Coordination of joint movement during gait in knee osteoarthritis: Insights from uncontrolled manifold analysis.

This study investigated the covariate structure of each segmental angle that stabilize the center of mass (COM) in the mediolateral and vertical directions in response to knee joint movement in individuals with knee osteoarthritis (KOA) using uncontrolled manifold (UCM) analysis. Twenty individuals with KOA and 13 healthy controls participated in this cross-sectional study. Kinematic and kinetic data were collected during level walking. UCM analysis was used to determine the covariance structure of segment angles stabilizing the COM in the mediolateral and vertical directions. The results indicated reduced knee flexion movement during the stance phase in the KOA group. In the mediolateral direction, the KOA group exhibited increased kinematic synergy stabilizing the COM. However, in the vertical direction, decreased kinematic synergy was observed. KOA group demonstrated greater trial-to-trial variances in segmental angles constituting the knee joint, suggesting enhanced covariance structure attempting to stabilize the COM in the mediolateral direction but increasing variability that destabilizes the COM in the vertical direction. Furthermore, decreased knee flexion movement during loading response may lead to reduced vertical kinematic synergy. In conclusion, these findings underscore the need to address improving knee flexion movement during the loading response to prevent osteoarthritis progression in patients with KOA. It provides insights into interventions focusing on improving knee flexion and enhancing kinematic synergy in the vertical direction, potentially benefiting patients with KOA.

Human movement strategies in uncertain environments: A synergy-based approach to the stability-agility tradeoff.

Humans frequently prepare for agile movements by decreasing stability. This facilitates transitions between movements but increases vulnerability to external disruptions. Therefore, humans might weigh the risk of disruption against the gain in agility and scale their stability to the likelihood of having to perform an agility-demanding action. We used the theory of motor synergies to investigate how humans manage this stability-agility tradeoff under uncertainty. This theory has long quantified stability using the synergy index, and reduction in stability before movement transitions using anticipatory synergy adjustment (ASA). However, the impact of uncertainty - whether a quick action should be executed or inhibited - on ASA is unknown. Furthermore, the impact of ASA on execution and inhibition of the action is unclear. We combined multi-finger, isometric force production with the go/no-go paradigm. Thirty participants performed constant force (no-go task), rapid force pulse (go task), and randomized go and no-go trials (go/no-go task) in response to visual cues. We measured the pre-cue finger forces and computed ASA using the uncontrolled manifold method and quantified the spatio-temporal features of the force after the visual cue. We expected ASA in both go/no-go and go tasks, but larger ASA for the latter. Surprisingly, we observed ASA only for the go task. For the go/no-go task, 53% of participants increased stability before the cue. The high stability hindered performance, leading to increased errors in no-go trials and lower peak forces in go trials. These results align with the stability-agility tradeoff. It is puzzling why some participants increased stability even though 80% of the trials demanded agility. This study indicates that individual differences in the effect of task uncertainty and motor inhibition on ASA is unexplored in motor synergy theory and presents a method for further development.

Longitudinal Alterations in the Control of Lateral Center of Mass Movement During Walking in a Patient With Unilateral Transtibial Amputation: A Case Study.

This study assessed longitudinal changes in the control of the center of mass (CoM) in the lateral direction through gait reacquisition in an individual with unilateral transtibial amputation (UTTA). We examined a male patient with UTTA who could walk on a parallel bar. The marker trajectories and ground reaction forces were measured every two weeks (total: four times) using an optical motion capture system and force plates. After two measurements, the samples were collected without a parallel bar. Subsequently, we evaluated the CoM movement and its segmental coordination through uncontrolled manifold (UCM) analysis. After the second measurement, the walking speed and step length increased. The lateral CoM movements gradually increased toward the prosthetic side until the third measurement. In the fourth measurement, the CoM movement towards the prosthetic side was the smallest and closest to the intact side at the end of the stance phase. In addition, segmental coordination improved significantly. Enhanced gait performance delayed the improvement of segmental coordination for CoM movement in the lateral direction.

Three Levels of Neural Control Contributing to Performance-stabilizing Synergies in Multi-finger Tasks.

