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1.
Traffic Inj Prev ; : 1-7, 2024 Oct 02.
Article in English | MEDLINE | ID: mdl-39356737

ABSTRACT

OBJECTIVE: This study quantifies the change in collision avoidance performance of autonomous emergency braking (AEB) systems for traffic accidents in Japan since 2015. METHOD: This study used data on Japanese traffic accidents compiled by Japan's National Police Agency. The data included only accidents involving loss of or injury to human life; accidents involving only property damage were excluded. We restricted our analysis to collisions between two 4-wheel vehicles and considered only collisions for which we could determine whether the primary party's car was equipped with an AEB system. Both Poisson and negative binomial mixed-effects regression analyses were conducted using the data for 2021 and 2022 to measure the collision avoidance performance of first registered cars in 2015 to 2020 equipped with AEB systems compared with cars without AEB systems first registered in 2015. Collision avoidance performance was measured for 2 types of intervehicle collisions: rear-end collisions and right-turn collisions. Collision avoidance performance for rear-end collisions was also measured for each of the 3 car types-Standard, small, and light cars. RESULTS: The collision reduction rate for rear-end collisions increases with the year of first registration and for cars equipped with AEB systems first registered in 2020 compared with non-AEB-equipped cars first registered in 2015 is 69.2% (95% confidence interval [CI] 67.0%-71.1%), indicating that the performance of AEB systems has dramatically improved in terms of preventing rear-end collisions. For right-turn collisions, the rate increased to 20.4% (95% CI 5.9%-32.6%) for cars equipped with AEB systems first registered in 2019. However, no clear trend is observed. CONCLUSIONS: This study evaluated a time series of the collision reduction performance of AEB systems using an original methodology. Japan's New Car Assessment Program (JNCAP) has included AEB's effectiveness in reducing damage from traffic collisions as an evaluation item since FY2014. The results could demonstrate the effectiveness of JNCAP.

2.
Talanta ; 282: 126951, 2024 Oct 01.
Article in English | MEDLINE | ID: mdl-39357400

ABSTRACT

Horseradish peroxidase (HRP) is a versatile biosensing label and signal reporter owing to its broad-spectrum catalytic ability. In present work, we characterized HRP's catalytic performance with various substrates using electrochemical collision technique and analyzed the associated electron transfer processes. Different electrolyte solutions greatly affected enzyme dispersibility and zeta potential, thereby impacting HRP collision dynamics in single H2O2 substrate system. The maximum turnover number (kcat) for single HRP molecules was calculated to be 3.611 ± 0.149 × 103 s-1 in 0.85 % NaCl and 2.967 ± 0.286 × 103 s-1 in 0.1 M PBS solution, reflecting differences in cluster size induced by the electrolyte conditions. More severe agglomeration of HRP molecules was observed in double-substrate systems, where the hydrophilic mediator (K4Fe(CN)6) and lipophilic mediator (ABTS) served as electron donors and signal reporters. The calculated kcat value of single HRP molecules in ABTS-H2O2 was 7.6 times higher than that in K4Fe(CN)6-H2O2. This difference is attributed to mediators' solubility, lipophilicity, and HRP's affinity for different substrates, with HRP demonstrated stronger affinity for ABTS-H2O2 substrates, which realized more efficient electron transfer and compensated for the low diffusion coefficient of ABTS. This work provides a comprehensive analysis of the effects of electrolytes and substrates on HRP collision and catalytic behavior, offering valuable insights for the advanced design of HRP-based biosensors and diagnostic platforms.

