 cm ≤ R 50 ≤ 8.70 cm $1.70\nobreakspace {\rm cm} \le R_{\text{50}} \le 8.70\nobreakspace {\rm cm}$ ). This updated formalism allows simplified calibration procedures, including the use of calibrated cylindrical ionization chambers in all electron beams without the use of a gradient correction. New k Q $k_{Q}$ data are provided for electron beams based on Monte Carlo simulations. Implementation guidance is provided. Components of the uncertainty budget in determining absorbed dose to water at the reference depth are discussed. Specifications for a reference-class chamber in electron beams include chamber stability, settling, ion recombination behavior, and polarity dependence. Progress in electron beam reference dosimetry is reviewed. Although this report introduces some major changes (e.g., gradient corrections are implicitly included in the electron beam quality conversion factors), they serve to simplify the calibration procedure. Results for absorbed dose per linac monitor unit are expected to be up to approximately 2 % higher using this Addendum compared to using the original TG-51 protocol.

4.
Sci Rep ; 14(1): 15549, 2024 Jul 05.
Article in English | MEDLINE | ID: mdl-38969745

ABSTRACT

Interacting with objects in our environment requires determining their locations, often with respect to surrounding objects (i.e., allocentrically). According to the scene grammar framework, these usually small, local objects are movable within a scene and represent the lowest level of a scene's hierarchy. How do higher hierarchical levels of scene grammar influence allocentric coding for memory-guided actions? Here, we focused on the effect of large, immovable objects (anchors) on the encoding of local object positions. In a virtual reality study, participants (n = 30) viewed one of four possible scenes (two kitchens or two bathrooms), with two anchors connected by a shelf, onto which were presented three local objects (congruent with one anchor) (Encoding). The scene was re-presented (Test) with 1) local objects missing and 2) one of the anchors shifted (Shift) or not (No shift). Participants, then, saw a floating local object (target), which they grabbed and placed back on the shelf in its remembered position (Response). Eye-tracking data revealed that both local objects and anchors were fixated, with preference for local objects. Additionally, anchors guided allocentric coding of local objects, despite being task-irrelevant. Overall, anchors implicitly influence spatial coding of local object locations for memory-guided actions within naturalistic (virtual) environments.


Subject(s)
Semantics , Virtual Reality , Humans , Female , Male , Adult , Young Adult , Space Perception/physiology , Memory/physiology
5.
Cogn Emot ; : 1-11, 2024 Jul 07.
Article in English | MEDLINE | ID: mdl-38973172

ABSTRACT

While previous research has found an in-group advantage (IGA) favouring native speakers in emotional prosody perception over non-native speakers, the effects of semantics on emotional prosody perception remain unclear. This study investigated the effects of semantics on emotional prosody perception in Chinese words and sentences for native and non-native Chinese speakers. The critical manipulation was the congruence of prosodic (positive, negative) and semantic (positive, negative, and neutral) valence. Participants listened to a series of audio clips and judged whether the emotional prosody was positive or negative for each utterance. The results revealed an IGA effect: native speakers perceived emotional prosody more accurately and quickly than non-native speakers in Chinese words and sentences. Furthermore, a semantic congruence effect was observed in Chinese words, where both native and non-native speakers recognised emotional prosody more accurately in the semantic-prosody congruent condition than in the incongruent condition. However, in Chinese sentences, this congruence effect was only present for non-native speakers. Additionally, the IGA effect and semantic congruence effect on emotional prosody perception were influenced by prosody valence. These findings illuminate the role of semantics in emotional prosody perception, highlighting perceptual differences between native and non-native Chinese speakers.