We tested a hypothesis on force-stabilizing synergies during four-finger accurate force production at three levels: (1) The level of the reciprocal and coactivation commands, estimated as the referent coordinate and apparent stiffness of all four fingers combined; (2) The level of individual finger forces; and (3) The level of firing of individual motor units (MU). Young, healthy participants performed accurate four-finger force production at a comfortable, non-fatiguing level under visual feedback on the total force magnitude. Mechanical reflections of the reciprocal and coactivation commands were estimated using small, smooth finger perturbations applied by the "inverse piano" device. Firing frequencies of motor units in the flexor digitorum superficialis (FDS) and extensor digitorum communis (EDC) were estimated using surface recording. Principal component analysis was used to identify robust MU groups (MU-modes) with parallel changes in the firing frequency. The framework of the uncontrolled manifold hypothesis was used to compute synergy indices in the spaces of referent coordinate and apparent stiffness, finger forces, and MU-mode magnitudes. Force-stabilizing synergies were seen at all three levels. They were present in the MU-mode spaces defined for MUs in FDS, in EDC, and pooled over both muscles. No effects of hand dominance were seen. The synergy indices defined at different levels of analysis showed no correlations across the participants. The findings are interpreted within the theory of control with spatial referent coordinates for the effectors. We conclude that force stabilization gets contributions from three levels of neural control, likely associated with cortical, subcortical, and spinal circuitry.

The Amount and Pattern of Reciprocal Compensations Predict Performance Stability in a Visually Guided Finger Force Production Task.

Previous work suggests that synergistic activity among motor elements implicated in force production tasks underlies enhanced performance stability associated with visual feedback. A hallmark of synergistic activity is reciprocal compensation, that is, covariation in the states of motor elements that stabilizes critical performance variables. The present study examined if characteristics of reciprocal compensation are indicators of individuals' capacity to respond adaptively to variations in the resolution of visual feedback about criterion performance. Twenty healthy adults (19.25 ± 1.25 years; 15 females and five males) pressed two sensors with their index fingers to produce a total target force equivalent to 20% of their maximal voluntary contraction under nine conditions that differed in the spatial resolution of real-time feedback about their performance. By combining within-trial uncontrolled manifold and sample entropy analyses, we quantified the amount and degree of irregularity (i.e., non-repetitiveness) of reciprocal compensations over time. We found a U-shaped relationship between performance stability and gain. Importantly, this relationship was moderated by the degree of irregularity of reciprocal compensation. Lower irregularity in reciprocal compensation patterns was related to individuals' capacity to maintain (or minimize losses in) performance under changes in feedback resolution. Results invite future investigation into how interindividual variations in reciprocal compensation patterns relate to differences in control strategies supporting adaptive responses in complex, visually guided motor tasks.

Quantifying Changes in Dexterity as a Result of Piano Training in People with Parkinson's Disease.

People with Parkinson's disease often show deficits in dexterity, which, in turn, can lead to limitations in performing activities of daily life. Previous studies have suggested that training in playing the piano may improve or prevent a decline in dexterity in this population. In this pilot study, we tested three participants on a six-week, custom, piano-based training protocol, and quantified dexterity before and after the intervention using a sensor-enabled version of the nine-hole peg test, the box and block test, a test of finger synergies using unidimensional force sensors, and the Quantitative Digitography test using a digital piano, as well as selected relevant items from the motor parts of the MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) and the Parkinson's Disease Questionnaire (PDQ-39) quality of life questionnaire. The participants showed improved dexterity following the training program in several of the measures used. This pilot study proposes measures that can track changes in dexterity as a result of practice in people with Parkinson's disease and describes a potential protocol that needs to be tested in a larger cohort.

The effect of motor experience on knee stability and inter-joint coordination when cutting at different angles.

BACKGROUND: Most studies on cutting have focused on the biomechanics of the knee and lower-limb muscle activation characteristics, with less consideration given to the influence of motor experience on control strategies at the joint level. This study aimed to investigate the differences in knee stability and inter-joint coordination between high- and low-level athletes when cutting at different angles. METHODS: A Vicon motion capture system and a Kistler force table were used to obtain kinematic and ground reaction force data during cutting. Joint dynamic stiffness and vector coding were used to assess knee stability and inter-joint coordination. Uncontrolled manifold analysis was used to clarify whether there was synergy among lower-limb joints to maintain postural stability during cutting. RESULTS: During the load acceptance phase, skilled subjects had the smallest joint stiffness at 90° compared with novice subjects (P < 0.05). Compared with novice subjects, skilled subjects had smaller knee-hip ellipse areas at 90° and 135° (P < 0.05), but larger knee-ankle ellipse areas at 135° (P < 0.05). The synergy index in load acceptance was significantly higher (P < 0.05) for skilled subjects at 90° and 135°. CONCLUSIONS: Advanced subjects can adjust joint control strategies to adapt to the demands of large-angle cutting on the change of direction. Advanced subjects can reduce knee stability for greater flexibility during cutting compared with novice subjects. By increasing the degree of synergy among the lower-limb joints, advanced athletes can maintain high postural stability.

