The Dilemma Of Management Of Cystic Lesions; An Uncertain Way Forward: A Case Report.

Periapical diseases ranges from mild granulomatous lesions to large cystic ones, with the treatments corresponding to their respective pre-operative diagnoses. However, the determination of cause of periapical radiolucency is impossible on pre-operative clinical and radiographic examinations. We present a case highlighting the difficulties encountered in treating a periapical cyst using the current evidence in literature. It demonstrates the uncertainty involved in treating such lesions, owing to the impossible nature of determining the histopathological nature of the cyst, i.e., being either true cysts or pocket cysts. This case includes orthograde re-treatment; decompression of the cystic lesion, followed by peri-apical surgery of two teeth over a course of three years; and the uncertain outcomes encountered after each phase of the treatment.

Diagnosis and treatment of apical cyst of deciduous teeth with infection: a case report.

There is a high incidence of chronic periapical periodontitis of deciduous teeth, however, there is a low incidence of the apical cyst. This paper reports a 7-year-old child with deciduous periodontitis caused by chronic periapical periodontitis of deciduous teeth. Through literature review, the etiology, imaging characteristics, diagnosis, differential diagnosis, and treatment methods were discussed to provide the basis for clinical diagnosis and treatment.

Diagnosis and treatment of apical cyst of deciduous teeth with infection: a case report / 华西口腔医学杂志

There is a high incidence of chronic periapical periodontitis of deciduous teeth, however, there is a low incidence of the apical cyst. This paper reports a 7-year-old child with deciduous periodontitis caused by chronic periapical periodontitis of deciduous teeth. Through literature review, the etiology, imaging characteristics, diagnosis, differential diagnosis, and treatment methods were discussed to provide the basis for clinical diagnosis and treatment.

Treatment of an apical cyst with platelet concentrate - a case report.

Apical cysts are typically caused by dental pulp disease and are difficult to treat. In the majority of cases, surgical intervention is required. The rate of success after apical osteotomy varies between 60% and 91%. The introduction of platelet concentrates in treating chronic apical periodontitis is a promising direction for achieving quick and secure results. This article examines the healing of a sizable apical cyst after conservative surgical intervention and the application of platelet concentrate.

¿Los Quistes Periradiculares Dependen de la Infección Endodóntica?

RESUMEN: Los quistes periradiculares, tanto los de bolsillo como los verdaderos, son de origen inflamatorio; sin embargo, en la literatura ha existido una gran controversia asociada, en primer lugar, a la dependencia de la infección contenida dentro del sistema de conductos radiculares y, en segundo lugar, al tipo de tratamiento endodóntico llevado a cabo en este tipo de lesiones. Con el fin de dilucidar esta controversia se realizará una revisión a la literatura sobre quistes perira diculares donde se explicará cuál es la técnica más adecuada en el diagnóstico de quistes verdaderos y de bolsillo. Igualmente, se explicará la teoría de autosustentabilidad, así como el tratamiento endodóntico de grandes lesiones periradiculares asociadas a dichos quistes. Ahora bien, en la actualidad se ha demostrado que ambos quistes están asociados a infecciones contenidas en el sistema de conductos radiculares y son diferentes solamente en su morfología. Así mismo, se ha recomendado el tratamiento de conducto convencional en dientes con grandes lesiones asociadas a quistes.

ABSTRACT: Radicular cysts, either the pocket or the true cysts, are originated by an inflammation. However, in the literature, there has been great controversy surrounding, firstly, the dependence of the infection contained within the radicular conducts and, secondly, the kind of endodontic treatment performed in this sort of injury. In order to clarify this controversy, the literature concerning radicular cysts will be reviewed and it will be explained what technique is the most appropriate for diagnosing true cysts and pocket cysts. Likewise, the theory of self-sustaining, as well as the endodontic treatment for large radicular injuries associated to such cysts, will be further explained. Nonetheless, nowadays it has been demonstrated that both cysts are associated to infections contained within the system of radicular conducts and that they are only morphologically different. In addition, the root canal treatment has been recommended for teeth with great injuries associated to cysts.

Investigation of the effectiveness of CBCT and gray scale values in the differential diagnosis of apical cysts and granulomas.

PURPOSE: The aim of this study was to investigate the effectiveness of cone-beam CT (CBCT) findings and gray scale values (GSV) in the differential diagnosis of apical cysts and granulomas. METHODS: Two independent researchers retrospectively analyzed the CBCT images of 21 teeth and histopathologically diagnosed them as having radicular cysts or apical granulomas. In the CBCT images, apical lesions were evaluated and categorized according to 7 criteria. These criteria were determined as relationship of lesions with dental roots, periphery of the lesion, shape, darker focus in the center, root resorption, displacement in related teeth, and cortical bone perforation. In addition, the minimum and maximum gray scale values of the lesions were measured and compared. RESULTS: There was a statistically significant relationship between histopathological (HP) diagnosis and well-defined cortical border and lesion shape (p = 0.003, p = 0.014, respectively). According to the HP diagnosis, no statistically significant difference was found among other variables (p > 0.05) CONCLUSION: The presence of a well-defined cortical border or partial cortical border is a distinctive criterion for cysts. Additionally, the shape of the lesion was found to be a significant criterion for the separation of the two lesions. The shape of cystic lesions was circular and apical granulomas had a more curved shape. There was no relationship between the histopathological diagnosis of lesions and CBCT gray scale values.