6.
Big Data ; 2024 Jul 10.
Article in English | MEDLINE | ID: mdl-38984408

ABSTRACT

Extracting meaningful patterns of human mobility from accumulating trajectories is essential for understanding human behavior. However, previous works identify human mobility patterns based on the spatial co-occurrence of trajectories, which ignores the effect of activity content, leaving challenges in effectively extracting and understanding patterns. To bridge this gap, this study incorporates the activity content of trajectories to extract human mobility patterns, and proposes acontent-aware mobility pattern model. The model first embeds the activity content in distributed continuous vector space by taking point-of-interest as an agent and then extracts representative and interpretable mobility patterns from human trajectory sets using a derived topic model. To investigate the performance of the proposed model, several evaluation metrics are developed, including pattern coherence, pattern similarity, and manual scoring. A real-world case study is conducted, and its experimental results show that the proposed model improves interpretability and helps to understand mobility patterns. This study provides not only a novel solution and several evaluation metrics for human mobility patterns but also a method reference for fusing content semantics of human activities for trajectory analysis and mining.

7.
Magn Reson Med ; 2024 Jul 10.
Article in English | MEDLINE | ID: mdl-38987985

ABSTRACT

PURPOSE: The transverse relaxation time T 2 $$ {}_2 $$ holds significant relevance in clinical applications and research studies. Conventional T 2 $$ {}_2 $$ mapping approaches rely on spin-echo sequences, which require lengthy acquisition times and involve high radiofrequency (RF) power deposition. An alternative gradient echo (GRE) phase-based T 2 $$ {}_2 $$ mapping method, utilizing steady-state acquisitions at one small RF spoil phase increment, was recently demonstrated. Here, a modified magnitude- and phase-based T 2 $$ {}_2 $$ mapping approach is proposed, which improves T 2 $$ {\mathrm{T}}_2 $$ estimations by simultaneous fitting of T 1 $$ {\mathrm{T}}_1 $$ and signal amplitude ( A ∝ P D $$ A\propto PD $$ ) at three or more RF spoiling phase increments, instead of assuming a fixed T 1 $$ {\mathrm{T}}_1 $$ value. METHODS: The feasibility of the magnitude-phase-based method was assessed by simulations, in phantom and in vivo experiments using skipped-CAIPI three-dimensional-echo-planar imaging (3D-EPI) for rapid GRE imaging. T 2 $$ {\mathrm{T}}_2 $$ , T 1 $$ {\mathrm{T}}_1 $$ and PD estimations obtained by our method were compared to T 2 $$ {\mathrm{T}}_2 $$ of the phase-based method and T 1 $$ {\mathrm{T}}_1 $$ and PD of spoiled GRE-based multi-parameter mapping using a multi-echo version of the same sequence. RESULTS: The agreement of the proposed T 2 $$ {\mathrm{T}}_2 $$ with ground truth and reference T 2 $$ {\mathrm{T}}_2 $$ values was higher than that of phase-based T 2 $$ {\mathrm{T}}_2 $$ in simulations and in phantom data. While phase-based T 2 $$ {\mathrm{T}}_2 $$ overestimation increases with actual T 2 $$ {\mathrm{T}}_2 $$ and T 1 $$ {\mathrm{T}}_1 $$ , the proposed method is accurate over a large range of physiologically meaningful T 2 $$ {\mathrm{T}}_2 $$ and T 1 $$ {\mathrm{T}}_1 $$ values. At the same time, precision is improved. In vivo results were in line with these observations. CONCLUSION: Accurate magnitude-phase-based T 2 $$ {}_2 $$ mapping is feasible in less than 5 min scan time for 1 mm nominal isotropic whole-head coverage at 3T and 7T.