Motor flexibility to stabilize the toe position during obstacle crossing in older adults: an investigation using an uncontrolled manifold analysis.

Introduction: An age-related decrease in the ability to exploit the abundant degrees of freedom of the body, referred to as motor flexibility, leads to a heightened fall risk. The present study investigated motor flexibility to stabilize the toe position during obstacle crossing in older adults and its correlation with the magnitude of foot elevation. Methods: Twenty-six older adults (70.9 ± 7.4 years old) and 21 younger adults (25.4 ± 5.0 years old) walked and crossed an obstacle, during which the dominant limb was always the leading limb. An uncontrolled manifold (UCM) analysis was used to quantify the flexibility during obstacle crossing as the synergy index, with the vertical toe position being regarded as the performance variable and the segment angles of the lower limbs as the elemental variables. Results and discussion: The results showed that older participants had a significantly lower synergy index for the trailing limb before the moment of obstacle crossing than younger participants, suggesting reduced flexibility in part. The results also showed that, regardless of age, foot elevation was negatively correlated with the synergy index, suggesting that a so-called "conservative strategy" (i.e., a tendency to show extraordinarily high foot elevation to ensure collision avoidance) may be related to their reduced motor flexibility.

An analysis of the effect of motor experience on muscle synergy in the badminton jump smash.

The jump smash is badminton's most aggressive technical manoeuvre, which is often the key to winning a match. This paper aims to explore the neuromuscular control strategies of advanced and beginner players when jumping smash in different ways. Collecting sEMG and kinematic data from 18 subjects with different motor experiences when jumping smash. Nonnegative Matrix Factorization and K-Means clustering were used to extract muscle synergies and exclude irrelevant combined synergies. Uncontrolled manifold analysis was then used to explore the association between synergies and shoulder stability. In addition, motor output at the spinal cord level was assessed by mapping sEMG to each spinal cord segment. The study found that advanced subjects could respond to different jump smash styles by adjusting the coordinated activation strategies of the upper-limb and postural muscles. Long-term training can induce a rapid decrease in the degree of co-variation of the synergies before contact with a shuttlecock to better cope with an upcoming collision. It is recommended that beginners should focus more on training the coordination of upper-limb muscles and postural muscles.

Effects of visual feedback and force level on bilateral ankle-dorsiflexion force control.

This study investigated the potential effects of visual feedback and force level on bilateral force control capabilities in the lower limbs. Thirty-nine healthy young adults performed bilateral ankle-dorsiflexion isometric force control tasks for different visual feedback conditions, including continuous visual feedback (CVF) and withdrawal of visual feedback (WVF), indicating the removal of visual feedback on force outputs during the task and force level conditions (i.e., 10 % and 40 % of the maximum voluntary contraction). Bilateral force control capabilities were estimated using force accuracy, variability, regularity, and absolute power in 0-4 Hz and interlimb coordination by cross-correlation with time lag and uncontrolled manifold (UCM) variables. Correlation analyses determined the relationship between changes in bilateral force control capabilities and interlimb coordination from the CVF to WVF conditions. The findings revealed better bilateral force control capabilities in the CVF condition as indicated by less force error, variability, regularity, absolute power in 0-4 Hz, and advanced interlimb force coordination. From CVF to WVF conditions, increased bad variability correlated with greater force control deficits. These findings suggest that visuomotor processing is an important resource for successful fine motor control in the lower limbs.

Variability of Postural Coordination in Dual-Task Paradigm.

