[Translated article] Influence of lateralized reverse shoulder prosthesis design on tuberosity union in proximal humerus fractures.

INTRODUCTION: Proximal humerus fractures are the third most frequent type of fracture in elderly patients. Nowadays, surgical treatment is indicated one third of the time, being the reverse shoulder prosthesis an option especially in complex comminuted patterns. In this study we analyzed the effects of a lateralized reverse prosthesis in tuberosity union and its relationship with the functional results. MATERIAL AND METHODS: Retrospective case study of patients with proximal humerus fractures treated with a lateralized design reverse shoulder prosthesis with one-year minimum follow-up. Tuberosity nonunion was defined as a radiological concept: absence of tuberosity, distance >1cm from the tuberosity fragment to the humeral shaft or tuberosity above the humeral tray. Subgroup analysis was performed, group 1 (n=16) tuberosity union vs. group 2 (n=19) tuberosity nonunion. Groups were compared with the following functional scores: Constant, American Shoulder and Elbow Surgeons and Subjective Shoulder Value. RESULTS: A total of 35 patients were included in this study with a median age of 72.65 years. Postoperative radiographic analysis at one year after surgery revealed a tuberosity nonunion rate of 54%. Subgroup analysis revealed no statistically significant differences in terms of range of motion or functional scores. However, there were differences regarding the Patte sign (p=0.03) which was positive in a larger proportion of patients in the group with tuberosity nonunion. CONCLUSION: Even though there was a large percentage of tuberosity nonunion with the use of a lateralized prosthesis design, patients obtained good results in a similar manner to those found in the union group in terms of range of motion, scores, and patient satisfaction.

Influence of lateralized reverse shoulder prosthesis design on tuberosity union in proximal humerus fractures. / Influencia de las prótesis inversas con diseño lateralizado en la consolidación de las tuberosidades en fracturas de húmero proximal.

INTRODUCTION: Proximal humerus fractures are the third most frequent type of fracture in elderly patients. Nowadays, surgical treatment is indicated one third of the time, being the reverse shoulder prosthesis an option especially in complex comminuted patterns. In this study we analyzed the effects of a lateralized reverse prosthesis in tuberosity union and its relationship with the functional results. MATERIAL AND METHODS: Retrospective case study of patients with proximal humerus fractures treated with a lateralized design reverse shoulder prosthesis with one-year minimum follow-up. Tuberosity nonunion was defined as a radiological concept: absence of tuberosity, distance>1cm from the tuberosity fragment to the humeral shaft or tuberosity above the humeral tray. Subgroup analysis was performed, group 1 (n=16) tuberosity union vs. group 2 (n=19) tuberosity nonunion. Groups were compared with the following functional scores: Constant, American Shoulder and Elbow Surgeons and Subjective Shoulder Value. RESULTS: A total of 35 patients were included in this study with a median age of 72.65 years. Postoperative radiographic analysis at one year after surgery revealed a tuberosity nonunion rate of 54%. Subgroup analysis revealed no statistically significant differences in terms of range of motion or functional scores. However, there were differences regarding the Patte sign (p=0.03) which was positive in a larger proportion of patients in the group with tuberosity nonunion. CONCLUSION: Even though there was a large percentage of tuberosity nonunion with the use of a lateralized prosthesis design, patients obtained good results in a similar manner to those found in the union group in terms of range of motion, scores, and patient satisfaction.

Reverse shoulder arthroplasty in 3 and 4 part proximal humeral fractures in patients aged more than 65 years: Results and complications. / Tratamiento de las fracturas de húmero proximal en pacientes mayores de 65 años con prótesis inversa: resultados y complicaciones.

INTRODUCTION: The treatment of 3and 4 part proximal humeral fractures in elderly patients is still controversial. The frequent co-existence of poor quality bone and rotator cuff abnormalities in patients with multiple clinical conditions and with difficulties for physical rehabilitation leads to disappointing clinical results, even when the radiological images are acceptable. OBJECTIVE: To evaluate the clinical, radiological, and functional results in patients over 65 years old with complex proximal humerus fractures treated with reverse shoulder arthroplasty. MATERIAL AND METHODS: A prospective review was carried out on 30 patients (26 women and 4 men) with proximal humeral fractures treated with reverse shoulder arthroplasty in our department. The mean age was 74.9 years (SD=6.3), and the mean follow-up was 34.5 months (SD=19.3). RESULTS: Clinical and functional results were acceptable, with a mean forward flexion of 124° and a mean external rotation of 13°. The mean abbreviated Constant abbreviated score was 49.1 (SD=14.1), 27 (SD=6.3) in the UCLA scale, and 32.2 (SD=19.2) in the QuickDASH questionnaire. The large majority (80%) of the patients are pain free, and they do not need medication to do daily activities. The complication rate was 13.3%. CONCLUSIONS: We consider that reverse shoulder arthroplasty is a valid option to treat 3and 4 part proximal humeral fractures in elderly patients. The surgical goals should include the anatomical reconstruction of the tuberosities, avoiding enlargement of the operated arm greater than 2cm.

Significance of tuber size for complications of tuberous sclerosis complex.

