ABSTRACT
OBJECTIVE: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status. METHOD: This cross-sectional study included 41 participants consisting of 31 malnourished, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. IGFBP-3 levels were determined by the Enzyme-Linked Immunosorbent Assay (ELISA) method. RESULT: Median serum IGFBP-3 levels in malnourished children were found to be lower i.e. 0.35mcg/mL (minimum-maximum: 0.04-1.52mcg/mL) compared to well-nourished children 1.52ng/mL (minimum-maximum 0.47-3.17mcg/mL). CONCLUSION: Serum IGFBP-3 levels can be used as indicators to assess nutritional status.
Subject(s)
Child Nutrition Disorders , Insulin-Like Growth Factor Binding Protein 3/blood , Malnutrition , Body Height , Child , Child Nutrition Disorders/epidemiology , Child, Preschool , Cross-Sectional Studies , Humans , Malnutrition/epidemiology , Nutritional StatusABSTRACT
OBJECTIVE: This study aimed to compare serum levels of Growth Hormone in children with malnutrition and good nutritional status. METHOD: This cross-sectional study included 41 participants consisting of 31 malnourished, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. GH levels were determined by the Enzyme-Linked Immunosorbent Assay (ELISA) method. RESULT: Median serum GH levels in malnourished children were found to be lower i.e. 1.25ng/mL (minimum-maximum: 0.10-6.19ng/mL) compared to well-nourished children 11.01ng/mL (1.72-15.64ng/mL). CONCLUSION: Serum GH levels can be used as indicators to assess nutritional status.
Subject(s)
Child Nutrition Disorders , Growth Hormone/blood , Malnutrition , Body Weight , Child , Child Nutrition Disorders/epidemiology , Child, Preschool , Cross-Sectional Studies , Humans , Malnutrition/epidemiology , Nutritional StatusABSTRACT
Objective: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status. Method: This cross-sectional study included 41 participants consisting of 31 malnourished, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. IGFBP-3 levels were determined by the Enzyme-Linked Immunosorbent Assay (ELISA) method. Result: Median serum IGFBP-3 levels in malnourished children were found to be lower i.e. 0.35 mcg/mL (minimummaximum: 0.041.52 mcg/mL) compared to well-nourished children 1.52 ng/mL (minimummaximum 0.473.17 mcg/mL). Conclusion: Serum IGFBP-3 levels can be used as indicators to assess nutritional status. (AU)
Subject(s)
Humans , Male , Female , Child, Preschool , Malnutrition/epidemiology , Child Nutrition Disorders/epidemiology , Insulin-Like Growth Factor Binding Protein 3/blood , Cross-Sectional Studies , Body Weight , Nutritional Status , IndonesiaABSTRACT
Objective: This study aimed to compare serum levels of Growth Hormone in children with malnutrition and good nutritional status. Method: This cross-sectional study included 41 participants consisting of 31 malnourished, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. GH levels were determined by the Enzyme-Linked Immunosorbent Assay (ELISA) method. Result: Median serum GH levels in malnourished children were found to be lower i.e. 1.25 ng/mL (minimummaximum: 0.106.19 ng/mL) compared to well-nourished children 11.01 ng/mL (1.7215.64 ng/mL). Conclusion: Serum GH levels can be used as indicators to assess nutritional status. (AU)