3.
Brain Inj ; : 1-9, 2024 Oct 02.
Article in English | MEDLINE | ID: mdl-39359046

ABSTRACT

OBJECTIVES: Evaluate professional rugby players' self-reported perceived understanding of the head injury assessment (HIA) and return to play (RTP) processes and determine factors related to understanding and trust pertaining to these processes. METHODS: An electronic survey measured concepts of interest. A thematic analysis of player understanding was performed, and player statements were coded. RESULTS: 207 U.S. Major League Rugby (MLR) players participated (26.7 ± 3.4 years). HIA and RTP protocol understanding was not correlated with concussion history (p = 0.41). International rugby experience and trust regarding MLR support of the following protocols and opposing team medical staff practices varied in their relationship to HIA understanding. Trust that all MLR teams follow the same protocols was positively correlated with all HIA questions (ps < 0.03). No HIA questions were correlated with trust in their own team's medical staff. All trust questions were significantly correlated with RTP process understanding. Qualitative analysis identified four HIA- and RTP-related themes: education needs, staffing needs, HIA criticisms, and importance of player safety. CONCLUSION: International playing experience and greater trust in the MLR and league stakeholders were associated with greater player understanding of the HIA and RTP protocols. These results provide insight into the importance of educating players on league-specific concussion protocols.

4.
J Mass Spectrom ; 59(10): e5096, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39352836

ABSTRACT

The unimolecular reactions of protonated myrcene and linalool were investigated by collision-induced dissociation and density functional theory calculations. Experiments on a triple quadrupole mass spectrometer showed that protonated myrcene undergoes two major unimolecular reactions losing propene and isobutene, and two minor reactions of ethene and propane loss. In each case, the product ion consists of a substituted five-member ring. Protonation of myrcene was found to form four distinct protomers, three of which can be significantly populated in the ion source. The observed fragmentation reactions were calculated and found to depend on the starting protomer. Each pathway consisted of several hydrogen-migration and ring-forming/opening steps on the way to the observed products. Likewise, protonation of linalool also produces three distinct protomers, with the global minimum being formed by protonation of a central double bond. The major reaction is water loss to form protonated myrcene, but two minor channels were also observed resulting in loss of acetone and isobutene. The calculated minimum energy reaction pathways were found to be consistent with the relative abundances of the ions in the experimental breakdown diagrams.

5.
Anal Bioanal Chem ; 2024 Oct 05.
Article in English | MEDLINE | ID: mdl-39367908

ABSTRACT

Comprehensive in-depth structural characterization of free mono-unsaturated and polyunsaturated fatty acids often requires the determination of carbon-carbon double bond positions due to their impact on physiological properties and relevance in biological samples or during impurity profiling of pharmaceuticals. In this research, we report on the evaluation of disulfides as suitable derivatization reagents for the determination of carbon-carbon double bond positions of unsaturated free fatty acids by UHPLC-ESI-QTOF-MS/MS analysis and SWATH (sequential windowed acquisition of all theoretical mass spectra) acquisition. Iodine-catalyzed derivatization of C = C double bonds with dimethyl disulfide (DMDS) enabled detection of characteristic carboxy-terminal MS2 fragments for various fatty acids in ESI negative mode. The determination of double bond positions of fatty acids with up to three double bonds, the transfer of the method to plasma samples, and its limitations have been shown. To achieve charge-switching for positive ion mode MS-detection, derivatization with 2,2'-dipyridyldisulfide (DPDS) was investigated. It enabled detection of both corresponding characteristic omega-end- and carboxy-end-fragments for fatty acids with up to two double bonds in positive ion mode. It provides a straightforward strategy for designing MRM transitions for targeted LC-MS/MS assays. Both derivatization techniques represent a simple and inexpensive way for the determination of double bond positions in fatty acids with low number of double bonds. No adaptation of MS hardware is required and the specific isotopic pattern of resulting sulfur-containing products provides additional structural confirmation. This reaction scheme opens up the avenue of structural tuning of disulfide reagents beyond DMDS and DPDS using reagents like cystine and analogs to achieve enhanced performance and sensitivity.