Postural control is influenced by cognition. In most studies, variability of motor output has been considered regardless of variability in patterns of joint coordination. Uncontrolled manifold framework has been applied to decompose the joint's variance in two components. The first component leaves position of the center of mass in anterior-posterior direction (CoMAP) unchanged (VUCM) while the second component is in charge of variations of CoM (VORT). In this study, 30 healthy young volunteers were recruited. The experimental protocol consisted of three random conditions: quiet standing on a narrow wooden block without a cognitive task (NB), quiet standing on a narrow wooden block with an easy cognitive task (NBE), and quiet standing on a narrow wooden block with a difficult cognitive task (NBD). Results showed that CoMAP sway in NB condition was higher than both NBE and NBD conditions (p = .001). VORT in NB condition was higher than NBE and NBD conditions (p = .003). VORT in NB condition was higher than NBE and NBD conditions (p = .003). VUCM was unchanged in all conditions (p = 1.00) and synergy index in NB condition was smaller than NBE and NBD conditions (p = .006). These results showed that postural synergies increased under dual-task conditions.

Characteristics of muscle synergy and anticipatory synergy adjustments strategy when cutting in different angles.

BACKGROUND: Cutting is a quick change of direction that challenges body balance and stability. As the cut-angle increases, the elite athlete can achieve higher performance by pre-adjusting the posture of the lower limb joints. However, it is unclear how the cut-angle affects the neuromuscular control of cutting and the step before cutting, which is essential for daily training and preventing injury in large-angle cutting. RESEARCH QUESTION: The purpose of this study was to determine how neuromuscular control strategies change under different angles for cutting and the step before cutting METHODS: Non-negative matrix factorisation and K-means clustering were used to extract muscle synergy in the trunk and lower limbs of 12 athletes when cutting at different angles. Uncontrolled manifold analysis was used to clarify whether the muscle synergy fluctuations in the step before cutting were beneficial in stabilising the COP during the cutting. RESULTS: This study found that the angle did not affect the number of muscle synergies either in the cutting or the step before the cutting. As the angle increases, the activation timing of synergy module 2 during cutting moves forward and is tightly integrated with module 1. The combined synergy at 90° accounted for the largest proportion of either cutting or the step before cutting and had a lower synergy index. SIGNIFICANCE: Muscle synergy can respond to large-angle cutting through flexible combinations. The muscle synergy for 90° cutting is less regular and has a lower degree of anticipatory synergy adjustments, which may result in poorer postural stability and an increased risk of lower limb joint injury during cutting.

Neuromechanical stabilisation of the centre of mass during running.

BACKGROUND: Stabilisation of the centre of mass (COM) trajectory is thought to be important during running. There is emerging evidence of the importance of leg length and angle regulation during running, which could contribute to stability in the COM trajectory The present study aimed to understand if leg length and angle stabilises the vertical and anterior-posterior (AP) COM displacements, and if the stability alters with running speeds. METHODS: Data for this study came from an open-source treadmill running dataset (n = 28). Leg length (m) was calculated by taking the resultant distance of the two-dimensional sagittal plane leg vector (from pelvis segment to centre of pressure). Leg angle was defined by the angle subtended between the leg vector and the horizontal surface. Leg length and angle were scaled to a standard deviation of one. Uncontrolled manifold analysis (UCM) was used to provide an index of motor abundance (IMA) in the stabilisation of the vertical and AP COM displacement. RESULTS: IMAAP and IMAvertical were largely destabilising and always stabilising, respectively. As speed increased, the peak destabilising effect on IMAAP increased from -0.66(0.18) at 2.5 m/s to -1.12(0.18) at 4.5 m/s, and the peak stabilising effect on IMAvertical increased from 0.69 (0.19) at 2.5 m/s to 1.18 (0.18) at 4.5 m/s. CONCLUSION: Two simple parameters from a simple spring-mass model, leg length and angle, can explain the control behind running. The variability in leg length and angle helped stabilise the vertical COM, whilst maintaining constant running speed may rely more on inter-limb variation to adjust the horizontal COM accelerations.

Advanced Force Coordination of Lower Extremities During Visuomotor Control Task in Soccer Players.

Purpose: This study is aimed to determine specific bilateral lower extremity motor performances and coordination patterns in soccer players with healthy controls using the bilateral force control paradigm. We hypothesized that soccer players would show more advanced bilateral force control performances than untrained controls. Methods: Participants were 13 university soccer players and 13 healthy controls. Each group performed bilateral ankle dorsiflexion force control tasks across two vision conditions (i.e., vision and no-vision) and two targeted force levels (i.e., 10% and 40% maximum voluntary contraction). We calculated force accuracy, variability, and symmetry to assess force control performances. To estimate bilateral force coordination, we calculated Pearson's correlation coefficients between feet-within a single trial and considered uncontrolled manifold variables across multiple trials. In the no-vision condition, we performed secondary analyses for initial force control patters after removal of visual feedback. Results: There were no significant group differences in bilateral force accuracy and variability but, compared to the control group, soccer players showed higher force symmetry between left and right ankle dorsiflexion forces. For force coordination between feet, soccer players revealed more negative values of the correlation coefficient and greater good variability from the uncontrolled manifold analysis than those for the control group. The secondary analysis revealed no significant group differences in the time until force drift and amount of force adjustments. Conclusions: Soccer players have more compensatory and flexible interlimb force coordination strategies between feet.