"True" Versus "Bay" Apical Cysts: Clinical, Radiographic, Histopathologic, and Histobacteriologic Features.

INTRODUCTION: This study compared the main clinical, radiographic, and histologic features of true and bay apical cysts. METHODS: The study material comprised 95 biopsy specimens of apical periodontitis lesions obtained attached to the root tip of both untreated and root canal-treated teeth. Clinical and radiographic data were recorded. Specimens were obtained by extraction or periradicular surgery and were meticulously processed for histopathologic and histobacteriologic methods. All cases diagnosed as apical cysts (n = 23) were divided into the true and bay types, which were then compared for tooth location, patient's sex, lesion size, severity of clinical symptoms, presence of a sinus tract, previous abscess episodes, and prevalence of bacteria in the main root canal lumen and ramifications, on the outer root surface, and within the cyst cavity. RESULTS: Eleven specimens were classified as true (48%) and 12 (52%) as bay cysts. Bacteria were found in all specimens, regardless of the histopathologic diagnosis. Planktonic bacteria were observed in the main root canal in all true cysts and in 11 of 12 (92%) bay cyst cases. Biofilms were detected in the main canal in 10 cases from each diagnostic group and were frequently observed in ramifications. Extraradicular biofilms occurred in a few specimens only. Bacteria were visualized within the cavity of both true (4/11, 36%) and bay (6/12, 50%) cyst specimens. The severity of histologic inflammation was always high. There were no significant differences between true and bay cysts for all the clinical, radiographic, histopathologic, and histobacteriologic parameters assessed. CONCLUSIONS: Except for the morphologic relationship of the cyst cavity with the root canal space, true and bay cysts exhibited no other significant differences in the various parameters evaluated. The 2 cyst types were always associated with an intraradicular infection and sometimes with an extraradicular infection. Findings question the need to differentiate true and bay cysts and do not support the assumption that true cysts are self-sustainable entities not maintained by infection.

Prevalence of ciliated epithelium in apical periodontitis lesions.

INTRODUCTION: This article reports on the morphologic features and the frequency of ciliated epithelium in apical cysts and discusses its origin. METHODS: The study material consisted of 167 human apical periodontitis lesions obtained consecutively from patients presenting for treatment during a period of 12 years in a dental practice operated by one of the authors. All of the lesions were obtained still attached to the root apices of teeth with untreated (93 lesions) or treated canals (74 lesions). The former were obtained by extraction and the latter by extraction or apical surgery. Specimens were processed for histopathologic and histobacteriologic analyses. Lesions were classified, and the type of epithelium, if present, was recorded. RESULTS: Of the lesions analyzed, 49 (29%) were diagnosed as cysts. Of these, 26 (53%) were found in untreated teeth, and 23 (47%) related to root canal-treated teeth. Ciliated columnar epithelium was observed partially or completely lining the cyst wall in 4 cysts, and all of them occurred in untreated maxillary molars. Three of these lesions were categorized as pocket cysts, and the other was a true cyst. CONCLUSIONS: Ciliated columnar epithelium-lined cysts corresponded to approximately 2% of the apical periodontitis lesions and 8% of the cysts of endodontic origin in the population studied. This epithelium is highly likely to have a sinus origin in the majority of cases. However, the possibility of prosoplasia or upgraded differentiation into ciliated epithelium from the typical cystic lining squamous epithelium may also be considered.

Nonsurgical management of a periapical cyst: a case report.

Large periapical lesions, regardless of whether they are granulomas, abscesses or cysts, are primarily caused by root canal infection. Thus the treatment protocol should be elimination of etiological factors in the root canal system rather than their product, apical true cyst. A 10 year old female patient reported to the Department of Pedodontics and Preventive Dentistry, Dr R Ahmed Dental College & Hospital, Kolkata, with the chief complaint of pain and swelling in relation to upper front fractured teeth. Clinical and radiological findings were suggestive of periapical radicular cyst. Non-surgical endodontic therapy was performed using 1% sodium hypochlorite solution irrigant and Calcium hydroxide intra canal medicament. A 12 months follow-up radiographic examination revealed progressive involution of periapical radiolucency without any clinical symptoms. Periapical cysts respond favorably to non-surgical endodontic treatment and should be considered as primary treatment modality. How to cite this article: Dandotikar D, Peddi R, Lakhani B, Lata K, Mathur A, Chowdary U K. Nonsurgical Management of a Periapical Cyst: A Case Report. J Int Oral Health 2013; 5(3):79-84.

