Romantic relationship dissolutions are significantly associated with posttraumatic stress symptoms as compared to a DSM-5 Criterion A event: a case-case-control comparison.

Background: Non-marital romantic relationship dissolutions (RRDs) are common among emerging adult students (EAS) and may result in severe distress and suicidality. However, studies on RRDs in youth are limited to mental health sequelae of depression and prolonged grief. Little is known about the association between RRDs and posttraumatic stress symptoms (PTSS), and how this compares to posttraumatic stress symptoms following a traumatogenic event.Objective: We aimed to determine the association between RRDs and PTSS in an EAS sample; and how this compared to the association between posttraumatic stress symptoms and a Diagnostic and Statistical Manual 5th edition (DSM-5) traumatic event.Method: University students (N = 2,022; female = 71.1%; 18-25 years) completed a demographic and relationship questionnaire, the Life Events Checklist, the Adverse Childhood Experiences questionnaire, and the Posttraumatic Stress Checklist (PCL). We compared EAS with an RRD (n = 886) or a DSM-5 criterion A traumatic event (n = 592) against a control group (n = 544) exposed to a non-traumatic stressful life event. Utilising ANOVAs and Pearson's correlations we determined demographic and clinical variables associated with PTSS. ANCOVA and stepwise hierarchical regression analyses were used to determine between-group differences in PTSS.Results: Total trauma exposure and adverse childhood experiences, sex, monthly income, sexual orientation, and attachment style were significantly associated with PTSS. The RRD group had significantly higher PCL scores compared to the DSM and control groups. The mean PCL scores for both the RRD and DSM groups were above the cut-off score of 33, consistent with a probable posttraumatic stress disorder diagnosis. Significantly more RRD participants (72.9%) scored above the cut-off score of 33 than DSM-5 Trauma Group participants (55.4%).Conclusion: An RRD is a potentially traumatic event and is significantly associated with PTSS, similar to a posttraumatic stress disorder diagnosis.

Students may experience non-marital romantic relationship breakups as very painful, with various negative psychological, physical, and academic consequences. However, their painful experiences are often trivialised as something to 'just get over' and not acknowledged as potentially traumatic. Yet, using an attachment theory framework, breakups can be reconceptualised as subjectively traumatic.We explored the differences in posttraumatic stress symptoms of students who experienced a breakup, a traumatic event (as defined in psychiatry), and other non-traumatic life events. Students who experienced a breakup reported significantly highly posttraumatic stress symptoms.Acknowledging students' pain following a self-defined traumatic breakup can increase help-seeking behaviour and reduce the risk of intergenerational attachment trauma. Our findings warrant further research of breakups as potentially traumatogenic events.

Effectiveness of abbreviated trauma-focused cognitive behavioural therapy for South African adolescents: a randomized controlled trial.

Background: In low- and middle- income countries (LMICs) trauma exposure among youth is high, but mental health services are critically under-resourced. In such contexts, abbreviated trauma treatments are needed.Objective: To evaluate the efficacy of an abbreviated eight-session version of Trauma-Focused Cognitive Behavioural Therapy (TF-CBT) for improving posttraumatic stress disorder (PTSD) and depression symptoms in a sample of South African adolescents.Method: 75 trauma-exposed adolescents (21 males, 54 females; mean age = 14.92, range = 11-19) with posttraumatic stress disorder (PTSD) symptoms were randomly assigned to eight sessions of TF-CBT or to usual services. At baseline, post-treatment and three-month follow-up, participants completed the Child PTSD Symptom Scale for DSM 5 (CPSS-5) and the Beck Depression Inventory II (BDI-II). The trial is registered on the Pan African Trial Registry (PACTR202011506380839).6.Results: 95% of TF-CBT participants completed treatment while only 47% of TAU participants accessed treatment. Intention-to-treat analyses found that the TF-CBT group had a significantly greater reduction in CPSS-5 PTSD symptom severity at post-treatment (Cohen's d = 0. 60, p < .01) and three-month follow-up (Cohen's d = 0.62, p < . 01), and a greater reduction in the proportion of participants meeting the CPSS-5 clinical cut-off for PTSD at both time points (p = .02 and p = .03, respectively). There was also a significantly greater reduction in depression symptom severity in the TF-CBT group at post-treatment (Cohen's d = 0.51, p = .03) and three-month follow-up (Cohen's d = 0.41, p = .05), and a greater reduction in the proportion of TF-CBT participants meeting the BDI clinical cut-off for depression at both time points (p = .02 and p = .03, respectively).Conclusion: The findings provide preliminary evidence of the efficacy of an abbreviated eight-session version of TF-CBT for reducing PTSD and depression symptoms in a LMIC sample of adolescents with multiple trauma exposure.

Trauma-Focused Cognitive Behavioural Therapy (TF-CBT) is one of the leading evidence-based treatments for child and adolescent posttraumatic stress, but an abbreviated version has not been evaluated in low- and middle-income countries (LMICs).At post-treatment and three-month follow-up, eight sessions of TF-CBT were more effective than treatment-as-usual in reducing posttraumatic stress and depression symptoms in an LMIC sample of South African adolescents exposed to multiple traumas.Effect sizes were similar to those reported for standard length TF-CBT, indicating that abbreviated TF-CBT may be a suitable option for resource-constrained child and adolescent mental health services in LMICs.

Adapting Attachment and Biobehavioral Catch-up for infants and young children with intellectual disabilities and developmental delays in South Africa: Reflections and recommendations from local stakeholders.

Attachment and Biobehavioral Catch-up (ABC) is an intervention targeted at enhancing the socioemotional and regulatory functioning of at-risk infants. However, to use the ABC for infants/toddlers with intellectual disabilities/developmental delays (ID/DD) and in novel cultural contexts, such as South Africa, adaptations may be required. This study aimed, therefore, to explore the opinions of clinical experts and perceptions of caregivers regarding the use of ABC for children with ID/DD in South Africa. It also sought to incorporate the experiences of families of children with ID/DD who received, and intervenors who delivered, ABC in its first implementation in South Africa. Semi-structured interviews were conducted with 18 participants. Thematic analysis explicated 12 main themes: Intervention Strengths, Points of Concern, and Recommendations (Experts); Focus on Caregiver-child Relationship, and Intervention Targets and Duration (Caregivers); Benefits of ABC, and Cultural Considerations (ABC Recipients); Focused and Targeted, Value of Feedback, Supportive Supervision, Working Alliance, and Challenges Experienced (ABC Intervenors). Practice and training recommendations include psychoeducation for parents and training for intervenors that is ID/DD-specific, expanding supervision capacity, building intervenors' cultural/linguistic sensitivity and competence, accessing referral networks, including local Community Health Workers as intervenors, and greater flexibility in how the sessions are organized.

