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1.
Macromol Rapid Commun ; : e2400414, 2024 Jul 22.
Article in English | MEDLINE | ID: mdl-39038120

ABSTRACT

Carbon fiber (CF)-reinforced epoxy resin (EP) composites are lightweight materials with excellent comprehensive performance. However, the flammability of EP and the poor interfacial bonding between CF and EP are two key disadvantages that limit their further applications. Here, a kind of water-soluble lignin-based CF sizing agent (ELBEDK) is prepared through hydrophilic modification of enzymatic lignin, which can significantly enhance the interfacial interaction between CF and EP. Additionally, a highly efficient intumescent flame retardant (LMA) is prepared. The EP, enzymatic lignin, LMA and CF sized ELBEDK are compounded to obtain the fire-safety CF reinforced composites (SCF/FEP/L). The flame retardancy of SCF/FEP/L with 7% LMA (SCF/FEP7) reached V-0 rating. Moreover, SCF/FEP/L with 7% LMA and 15% lignin (SCF/FEP7/L15) present an limiting oxygen index (LOI)of 30.2% and V-0 of UL-94. Specifically, the total smoke production and the heat release rate are 47.8% and 46.81% lower than that of SCF/EP, respectively, indicating the improved smoke suppression and flame retardancy. The IFSS and flexural strength of SCF/FEP7/L15 are improved to be 59.4 MPa and 511.1 MPa, respectively. This study presents a simple approach to fabricate low-cost high performance lignin-based flame retardant CF/EP biocomposites with wide application potential.

2.
Environ Pollut ; 356: 124354, 2024 Jun 09.
Article in English | MEDLINE | ID: mdl-38862097

ABSTRACT

Recent advancements in particulate matter (PM) optical measurement technology have enhanced the characterization of particle size distributions (PSDs) across various temporal and spatial scales, offering a more detailed analysis than traditional PM mass concentration monitoring. This study employs field experiments, laboratory tests, and model simulations to evaluate the influence of physicochemical characteristics of particulate matter (PM) on the performance of a compact, multi-channel PM sizing sensor. The sensor is integrated within a mini air station (MAS) designed to detect particles across 52 channels. The field experiments highlighted the sensor's ability to track hygroscopicity parameter κ-values across particle sizes, noting an increasing trend with particle size. The sensor's capability in identifying the size and mass concentration of different PM types, including ammonium nitrate, sodium chloride, smoke, incense, and silica dust particles, was assessed through laboratory tests. Laboratory comparisons with the Aerodynamic Particle Sizer (APS) showed high consistency (R2 > 0.96) for various PM sources, supported by Kolmogorov-Smirnov tests confirming the sensor's capability to match APSsize distributions. Model simulations further elucidated the influence of particle refractive index and size distributions on sensor performance, leading to optimized calibrant selection and application-specific recommendations. These comprehensive evaluations underscore the critical interplay between the chemical composition and physical properties of PM, significantly advancing the application and reliability of optical PM sensors in environmental monitoring.

3.
Sensors (Basel) ; 24(12)2024 Jun 20.
Article in English | MEDLINE | ID: mdl-38931775

ABSTRACT

Operational amplifiers (Op-Amps) are critical to sensor systems because they enable precise, reliable, and flexible signal processing. Current automated Op-Amp generation methods suffer from extremely low efficiency because the time-consuming SPICE-in-the-loop sizing is normally involved as its inner loop. In this paper, we propose an efficiently automated Op-Amp generation tool using a hybrid sizing method, which combines the merits together from a deterministic optimization algorithm and differential evolution algorithm. Thus, it can not only quickly find a decent local optimum, but also eventually converge to a global optimum. This feature is well fit to be serving as an acute filter in the circuit structure evaluation flow to efficiently eliminate any undesirable circuit structures in advance of detailed sizing. Our experimental results demonstrate its superiority over traditional sizing approaches and show its efficacy in highly boosting the efficiency of automated Op-Amp structure generation.