A long short-term memory modeling-based compensation method for muscle synergy.

Muscle synergy containing temporal and spatial patterns of muscle activity has been frequently used in prediction of kinematic characteristics. However, there is often some discrepancy between the predicted results based on muscle synergy and the actual movement performance. This study aims to propose a new method for compensating muscle synergy that allows the compensated synergy signal to predict kinematic characteristics more accurately. The study used the change of direction in running as background. Non-negative matrix factorisation was used to extract the muscle synergy during the change of direction at different angles. A non-linear association between synergy and the height of pelvic mass centre was established using long and short-term memory neural networks. Based on this model, the height fluctuations of the pelvic centre of mass are used as input and predict the fluctuations of the synergy which were used to compensate for the original synergy in different ways. The accuracy of the synergies compensated in different ways in predicting pelvic centre of mass movement was then assessed by back propagation neural networks. It was found that the compensated synergy significantly improves accuracy in predicting pelvic centre of mass displacement (R2, p < 0.05). The predicted results of all-compensation are significantly different from actual performance in the end-swing (p < 0.05). The predicted results of half-compensation do not differ significantly from the actual performance, and its damage to the original synergy is smaller and does not increase with angle compared to all-compensation. The all-compensation may be affected by individual variability and lead to increased errors. The half-compensation can improve the predictive accuracy of the synergy while reducing the adjustment to the original synergy.

Experience influences kinematic motor synergies: an Uncontrolled manifold approach to simulated Nordic skiing.

Motor synergies are defined as central nervous system mechanisms which adjust participating degrees of freedom to ensure dynamic stability (control) of certain performance variables and have been identified during many motor tasks. The potential for synergistic control of individual segments during full-body tasks is often overlooked. Thus, this study compared individual differences in the potential stabilization of multiple performance variables on the basis of experience during a full-body sport activity. Normalized time series of synergy indices from Uncontrolled Manifold analyses on experienced (n = 9) and inexperienced (n = 19) participants were analysed using statistical parametric mapping during simulated Nordic skiing. Regardless of experience, hand, upper arm, and whole-body centre of mass (COM) kinematics were found to be stabilized by kinematic motor synergies. Only experienced Nordic skiers stabilized trunk COM position at all, while trunk COM velocity was stabilized for a longer duration than inexperienced participants. However, inexperienced participants stabilized hand velocity for a greater duration overall and to a greater magnitude during early pull phase than the experienced skiers. That motor synergies for hand and trunk COM velocity differed between experience groups suggests potential utility for these performance variables as indicators of motor skill development for full-body tasks such as Nordic skiing.

The Influence of Experience on Neuromuscular Control of the Body When Cutting at Different Angles.

Cutting is an offensive technique commonly used in football and basketball to pass the opponent's defence by changing direction quickly in running. This paper aims to investigate the effect of experience and angle on the neuromuscular control strategies of the trunk and lower limbs during cutting. Non-negative matrix factorisation and K-means were used to extract muscle synergies (muscles that are activated in parallel) of 12 subjects with cut experience and 9 subjects without experience based on the sEMG signal collected from cutting at three cut angles (45°, 90°, and 135°), which was also mapped into the spinal motor output. Uncontrolled manifold analysis was used to establish the relationship between muscle synergies and COP. This study found that experienced subjects tended to use the lower limb muscles rather than the postural muscles as stabiliser muscles compared to novices. Experienced subjects can recruit an additional set of muscle synergy to cope with large-angle cuts. In addition, experienced subjects can activate the second muscle synergy, involving the hip and ankle stabilisation muscles, in advance to improve postural stability when cutting in large-angle. Synergy index of experienced subjects dropped rapidly before the quick stop and was relatively high during the change of direction. These results suggest that experience can modify the postural stabilisation mechanisms during cutting, and prompt the lower limb muscle synergy to produce anticipatory adjustment to improve postural stability in the anterior-posterior and internal-external directions.