La intervención de Afectividad y Alcance del Bio-comportamiento (ABC) está dirigida a mejorar el funcionamiento socioemocional y regulatorio de los infantes bajo riesgo. Sin embargo, para usar el ABC para infantes y niños pequeñitos con discapacidades intelectuales / retrasos en el desarrollo (ID/DD) y dentro de nuevos contextos culturales, tal como en Sudáfrica, se requieren adaptaciones. Este estudio se propuso, por tanto, explorar las opiniones de expertos clínicos y las percepciones de quienes prestan el cuidado acerca del uso del ABC con niños con ID/DD en Sudáfrica. También buscaba incorporar las experiencias de familias de niños con ID/DD que recibían, así como de practicantes de la intervención que ofrecían el servicio de ABC durante su primera implementación en Sudáfrica. Se llevaron a cabo entrevistas semiestructuradas con 18 participantes. Análisis temáticos explicaron los 12 principales temas: Puntos Fuertes de la Intervención, Puntos que Preocupan y Recomendaciones (Expertos); Enfoque en la Relación Cuidador-Niño y Metas de Enfoque y Duración de la Intervención (Cuidadores); Beneficios del ABC y Consideraciones Culturales (Quienes recibían el ABC); Lo Enfocado y Diseñado como Meta, Valor de Ideas Recibidas, Supervisión con Apoyo, Alianza de Trabajo y Retos Experimentados (Practicantes de la Intervención ABC). Las recomendaciones de práctica y entrenamiento incluyen la psico-educación de padres, entrenamiento a quienes practican la intervención específicamente orientada a ID/DD, expandir la capacidad de supervisión, formar la sensibilidad y competencia cultural/lingüística de quienes practican la intervención, acceso a los sistemas de referencias, incluir Trabajadores de Salud Comunitarios como practicantes de la intervención y mayor flexibilidad en cómo organizar las sesiones.

L'attachement et le rattrapage bio-comportemental (en anglais Attachment and Biobehavioral Catch-up, soit ABC) est une intervention ciblée sur l'amélioration du fonctionnement socio-émotionnel et régulatoire de bébés à risques. Cependant, pour utiliser l'ABC pour des bébés/jeunes enfants avec des retards intellectuels et des retards du comportement (ID/DD) et dans des contextes culturels nouveaux, comme l'Afrique du Sud, des adaptations pourraient être nécessaires. Par conséquent cette étude s'est donné pour but d'explorer les opinions d'experts cliniques et les perceptions des personnes prenant soin d'un bébé quant à l'utilisation de l'ABC pour des enfants avec ID/DD en Afrique du Sud. On a aussi cherché à incorporer les expériences de familles d'enfants avec ID/DD qui ont reçu l'ABC, ainsi que des intervenants qui l'ont facilité, dans sa première mise en oeuvre en Afrique du Sud. Des entretiens semi-structurés ont été faits avec 18 participants. Une analyse thématique a explicité 12 thèmes principaux: Forces de l'Intervention, Points d'Inquiétude, et Recommandations (Experts); Accent sur la Relation Personne prenant soin de l'enfant-enfant et Cibles d'Intervention et Durée d'Intervention (Personnes prenant soin d'un bébé); Bénéfices de l'ABS, et Considérations Culturels (personnes ayant reçu l'ABC); Ciblé et Centré, Valeur du Retour, Supervision de Soutien, Alliance entre entités, et Défis Vécus (Intervenants ABC). Les recommandations de pratique et de formation incluent une psychoéducation pour les parents, une formation pour les intervenants qui est spécifique à l'ID/DD, l'élargissement de la capacité de supervision, le développement de la sensibilité et de la compétence culturelle/linguistique des intervenants, l'accès aux réseau d'orientation, y compris des Travailleurs de Santé Communautaires en tant qu'intervenants, et une plus grande flexibilité dans la manière dont les sessions sont organisées.

Maternal mental health and infant neurodevelopment at 6 months in a low-income South African cohort.

Maternal mental health disorders and the adverse consequences for infant neurodevelopment have received substantial research attention in high-income countries over the past five decades. In Africa, where relatively little work has been done on this topic, researchers have largely focused on infant physical health outcomes. This longitudinal study investigated the neurodevelopment of infants at 6 months post-term with exposure to mothers with a clinical diagnosis of persistent mental health disorders residing in low-income communities in Cape Town, South Africa. Adjusted models revealed no significant differences on the Bayley Scales of Infant and Toddler Development (BSID-III) domains (cognitive, motor, language, socio-emotional, and adaptive behavior) between infants exposed to maternal mental health disorders (n = 62) and the comparison group (n = 35) at 3 and 6 months. Subgroup analyses found no significant differences on the BSID-III domains between infants with exposure to mood disorders (n = 31), as well as infants with exposure to comorbid (i.e., a combination of two or three) mental health disorders (n = 14) and the comparison group. However, infants with exposure to psychotic disorders (n = 14) scored significantly lower on the cognitive and the motor domains and the fine motor subscale. These novel data provide an important contribution to the scientific literature especially in the field of maternal psychotic disorders in Africa.