4.
Heliyon ; 10(11): e31843, 2024 Jun 15.
Article in English | MEDLINE | ID: mdl-38873666

ABSTRACT

This paper presents the placement and sizing of energy hubs (EHs) in electricity, gas, and heating networks. EH is a coordinator framework for various power sources, storage devices, and responsive loads. For simultaneous modeling of economic, operation, reliability, and flexibility indices, the proposed scheme is expressed as a three-objective optimization in the form of Pareto optimization based on the sum of weighted functions. The objective functions of this problem respectively minimize the planning cost of EHs (equal to the total cost of construction of hubs and their expected operating cost), the expected energy loss of the mentioned networks, and the expected energy not-supplied (EENS) of these networks in the case of an N - 1 event. The problem is constrained by power flow equations and operation and reliability constraints of these network together with the EH planning and operation model, and flexibility constraints of the EHs. Then, to achieve unique optimal solution in the shortest possible time, a linear approximation model is extracted for the proposed scheme. Moreover, scenario-based stochastic programming (SBSP) is employed to model uncertainties of load, energy cost, renewable power, and accessibility of the mentioned network equipment. Finally, the obtained numerical results indicate the capability of the proposed scheme in enhancing the economic and flexibility situation of EHs and improving the reliability and operation status of energy networks along with achieving optimal planning and operation for EHs.

5.
Heliyon ; 10(11): e31208, 2024 Jun 15.
Article in English | MEDLINE | ID: mdl-38845973

ABSTRACT

This paper aims to enhance the design and operation of a Combined Cooling, Heating, and Power (CCHP) system utilizing a gas engine as the primary energy source for a residential building in China. An Energy, Exergy, Economic, and Environment (4E) analysis is employed to assess the system's performance and impact based on energy, exergy, economic, and environmental criteria. The effectiveness of the DNGO algorithm is evaluated on a case study site and compared with Northern Goshawk Optimization (NGO) and Genetic Algorithm (GA). The findings demonstrate that the DNGO algorithm identifies the optimal gas engine size of 130 kW. The algorithm's search capabilities are greatly enhanced by this unique blend, surpassing what traditional methods can offer. The DNGO algorithm brings several advantages, including unparalleled energy efficiency, reduced exergy destruction, and a substantial decrease in C O 2 emissions. This not only supports environmental sustainability but also aligns with global standards. Economically, the algorithm enhances the performance of the CCHP system, evident through a reduced payback period and increased annual profit. Additionally, the algorithm's rapid convergence rate allows it to reach the optimal solution faster than its counterparts, making it advantageous for time-sensitive applications. Incorporating innovative methods like chaos theory, the DNGO algorithm effectively avoids local optima, enabling a broader search for the best solution. The utilization of Lévy flight further enhances the algorithm's ability to escape local optima and navigate the search space more efficiently. Additionally, swarm intelligence is employed to simulate the collective behavior of decentralized systems, aiding in problem-solving. This research represents a significant advancement in optimization techniques for CCHP systems and offers a fresh perspective to the field of swarm-based optimization algorithms.

