Curative Effect Observation on Yixin Tongmai Decoction in Prevention and Treatment of Restenosis after Coronary Stenting of Diabetes Mellitus Complicated with Coronary Heart Disease Cases / 世界科学技术-中医药现代化

This study was aimed to evaluate the efficacy and safety of Y ixin Tongmai Decoction in prevention and treatment of diabetes mellitus complicated with coronary heart disease ( CHD ) after coronary stenting restenosis . Sixty cases were randomly divided into the conventional western medicine treatment plus Y ixin Tongmai Decoction group ( treatment group ) and conventional treatment of western medicine group ( control group ) . Observation was given on the in-stent restenosis before treatment and one-year after treatment . And the traditional Chinese medicine ( TCM ) Syndrome Scale , changes of single symptom in TCM syndrome , effect of Y ixin Tongmai Decoction on blood glucose and other adverse reactions were also observed before and one-year after treatment . The results showed that in the curative effect evaluation , the restenosis rate of treatment group was 6 . 90%, and the restenosis rate of control group was 17 . 24%. There was significant difference be-tween two groups ( P < 0 . 05 ) . According to the standard of TCM syndrome curative effect , the total effective-ness in the treatment group was 86 . 21%, and that of the control group was 31 . 03%. And there was signifi-cant difference between two groups ( P < 0 . 05 ) . In the safety evaluation , there were no obvious abnormalities during safety detection in the clinical study of two groups. There was no influence on blood sugar levels. And no drug related adverse reactions occurred . It was concluded that Y ixin Tongmai Decoction can reduce coro-nary stent restenosis rate in diabetes complicated with CHD (chest pain) with the syndrome of qi deficiency and blood stasis , phlegm-turbid stasis . It can significantly improve the TCM syndrome and single symptom of patients with good safety .

Clinical Study of Coronary Heart Disease and Angina Pectoris with Blood Stasis Syndrome Treated by Yixin Tongmai Decoction / 中国中医药信息杂志

Objective To observe the clinical effects of Yixin Tongmai Decoction in treating angina pectoris in CHD (blood stasis syndrome) and explore its mechanism. Methods Sixty patients were randomized into two groups. The treatment group (30 cases) and the contrastive group (30 cases) were respectively given Yixin Tongmai Decoction and Danshen Injection. The clinical and ECG effect, the indexes of hemorrheology were observed. Result Effective rate of treatment group was 90.00%, significantly higher than 70.00% of contrastive group (P