Los trastornos de la salud mental materna y las consecuencias adversas para el neurodesarrollo del infante han recibido una considerable atención investigativa en países de altos niveles económicos a lo largo de las últimas cinco décadas. En África, donde se ha llevado a cabo relativamente poco trabajo sobre este tema, los investigadores se han enfocado por la mayor parte en los resultados de la salud física del infante. Este estudio longitudinal investigó el neurodesarrollo de infantes a los 6 meses después del término de gestación que habían sido expuestos a madres con un diagnóstico clínico de trastornos de salud mental persistentes quienes residían en comunidades de bajos recursos en Ciudad del Cabo, Sudáfrica. Los ajustados modelos no revelaron significativas diferencias en los dominios de las Escalas Bayley del Desarrollo del Infante y Niños Pequeñitos (BSID-III) (cognitivo, motor, lenguaje, comportamiento socioemocional y de adaptación) entre los infantes que habían estado expuestos a los trastornos de salud mental materna (n = 62) y el grupo de comparación (n = 35) a los 3 y 6 meses. Los análisis de subgrupo no encontraron diferencias significativas en los dominios de BSID-III entre los infantes que habían estado expuestos a los trastornos de estado de ánimo (n = 31), así como los infantes que habían estado expuestos a trastornos de salud mental comórbidos (v.g. una combinación de dos o tres) (n = 14) y el grupo de comparación. Sin embargo, los infantes que habían estado expuestos a trastornos sicóticos (n = 14) tuvieron puntajes significativamente más bajos en los dominios cognitivo y motor, así como en la subescala de las habilidades motoras finas. Estos novedosos datos ofrecen una contribución importante a la literatura científica especialmente en el campo de los trastornos sicóticos maternos en África.

Les troubles de la santé mentale maternelle et les conséquences négatives pour le neurodéveloppement du nourrisson ont reçu l'attention de beaucoup de recherches dans les pays à revenu élevé ces cinquante dernières années. En Afrique où relativement peu de travail a été fait sur ce sujet, les chercheurs se sont en grande partie penchés sur les résultats de la santé physique des nourrissons. Cette étude longitudinale s'est penchée sur le neurodéveloppement de nourrissons à 6 mois après terme avec une exposition aux mères avec un diagnostic clinique de troubles de la santé mentale persistants, résidant dans des communautés défavorisées à Cape Town, en Afrique du Sud. Les modèles ajustés n'ont révélé aucunes différences importantes dans les domaines (cognitif, moteur, langage, comportement socio-émotionnel et comportement adaptif) des Echelles Bayley du Développement du Nourrisson et du Jeune Enfant (BSID-III) entre les nourrissons exposés à des troubles de la santé mentale maternelle (n = 62) et le groupe de comparaison (n-35) à 3 et 6 mois. Les analyses de sous-groupes n'ont trouvé aucunes différences concernant les domaines BSID-III entre les nourrissons avec une exposition à des troubles de l'humeur (n-31), ainsi que des nourrissons avec une exposition à des troubles de santé mentale comorbides (c'est-à-dire une combinaison de deux ou trois) (n-14) et le groupe de comparaison. Cependant, les nourrissons ayant été exposés à des troubles psychotiques (n = 14) ont reçu des scores bien plus bas dans le domaine cognitif, dans le domaine moteur, et à la sous-échelle motrice fine. Ces nouvelles données offrent une contribution importante aux recherches scientifiques, surtout dans le domaine des troubles psychotiques maternels en Afrique.

"I think it's communication and trust and sharing everything": Qualitative evidence for a model of healthy intimate relationships in Black women living with HIV and men in KwaZulu-Natal, South Africa.

In South Africa, couple-based interventions (CBIs) have been used to increase HIV testing, reduce HIV transmission, and shift relationship dynamics. To understand local definitions of healthy relationships, this study sought to collect qualitative data on a model of healthy relationships in a semi-rural area of KwaZulu-Natal, South Africa. We conducted semi-structured qualitative interviews with HIV-positive women (n = 15) and men of mixed HIV status (n = 15) who were in heterosexual, monogamous relationships (not with each other). Thematic analyses guided coding. Three primary healthy relationship behaviour themes emerged, labelled open communication, couple-level problem-solving, and active relationship building, which were related to various relationship facets (trust, support, respect, commitment, and connection). We purposively explored contextual themes, namely the role of HIV, positive community involvement, and power dynamics, to better situate the healthy relationship behaviour themes. HIV was not central to relationship conceptualisations and three different power structures (shared power/flexible gender norms, shared power/traditional gender norms, male-dominated power/traditional gender norms) were described as being healthy. This model of healthy relationships is similar to observed definitions in other African countries and in high-income settings. Findings can inform HIV programming content for couples in KwaZulu-Natal, particularly the active relationship building component.

En Sudáfrica, se han utilizado intervenciones basadas en la pareja para aumentar las pruebas de detección de VIH, disminuir la transmisión del VIH y cambiar la dinámica de las relaciones. Para comprender las definiciones locales de relaciones saludables, en el presente estudio se procuró recoger datos cualitativos sobre un modelo de relaciones saludables en un área semirrural de KwaZulu-Natal, Sudáfrica. Realizamos entrevistas cualitativas semiestructuradas con mujeres VIH positivo (n= 15) y hombres de estados variados en relación con el VIH (n = 15) que estaban en relaciones heterosexuales y monógamas (no entre ellos). Los análisis temáticos guiaron la codificación. Surgieron tres temas principales de conducta en las relaciones saludables: comunicación abierta marcada, resolución de problemas a nivel de la pareja, y construcción activa de la relación, que estuvieron relacionados con varios aspectos de las relaciones (la confianza, el apoyo, el respeto, el compromiso y la conexión). Analizamos específicamente temas contextuales, por ejemplo, el papel del VIH, la participación positiva en la comunidad y la dinámica de poder para ubicar mejor los temas de conducta en las relaciones saludables. El VIH no fue fundamental para las conceptualizaciones de las relaciones y se describieron como saludables tres estructuras de poder diferentes (poder compartido/normas flexibles de género, poder compartido/normas tradicionales de género, poder predominantemente masculino/normas tradicionales de género). Este modelo de relaciones saludables es similar a las definiciones observadas en otros países africanos y en ámbitos de ingresos altos. Los resultados pueden orientar el contenido de los programas sobre el VIH para parejas en KwaZulu-Natal, particularmente el componente de construcción activa de la relación.