8.
Magn Reson Med ; 2024 Jul 10.
Article in English | MEDLINE | ID: mdl-38988054

ABSTRACT

PURPOSE: To standardize T 2 $$ {}_2 $$ -weighted images from clinical Turbo Spin Echo (TSE) scans by generating corresponding T 2 $$ {}_2 $$ maps with the goal of removing scanner- and/or protocol-specific heterogeneity. METHODS: The T 2 $$ {}_2 $$ map is estimated by minimizing an objective function containing a data fidelity term in a Virtual Conjugate Coils (VCC) framework, where the signal evolution model is expressed as a linear constraint. The objective function is minimized by Projected Gradient Descent (PGD). RESULTS: The algorithm achieves accuracy comparable to methods with customized sampling schemes for accelerated T 2 $$ {}_2 $$ mapping. The results are insensitive to the tunable parameters, and the relaxed background phase prior produces better T 2 $$ {}_2 $$ maps compared to the strict real-value enforcement. It is worth noting that the algorithm works well with challenging T 2 $$ {}_2 $$ w-TSE data using typical clinical parameters. The observed normalized root mean square error ranges from 6.8% to 12.3% over grey and white matter, a clinically common level of quantitative map error. CONCLUSION: The novel methodological development creates an efficient algorithm that allows for T 2 $$ {}_2 $$ map generated from TSE data with typical clinical parameters, such as high resolution, long echo train length, and low echo spacing. Reconstruction of T 2 $$ {}_2 $$ maps from TSE data with typical clinical parameters has not been previously reported.

9.
Magn Reson Med ; 2024 Jul 10.
Article in English | MEDLINE | ID: mdl-38988040

ABSTRACT

PURPOSE: To explore the high signal-to-noise ratio (SNR) efficiency of interleaved multishot 3D-EPI with standard image reconstruction for fast and robust high-resolution whole-brain quantitative susceptibility (QSM) and R 2 ∗ $$ {R}_2^{\ast } $$ mapping at 7 and 3T. METHODS: Single- and multi-TE segmented 3D-EPI is combined with conventional CAIPIRINHA undersampling for up to 72-fold effective gradient echo (GRE) imaging acceleration. Across multiple averages, scan parameters are varied (e.g., dual-polarity frequency-encoding) to additionally correct for B 0 $$ {\mathrm{B}}_0 $$ -induced artifacts, geometric distortions and motion retrospectively. A comparison to established GRE protocols is made. Resolutions range from 1.4 mm isotropic (1 multi-TE average in 36 s) up to 0.4 mm isotropic (2 single-TE averages in approximately 6 min) with whole-head coverage. RESULTS: Only 1-4 averages are needed for sufficient SNR with 3D-EPI, depending on resolution and field strength. Fast scanning and small voxels together with retrospective corrections result in substantially reduced image artifacts, which improves susceptibility and R 2 ∗ $$ {R}_2^{\ast } $$ mapping. Additionally, much finer details are obtained in susceptibility-weighted image projections through significantly reduced partial voluming. CONCLUSION: Using interleaved multishot 3D-EPI, single-TE and multi-TE data can readily be acquired 10 times faster than with conventional, accelerated GRE imaging. Even 0.4 mm isotropic whole-head QSM within 6 min becomes feasible at 7T. At 3T, motion-robust 0.8 mm isotropic whole-brain QSM and R 2 ∗ $$ {R}_2^{\ast } $$ mapping with no apparent distortion in less than 7 min becomes clinically feasible. Stronger gradient systems may allow for even higher effective acceleration rates through larger EPI factors while maintaining optimal contrast.