6.
ACS Appl Mater Interfaces ; 16(25): 31877-31894, 2024 Jun 26.
Article in English | MEDLINE | ID: mdl-38868858

ABSTRACT

Interfacial failure in carbon fiber-reinforced epoxy (CFRE) laminates is a prominent mode of failure, attracting significant research attention. The large surface-energy mismatch between carbon fiber (CF) and epoxy results in a weaker interface. This study presents a facile yet effective method for enhancing the interfacial adhesion between CF and epoxy with self-healable interfaces. Two variants of a designer sizing agent, poly(ether imide) (PEI), were synthesized, one without a self-healing property termed BO, and the second one by incorporating disulfide metathesis in one of its monomers that renders self-healing properties at the interface-mediated by network reconfiguration, termed BA. 0.25 wt % of CF was found to be the optimum amount of BO and BA sizing agents. The surface free energy of CF drastically increased and became quite close to the surface energy of epoxy after the deposition of both sizing agents and the higher surface roughness. The improved surface wettability, presence of functional groups, and mechanical interlocking worked in tandem to strengthen the interface. The interlaminar shear strength (ILSS) and flexural strength (FS) of CFRE laminate sized with BO consequently increased by 35% and 22% and of CFRE laminate sized with BA increased by 26% and 19%, respectively. Fractography analysis revealed outstanding bonding between epoxy and PEI-CF, indicating that matrix fracture is the predominant mode of failure. The self-healable interfaces due to the preinstalled disulfide metathesis in the sizing agent resulted in 51% self-healing efficiency in ILSS for BA-sized CFRE laminate. Interestingly, the functional properties, deicing, and EMI shielding effectiveness were not compromised by modification of the interface with this designer sizing agent. This study opens new avenues for interfacial modification to improve the mechanical properties while retaining the key functional properties of the laminates.

7.
Int J Biol Macromol ; 271(Pt 2): 132716, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38815941

ABSTRACT

Nanoparticle-containing sizing agents are essential for the overall performance of high-quality carbon fiber (CF) composites. However, the uneven dispersion of nanoparticles often leads to agglomeration on the surface of CF after sizing, consequently diminishing the material properties. In this study, the properties of cellulose nanofibers (CNFs) that can respond to magnetic and electric fields were utilized to achieve three-dimensional to one-dimensional orientations in CFs containing sizing agents. Cobalt ferrite (CoFe2O4) was utilized to enhance the response of CNFs to a magnetic field, and subsequently, it was combined with an electric field to attain a higher degree of orientation. The occurrence of nanoparticle agglomeration is diminished on CF surface, while establishing a structured network. The flexural strength and thermal conductivity of CF composites treated with CoFe2O4 self-assembled CNF sizing agent exhibit an increase of 54.23 % and 57.5 %, respectively, compared to those of desized CF composites, when subjected to magnetic and electric fields. Consequently, the approach can depolymerize the nano-fillers within the sizing agent and orient it into the carbon fiber under the influence of magnetic and electric fields, effectively improving the mechanical properties and thermal conductivity of the composite material.


Subject(s)
Carbon Fiber , Cellulose , Magnetic Fields , Nanofibers , Nanofibers/chemistry , Cellulose/chemistry , Carbon Fiber/chemistry , Ferric Compounds/chemistry , Cobalt/chemistry , Electricity , Thermal Conductivity , Nanocomposites/chemistry
9.
Int J Audiol ; : 1-10, 2024 May 28.
Article in English | MEDLINE | ID: mdl-38804563

ABSTRACT

OBJECTIVE: Evaluate the ability of an extended version of the 3 MTM Eargage to estimate the earcanal size and assess the likelihood that a particular earplug can fit an individual's earcanal, ultimately serving as a tool for selecting earplugs in the field. DESIGN: Earcanal morphology, assessed through earcanal earmolds scans, is compared to earcanal size assessed with the extended eargage (EE) via box plots and Pearson linear correlations coefficients. Relations between attenuation measured on participants (for 6 different earplugs) and their earcanal size assessed with the EE are established via comparison tests. STUDY SAMPLE: 121 participants exposed to occupational noise (103 men, 18 women, mean age 47 years). RESULTS: The earcanal size assessed with the EE allows for estimating the area of the earcanal's first bend cross-section (correlation coefficient  r = 0.533, p < 0.001). Extremely large earcanals (12.7% of earcanals in our sample) lead to significantly lower earplug attenuation (potentially inadequate) than smaller earcanals. CONCLUSIONS: The EE is a simple and inexpensive tool easily deployable in the field to assist earplugs selection. When extended with sizes larger than the maximum size of the commercial tool, it allows for detecting individuals with extremely large earcanals who are most likely to be under-protected.