Experiencia de la Brigada Médica Cubana "Henry Reeve" en el enfrentamiento a la COVID-19 en Sudáfrica

RESUMEN Introducción: Sudáfrica, nación más afectada por el SARS-CoV-2 en África, solicitó ayuda médica a Cuba. El Contingente Internacional de Médicos Especializados en Situaciones de Desastres y Graves Epidemias "Henry Reeve" envió una brigada para reforzar la colaboración médica. Objetivo: Describir la composición del grupo, actividades asistenciales realizadas, experiencia e impacto del trabajo de la Brigada Médica Cubana "Henry Reeve" en Sudáfrica para el enfrentamiento a la COVID-19 y otros problemas de salud. Método: Se realizó una investigación descriptiva transversal, entre abril 2020 y mayo 2021. Se confeccionaron instrumentos para la recolección de la información diaria y semanal, así como el modelo 241-492 del Minsap con periodicidad mensual. Resultados: La brigada estuvo conformada por 184 colaboradores: 114 médicos (62,0 %) y 70 licenciados y técnicos de salud (38,0 %). Predominó el sexo masculino (61,4 %) y la edad promedio fue de 43 años. Fueron atendidos más de 255 940 pacientes, de ellos, 116 234 relacionados con la COVID-19. Se realizaron 1 294 intervenciones quirúrgicas, 320 partos y 44 692 procederes de enfermería; lo que contribuyó a salvarle la vida a 1 519 pacientes, entre ellos el 66 % fue positivo a COVID-19. Se lamentó el fallecimiento de 643 pacientes, el 97 % por complicaciones de dicha enfermedad. Se destacó el trabajo realizado por epidemiólogos, electromédicos, bioestadísticos y farmacéuticos. Conclusiones: Se reconoce la meritoria labor desempeñada por la Brigada Médica Cubana "Henry Reeve" en el enfrentamiento a la COVID-19 y su contribución en instituciones del Sistema Nacional de Salud de Sudáfrica.

ABSTRACT Introduction: South Africa, the nation most affected by SARS-CoV-2 in Africa, requested medical assistance from Cuba. The Henry Reeve International Contingent of Specialized Doctors in Disaster Situations and Serious Epidemics sent a brigade to strengthen medical collaboration. Objective: Review the composition of the group, the assistance activities carried out, experience and impact of the work supported by the "Henry Reeve" Cuban Medical Brigade in South Africa to confront COVID-19 and other health problems. Method: A descriptive cross-sectional study was carried out between April 2020 and May 2021. Some instruments were built to collect daily and weekly information, as well as the Minsap model 241-492 with monthly periodicity. Results: The brigade was made up of 184 collaborators: 114 physicians (62.0%) and 70 health technicians and graduates (38.0%). Sex male was predominant (61.4%) and the average age was 43 years. More than 255,940 patients were attended at the field hospital, of which 116,234 were COVID-19 confirmed patients. A total of 1,294 surgical interventions, 320 deliveries and 44,692 nursing procedures were performed, which contributed to saving the lives of 1,519 patients, 66% of whom were COVID-19 positive. The death of 643 patients was regretted, 97% of them due to disease complications. The work carried out by epidemiologists, medical equipment maintenance specialists, biostatisticians and pharmacists was highlighted. Conclusions: The meritorious work carried out by the "Henry Reeve" Cuban Medical Brigade in the fight against the COVID-19 pandemic and its support to health institutions of the South African National Health System is acknowledged.

RESUMO Introdução: A África do Sul, a nação mais afetada pelo SARS-CoV-2 na África, solicitou ajuda médica de Cuba. O Contingente Internacional de Médicos Especializados em Situações de Desastre e Epidemias Graves "Henry Reeve" enviou uma brigada para reforçar a colaboração médica. Objetivo: Descrever a composição do grupo, as atividades assistenciais realizadas, a experiência e o impacto do trabalho da Brigada Médica Cubana "Henry Reeve" na África do Sul para enfrentar o COVID-19 e outros agravos à saúde. Método: Pesquisa descritiva transversal realizada entre abril de 2020 e maio de 2021. Foram confeccionados instrumentos de coleta de informações diárias e semanais, bem como o modelo Minsap 241-492 com periodicidade mensal. Resultados: A brigada era composta por 184 colaboradores: 114 médicos (62,0%) e 70 graduados e técnicos em saúde (38,0%). Predominou o sexo masculino (61,4%) e a média de idade foi de 43 anos. Mais de 255.940 pacientes foram tratados, deles 116.234 relacionados ao COVID-19. Foram realizadas 1.294 intervenções cirúrgicas, 320 partos e 44.692 procedimentos de enfermagem; o que contribuiu para salvar a vida de 1.519 pacientes, entre eles 66% eram positivos para COVID-19. A morte de 643 pacientes foi lamentada, 97% devido a complicações desta doença. O trabalho realizado por epidemiologistas, eletromédicos, bioestatísticos e farmacêuticos foi destaque. Conclusões: É reconhecido o meritório trabalho realizado pela Brigada Médica Cubana "Henry Reeve" no enfrentamento ao COVID-19 e sua contribuição às instituições do Sistema Nacional de Saúde da África do Sul.

Practical actions for applied systematic conservation planning.

Systematic conservation planning is intended to inform spatially explicit decision making. Doing so requires that it be integrated into complex regulatory and governance processes, and there are limited instances where this has been achieved effectively. South Africa is a global leader in the application of conservation plans, the outputs of which are widely used for spatial planning and decision making in many spheres of government. We aimed to determine how conservation planning in the country progressed from theory to implementation, and to identify practical actions that enabled this transition, by assessing temporal trends in the characteristics of conservation plans (1990-2017, n = 94). Since 2010 conservation planning has entered an operational period characterized by government leadership of plans, administrative rather than ecological planning domains, decreasing size of planning units, increasing emphasis on end-user products, and scheduled revision of plans. Key actions that enabled this progression include transitioning leadership of plans from scientists to practitioners, building capacity within implementing agencies, creating opportunities to integrate plans in legislative processes, establishing a strong community of practice, adopting implementation-focused methods, and balancing standardization with innovation. Learning from this model will allow other countries, particularly those with a similar megadiverse, developing context, to operationalize conservation planning into spatial planning and decision making.

