Radiologic Findings of Multiple Myeloma with Gastric Involvement: A Case Report

We report a case of multiple myeloma with gastric involvement occurring in a patient who underwent an upper gastrointestinal series (UGIS), CT and MRI. UGIS depicted a luminal protruding mass, while contrast-enhanced CT demonstrated marked thickening of the gastric wall, with subtle contrast enhancement. At T1- and T2-weighted MR imaging, the mass showed iso- and intermediate signal intensity, respectively. After the administration of contrast material, subtle homogeneous enhancement was apparent.

Gastric Neuroendocrine Carcinoma Presenting as a Wandering Exophytic Mass: A Case Report

We describe a case of poorly differentiated gastric neuroendocrine carcinoma presenting as a wandering exophytic mass. CT imaging revealed a 14.5x10.0x8.0 cm, lobulated, solid mass with a multifocal necrotic portion at the right of the peritoneal cavity. It was attached to the antrum of the stomach by a broad stalk, and shown by MR imaging to be well-defined, lobulated and solid, with a multifocal necrotic portion, and at the left of the peritoneal cavity. Isointensity was apparent at T1-weighted imaging, and slightly hyperintensity at T2-weighted imaging, and after gadolinium injection, enhancement was stronger than at precontrast imaging.

Sarcomatoid Carcinoma of the Stomach: Report of Three Cases

Sarcomatoid carcinoma is a rare neoplasm of epithelial origin but consists partly of variable differentiated tumor cells of mesenchymal origin. Accurate diagnosis, including differentiation from adenocarcinoma or gastrointestinal stromal tumor, is difficult. We experienced three cases of sarcomatoid carcinoma of the stomach, and describe the radiological and pathologic findings. One case involved a polypoid mass in the antrum, another a mass with a large ulcer mimicking a Bormann type-II adenocarcinoma in the body, while in the third case, an intraluminal bulky mass arising from the cardia of the stomach was present. This was not differentiated from cancer or stromal tumor.

Cystic Lesions in the Stomach

Cystic lesions of the stomach are rare and usually detected incidentally during surgery or autopsy. Amongseven cases of cystic masses, duplication cysts accounted for four, retension cysts of ectopic pancreas for two,and cystic lymphangioma remaining one. In the upper gastrointestinal series, all were submucosally, whileendoscopic ultrasonography showed that the location of cystic masses was also submucosal. Except for two cases ofduplication cyst and cystic lymphangioma which were thin-walled, lesions were well-defined and showed lowattenuation. In addition, abdominal CT scanning showed two cases of retension cyst of ectopic pancreas.

Usefulness of Additional Prone pad compression Study in Upper Gastrointestinal Series for Detecting EarlyGastric Cancer

PURPOSE: To evaluate the usefulness of prone pad study in upper gastrointestinal series(UGIS) for thedetection of early gastric cancer(EGC). MATERIALS AND METHODS: During an eight-month period, 88 of 170 patientswho underwent gastrectomy due to EGC were also the subjects of prone pad study as well as double contrast(n=92),mucosal relief(n=76), or compression(n=91) studies. The EGCs were single in 84 patients and double in four. Wecompared prone pad study with the three other techniques for detecting a tumor and depicting the surroundingmucosal changes. Lesional conspicuity was rated 'complete', 'incomplete','suspicious'. or 'undetected'. Thedepiction of surrounding mucosal change was rated 'excellent', 'good', 'fair', or 'poor'. RESULTS: Mean tumorsize was 3.2cm, with a range of 0.3-9cm. Tumors were located in the antrum(n=55), angle(n=13), lower or midbody(n=16), or the sign body and cardia(n=5). Among the 92 EGCs evaluated, UGIS missed the lesion in threecases(sensitivity, 97%). The rates of 'complete' lesional conspicuity were 49% inn prone pad, 29% in compression,20% in double contrast, and 9% in mucosal relief. The rates of excellent' in depicting surrounding mucosal changewere 45% in prone pad, 11% in double contrast, 9% in mucosal relief, and 9% in compression. The tumor wasdemonstrated only in prone pad study in five(5%) of the 92 EGCs. CONCLUSION: prone pad study during UGIS improvesboth the detection rate of EGC and the depiction of mucosal change around the tumor.

Comparison of Radiologic and Pathologic Findings of Gastric MALToma

PURPOSE: To evaluate the radiologic findings of gastric MALToma, and to correlate these with its pathologic findings. MATERIALS AND METHODS: We retrospectively reviewed the pathologic slides of gastrectomy and gastroscopic biopsy specimens obtained between 1982 and 1996 and collected nine cases of gastric MALToma. Eight of these had been surgically confirmed, and one had been diagnosed by gastroscopic biopsy. A gastrointestinal series comprised eight cases ; five involved sonography and five, CT. RESULTS: The lesions were located at the body in five cases, at the antrum in one, and at the body and antrum in three cases. Pathologic diagnosis was low grade MALToma in four cases, and mixed high and low grade MALToma in five cases. Initial radiologic diagnosis was gastric lymphoma in four cases, early gastric carcinoma in three, and advanced gastric carcinoma in two cases. On retrospective analysis, radiologic diagnosis was changed to lymphoma in both cases initially diagnosed as advanced gastric carcinomas. One case showed marked thickening of the gastric wall, with poor enhancement on CT, and the other case showed a very small and shallow ulcer in comparison to diffuse infiltration of tumor in the upper gastrointestinal series. The final radiologic diagnosis was gastric lymphoma in six cases, and early gastric carcinoma in three. Radiologic findings of gastric MALToma were EGC II c-like lesion in three cases, marked gastric wall thickening in two, multiple discrete lesions in two, hyperugosity of gastric folds with discrete lesions in one, and diffuse infiltrative lesion with small ulcer in one case. The pathologic diagnosis of gastric MALToma was made by the presence of lymphoepithelial lesions, centrocyte-like cells, reactive follicles, plasma cell infiltration, and follicular colonization. There were no significant correlations between radiologic findings and pathologic results such as depth of tumor invasion, low grade MALToma or mixed high and low grade MALToma. CONCLUSION: There are no specific radiologic characteristics of gastric MALToma, but a gastric MALToma might show the radiologic findings of gastric lymphoma. Further radiologic evaluations of many cases of gastric MALTomas are needed in the future.