Quiste periodóntico apical de gran tamaño en el maxilar: reporte de un caso clínico / Apical periodontal cyst in the maxilla large: a case report

La lesión quística es una cavidad anormal revestida de epitelio que contiene material líquido o semisólido, la cual consta de tres estructuras fundamentales: una cavidad central (luz), un revestimiento epitelial y una pared externa. El quiste periodontico apical es la lesión quística más frecuente de la cavidad bucal, representando aproximadamente 50 a 75 % de todos los quistes verdaderos. Dicha entidad tiene su origen en la proliferación de pequeños residuos epiteliales odontogénicos (restos epiteliales de Malassez). Suele diagnosticarse al realizar exámenes radiográficos de rutina. No hay predilección por sexo y se presenta la mayor incidencia entre la 2da a 5ta década de vida, siendo el incisivo central superior el diente más afectado. Usualmente no hay dolor ni molestia asociado al quiste a menos que se infecte secundariamente. Clínicamente la patología presenta un comportamiento de crecimiento lento, pudiendo expandir las corticales óseas con deformación en el lugar de nacimiento del quiste, borrando los surcos de la cara o produciendo deformidad facial, desplazamiento dentario y dolor. Radiográficamente se observa una imagen radiolúcida que tiene forma redonda u ovoide y presenta un borde radiopaco delgado, contiguo a la lámina dura del diente. Su tratamiento se determina principalmente por el tamaño de la lesión, siendo considerada la enucleación quirúrgica y la marzupialización. A continuación se presenta un caso clínico de un paciente de sexo masculino, que presenta una lesión de grandes dimensiones, invadiendo el seno maxilar, se realizó eliminación quirúrgica y estudio histopatológico, dando como resultado quiste periodóntico apical

The cystic injury is an abnormal cavity redressed in epithelium that contains liquid or semisolid material, which consists of three fundamental structures: a central cavity (light), a coating epitelial and an external wall. The peri-apical cyst is the most frequent cystic lesion in oral cavity, representing approximately 50 to 75 % of all cysts. The above mentioned entity has it's origin in the proliferation of small odontogenic ephithelial rests (rests of Malassez). It's often diagnosed whith routine radiographic examination. There is no predilection for sex and it's frequently found between 2th and 5th decade of life, being the maxilar central incisor the most affected tooth. Usually there is neither pain nor inconvenience associated with the cyst until it becomes secondarily infected. Clinical the pathology presents a slow growth behavior, being able to expand the cortical bone with deformation in the place of birth of the cyst, erasing the facial lines or producing facial deformity, displacement of teeth and pain. Radiographically it shows an egg-shaped or round radiolucid image, and it presents a radiopaque thin halo, contiguous to the hard sheet of the tooth. The treatment is determined mainly by the size of the injury, being considered surgical enucleación and the marzupialization. In the present article, it is our aim to present a clinical case of male patient, who presents a large injury invading the maxillary sinus, surgical elimination and hystopathological study were carried out, giving as result peri-apical cyst

Apical Cyst Theory: a Missing Link.

INTRODUCTION: The mechanism of the formation of apical cyst has been elusive. Several theories have long been proposed and discussed speculating how an apical cyst is developed and formed in the jaw bone resulting from endododontic infection. Two popular theories are the nutritional deficiency theory and the abscess theory. The nutritional deficiency theory assumes that the over proliferated epithelial cells will form a ball mass such that the cells in the center of the mass will be deprived of nutrition. The abscess theory postulates that when an abscess cavity is formed in connective tissue, epithelial cells proliferate and line the preexisting cavity because of their inherent tendency to cover exposed connective tissue surfaces. Based on the nature of epithelial cells and the epithelium, nutritional theory is a fairy tale, while abscess theory at best just indicates that abscess may be one of the factors that allows the stratified epithelium to form but not to explain a mechanism that makes the cyst to form. THE HYPOTHESIS: Apical cyst formation is the result of proliferation of resting epithelial cells, due to inflammation, to a sufficient number such that they are able to form a polarized and stratified epithelial lining against dead tissues or foreign materials. These stratified epithelial lining expands along the dead tissue or foreign materials and eventually wrap around them as a spherical sac, i.e. a cyst. The space in the sac is considered the external environment separating the internal (tissue) environment - the natural function of epithelium. EVALUATION OF THE HYPOTHESIS: This theory may be tested by introducing a biodegradable device able to slowly release epithelial cell mitogens in an in vivo environment implanted with epithelial cells next to a foreign object. This will allow the cells to continuously proliferate which may form a cystic sac wrapping around the foreign object.