Acciones Prácticas para la Aplicación de la Planeación Sistemática de la Conservación Resumen La intención de la planeación sistemática de la conservación es informar la toma de decisiones espacialmente explícitas. Para lograr esto se requiere la integración de la planeación sistemática dentro de los complejos procesos regulatorios y de gobernanza. Actualmente existen instancias limitadas en las que lo anterior se ha conseguido de manera efectiva. Sudáfrica es un líder mundial en la aplicación de planes de conservación, cuyos resultados se utilizan ampliamente para la planeación espacial y la toma de decisiones en muchas esferas del gobierno. Buscamos determinar cómo la planeación de la conservación ha progresado en este país desde la teoría hasta la implementación e identificar las acciones prácticas que permitieron esta transición, esto mediante la evaluación de tendencias temporales en las características de los planes de conservación (1990-2017, n = 94). Desde 2010 la planeación de la conservación ha entrado en un periodo operativo caracterizado por el liderazgo gubernamental de los planes, dominios administrativos en lugar de dominios ecológicos, la reducción del tamaño de las unidades de planeación, el incremento del énfasis sobre los productos de usuario final y una revisión programada de los planes. Las acciones clave que permitieron esta progresión incluyen la transición del liderazgo de los planes de los científicos hacia los practicantes, el desarrollo de capacidades dentro de las agencias implementadoras, la creación de oportunidades para integrar los planes dentro de los procesos legislativos, el establecimiento de una comunidad de práctica fuerte, la adopción de métodos enfocados en la implementación y el balance entre la estandarización y la innovación. El aprendizaje que proporciona este modelo permitirá que otros países, particularmente aquellos con un contexto similar en cuanto al desarrollo y a la megadviversidad, conduzcan la planeación de la conservación hacia la planeación y la toma de decisiones espacialmente explícitas.

The mental foramen in dry human mandibles of adult South Africans: an anatomical study / El foramen mental en mandíbulas humanas secas de adultos sudafricanos: un estudio anatómico

The objective of the study was to investigate the position, position symmetry, shape and number of the mental foramen in a heterogeneous South African population. Knowledge of the precise position of MF in maxillofacial surgery is critical for an accurate local anaesthesia; and can provide a landmark in forensic or medico legal cases. Dry adult human mandibles (n = 325) were selected and classified by ancestry. The sample comprised male-to-female ratio of 1.2:1. Observations were made for the position, position symmetry, shape and number of the mental foramen. There was a substantial to perfect agreement (p < 0.001) for most observations, except for the shape of the MF on the right side of the mandible that had a fair agreement (K = 0.25; P > 0.05). PIV of the MF is shown as the most prevalent position. PIII and IV were commonly observed in males and females respectively. PII was commonly observed in the males of European descent, while PIII was observed in male African and Mixed descents and female European descents. There was no significant difference in the symmetric analysis of MF amongst male and female (p = 0.059) and between ancestry (p = 0.455). But also, an oval shape of MF was the most common across subpopulations and ancestries, with 2 (2 %) and 3 (0.46 %) of the AMFs present. This study is the first comprehensive description of the MF in the South African population, and could be very useful in forensic anthropology in the South Africa population.

El objetivo de este estudio fue investigar, en una población sudafricana heterogénea, la posición, simetría de posición, forma y número de forámenes mentales (FM). El conocimiento de la localización exacta del FM en la cirugía maxilofacial es crítico para una anestesia local precisa y puede proporcionar un punto de referencia en casos legales forenses o médicos. Se seleccionaron 325 mandíbulas humanas secas adultas y clasificadas por ascendencia. La muestra relación hombre-mujer fue de 1,2:1. Las observaciones fueron realizadas para la posición, simetría de la posición, forma y el número forámenes mentales. Se alcanzó la perfección de concordancia (p < 0,001) para la mayoría de las observaciones, a excepción de la forma intermedia en el lado derecho de la mandíbula el cual presentó un acuerdo justo (K = 0,25; p > 0,05). La PIV de la MF se muestra como la posición más prevalente. PIII y IV fueron observados comúnmente en hombres y mujeres, respectivamente. La PII se observó comúnmente en los varones de ascendencia europea, mientras que el PIII se observó en descendientes africanos y mixtos masculinos y descendientes femeninos europeos. No hubo diferencias significativas en el análisis simétrico del FM entre hombres y mujeres (p = 0,059) y entre ascendencia (p = 0,455). Una forma ovalada de FM fue la más común a través de subpoblaciones y ancestros, con 2 (2 %) y 3 (46 %) del con la presencia de un foramen mental accesorio. Este estudio es la primera descripción comprensiva del FM en la población sudafricana, y podría ser muy útil en antropología forense en la población de Sudáfrica.

Post-mortem brain weight reference range for a select South African population / Rango de referencia del peso cerebral post-mortem para una población sudafricana seleccionada

Human brain weight plays a significant role in clinical and forensic settings, as cause of death may affect brain weight; and may be used in the detection of abnormalities associated with neurological disorders. Brain weights are geography specific and incorrect reference ranges may hinder interpretation during clinical and autopsy settings. This study assessed the influence of age, sex and race on post-mortem brain weights of a select medico-legal population; to create a geographically relevant reference range of brain weights for the eThekwini region. Standard autopsy protocol and procedures, using the Ghon method of dissection were implemented on four hundred and eighty-one decedents. Decedents were obtained from a medico-legal state mortuary in the eThekwini region, KwaZulu-Natal, South Africa from June 2015 to March 2016. Black South African decedents comprised 83.6 % (402/481) of the sample population and whom reference ranges were formulated. Male decedents attained peak weight significantly earlier in the 11-20 year age interval, whereas female decedents in the 41-50 year age interval. However, no significance was observed between brain weight and age (p=0.799). Significant differences between sexes was noted, with mean male brains weighing significantly more (137.69 g, p<0.001). The mean brain weights were 1404.82±145.07 g and 1267.13±163.96 g in Black males and females, respectively. Post-mortem brain weights were predominantly of Black South Africans, with brain weights of both sexes comparably like those reported in the Northern hemisphere. However, brain weights attained peak weight at different age intervals, with variant brain weights between different racial groups within South Africa. Therefore, brain weight reference ranges may not be applicable to another geographic locality.