6.
Front Surg ; 11: 1416801, 2024.
Article in English | MEDLINE | ID: mdl-39364374

ABSTRACT

Background: An adrenal collision tumor (ACT) denotes the presence of distinct tumors with diverse behavioral, genetic, and histological features independently co-existing within the adrenal tissue without intermingling, and occurrences of such cases are infrequent. The concurrent occurrence of adrenal schwannoma and adrenal ganglioneuroma is exceedingly rare, and the diagnosis of these ACTs has been notably challenging due to their atypical clinical manifestations and imaging characteristics. Case summary: A 37-year-old man presented to the hospital 3 weeks after a computed tomography (CT) examination that revealed a left adrenal mass. Physical examination findings were unremarkable. Both CT and magnetic resonance imaging scans indicated the presence of a left adrenal mass. Plasma cortisol, adrenocorticotropic hormone, and renin-angiotensin-aldosterone system tests yielded normal results. Preoperative imaging confirmed the diagnosis of left adrenal pheochromocytoma. After thorough surgical preparation, a laparoscopic partial left adrenalectomy was performed. Subsequent postoperative pathological analysis identified adrenal schwannoma in conjunction with adrenal ganglioneuroma. The patient recovered well and was discharged on postoperative day 4. A routine urology clinic visit was included in his postoperative care plan. During follow-up assessments, CT scans of the left adrenal gland revealed no abnormalities. Conclusion: Adrenal schwannoma combined with ganglioneuroma represents an exceptionally rare collision tumor characterized by the absence of typical clinical or imaging features, leading to potential misdiagnosis. Adrenal incidentalomas present as multifaceted conditions, and this case serves to heighten awareness of their intricate nature. Due to the challenges in preoperative differentiation of various adrenal mass types, postoperative pathological analysis is imperative for guiding the subsequent treatment course for the patient.

8.
AME Case Rep ; 8: 109, 2024.
Article in English | MEDLINE | ID: mdl-39380877

ABSTRACT

Background: Collision tumors of the gastrointestinal (GI) tract are thought to be uncommon, with those of the colon being rare with very few cases reported in current literature. There are three proposed theories regarding the etiology of collision tumors currently, including the "double primaries", the "biclonal malignant transformation", and the "tumor-to-tumor carcinogenesis" theories. Prognosis of collision tumors remains unclear. To our knowledge, this is the fifth case of a collision carcinoma involving the cecum and ileocecal valve and the first report of a collision carcinoma including both mucinous adenocarcinoma and neuroendocrine tumor of the cecum and the ileocecal valve. The aim of this paper is to explore the history of collision tumors and associated nomenclature, defined diagnostic criteria, and proposed theories for etiology in addition to patient presentation, approach to diagnosis, treatment options, and prognosis. Case Description: We present the case of an 83-year-old female who presented to the emergency room with a 4-month history of cramping abdominal pain associated with nausea, emesis, and decreased appetite with associated weight loss. Diagnostic imaging demonstrated a bowel obstruction secondary to a mass in the cecum and she underwent an exploratory laparotomy with right hemicolectomy. She was found to have a collision carcinoma of the cecum and ileocecal valve containing both mucinous adenocarcinoma and neuroendocrine tumor. Diagnosis was confirmed post-operatively with pathologic examination and immunohistochemical testing. Conclusions: Diagnosing collision tumors upon patient presentation is exceedingly difficult as the symptoms are often identical to other neoplasms of the GI tract and vary based on location of the tumor. It is thought that the true prevalence of collision tumors is underestimated due to history of changing nomenclature, unclear diagnostic criteria, unreported cases, and unrecognized cases. Furthermore, new advances in immunohistochemical evaluation have allowed for better characterization of these neoplasms. With clarification regarding nomenclature, diagnostic criteria and expanding awareness, it is our hope that this leads to an increase in reported cases, allowing for an expanded discussion and resulting growth of literature and further studies. Further knowledge regarding the pathogenesis, treatment, and prognosis is needed.