INTRODUCTION: Tuberous sclerosis complex (TSC) is one of the most frequent neurocutaneous disorders. Cortical tubers are the most common pathological changes in TSC and they are directly related to the disease's main clinical manifestations: seizures, mental retardation, and autistic behaviour. OBJECTIVE: The aim of this study is to establish a correlation between tuber size and the severity of clinical features in TSC. MATERIAL AND METHODS: We performed a retrospective study of the clinical and imaging findings from 45 TSC patients (22 females and 23 males) and compared the clinical features with the location, size, and number of the cortical tubers in each patient. RESULTS: Four patients had voluminous tubers located in 1 or both cerebral hemispheres. All of these patients had intractable seizures and severe mental retardation; 3 of these cases also presented with autistic behaviour, despite tubers having been resected in all 4 patients. Thirteen patients had tubers of large-to-average size, and all patients in this group showed intractable seizures and mental retardation. Nine patients who had experienced infantile spasms during the first year of life presented autistic behaviour. Multiple tubers of small to average size were found in 28 patients. In general, this group had seizures that responded well to antiepileptic drugs and a low prevalence of autism. In 3 patients who all presented good seizure control and normal intelligence, single cortical/subcortical tubers were located in the frontal or occipital lobes. Of the total of 45 patients, 13 had cerebellar as well as cerebral tubers; these were generally present in cases with more severe clinical features. CONCLUSIONS: Although large tubers are less common than small to medium-sized ones, they are much more likely to be accompanied by severe clinical symptoms (seizures, mental retardation and autistic behaviour), even when the smaller tubers are quite numerous.

Fijación de tuberosidades en hemiartroplastía de hombro: descripción y comparación de dos técnicas / Tuberosity fixation in shoulder hemiartroplasty: technique comparison

Introduction: The results in shoulder fracture hemiartroplasty´s, or fracture dislocation, have been traditionally no predictable. These have been related to difficulty in obtaining a suitable consolidation of the tuberosities. On the other hand, reconstruction with more anatomical fixation have improved the functional results. The purpose of our study is to describe, and analyze, the functional and radiological results of two different techniques of tuberosities fixation in shoulder hemiartroplasty. Material and Methods: Between March of 1996 and December 2005, 47 patients (47 shoulders) underwent hemiarthroplasty by 3- and 4- part displaced proximal humerus fracture, or fracture dislocation. We performed in 29cases (61.7 percent) trans tuberosities sutures technique (group I), and in 18 (38.3 percent) independents sutures technique (group II). The average age and sex distribution, was similar between both groups. Constant score and radiological parameters, as head tuberosity distance (HTD) and consolidation of the tuberosities, were analyzed. Statistical analysis was done with ANOVA and Fischer exact test. P values of less than 0.05 were considered statistical significant. Results: Constant Score revealed a difference in favor to group II (66.2 versus 72.8 points; p = 0,1).Radiographic parameters, showed significant differences in favor of the group II (HTD 16.5 vs 8 mm; and 68 percent versus 100 percent consolidation respectively; p < 0,05). Conclusion: According to our results, and in concordance with international literature, tuberosities fixation with independent sutures allow better consolidation, with smaller superior migration, improving the final functional results.

Los resultados de la hemiartroplastía en fracturas o luxo fracturas de hombro, tradicionalmente han sido poco predecibles. Estos se han relacionado a la dificultad en conseguir una adecuada consolidación de las tuberosidades. Por otra parte, la reconstrucción y fijación más anatómica de éstas, ha permitido mejorar sus resultados funcionales. El objetivo de nuestro estudio es describir, y analizar, los resultados funcionales y radiológicos, de dos técnicas de fijación de las tuberosidades en la hemiartroplastía de hombro. Material y Métodos: Entre marzo de 1996 y diciembre de 2005, 47 pacientes (47 hombros) con diagnóstico de fractura de húmero proximal, o luxo fracturas, en 3 ó 4 partes, fueron tratados con prótesis parcial. Se realizó en 29 casos (61,7 por ciento), la técnica de amarras trans tuberositaria (grupo I), y en 18 (38,3 por ciento) la de amarras independientes a modo de cerclaje (grupo II). La edad promedio y sexo, fueron similares entre ambos grupos. Se analizaron variables como score de Constant, y parámetros radiológicos, como la distancia tuberosidad cabeza humeral (HTD), y la presencia de consolidación de las tuberosidades. El análisis estadístico fue hecho con los tests de ANOVA y exacto de Fisher. Los valores p < 0,05 fueron considerados estadísticamente significativos. Resultados: El score de Constant, presentó una diferencia en favor del grupo II, la que no fue significativa (66,2 vs 72,8 puntos; p = 0,1). Los parámetros radiográficos sí mostraron diferencias significativas, a favor del grupo II (HTD 16,5 vs 8 mm; y 68 por ciento vs 100 por ciento consolidación respectivamente; p < 0,05). Conclusión: De acuerdo a nuestros resultados, y en concordancia con la literatura internacional, la fijación de tuberosidades con amarras independientes permite una mejor consolidación, y menor migración superior, lo que permite mejorar los resultados funcionales.

Esclerosis tuberosa: revisión de un caso / Tuberous sclerosis: case report

La esclerosis tuberosa (E.T.) es una enfermedad multisistémica, que consiste en un trastorno de la diferenciación y proliferación celular. Puede afectar a cerebro, piel, corazón, ojos, riñones y otros órganos, originando manifestaciones clínicas diversas.Es la segunda en frecuencia de las facomatosis, superada únicamente por la neurofibromatosis; se calcula su prevalencia entre 10 y 14 por cada 100.000 personas.Presentamos el caso de un niño de 4 meses con manifestaciones cerebrales, dermatológicas, cardiacas y renales enmarcadas en los criterios diagnósticos de esclerosis tuberosa.

Tuberous sclerosis (TS) is a multisystemic illness, which consists on a dysfunction of the differentiation and cellular proliferation. It can affect the brain, the skin, the heart, the eyes, the kidney and other organs, and originate diverse clinical manifestations.It is the second in frequency of the facomatosis, only overcome by the neurofibromatosis, it’s calculated prevalence ranges between 10 to 14 for each 100.000 people.We present the case of 4 months old boy with brain, dermatological, cardiac and renal manifestations, framed in the diagnostic approaches of tuberous sclerosis.