10.
J Funct Biomater ; 15(5)2024 May 14.
Article in English | MEDLINE | ID: mdl-38786637

ABSTRACT

Treating severe dermal disruptions often presents significant challenges. Recent advancements have explored biological cell sprays as a promising treatment, but their success hinges on efficient cell delivery and complete wound coverage. This requires a good spray distribution with a small droplet size, high particle number, and ample surface coverage. The type of nozzle used with the spray device can impact these parameters. To evaluate the influence of different nozzles on spray characteristics, we compared air-assisted and unassisted nozzles. The unassisted nozzle displayed small particle size, high particle number, good overall coverage, high cell viability, preserved cell metabolic activity, and low cytotoxicity. Air-assisted nozzles did not perform well regarding cell viability and metabolic activity. Flow visualization analysis comparing two different unassisted nozzles using high-speed imaging (100 kHz frame rate) revealed a tulip-shaped spray pattern, indicating optimal spray distribution. High-speed imaging showed differences between the unassisted nozzles. One unassisted nozzle displayed a bi-modal distribution of the droplet diameter while the other unassisted nozzle displayed a mono-modal distribution. These findings demonstrate the critical role of nozzle selection in successful cell delivery. A high-quality, certified nozzle manufactured for human application omits the need for an air-assisted nozzle and provides a simple system to use with similar or better performance characteristics than those of an air-assisted system.

11.
Methods Mol Biol ; 2804: 53-64, 2024.
Article in English | MEDLINE | ID: mdl-38753139

ABSTRACT

The µLAS technology enables in-line DNA concentration and separation in a microchannel. Here, we describe its operation to analyze the size profile of cell-free DNA (cfDNA) extracted from blood plasma. Operated on commercial systems for capillary electrophoresis, we provide the size distribution of healthy individuals or patients using an input of 10 µL.


Subject(s)
Cell-Free Nucleic Acids , Electrophoresis, Capillary , Cell-Free Nucleic Acids/blood , Cell-Free Nucleic Acids/isolation & purification , Cell-Free Nucleic Acids/genetics , Humans , Electrophoresis, Capillary/methods
12.
Cureus ; 16(3): e55735, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38586638

ABSTRACT

Background and objective Sizing on digital films is important for implants and planning deformity correction. CT is the most accurate digital measurement method. We use a 1-inch ball bearing (cost: $1) to size our long-leg standing films (LLSFs) when planning deformity correction. In this study, we aimed to assess the accuracy of digital measurements calibrated by this method. Methods We conducted An IRB-approved study involving 25 patients having both an LLSF with a 1-inch ball bearing taped to the inner mid-thigh and a CT scanogram. The longest distance in the axial cut of the bilateral ankle, knee, and femoral heads of the CT images were compared to the same anatomic locations on LLSFs calibrated with the ball bearing using the online digital planning software DetroitBonesetter (DBS) and measurements from our Picture Archiving Communication Software (PACS). Five observers performed each measurement. Results The average measurement differences between the gold standard CT scan and LLSFs calibrated with DBS were as follows: 0.110 ± 0.432 mm (femoral head); 2.173 ± 0.0619 mm (knee); and 3.671 ± 0.30 mm (ankle). In PACS, they were as follows: 5.470 ± 0.381 mm (femoral head); 6.248 ± 0.712 mm (knee); and 1.806 ± 0.548 mm (ankle). The intraclass correlation coefficient for 600 measurements by five observers was 0.972. Conclusions The $1 ball-bearing sizing on DBS using LLSFs provides accuracy to <1 mm for the femoral head, 2 mm at the knee, and 3.7 mm at the ankle. It was significantly better than the PACS system for both the femoral head and knee (<0.001), while PACS was better at the ankle (<0.001).