9.
J Bacteriol ; : e0013924, 2024 Oct 09.
Article in English | MEDLINE | ID: mdl-39382272

ABSTRACT

Although the development of disinfection technologies with novel mechanisms has stagnated, we demonstrate the bactericidal effects and mechanisms of high-speed nanodroplet generation technology. The first development of this technology in 2017 gushes out a water droplet of 10 nm in size at 50 m/s; however, the target surface does not become completely wet. Nanodroplets were exposed to biofilm models of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Serratia marcescens. This phenomenon was verified when the nanodroplets collide with the surface of the bacteria at an impact pressure of ~75 MPa. S. aureus was exposed to nanodroplets for 30 seconds at 75 MPa, which exploded the bacterial body and completely sterilized. Eighteen MPa damaged the bacterial surface, causing peptidoglycan leakage. S. aureus was repaired and survives in this state. In contrast, in Gram-negative bacteria, nanodroplets with 18 MPa penetrated some biofilm-forming bacteria but did not hit all of them, and the viable count was not significantly reduced. Although all three bacterial species were completely sterilized at 75 MPa, the disinfectant effect was affected by the biomass of the biofilm formed. In summary, our findings prove that nanodroplets at 18 MPa on the bacterial surface were ineffective in killing bacteria, whereas at 75 MPa, all four bacterial species were completely sterilized. The disinfection mechanism involved a high-velocity collision of nanodroplets with the bacteria, physically destroying them. Our results showed that disinfection using this technology could be an innovative method that is completely different from existing disinfection techniques. IMPORTANCE: Although existing disinfection techniques demonstrate bactericidal effects through chemical reactions, concerns regarding human toxicity and environmental contamination have been raised. To the best of our knowledge, this study is the first in the world to reveal that the use of this technology, with nanodroplets of less than 100 nm, can destroy and sterilize bacterial cells by colliding with biofilm-forming bacteria at 75 MPa. Furthermore, because this technology uses only water, it can solve the problems of human toxicity and environmental contamination caused by existing disinfection techniques. Because of its minimal water usage, it can be employed for sanitation worldwide without being limited to specific regions. Our report proposes an unprecedented physical disinfection approach that utilizes a high-speed nanodroplet generation technology.

10.
JFMS Open Rep ; 10(2): 20551169241269292, 2024.
Article in English | MEDLINE | ID: mdl-39219664

ABSTRACT

Case summary: A 2-year-old spayed female domestic shorthair cat presented with tetraparesis after being involved in a road traffic accident. Survey spine radiographs revealed a C2-C3 cervical subluxation, which was confirmed by a CT scan. Surgical stabilisation was performed using screws and polymethyl methacrylate (PMMA) via a ventral approach. A postoperative CT scan demonstrated correct implant positioning and good reduction of the subluxation. After surgery, the cat rapidly recovered to a neurologically normal status. Relevance and novel information: Trauma-induced cervical subluxation is an uncommon occurrence in cats but should be considered in the differential diagnosis. This report describes the surgical management of a C2-C3 cervical subluxation in a cat using screws and PMMA. This is the first case report of a surgically treated subaxial cervical subluxation in a cat.

11.
Spine Deform ; 2024 Sep 04.
Article in English | MEDLINE | ID: mdl-39230663

ABSTRACT

PURPOSE: Neurological deficits developing years after pedicle screw misplacement is a rare phenomenon. Here, we report level IV evidence of a previously asymptomatic medial thoracic pedicle screw resulting in paraparesis after a motor vehicle accident. METHODS: A 21-year-old male presented with acute onset of paraparesis following a motor vehicle collision. Six years prior this incident, the patient underwent a thoracolumbar fusion T4-L4 for AIS performed by an outside orthopedic surgeon. CT scan and CT myelogram illustrated decreased spinal canal diameter and cord compression from a medial T8 pedicle screw. RESULTS: Surgical removal of the misplaced pedicle screw resulted in a gradual complete recovery sustained over a period of 2 years. This case is compared to those reported in the literature review between 1981 and 2019 concerning delayed neurological deterioration related to misplaced pedicle screw. CONCLUSION: This case reports a delayed neurological deficit implicating a misplaced pedicle screw. This phenomenon remains rare since 5 cases were reported in the literature over the last 4 decades. It calls into focus the need for confirmation of safe instrumentation during the intraoperative period. It also illustrates the potential difficult decision-making in regard to asymptomatic misplaced instrumentation. LEVEL OF EVIDENCE: IV.