El peso del cerebro humano tiene un rol importante en los entornos clínicos y forenses, ya que la causa de la muerte puede afectar el peso del éste; además puede se puede usar en la detección de anomalías asociadas con trastornos neurológicos. Los pesos cerebrales son específicos de la geografía y rangos de referencia incorrectos pueden dificultar la interpretación en la clínica y la autopsia. Este estudio evaluó la influencia de la edad, el sexo y la raza en el peso cerebral post-mortem de una población médico-legal seleccionada; para crear un rango de referencia geográficamente relevante de pesos cerebrales para la región eThekwini. El protocolo y los procedimientos estándar de autopsia, utilizando el método de disección de Ghon, se implementaron en 481 cadáveres. Los cadáveres se obtuvieron de un depósito de cadáveres médico-legal en la región de eThekwini, KwaZulu-Natal, Sudáfrica, entre junio de 2015 a marzo de 2016. Los cadáveres, afro descendientes de Sudáfrica, comprendían el 83,6 % (402/ 481) de la población de la muestra y se formularon los rangos de referencia. Los fallecidos masculinos alcanzaron el peso máximo significativamente más temprano en el intervalo de edad de 11-20 años, mientras que las mujeres fallecidas, correspondió al intervalo de edad de 41 años. Sin embargo, no se observó significación entre el peso del cerebro y la edad (p = 0,799). Se observaron diferencias significativas entre sexos, con cerebros masculinos medios que pesaban significativamente más (137,69 g, p<0,001). Los pesos cerebrales medios fueron 1404,82±145,07 g y 1267,13±163,96 g en hombres y mujeres negros, respectivamente. Los pesos cerebrales post-mortem fueron predominantemente de sudafricanos negros, con pesos cerebrales de ambos sexos comparables a los reportados en el hemisferio norte. Sin embargo, los pesos cerebrales alcanzaron el peso máximo a diferentes intervalos de edad, con pesos cerebrales variables entre diferentes grupos raciales dentro de Sudáfrica. Por lo tanto, los rangos de referencia de peso del cerebro pueden no ser aplicables a otra localidad geográfica.

Ciência, justiça e antropologia no debate sul-africano da AIDS: produção de sensibilidades e regulação moral entre especialistas / Science, justice and anthropology in the south african debate on AIDS: making sensibilities and moral regulation among specialists / Ciencia, justicia y antropología en el debate surafricano del SIDA: producción de sensibilidades y regulación moral entre especialistas

Resumo O texto relata minha experiência enquanto pesquisava o :debate da AIDSd ocorrido na África do Sul na década de 2000. A partir de pesquisa em arquivos, entrevistas e observação participante em ambientes acadêmicos e entre especialistas da AIDS, exploro as críticas de alguns dos meus interlocutores contra o suposto relativismo e a alegada postura dos antropólogos em face da controvérsia. Em meio a constantes apelos para combater o negacionismoc da AIDS, desconfiança e mesmo aberto rechaço ao pensamento antropológico, analiso minha inserção em redes de pesquisadores e ativistas na Cidade do Cabo, à luz do enfrentamento entre "ortodoxos" ou defensores da ciência da AIDSc e negacionistasn ou dissidentesd. A dificuldade habitual da pesquisa etnográfica é atualizada neste caso, mas ele também coloca um novo desafio: como pode o conhecimento antropológico contribuir para uma melhor compreensão de disputas, sobretudo quando, do ponto de vista .nativon, tais disputas parecem insuperáveis ou inexistem?

Abstract This paper describes my doctoral fieldwork while researching the "AIDS debate" in South Africa. From archives, interviews, and participant observation in academic contexts and expert communities, I explore criticisms raised by some interlocutors against the alleged anthropological relativism and what they regard as the unsuitable position of anthropologists into the controversy. Amid pressure to 'combat AIDS denialism', mistrust and even open rejection of the anthropological thought, I also consider my personal situation into the academic and activists networks in Cape Town in light of the clash between "orthodox" or supporters of "science of AIDS" and "denialists" or "dissidents". The usual difficulty of the ethnographic research is updated in this case, but it also brings up a new challenge: how anthropological knowledge can contribute to a better understanding of disputes and promote agreements especially when from native's viewpoint such disputes seem nonexistent or insurmountable?

Resumen Este texto relata mi experiencia mientras investigaba el "debate del SIDA" ocurrido en Sudáfrica en la década de 2000. A partir del trabajo en archivos históricos, entrevistas y observación participante en ambientes académicos y entre especialistas del SIDA, exploro las críticas de algunos de mis interlocutores contra el supuesto relativismo y la alegada postura de los antropólogos durante la controversia. En medio de constantes llamados para :combatir el negacionismoc del SIDA, desconfianza e incluso un abierto rechazo del pensamiento antropológico, analizo mi participación en redes de investigadores e activistas en Ciudad del Cabo, a la luz del enfrentamiento entre ortodoxoso o defensores de la ciencia del SIDAc y negacionistasn o disidentesd. Este caso actualiza la dificultad habitual del trabajo etnográfico, pero también sugiere un nuevo reto: ¿cómo puede el conocimiento antropológico contribuir a una mejor comprensión de disputas, sobre todo cuando, desde el punto de .nativon, tales disputas parecen insuperables o inexistentes?

Factors associated with the health and cognition of 6-year-old to 8-year-old children in KwaZulu-Natal, South Africa.

OBJECTIVE: To investigate 6-year-old to 8-year-old children's health, nutritional status and cognitive development in a predominantly rural area of KwaZulu-Natal, South Africa. METHODS: Cohort study of 1383 children investigating the association of demographic variables (area of residence, sex, pre-school education, HIV status, height for age and haemoglobin level) and family variables (socioeconomic status, maternal and paternal level of education), with children's cognitive performance. The latter was measured using the Grover-Counter Scale of Cognitive Development and subtests of the Kaufman Assessment Battery for Children, second edition (KABC-II). General linear models were used to determine the effect of these predictors. RESULTS: Area of residence and height-for-age were the statistically significant factors affecting cognitive test scores, regardless of attending pre-school. Paternal level of education was also significantly associated with the cognitive test scores of the children for all three cognitive test results, whereas HIV status, sex and their socioeconomic status were not. CONCLUSION: Children with low cognitive scores tended to be stunted (low height-for-age scores), lacked pre-school education and were younger. Area of residence and their parents' educational level also influenced their cognition.

Morphometric study of lumbar vertebrae in adult South African subjects / Estudio morfométrico de las vértebras lumbares en sujetos adultos de Sudáfrica

Lumbar vertebral dimensions provide vital clinical information of immense diagnostic benefits to medical experts. The present study provides data for lumbar vertebral dimensions of a cohort of specimens of South African females and males. Measurements were obtained from lumbar vertebrae from the osteological collections in the Discipline of Clinical Anatomy, Nelson Mandela School of Medicine using a digital caliper. The antero-posterior body diameter (APD), interpedicular distance (IPD), midsagittal diameter (MSD) and pedicle length (PL) were measured while ratio of MSD to APD was calculated. Results showed gradual increase from L1 to L5 for mean APD and IPD, and a decrease for mean PL from L1 to L5. Mean MSD was observed to present a "U" curve pattern from L1 to L5, while MSD/APD ratio decreased from L2 downwards. We report that certain lumbar dimensions also showed significant correlation with age at distinct lumbar levels. The present data provides a baseline of lumbar vertebral morphology for the South African adult cohort and requires further investigations with larger cohort.