Attentional focus effects on joint covariation in a reaching task.

Adopting an external focus of attention (EF) has been found beneficial over internal focus (IF) for performing motor skills. Previous studies primarily examined focus of attention (FOA) effects on performance outcomes (such as error and accuracy), with relatively less emphasis on movement coordination. Given that human movements are kinematically and kinetically abundant (Gefland & Latash, 1998), FOA instructions may change how motor abundance is utilized by the CNS. This study applied the uncontrolled manifold analysis (UCM) to address this question in a reaching task. Healthy young adults (N = 38; 22 ± 1 yr; 7 men, 31 women) performed planar reaching movements to a target using either the dominant or nondominant arm under two different FOA instructions: EF and IF. Reaching was performed without online visual feedback and at a preferred pace. Joint angles of the clavicle-scapula, shoulder, elbow, and wrist were recorded, and their covariation for controlling dowel endpoint position was analyzed via UCM. As expected, IF led to a higher mean radial error than EF, driven by increases in aiming bias and variability. Consistent with this result, the UCM analysis showed that IF led to higher goal-relevant variance among the joints (VORT) compared to EF starting from the first 20% of the reach to the end. However, the goal-irrelevant variance (VUCM)-index of joint variance that does not affect the end-effector position-did not show FOA effects. The index of stability of joint coordination with respect to endpoint position (ΔV) was also not different between the EF and IF. Consistent with the constrained action hypothesis, these results provide evidence that IF disrupted goal-relevant joint covariation starting in the early phases of the reach without affecting goal-irrelevant coordination.

Time profile of kinematic synergies of stroke gait.

BACKGROUND: In stroke subjects, the motor skills differ between sides and among subjects with different levels of motor recovery, impacting inter-joint coordination. How these factors can affect the kinematic synergies over time during gait has not been investigated yet. This work aimed to determine the time profile of kinematic synergies of stroke patients throughout the single support phase of gait. METHODS: Kinematic data from 17 stroke and 11 healthy individuals was recorded using a Vicon System. The Uncontrolled Manifold approach was employed to determine the distribution of components of variability and the synergy index. To analyze the time profile of kinematic synergies, we applied the statistical parametric mapping method. Comparisons were made within the stroke group (paretic and non-paretic limbs) and between groups (stroke and healthy). The stroke group was also subdivided into subgroups with worse and better motor recovery. FINDINGS: There are significant differences in synergy index at the end of the single support phase between stroke and healthy subjects; paretic and non-paretic limbs; and paretic limb according to the motor recovery. Comparisons of mean values showed significantly larger values of synergy index for the paretic limb compared to the non-paretic and healthy. INTERPRETATION: Despite the sensory-motor deficits and the atypical kinematic behavior, stroke patients can produce joint covariations to control the center of mass trajectory in the forward progression plane, but the modulation of the synergy is impaired, reflecting altered adjustments, especially in the paretic limb of subjects with worse levels of motor recovery.

Influence of aging on the control of the whole-body angular momentum during volitional stepping: An UCM-based analysis.

Evidence suggests that whole-body angular momentum (WBAM) is a highly controlled mechanical variable for performing our daily motor activities safely and efficiently. Recent findings have revealed that, compared to young adults, older adults exhibit larger range of WBAM during various motor tasks, such as walking and stepping. However, it remains unclear whether these age-related changes are ascribed to a poorer control of WBAM with age or not. The purpose of the present study was to examine the effect of normal aging on WBAM control during stepping. Twelve young adults and 14 healthy older adults performed a series of volitional stepping at their preferred selected speed. An Uncontrolled Manifold (UCM) analysis was conducted to explore the presence of synergies among the angular momenta of the body segments (elemental variables) to control WBAM (performance variable); i.e., to stabilize or destabilize it. Results revealed the existence of a stronger synergy destabilizing the WBAM in the sagittal-plane older adults compared to young adults during stepping, while there was no difference between the two groups in the frontal and transversal planes. Although older participants also had a larger range of WBAM in the sagittal plane compared to young adults, we found no significant correlation between synergy index and the range of WBAM in the sagittal plane. We concluded that the age-related changes in WBAM during stepping are not ascribed to alterations in the ability to control this variable with aging.