ABSTRACT
Objective: To evaluate the role of narrow band imaging (NBI) endoscopy in the diagnosis of laryngeal lesions. Methods: A total of 136 patients with laryngeal lesions were examined by NBI and white light (WLI) endoscopy from July 2016 to May 2017. Sensitivity, specificity, accuracy, and positive predictive value (PPV) and negative predictive value (NPV) of NBI and WLI were calculated. SPSS 20.0 software was used to analyze the data. Results: Compared to WLI, NBI showed higher sensitivity (94.9% vs 83.3%), specificity (95.6% vs 84.4%), PPV (94.9% vs 82.3%), and NPV (95.6% vs 85.4%). There was high consistency of the results etween NBI and pathology (kappa=0.904, P<0.01). However, consistency of the findings between WLI and pathology was relatively weak (kappa=0.677, P<0.01). NBI showed the higher accuracy in diagnoses of both benign lesions (especially for premalignant lesions, P<0.01) and malignant lesions (especially for high-grade intraepithelial neoplasia, P<0.05) than WLI. NBI findings correlated with the pathological results (r=0.739, P<0.01). Conclusions: NBI demonstrates higher accuracy in the detection of premalignant and malignant lesions of the larynx.
Subject(s)
Endoscopy/methods , Laryngeal Neoplasms/diagnostic imaging , Narrow Band Imaging/methods , Precancerous Conditions/diagnostic imaging , Humans , Laryngeal Neoplasms/pathology , Larynx/diagnostic imaging , Larynx/pathology , Light , Precancerous Conditions/pathology , Predictive Value of Tests , Prospective Studies , Sensitivity and SpecificityABSTRACT
Objective@#To evaluate the role of narrow band imaging (NBI) endoscopy in the diagnosis of laryngeal lesions.@*Methods@#A total of 136 patients with laryngeal lesions were examined by NBI and white light (WLI) endoscopy from July 2016 to May 2017. Sensitivity, specificity, accuracy, and positive predictive value (PPV) and negative predictive value (NPV) of NBI and WLI were calculated. SPSS 20.0 software was used to analyze the data.@*Results@#Compared to WLI, NBI showed higher sensitivity (94.9% vs 83.3%), specificity (95.6% vs 84.4%), PPV (94.9% vs 82.3%), and NPV (95.6% vs 85.4%). There was high consistency of the results etween NBI and pathology (kappa=0.904, P<0.01). However, consistency of the findings between WLI and pathology was relatively weak (kappa=0.677, P<0.01). NBI showed the higher accuracy in diagnoses of both benign lesions (especially for premalignant lesions, P<0.01) and malignant lesions (especially for high-grade intraepithelial neoplasia, P<0.05) than WLI. NBI findings correlated with the pathological results (r=0.739, P<0.01).@*Conclusions@#NBI demonstrates higher accuracy in the detection of premalignant and malignant lesions of the larynx.