13.
Beilstein J Nanotechnol ; 15: 317-332, 2024.
Article in English | MEDLINE | ID: mdl-38590429

ABSTRACT

Titanium dioxide (TiO2) pigment is a non-toxic, particulate material in widespread use and found in everyone's daily life. The particle size of the anatase or rutile crystals are optimised to produce a pigment that provides the best possible whiteness and opacity. The average particle size is intentionally much larger than the 100 nm boundary of the EU nanomaterial definition, but the TiO2 pigment manufacturing processes results in a finite nanoscale content fraction. This optically inefficient nanoscale fraction needs to be quantified in line with EU regulations. In this paper, we describe the measurement procedures used for product quality assurance by three TiO2 manufacturing companies and present number-based primary particle size distributions (PSDs) obtained in a round-robin study performed on five anatase pigments fabricated by means of sulfate processes in different plants and commonly used worldwide in food, feed, pharmaceutical and cosmetic applications. The PSDs measured by the three titanium dioxide manufacturers based on electron micrographs are in excellent agreement with one another but differ significantly from those published elsewhere. Importantly, in some cases, the PSDs result in a different regulatory classification for some of the samples tested. The electron microscopy results published here are supported by results from other complementary methods including surface area measurements. It is the intention of this publication to contribute to an ongoing discussion on size measurements of TiO2 pigments and other particulate materials and advance the development of widely acceptable, precise, and reproducible measurement protocols for measuring the number-based PSDs of particulate products in the size range of TiO2 pigments.

14.
Heliyon ; 10(7): e26961, 2024 Apr 15.
Article in English | MEDLINE | ID: mdl-38590876

ABSTRACT

In this paper, the planning of a hybrid system of wind turbine units, photovoltaic panels, and battery storage is presented by taking into account the limitation of the storage degradation. The scheme minimizes the construction and maintenance cost of power sources and storage equipment. The constraints of the problem include the operating model of the mentioned elements, the limitation of the number of the mentioned elements, the limitation of the storage degradation, and the power balance in the hybrid system. This scheme is subject to uncertainties of the demand and output power generation of wind turbines and photovoltaics, which are modeled using a scenario-based stochastic optimization. The problem has a mixed-integer non-linear structure, and the paper adopts the firefly algorithm to solve the problem. The contributions of the paper include considering the degradation model of the battery, presenting a stochastic modelling for planning the islanded system, and taking into account the uncertainties of load and renewable power. Finally, based on the numerical results, a low planning cost is obtained for the hybrid system in the case of using renewable resources. Batteries are capable of providing flexibility for the hybrid system so that they can cover oscillations of renewable power with respect to the load. The firefly algorithm can find a reliable optimal solution. Stochastic modeling raises the planning cost of the islanded system in comparison to the deterministic model, but it yields a more reliable solution. The battery degradation model incurs no additional costs in system planning, although it offers a far more precise representation of the battery's behavior.

15.
Materials (Basel) ; 17(7)2024 Mar 28.
Article in English | MEDLINE | ID: mdl-38612072

ABSTRACT

Semi-aromatic poly (hexamethylene terephthalamide) (PA6T) oligomer (prePA6T) ultrafine powder, with a diameter of <5 µm, was prepared as an emulsion sizing agent to improve the impregnation performance of CF/PA6T composites. The prePA6T hyperfine powder was acquired via the dissolution and precipitation "phase conversion" method, and the prePA6T emulsion sizing agent was acquired to continuously coat the CF bundle. The sized CF unidirectional tape was knitted into a fabric using the plain weave method, while the CF/PA6T laminated composites were obtained by laminating the plain weave fabrics with PA6T films. The interfacial shear strength (IFSS), tensile strength (TS), and interlaminar shear strength (ILSS) of prePA6T-modified CF/PA6T composites improved by 54.9%, 125.3%, and 120.9%, respectively. Compared with the commercial polyamide sizing agent product PA845H, the prePA6T sizing agent showed better interfacial properties at elevated temperatures, especially no TS loss at 75 °C. The SEM observations also indicated that the prePA6T emulsion has an excellent impregnation effect on CF, and the fracture mechanism shifted from adhesive failure mode to cohesive failure mode. In summary, a facile, heat-resistant, undamaged-to-fiber environmental coating process is proposed to continuously manufacture high-performance thermoplastic composites, which is quite promising in mass production.

