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1.
Eur J Surg Oncol ; 50(1): 107268, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38043361

ABSTRACT

Intestinal lymphomas can rarely present as abdominal catastrophes with perforation or small bowel obstruction. There is little data regarding their optimal surgical management and associated outcomes. We aimed to systematically review relevant published literature to assess the presentation, diagnosis, optimal surgical approach and associated post-operative outcomes. A systematic on-line literature search of Embase and Medline identified 1485 articles of which 34 relevant studies were selected, including 7 retrospective studies, 1 case series and 26 case reports. Selected articles were assessed by two reviewers to extract data. 95 patients with abdominal catastrophes secondary to lymphoma (predominately Burkitt (28 %) and Diffuse Large B-cell lymphoma (29 %)) were identified with a median age of 52 years, 40 % were female. Of the small bowel resections 25% (n = 18) suffered post-operative complications with a 13.8 % (n = 10) 30-day mortality. Ileocolonic resections had a 27 % complication rate with 18 % mortality and primary repair had a 25 % complications rate and 25 % mortality. Median follow-up was 8 days (range 1-96). Notable points of differences in the presentations between these different lymphomas included the majority of Burkitt's lymphoma were younger, had a known diagnosis, were on chemotherapy and presented with perforation in contrast to those with B cell lymphoma who were predominately older, had new diagnoses and presented with a balanced proportion of obstruction and perforation. Abdominal catastrophes secondary to intestinal lymphomas most commonly present with perforation. Aggressive surgical management, including small bowel resection, may offer similar remission rates for lymphoma patients presenting with abdominal catastrophes as those without such emergency complications.


Subject(s)
Burkitt Lymphoma , Intestinal Neoplasms , Intestinal Obstruction , Lymphoma , Humans , Female , Middle Aged , Male , Laparotomy , Retrospective Studies , Lymphoma/complications , Lymphoma/surgery , Burkitt Lymphoma/complications , Burkitt Lymphoma/diagnosis , Burkitt Lymphoma/surgery , Intestinal Obstruction/etiology , Intestinal Obstruction/surgery , Intestinal Neoplasms/complications , Intestinal Neoplasms/surgery
2.
Scand J Surg ; 106(2): 145-151, 2017 Jun.
Article in English | MEDLINE | ID: mdl-27528695

ABSTRACT

BACKGROUND AND AIMS: The open abdomen technique is a standard procedure in the treatment of intra-abdominal catastrophe. Achieving primary abdominal closure within the initial hospitalization is a main objective. This study aimed to analyze the success of closure rate and the effect of negative pressure wound therapy, mesh-mediated medial traction, and component separation on the results. We present the treatment algorithm used in our institution in open abdomen situations based on these findings. MATERIAL AND METHODS: Open abdomen patients (n = 61) treated in Tampere University Hospital from May 2005 until October 2013 were included in the study. Patient characteristics, treatment prior to closure, closure technique, and results were retrospectively collected and analyzed. The first group included patients in whom direct or bridged fascial closure was achieved, and the second group included those in whom only the skin was closed or a free skin graft was used. Background variables and variables related to surgery were compared between groups. RESULTS AND CONCLUSION: Most of the open abdomen patients (72.1%) underwent fascial defect repair during the primary hospitalization, and 70.5% of them underwent direct fascial closure. Negative pressure wound therapy was used as a temporary closure method for 86.9% of the patients. Negative pressure wound therapy combined with mesh-mediated medial traction resulted in the shortest open abdomen time (p = 0.039) and the highest fascial repair rate (p = 0.000) compared to negative pressure wound therapy only or no negative pressure wound therapy. The component separation technique was used for 11 patients; direct fascial closure was achieved in 5 and fascial repair by bridging the defect with mesh was achieved in 6. A total of 8 of 37 (21.6%) patients with mesh repair had a mesh infection. The negative pressure wound therapy combined with mesh-mediated medial traction promotes definitive fascial closure with a high closure rate and a shortened open abdomen time. The component separation technique can be used to facilitate fascial repair but it does not guarantee direct fascial closure in open abdomen patients.


Subject(s)
Abdominal Wall/surgery , Abdominal Wound Closure Techniques , Laparotomy/adverse effects , Negative-Pressure Wound Therapy/methods , Quality Improvement , Adult , Aged , Algorithms , Cohort Studies , Fascia , Female , Follow-Up Studies , Humans , Laparotomy/methods , Male , Middle Aged , Retrospective Studies , Risk Assessment , Surgical Mesh , Time Factors , Treatment Outcome , Wound Healing/physiology
3.
NDT Plus ; 3(6): 549-50, 2010 Dec.
Article in English | MEDLINE | ID: mdl-25949464

ABSTRACT

Severe worsening lactic acidosis in an elderly patient following an episode of atrial fibrillation, who is not haemodynamically compromised, usually indicates an intra-abdominal vascular catastrophe. We describe a unique case of severe peri-renal sepsis in a patient with long-standing dialysis-dependent chronic kidney disease unrelated to urolithiasis that masqueraded as an acute abdominal condition requiring emergency laparotomy and nephrectomy.

4.
Article in English | WPRIM (Western Pacific) | ID: wpr-963464

ABSTRACT

1. A quick differentiation between an abdominal-wall injury and a visceral injury is very important for proper management2. Difficulty in the differentiation can be overcome by an early, close, and constant observation of the patient, the temperature, pulse, and respiration, with frequent red-blood and white-cell and differential counts, hemoglobin percentage, and by aid of the x-ray3. The high mortality rate is due to the fact that these cases were brought to the hospital long after the accident, or, if brought immediately, the injuries were too extensive4. The high mortality demonstrates clearly the challenge to the profession of the serious difficulty in the diagnosis and management of traumatic abdominal catastrophes.(Conclusions)


Subject(s)
Abdomen
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