10.
Acta Physiol (Oxf) ; : e14191, 2024 Jun 19.
Article in English | MEDLINE | ID: mdl-38895950

ABSTRACT

AIM: Physical activity (PA) is a key component for brain health and Reserve, and it is among the main dementia protective factors. However, the neurobiological mechanisms underpinning Reserve are not fully understood. In this regard, a noradrenergic (NA) theory of cognitive reserve (Robertson, 2013) has proposed that the upregulation of NA system might be a key factor for building reserve and resilience to neurodegeneration because of the neuroprotective role of NA across the brain. PA elicits an enhanced catecholamine response, in particular for NA. By increasing physical commitment, a greater amount of NA is synthetised in response to higher oxygen demand. More physically trained individuals show greater capabilities to carry oxygen resulting in greater Vo 2 max $$ {\mathrm{Vo}}_{2_{\mathrm{max}}} $$ - a measure of oxygen uptake and physical fitness (PF). METHODS: We hypothesized that greater Vo 2 max $$ {\mathrm{Vo}}_{2_{\mathrm{max}}} $$ would be related to greater Locus Coeruleus (LC) MRI signal intensity. In a sample of 41 healthy subjects, we performed Voxel-Based Morphometry analyses, then repeated for the other neuromodulators as a control procedure (Serotonin, Dopamine and Acetylcholine). RESULTS: As hypothesized, greater Vo 2 max $$ {\mathrm{Vo}}_{2_{\mathrm{max}}} $$ related to greater LC signal intensity, and weaker associations emerged for the other neuromodulators. CONCLUSION: This newly established link between Vo 2 max $$ {\mathrm{Vo}}_{2_{\mathrm{max}}} $$ and LC-NA system offers further understanding of the neurobiology underpinning Reserve in relationship to PA. While this study supports Robertson's theory proposing the upregulation of the NA system as a possible key factor building Reserve, it also provides ground for increasing LC-NA system resilience to neurodegeneration via Vo 2 max $$ {\mathrm{Vo}}_{2_{\mathrm{max}}} $$ enhancement.

11.
Brain Struct Funct ; 2024 Jun 25.
Article in English | MEDLINE | ID: mdl-38914895

ABSTRACT

Optic Aphasia (OA) and Associative Visual Agnosia (AVA) are neuropsychological disorders characterized by impaired naming on visual presentation. From a cognitive point of view, while stimulus identification is largely unimpaired in OA (where access to semantic knowledge is still possible), in AVA it is not. OA has been linked with right hemianopia and disconnection of the occipital right-hemisphere (RH) visual processing from the left hemisphere (LH) language areas.In this paper, we describe the case of AA, an 81-year-old housewife suffering from a deficit in naming visually presented stimuli after left occipital lesion and damage to the interhemispheric splenial pathway. AA has been tested through a set of tasks assessing different levels of visual object processing. We discuss behavioral performance as well as the pattern of lesion and disconnection in relation to a neurocognitive model adapted from Luzzatti and colleagues (1998). Despite the complexity of the neuropsychological picture, behavioral data suggest that semantic access from visual input is possible, while a lesion-based structural disconnectome investigation demonstrated the splenial involvement.Altogether, neuropsychological and neuroanatomical findings support the assumption of visuo-verbal callosal disconnection compatible with a diagnosis of OA.

12.
Neurobiol Lang (Camb) ; 5(2): 385-408, 2024.
Article in English | MEDLINE | ID: mdl-38911462

ABSTRACT

The language network, comprised of brain regions in the left frontal and temporal cortex, responds robustly and reliably during language comprehension but shows little or no response during many nonlinguistic cognitive tasks (e.g., Fedorenko & Blank, 2020). However, one domain whose relationship with language remains debated is semantics-our conceptual knowledge of the world. Given that the language network responds strongly to meaningful linguistic stimuli, could some of this response be driven by the presence of rich conceptual representations encoded in linguistic inputs? In this study, we used a naturalistic cognition paradigm to test whether the cognitive and neural resources that are responsible for language processing are also recruited for processing semantically rich nonverbal stimuli. To do so, we measured BOLD responses to a set of ∼5-minute-long video and audio clips that consisted of meaningful event sequences but did not contain any linguistic content. We then used the intersubject correlation (ISC) approach (Hasson et al., 2004) to examine the extent to which the language network "tracks" these stimuli, that is, exhibits stimulus-related variation. Across all the regions of the language network, meaningful nonverbal stimuli elicited reliable ISCs. These ISCs were higher than the ISCs elicited by semantically impoverished nonverbal stimuli (e.g., a music clip), but substantially lower than the ISCs elicited by linguistic stimuli. Our results complement earlier findings from controlled experiments (e.g., Ivanova et al., 2021) in providing further evidence that the language network shows some sensitivity to semantic content in nonverbal stimuli.