12.
J Youth Adolesc ; 2024 Sep 13.
Article in English | MEDLINE | ID: mdl-39269587

ABSTRACT

Sexual minority youth experience disproportionate rates of mental health symptomatology relative to their heterosexual peers. Less is known about why these disparities have persisted despite growing public awareness of sexual diversity. The developmental collision hypothesis states that increased cultural visibility of sexual diversity has accelerated the developmental timing of sexual minority identity formation processes such that they collide with early adolescence, a uniquely sensitive period for experiencing identity-based stigma and associated mental health vulnerability. To test this hypothesis, levels and relations between ages of sexual minority identity development milestones, frequency of LGBT-related victimization, and depressive symptoms were examined across three age-matched but cohort-distinct samples of sexual minority adolescents. Data come from three secondary datasets of sexual minority youth who were adolescents in the 1990s, 2000s, and 2010s, respectively: the Challenges and Coping Study, the Victimization and Mental Health among High Risk Youths Study, and the Risk and Protective Factors for Suicide among Sexual Minority Youth Study (n = 1312; Mage = 17.34, SD = 1.30; 52% female). Adolescents from more recent cohorts reported earlier mean ages of several milestones but similar frequencies of LGBT-related victimization relative to those from less recent cohorts. Path analysis models showed that earlier milestones were associated indirectly with more depressive symptoms through LGBT-related victimization. Notably, earlier ages of self-identification and disclosure of a sexual minority identity were also directly related to less depressive symptoms. Few generational differences in relations between constructs emerged. Findings garner initial support for the developmental collision hypothesis and suggest that LGBT-related victimization, rather than earlier milestones themselves, increases mental health vulnerability.

13.
Risk Anal ; 2024 Sep 14.
Article in English | MEDLINE | ID: mdl-39276027

ABSTRACT

Advantages of commercial UAS-based services come with the disadvantage of posing third party risk (TPR) to overflown population on the ground. Especially challenging is that the imposed level of ground TPR tends to increase linearly with the density of potential customers of UAS services. This challenge asks for the development of complementary directions in reducing ground TPR. The first direction is to reduce the rate of a UAS crash to the ground. The second direction is to reduce overflying in more densely populated areas by developing risk-aware UAS path planning strategies. The third direction is to develop UAS designs that reduce the product A impact · P { F | impact } ${{A}_{{\mathrm{impact}}}} \cdot \mathbb{P}\{ F| {{\mathrm{impact}}\} } $ in case of a crashing UAS, where A impact ${{A}_{{\mathrm{impact}}}}$ is the size of the crash impact area on the ground, and P { F | impact } $\mathbb{P}\{ F| {{\mathrm{impact}}\} } $ is the probability of fatality for a person in the crash impact area. Because small UAS accident and incident data are scarce, each of these three developments is in need of predictive models regarding their contribution to ground TPR. Such models have been well developed for UAS crash event rate and risk-aware UAS path planning. The objective of this article is to develop an improved model and assessment method for the product A impact · P { F | impact } . ${{A}_{{\mathrm{impact}}}} \cdot \mathbb{P}\{ F| {{\mathrm{impact}}\} } .$ In literature, the model development and assessment of the latter two terms is accomplished along separate routes. The objective of this article is to develop an integrated approach. The first step is the development of an integrated model for the product A impact · P { F | impact } ${{A}_{{\mathrm{impact}}}} \cdot \mathbb{P}\{ F| {{\mathrm{impact}}\} } $ . The second step is to show that this integrated model can be assessed by conducting dynamical simulations of Finite Element (FE) or Multi-Body System (MBS) models of collision between a UAS and a human body. Application of this novel method is illustrated and compared to existing methods for a DJI Phantom III UAS crashing to the ground.

14.
Clin Sports Med ; 43(4): 617-633, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39232570

ABSTRACT

Historically considered the gold standard technique for glenohumeral instability, the open Bankart repair is being performed at decreased rates because of the current trends favoring arthroscopic Bankart repair and the lack of consistent training of the open technique. However, open Bankart repairs may be more appropriate for certain high-risk populations (ie, high-level collision athletes) because of their reduced recurrent instability rates. Further investigations are needed to identify the indications for arthroscopic versus open Bankart repair and compare their outcomes in high-level athletes. This review highlights the indications, surgical technique, and clinical outcomes following open Bankart repairs in athletes.