Las dimensiones lumbares vertebrales proporcionan información vital en la clínica para alcanzar un diagnóstico correcto. El presente estudio proporciona datos de las dimensiones vertebrales lumbares en una cohorte de hombres y mujeres de Sudáfrica. Las mediciones de las vértebras lumbares se obtuvieron de colecciones osteológicas correspondientes a la Cátedra de Anatomía Clínica, de la Escuela de Medicina Nelson Mandela. Se utilizó un calibrador digital. Se midieron el diámetro antero-posterior del cuerpo vertebral (DPA), la distancia interpedicular (DIP), el diámetro sagital mediano (DSM) y la longitud del pedículo (LP); y se calculó la relación de DSM con DPA. Los resultados mostraron un aumento gradual de L1 a L5 para la mediana de DPA y DIP, y una disminución de la media de LP de L1 a L5. La media de DSM presentó un patrón de curva en "U" de L1 a L5, mientras que el índice DSM / DPA disminuyó de L2 hacia inferior. Ciertas dimensiones lumbares también mostraron una correlación significativa con la edad en los distintos niveles lumbares. El presente estudio proporciona datos acerca de la morfología vertebral lumbar para una cohorte de adultos de Sudáfrica, y consideramos que se requieren de más investigaciones con una cohorte más amplia.

REFLECTIVE PRACTICE IN INFANT MENTAL HEALTH-A SOUTH AFRICAN PERSPECTIVE.

Reflective practice forms a pivotal part of mental health intervention in a setting where language and cultural differences require working together with a community counselor for language interpretation. Reflective practice in infant mental health began with Esther Bick's () infant observations and continued with Selma Fraiberg's () parent-infant psychotherapy. These two models formed the basis of the practice of infant mental health in a community in South Africa. A clinical example will highlight the importance of culturally informed observation that is then reflected upon. A qualitative study that examined the interaction among the participants in three clinical settings shows that a sustained partnership and tolerance for flexibility lie at the heart of good practice in intercultural settings. Object-relations theory offers an additional, in-depth understanding of the underlying psychic processes in reflective practice.

Impact of the introduction of mandatory generic substitution in South Africa: private sector sales of generic and originator medicines for chronic diseases.

OBJECTIVE: To assess the impact of mandatory offer of generic substitution, introduced in South Africa in May 2003, on private sector sales of generic and originator medicines for chronic diseases. METHODS: Private sector sales data (June 2001 to May 2005) were obtained from IMS Health for proton pump inhibitors (PPIs; ATC code A02BC), HMG-CoA reductase inhibitors (statins; C10AA), dihydropyridine calcium antagonists (C08CA), angiotensin-converting enzyme inhibitors (ACE-I; C09AA) and selective serotonin reuptake inhibitors (SSRIs; N06AB). Monthly sales were expressed as defined daily doses per 1000 insured population per month (DDD/TIM). Interrupted time-series models were used to estimate the changes in slope and level of medicines use after the policy change. ARIMA models were used to correct for autocorrelation and stationarity. RESULTS: Only the SSRIs saw a significant rise in level of generic utilisation (0.2 DDD/TIM; P < 0.001) and a fall in originator usage (-0.1 DDD/TIM; P < 0.001) after the policy change. Utilisation of generic PPIs fell (level 0.06 DDD/TIM, P = 0.048; slope 0.01 DDD/TIM, P = 0.043), but utilisation of originator products also grew (level 0.05 DDD/TIM, P < 0.001; slope 0.003, P = 0.001). Generic calcium antagonists and ACE-I showed an increase in slope (0.01 DDD/TIM, P = 0.016; 0.02 DDD/TIM, P < 0.001), while the originators showed a decrease in slope (-0.003 DDD/TIM, P = 0.046; -0.01 DDD/TIM, P < 0.001). There were insufficient data on generic statin use before the policy change to allow for analysis. CONCLUSION: The mandatory offer of generic substitution appeared to have had a quantifiable effect on utilisation patterns in the 2 years after May 2003. Managed care interventions that were already in place before the intervention may have blunted the extent of the changes seen in this period. Generic policies are an important enabling provision for cost-containment efforts. However, decisions taken outside of official policy may anticipate or differ from that policy, with important consequences.

Diarrhoea in children under five years of age in South Africa (1997-2014).

OBJECTIVE: To present evidence from available reliable published data on the prevalence, incidence and severity of diarrhoea in children aged under five years in South Africa. METHODS: We searched seven electronic databases. Two reviewers assessed the studies independently and extracted outcome data. The heterogeneity of the studies did not allow for a meta-analysis. RESULTS: We found only one nationally representative study conducted in 1998 reporting a diarrhoea prevalence of 13% in children under five. Other studies were conducted in smaller settings across the country. Diarrhoea incidence was 10.13 per 1000 person years in children admitted to a tertiary hospital. Three studies reported severity of diarrhoea; however, they differed across study settings and time period. CONCLUSION: The paucity of nationally representative prevalence data for SA necessitates more national surveys with standardised data-collection methods to allow for more effective comparisons.

Evaluation of syndromic management guidelines for treatment of sexually transmitted infections in South African women.

OBJECTIVE: To evaluate the performance of three different guidelines for the management of vaginal discharge syndrome (VDS) for women living in a rural setting in South Africa. METHODS: We conducted a secondary analysis of data from a cross-sectional study in Mopani District, South Africa. The 2015 and 2008 guidelines of the South African Department of Health (DoH) and the most recent WHO guidelines were evaluated for adequate treatment of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Trichomonas vaginalis infection. RESULTS: Of the 489 women included in this analysis, 35% presented with VDS according to the DoH and 30% per WHO definition of VDS. Fifty-six per cent of the women with VDS would be treated adequately for these STI when using the 2015 DoH guideline, whereas 76% (P = 0.01) and 64% (P = 0.35) would receive adequate treatment with the 2008 DoH and WHO guidelines, respectively. Of the symptomatic women who tested negative for all four STI, STI treatment would have been indicated for 36% as per 2015 DoH guideline vs. 69% (P < 0.001) per 2008 DoH and 67% (P < 0.001) per WHO guidelines. CONCLUSION: A considerable proportion of symptomatic women infected with these common curable STI would receive adequate treatment when using a syndromic management approach, and significant differences exist between the three guidelines. Many symptomatic women without these STI receive broad-spectrum antibiotics, so new approaches are needed to improve syndromic STI control.