13.
Neuropsychologia ; 201: 108939, 2024 Aug 13.
Article in English | MEDLINE | ID: mdl-38897450

ABSTRACT

The organization of semantic memory, including memory for word meanings, has long been a central question in cognitive science. Although there is general agreement that word meaning representations must make contact with sensory-motor and affective experiences in a non-arbitrary fashion, the nature of this relationship remains controversial. One prominent view proposes that word meanings are represented directly in terms of their experiential content (i.e., sensory-motor and affective representations). Opponents of this view argue that the representation of word meanings reflects primarily taxonomic structure, that is, their relationships to natural categories. In addition, the recent success of language models based on word co-occurrence (i.e., distributional) information in emulating human linguistic behavior has led to proposals that this kind of information may play an important role in the representation of lexical concepts. We used a semantic priming paradigm designed for representational similarity analysis (RSA) to quantitatively assess how well each of these theories explains the representational similarity pattern for a large set of words. Crucially, we used partial correlation RSA to account for intercorrelations between model predictions, which allowed us to assess, for the first time, the unique effect of each model. Semantic priming was driven primarily by experiential similarity between prime and target, with no evidence of an independent effect of distributional or taxonomic similarity. Furthermore, only the experiential models accounted for unique variance in priming after partialling out explicit similarity ratings. These results support experiential accounts of semantic representation and indicate that, despite their good performance at some linguistic tasks, the distributional models evaluated here do not encode the same kind of information used by the human semantic system.


Subject(s)
Semantics , Humans , Female , Male , Young Adult , Language , Adult , Models, Psychological , Reaction Time/physiology , Adolescent , Psycholinguistics
14.
Magn Reson Med ; 2024 Jun 18.
Article in English | MEDLINE | ID: mdl-38888143

ABSTRACT

PURPOSE: To investigate the impact of reduced k-space sampling on B 1 + $$ {\mathrm{B}}_1^{+} $$ mapping and the resulting impact on phase shimming and dynamic/universal parallel transmit (pTx) RF pulse design. METHODS: Channel-wise 3D B 1 + $$ {\mathrm{B}}_1^{+} $$ maps were measured at 7 T in 35 and 23 healthy subjects for the heart and prostate region, respectively. With these B 1 + $$ {\mathrm{B}}_1^{+} $$ maps, universal phase shims optimizing homogeneity and B 1 + $$ {\mathrm{B}}_1^{+} $$ efficiency were designed for heart and prostate imaging. In addition, universal 4kT-point pulses were designed for the heart. Subsequently, individual phase shims and individual 4kT-pulses were designed based on B 1 + $$ {\mathrm{B}}_1^{+} $$ maps with different acceleration factors and tested on the original maps. The performance of the pulses was compared by evaluating their coefficients of variation (CoV), B 1 + $$ {\mathrm{B}}_1^{+} $$ efficiencies and specific energy doses (SED). Furthermore, validation measurements were carried out for one heart and one prostate subject. RESULTS: For both organs, the universal phase shims showed significantly higher B 1 + $$ {\mathrm{B}}_1^{+} $$ efficiencies and lower CoVs compared to the vendor provided default shim, but could still be improved with individual phase shims based on accelerated B 1 + $$ {\mathrm{B}}_1^{+} $$ maps (acquisition time = 30 s). In the heart, the universal 4kT-pulse achieved significantly lower CoVs than tailored phase shims. Tailored 4kT-pulses based on accelerated B 1 + $$ {\mathrm{B}}_1^{+} $$ maps resulted in even further reduced CoVs or a 2.5-fold reduction in SED at the same CoVs as the universal 4kT-pulse. CONCLUSION: Accelerated B 1 + $$ {\mathrm{B}}_1^{+} $$ maps can be used for the design of tailored pTx pulses for prostate and cardiac imaging at 7 T, which further improve homogeneity, B 1 + $$ {\mathrm{B}}_1^{+} $$ efficiency, or SED compared to universal pulses.