16.
Clin Ophthalmol ; 18: 1033-1043, 2024.
Article in English | MEDLINE | ID: mdl-38601168

ABSTRACT

More than 2 million implantable collamer lenses (ICLs) have been implanted worldwide. With a central port to improve aqueous flow through the ICL, the latest iteration of this phakic intraocular lens (pIOL) has been shown to have stable outcomes with very low rates of adverse events. However, correct planning and ICL size selection continue to be important to achieve an optimal vault. Shallow or excessive vaults are not complications in and of themselves but may increase the risk of complications. Historically, surgeons have relied on measurements of anterior chamber depth (ACD) and manual, caliper-measured white-to-white (WTW) distance to select the ICL size. New diagnostic and imaging technologies such as optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM) provide additional opportunities for visualization and measurement of the intraocular dimensions involved in phakic intraocular lens implantation, including sulcus-to-sulcus (STS) and angle-to-angle (ATA) diameters. This paper reviews various approaches to ICL planning and sizing that have been published in the peer-reviewed literature, all of which produce acceptable results for predicting vault and size selection. Surgeons may also want to identify a methodology for patient evaluation and ICL size selection that best aligns with their personal preferences, diagnostic technology, and familiarity with analytical optimization tools.


Phakic intraocular lenses (pIOLs) are one method for correcting nearsightedness, with or without astigmatism. This category of refractive surgery has been growing rapidly in the US and around the world. Implantation of the implantable collamer lens (ICL), one type of pIOL, is safe and effective, with stable outcomes and low adverse event rates. When complications do occur, they are typically associated with an inappropriate vault, or distance between the implant and the natural lens. Preoperative planning and accurate ICL sizing are required to achieve an optimal vault and varies, depending on the diagnostic technology available to the surgeon. This paper reviews the current approaches to ICL planning and sizing in order to provide guidance to surgeons implanting this pIOL.

17.
Work ; 2024 Apr 04.
Article in English | MEDLINE | ID: mdl-38640184

ABSTRACT

BACKGROUND: Textile-sizing mill workers are exposed to various hazards in the sizing units during their working hours and are at risk of acquiring lung impairments due to the usage of sizing chemicals in the sizing process. OBJECTIVE: The main aim of this study is to assess the influence of cotton dust and sizing agents on lung function and breathing difficulties among Indian textile sizing mill workers. METHODS: This cross-sectional study was carried out at a textile-sizing mill from August 2022 to September 2022. A modified questionnaire based American Thoracic Society's standard was used to assess respiratory symptoms among sizing mill workers and the pulmonary function test was conducted Spirometry. The chi-square test was used to find the difference between respiratory symptoms and the t-test was used to find the difference between spirometric parameters. RESULTS: Textile sizing mill workers showed significant (P <  0.0001) decline in peak expiratory flow rate, forced vital capacity (FVC), ratio of FEV1 and forced vital capacity, and forced expiratory volume in 1 s (FEV1). There was an association between symptoms and duration of exposure to pulmonary abnormality. Sizing mill workers showed a significant decline in lung functions and an increase in pulmonary symptoms. As the service duration of exposure in terms of years increased, respiratory symptoms increased and spirometric abnormality also increased. CONCLUSION: This study confirms that sizing agents such as polyvinyl alcohol (PVA), emulsifier, wax, carboxymethyl cellulose (CMC), and starch used in sizing mills are also responsible for respiratory illness and lung impairment among textile workers.

18.
Sports (Basel) ; 12(4)2024 Mar 26.
Article in English | MEDLINE | ID: mdl-38668560

ABSTRACT

The scope of this pilot study was to assess the feasibility of using the laser imaging detection and ranging (LiDAR) technology for contactless 3D body scanning of sports athletes and deriving anthropometric measurements of the lower limbs using available software. An Apple iPad Pro 3rd Generation with embedded LiDAR technology in combination with the iOS application Polycam were used. The effects of stance width, clothing, background, lighting, scan distance and measurement speed were initially assessed by scanning the lower limbs of one test person multiple times. Following these tests, the lower limbs of 12 male and 10 female participants were scanned. The resulting scans of the lower limbs were complete for half of the participants and categorized as good in quality, while the other scans were either distorted or presented missing data around the shank and/or the thigh. Bland-Altman plots between the LiDAR-based and manual anthropometric measures showed good agreement, with the coefficient of determination from correlation analysis being R2 = 0.901 for thigh length and R2 = 0.830 for shank length, respectively. The outcome of this pilot study is considered promising, and a further refinement of the proposed scanning protocol and advancement of available software for 3D reconstruction are recommended to exploit the full potential of the LiDAR technology for the contactless anthropometric assessment of athletes.