Subject(s)
Arthroscopy , Athletic Injuries , Joint Instability , Humans , Joint Instability/surgery , Athletic Injuries/surgery , Arthroscopy/methods , Shoulder Dislocation/surgery , Treatment Outcome , Shoulder Joint/surgery
15.
Accid Anal Prev ; 208: 107764, 2024 Sep 09.
Article in English | MEDLINE | ID: mdl-39255561

ABSTRACT

Driver assistance systems play an important role in enhancing vehicle active safety. However, most of the existing driver assistance systems overlook the impact of driver characteristics on control performance, making it difficult to optimize the intervention strength of the controller for different drivers to achieve optimal performance. This paper proposed a novel vehicle active collision avoidance control strategy considering driver characteristics. By adjusting the time domain parameters of the model predictive control (MPC), collision avoidance assistance can be more effectively tailored to different types of drivers. Firstly, the collected lane-changing and collision avoidance data of 10 drivers with varying levels of experience were analyzed and preprocessed. Based on this analysis, a comprehensive index of collision avoidance characteristics was established that integrated trajectory tracking ability and driver burden, enabling the derivation of the collision avoidance characteristic curve representing the driver's preference and habit was obtained. Secondly, a sixth-order polynomial trajectory planning method considering driver characteristics was proposed. This method was optimized under vehicle stability and driver matching constraints to generate personalized collision avoidance trajectories for different drivers. The proposed comprehensive index and personalized collision avoidance trajectory were incorporated into the active collision avoidance control system, and a personalized time-variable domain MPC controller was designed. Test results based on a driver-in-the-loop bench demonstrate that the proposed personalized MPC could better match diverse driving characteristics, enhance the driver's trajectory tracking ability in the process of collision avoidance, reduce the driving workload, thereby improving overall driving safety and comfort.

16.
Accid Anal Prev ; 208: 107726, 2024 Sep 11.
Article in English | MEDLINE | ID: mdl-39265379

ABSTRACT

Reconstructing individual cases from real-world collision data is used as a tool to better understand injury biomechanics and determine injury thresholds. However, real-world data tends to have inherent uncertainty within parameters, such as ranges of impact speed, pre-impact pedestrian stance or pedestrian anthropometric characteristics. The implications of this input parameter uncertainty on the conclusions made from case reconstruction about injury biomechanics and risk is not well investigated, with a 'best-fit' approach more frequently adopted, leaving uncertainty unexplored. This study explores the implications of uncertain parameters in real-world data on the biomechanical kinematic metrics related to head injury risk in reconstructed real-world pedestrian-car collisions. We selected six pedestrian-car cases involving seven pedestrians from the highly detailed GB Road Accident In-Depth Studies (RAIDS) database. The collisions were reconstructed from the images, damage measurements and dynamics available in RAIDS. For each case, we varied input parameters within uncertain ranges and report the range of head kinematic metrics from each case. This includes variations of reconstructed collision scenarios that fits within the constraints of the available evidence. We used a combination of multibody and finite element modelling in Madymo to test whether the effect of input data uncertainty is the same on the initial head-vehicle and latter head-ground impact phase. Finally, we assessed whether the predicted range of head kinematics correctly predicted the injuries sustained by the pedestrian. Varying the inputs resulted in a range of output head kinematic parameters. Real-world evidence such as CCTV footage enabled predicted simulated values to be further constrained, by ruling out unrealistic scenarios which do not fit the available evidence. We found that input data uncertainty had different implications for the initial head-vehicle and latter head-ground impact phase. There was a narrower distribution of kinematics associated with the head-vehicle impact (initial 400 ms of the collision) than in the latter head-ground impact. The mean head-vehicle kinematics were able to correctly predict the presence or absence of both subdural haematoma (using peak rotational acceleration) and skull vault fracture (using peak contact force) in all pedestrians presented. This study helps increase our understanding of the effects of uncertain parameters on head kinematics in pedestrian-car collision reconstructions. Extending this work to a broad range of pedestrian-vehicle collision reconstructions spanning broad population demographics will improve our understanding of injury mechanisms and risk, leading to more robust design of injury prevention measures.