Supervised oral HIV self-testing is accurate in rural KwaZulu-Natal, South Africa.

OBJECTIVES: To achieve UNAIDS 90-90-90 targets, alternatives to conventional HIV testing models are necessary in South Africa to increase population awareness of their HIV status. One of the alternatives is oral mucosal transudates-based HIV self-testing (OralST). This study describes implementation of counsellor-introduced supervised OralST in a high HIV prevalent rural area. METHODS: Cross-sectional study conducted in two government-run primary healthcare clinics and three Médecins Sans Frontières-run fixed-testing sites in uMlalazi municipality, KwaZulu-Natal. Lay counsellors sampled and recruited eligible participants, sought informed consent and demonstrated the use of the OraQuick(™) OralST. The participants used the OraQuick(™) in front of the counsellor and underwent a blood-based Determine(™) and a Unigold(™) rapid diagnostic test as gold standard for comparison. Primary outcomes were user error rates, inter-rater agreement, sensitivity, specificity and predictive values. RESULTS: A total of 2198 participants used the OraQuick(™) , of which 1005 were recruited at the primary healthcare clinics. Of the total, 1457 (66.3%) were women. Only two participants had to repeat their OraQuick(™) . Inter-rater agreement was 99.8% (Kappa 0.9925). Sensitivity for the OralST was 98.7% (95% CI 96.8-99.6), and specificity was 100% (95% CI 99.8-100). CONCLUSION: This study demonstrates high inter-rater agreement, and high accuracy of supervised OralST. OralST has the potential to increase uptake of HIV testing and could be offered at clinics and community testing sites in rural South Africa. Further research is necessary on the potential of unsupervised OralST to increase HIV status awareness and linkage to care.

Socio-economic differences in HIV/AIDS mortality in South Africa.

OBJECTIVES: To quantify socio-economic differences in the risk of HIV/AIDS mortality in South Africa for different measures of socio-economic status. METHODS: Systematic literature search in Web of Knowledge and PubMed. Measures of relative risk (RR) were pooled separately for education, income, assets score and employment status as measures of socio-economic status, using inverse-variance weighted DerSimonian-Laird random effects meta-analyses. RESULTS: Ten studies were eligible for inclusion comprising over 175 000 participants and 6700 deaths. For income (RR 1.55, 95% confidence interval (CI) 1.15-2.09), assets score (RR 1.63, 95% CI 1.12-2.36) and employment status (RR 1.52, 95% CI 1.21-1.92), persons of low socio-economic status had an over 50% higher risk of dying from HIV/AIDS. The RR of 1.10 for education was not significant (95% CI 0.74-1.65). CONCLUSIONS: Future research should identify effective strategies to reduce HIV/AIDS mortality and alleviate the consequences of HIV/AIDS deaths, particularly for poorer households.

Scale dependency in effectiveness, isolation, and social-ecological spillover of protected areas.

Protected areas are considered vital for the conservation of biodiversity. Given their central role in many conservation strategies, it is important to know whether they adequately protect biodiversity within their boundaries; whether they are becoming more isolated from other natural areas over time; and whether they play a role in facilitating or reducing land-cover change in their surroundings. We used matching methods and national and local analyses of land-cover change to evaluate the combined effectiveness (i.e., avoided natural-cover loss), isolation (i.e., changes in adjacent areas), and spillover effects (i.e., impacts on adjacent areas) of 19 national parks in South Africa from 2000 to 2009. All parks had either similar or lower rates of natural-cover loss than matched control samples. On a national level, mean net loss of natural cover and mean net gain of cultivation cover decreased with distance from park boundary, but there was considerable variation in trends around individual parks, providing evidence for both increased isolation and buffering of protected areas. Fourteen parks had significant positive spillover and reduced natural-cover loss in their surroundings, whereas five parks experienced elevated levels of natural-cover loss. Conclusions about social-ecological spillover effects from protected areas depended heavily on the measures of land-cover change used and the scale at which the results were aggregated. Our findings emphasize the need for high-resolution data when assessing spatially explicit phenomena such as land-cover change and challenge the usefulness of large-scale (coarse grain, broad extent) studies for understanding social-ecological dynamics around protected areas.

Vergence anomalies in a sample of high school students in South Africa.

AIM: To study the prevalence of nearpoint vergence anomalies (convergence insufficiency, convergence excess and fusional vergence dysfunction) and association with gender, age groups, grade level and study site (suburban and rural). METHODS: The study design was cross sectional and data was analyzed for 1201 high school students aged 13-19 years who were randomly selected from 13 high schools in uMhlathuze municipality. Of the total sample, 476 (39.5%) were males and 725 (60.5%) were females. The visual functions evaluated included refractive errors, heterophoria, near point of convergence, accommodative functions and fusional vergences. Possible associations between vergence anomalies and demographic variables (gender, age groups, school grade levels and study site) were explored. RESULTS: Prevalence estimates were 11.8%, 6% and 4.3% for low suspect, high suspect and definite convergence insufficiency, and 1.9% for the pseudo convergence insufficiency. Convergence excess prevalence was 5.6%, and fusional vergence dysfunction was 3.3%. The prevalence of low suspect CI was significantly higher in suburban than in rural participants (p=0.01), the reverse was the case for pseudoconvergence insufficiency while the prevalence of convergence excess was significantly higher in the younger than in the older age group (p=0.02). No other category showed any statistically significant associations with vergence anomalies. CONCLUSION: The prevalence estimates for vergence anomalies in a sample of black high school students in South Africa were relatively low. Only study location and age influenced some vergence anomalies. Identification and referrals are important steps toward diagnosis and treatment for vergence anomalies. Further studies to compare vergence anomalies in various racial populations will be relevant.