19.
Int J Pharm ; 656: 124097, 2024 May 10.
Article in English | MEDLINE | ID: mdl-38609058

ABSTRACT

The size and concentration are critical for the diagnostic and therapeutic applications of nanomaterials but the accurate measurement remains challenging. Nanoparticle tracking analysis (NTA) is widely used for size and concentration determination. However, highly repeatable standard operating procedures (SOPs) are absent. We adopted the "search-evaluate-test" strategy to standardize the measurement by searching the critical parameters. The particles per frame are linearly proportional to the sample concentration and the measured results are more accurate and repeatable when the concentration is 108-109 particles/ml. The optimal detection threshold is around 5. The optimal camera level is such that it allows clear observation of particles without diffractive rings and overexposure. The optimal speed is ≤ 50 in AU and âˆ¼ 10 µl/min in flow rate. We then evaluated the protocol using polydisperse polystyrene particles and we found that NTA could discriminate particles in bimodal mixtures with high size resolution but the performance on multimodal mixtures is not as good as that of resistive pulse sensing (RPS). We further analyzed the polystyrene particles, SiO2 particles, and biological samples by NTA following the SOPs. The size and concentration measured by NTA differentially varies to those determined by RPS and transmission electron microscopy.


Subject(s)
Nanoparticles , Particle Size , Polystyrenes , Silicon Dioxide , Nanoparticles/chemistry , Nanoparticles/analysis , Polystyrenes/chemistry , Silicon Dioxide/chemistry , Gold/chemistry , Microscopy, Electron, Transmission , Nanostructures/chemistry , Animals
20.
J Arthroplasty ; 2024 Apr 09.
Article in English | MEDLINE | ID: mdl-38599527

ABSTRACT

BACKGROUND: Anatomic referencing in total knee arthroplasty places the femoral component flush to the anterior cortex while maintaining posterior condylar offset (PCO). The intent of this study was to evaluate how component position influences the femoral component size. METHODS: Digital surface models were created using 446 femora from an established computed tomography database. Virtual bone resections, component sizing, and component placement were performed assuming neutral (0°) flexion and neutral (3°) rotation relative to the posterior condyles. The appropriately sized femoral component, which had 2 mm of incremental size, was placed flush with the anterior cortex for optimal restoration of the PCO. Sizing and placement were repeated using 3 and 6° flexion and 0, 5, and 7° external rotation (ER). RESULTS: At 0° flexion, decreasing ER from 3 to 0° resulted in an average decreased anterior-posterior height (APH) of 1.9 mm, corresponding to a component size decrease of 1 for 88% of patients. At 7° ER, component size increased by an average of 2.5 mm, corresponding to a size increase for 80% of patients. Flexing the femoral component to 3° with ER at 3° resulted in a decrease in APH of 2.2 mm (1 size decrease in 93% of patients). At 3° flexion and 3° ER, 86% had the same component size as at 0° flexion and 0° ER. Increasing ER at 3° flexion increased APH by 1.2 mm at 5° and 3.1 mm at 7° on average, relative to 3° ER. Increasing flexion from 3 to 6° extended this effect. CONCLUSIONS: Flexion decreases the APH when the ER is held constant. The ER of the femoral component increases the APH across all tested flexion angles, causing an increase in the ideal femoral component size to maintain PCO. With anatomic referencing, alterations in femoral component positioning and subsequent changes in component size can be accounted for.

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