17.
Proteomics ; : e2400223, 2024 Sep 05.
Article in English | MEDLINE | ID: mdl-39233542

ABSTRACT

Adeno-associated viruses (AAVs) are common vectors for emerging gene therapies due to their lack of pathogenicity in humans. Here, we present our investigation of the viral proteins (i.e., VP1, VP2, and VP3) of the capsid of AAVs via top-down mass spectrometry (MS). These proteins, ranging from 59 to 81 kDa, were chromatographically separated using hydrophilic interaction liquid chromatography and characterized in the gas-phase by high-resolution Orbitrap Fourier transform MS. Complementary ion dissociation methods were utilized to improve the overall sequence coverage. By reducing the overlap of product ion signals via proton transfer charge reduction on the Orbitrap Ascend BioPharma Tribrid mass spectrometer, the sequence coverage of each VP was significantly increased, reaching up to ∼40% in the case of VP3. These results showcase the improvements in the sequencing of proteins >30 kDa that can be achieved by manipulating product ions via gas-phase reactions to obtain easy-to-interpret fragmentation mass spectra.

18.
Surg Neurol Int ; 15: 282, 2024.
Article in English | MEDLINE | ID: mdl-39246779

ABSTRACT

Background: Collision tumors involving the co-occurrence of two morphologically and genomically distinct neoplasms in the same anatomical site are exceptionally rare in the central nervous system (CNS). Case Description: We report a unique case of a CNS collision tumor comprising chronic lymphocytic leukemia and myxopapillary ependymoma in a 77-year-old male with acute neurological decline. Presumed to represent leukemic infiltration, urgent laminectomy was pursued for tissue diagnosis and spinal cord decompression, revealing the unexpected ependymal component. Conclusion: This case highlights the diagnostic and therapeutic challenges inherent to managing collision CNS tumors, particularly when one neoplasm is hematological.

19.
Front Psychol ; 15: 1414702, 2024.
Article in English | MEDLINE | ID: mdl-39323584

ABSTRACT

Estimating the time until impending collision (time-to-collision, TTC) of approaching or looming individuals and maintaining a comfortable distance from others (interpersonal distance, IPD) are commonly required in daily life and contribute to survival and social goals. Despite accumulating evidence that facial expressions and gaze direction interactively influence face processing, it remains unclear how these facial features affect the spatiotemporal processing of looming faces. We examined whether facial expressions (fearful vs. neutral) and gaze direction (direct vs. averted) interact on the judgments of TTC and IPD for looming faces, based on the shared signal hypothesis that fear signals the existence of threats in the environment when coupled with averted gaze. Experiment 1 demonstrated that TTC estimates were reduced for fearful faces compared to neutral ones only when the concomitant gaze was averted. In Experiment 2, the emotion-gaze interaction was not observed in the IPD regulation, which is arguably sensitive to affective responses to faces. The results suggest that fearful-averted faces modulate the cognitive extrapolation process of looming motion by communicating environmental threats rather than by altering subjective fear or perceived emotional intensity of faces. The TTC-specific effect may reflect an enhanced defensive response to unseen threats implied by looming fearful-averted faces. Our findings provide insight into how the visual system processes facial features to ensure bodily safety and comfortable interpersonal communication in dynamic environments.

20.
Front Plant Sci ; 15: 1393541, 2024.
Article in English | MEDLINE | ID: mdl-39319006

ABSTRACT

Currently, precise spraying of sweet potatoes is mainly accomplished through semi-mechanized or single spraying robots, which results in low operating efficiency. Moreover, it is time-consuming and labor-intensive, and the pests and diseases cannot be eliminated in time. Based on multi robot navigation technology, multiple robots can work simultaneously, improving work efficiency. One of the main challenges faced by multi robot navigation technology is to develop a safe and robust collision avoidance strategy, so that each robot can safely and efficiently navigate from its starting position to the expected target. In this article, we propose a low-cost multi-robot collision avoidance method to solve the problem that multiple robots are prone to collision when working in field at the same time. This method has achieved good results in simulation. In particular, our collision avoidance method predicts the possibility of collision based on the robot's position and environmental information, and changes the robot's path in advance, instead of waiting for the robot to make a collision avoidance decision when it is closer. Finally, we demonstrate that a multi-robot collision avoidance approach provides an excellent solution for safe and effective autonomous navigation of a single robot working in complex sweet potato fields. Our collision avoidance method allows the robot to move forward effectively in the field without getting stuck. More importantly, this method does not require expensive hardware and computing power, nor does it require tedious parameter tuning.

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