15.
Sensors (Basel) ; 24(11)2024 May 29.
Article in English | MEDLINE | ID: mdl-38894303

ABSTRACT

The most critical aspect of panorama generation is maintaining local semantic consistency. Objects may be projected from different depths in the captured image. When warping the image to a unified canvas, pixels at the semantic boundaries of the different views are significantly misaligned. We propose two lightweight strategies to address this challenge efficiently. First, the original image is segmented as superpixels rather than regular grids to preserve the structure of each cell. We propose effective cost functions to generate the warp matrix for each superpixel. The warp matrix varies progressively for smooth projection, which contributes to a more faithful reconstruction of object structures. Second, to deal with artifacts introduced by stitching, we use a seam line method tailored to superpixels. The algorithm takes into account the feature similarity of neighborhood superpixels, including color difference, structure and entropy. We also consider the semantic information to avoid semantic misalignment. The optimal solution constrained by the cost functions is obtained under a graph model. The resulting stitched images exhibit improved naturalness. Extensive testing on common panorama stitching datasets is performed on the algorithm. Experimental results show that the proposed algorithm effectively mitigates artifacts, preserves the completeness of semantics and produces panoramic images with a subjective quality that is superior to that of alternative methods.

16.
Br J Dev Psychol ; 2024 Jun 10.
Article in English | MEDLINE | ID: mdl-38859629

ABSTRACT

Human visual memory capacity has a rapid developmental progression. Here we examine whether image semantics modulate this progression. We assessed the performance of children (6-14 years) and young adults (19-36 years) on a visual memory task using real-world (or meaningful) as well as abstract image sets, which were matched in low-level image attributes. For real images, we find comparable performance across the two age groups, consistent with previously reported results. However, for abstract images, we find a clear age-related difference indicating greater reliance of children's memory processes on semantics, suggesting that strategies for encoding abstract patterns keep improving even into late childhood. We complemented these studies with computational experiments designed to examine the role of increasing experience with real-world images on real and abstract image encoding, to examine whether the observed age-related differences, as well as the general privilege of real over abstract images, can emerge directly through experience with meaningful images. Our results provide support for this possibility and set the stage for a finer-grained investigation of the timeline along which children's memory capacity for abstract images reaches adult levels.

17.
Front Artif Intell ; 7: 1406773, 2024.
Article in English | MEDLINE | ID: mdl-38881954

ABSTRACT

The article addresses the accelerating human-machine interaction using the large language model (LLM). It goes beyond the traditional logical paradigms of explainable artificial intelligence (XAI) by considering poor-formalizable cognitive semantical interpretations of LLM. XAI is immersed in a hybrid space, where humans and machines have crucial distinctions during the digitisation of the interaction process. The author's convergent methodology ensures the conditions for making XAI purposeful and sustainable. This methodology is based on the inverse problem-solving method, cognitive modeling, genetic algorithm, neural network, causal loop dynamics, and eigenform realization. It has been shown that decision-makers need to create unique structural conditions for information processes, using LLM to accelerate the convergence of collective problem solving. The implementations have been carried out during the collective strategic planning in situational centers. The study is helpful for the advancement of explainable LLM in many branches of economy, science and technology.

18.
Cogn Sci ; 48(6): e13475, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38923016

ABSTRACT

A view that has been gaining prevalence over the past decade is that the human conceptual system is malleable, dynamic, context-dependent, and task-dependent, that is, flexible. Within the flexible conceptual representation framework, conceptual representations are constructed ad hoc, forming a different, idiosyncratic instantiation upon each occurrence. In this review, we scrutinize the neurocognitive literature to better understand the nature of this flexibility. First, we identify some key characteristics of these representations. Next, we consider how these flexible representations are constructed by addressing some of the open questions in this framework: We review the age-old question of how to reconcile flexibility with the apparent need for shareable stable definitions to anchor meaning and come to mutual understanding, as well as some newer questions we find critical, namely, the nature of relations among flexible representations, the role of feature saliency in activation, and the viability of all-or-none feature activations. We suggest replacing the debate about the existence of a definitional stable core that is obligatorily activated with a question of the degree and probability of activation of the information constituting a conceptual representation. We rely on published works to suggest that (1) prior featural salience matters, (2) feature activation may be graded, and (3) Bayesian updating of prior information according to current demands offers a viable account of how flexible representations are constructed. This proposal provides a theoretical mechanism for incorporating a changing momentary context into a constructed representation, while still preserving some of the concept's constituent meaning.


Subject(s)
Concept Formation , Humans , Cognition , Bayes Theorem , Comprehension
19.
Magn Reson Med ; 2024 Jun 27.
Article in English | MEDLINE | ID: mdl-38934380

ABSTRACT

PURPOSE: To acquire accurate volumetric multi-channel B 1 + $$ {\mathrm{B}}_1^{+} $$ maps in under 14 s whole-brain or 23 heartbeats whole-heart for parallel transmit (pTx) applications at 7 T. THEORY AND METHODS: We evaluate the combination of three recently proposed techniques. The acquisition of multi-channel transmit array B 1 + $$ {\mathrm{B}}_1^{+} $$ maps is accelerated using transmit low rank (TxLR) with absolute B 1 + $$ {\mathrm{B}}_1^{+} $$ mapping (Sandwich) acquired in a B 1 + $$ {\mathrm{B}}_1^{+} $$ time-interleaved acquisition of modes (B1TIAMO) fashion. Simulations using synthetic body images derived from Sim4Life were used to test the achievable acceleration for small scan matrices of 24 × 24. Next, we evaluated the method by retrospectively undersampling a fully sampled B 1 + $$ {\mathrm{B}}_1^{+} $$ library of nine subjects in the brain. Finally, Cartesian undersampled phantom and in vivo images were acquired in both the brain of three subjects (8Tx/32 receive [Rx]) and the heart of another three subjects (8Tx/8Rx) at 7 T. RESULTS: Simulation and in vivo results show that volumetric multi-channel B 1 + $$ {\mathrm{B}}_1^{+} $$ maps can be acquired using acceleration factors of 4 in the body, reducing the acquisition time to within 23 heartbeats, which was previously not possible. In silico heart simulations demonstrated a RMS error to the fully sampled native resolution ground truth of 4.2° when combined in first-order circularly polarized mode (mean flip angle 66°) at an acceleration factor of 4. The 14 s 3D B 1 + $$ {\mathrm{B}}_1^{+} $$ maps acquired in the brain have a RMS error of 1.9° to the fully sampled (mean flip angle 86°). CONCLUSION: The proposed method is demonstrated as a fast pTx calibration technique in the brain and a promising method for pTx calibration in the body.

20.
Cereb Cortex ; 34(6)2024 Jun 04.
Article in English | MEDLINE | ID: mdl-38863113

ABSTRACT

Neuropsychological and neuroimaging studies provide evidence for a degree of category-related organization of conceptual knowledge in the brain. Some of this evidence indicates that body part concepts are distinctly represented from other categories; yet, the neural correlates and mechanisms underlying these dissociations are unclear. We expand on the limited prior data by measuring functional magnetic resonance imaging responses induced by body part words and performing a series of analyses investigating the cortical representation of this semantic category. Across voxel-level contrasts, pattern classification, representational similarity analysis, and vertex-wise encoding analyses, we find converging evidence that the posterior middle temporal gyrus, the supramarginal gyrus, and the ventral premotor cortex in the left hemisphere play important roles in the preferential representation of this category compared to other concrete objects.


Subject(s)
Brain Mapping , Magnetic Resonance Imaging , Humans , Female , Male , Brain Mapping/methods , Adult , Young Adult , Concept Formation/physiology , Brain/physiology , Brain/diagnostic imaging , Semantics
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