ABSTRACT
Muchas técnicas se han propuesto con el fin de optimizar la ejecución y desarrollo de los procedimientos en cirugía. Algunas sehan mantenido a lo largo del tiempo y otras han dejado de utilizarse por muy variados motivos. La sinemaprapía fue un procedimiento que, aunque si bien tuvo antecedentes de empleo por algunos autores de forma ocasional, fue el Catedrático de AnatomíaQuirúrgica, Operaciones, Apósitos y Vendajes Vicente Sagarra Lascurain el que la promociono a finales del siglo XIX y principiosdel XX. Quiso destacar en ella su sencillez de uso, eficacia en la diéresis y sobre todo la menor hemorragia que se producía en laherida quirúrgica en su aplicación, que la hacía muy adecuada su empleo en tejidos y órganos muy vascularizados, como eran lasamputaciones de pene y lengua. La técnica se empleo de una forma no muy extendida y con el paso del tiempo quedó olvidada. Eltrabajo trata de recordar desde el punto de vista histórico esta técnica, su empleo, las indicaciones de uso y referencia a sus resultados, profusamente publicados por su promotor. (AU)
Many techniques have been proposed in order to optimize the performance and development of surgical procedures. Some have beenmaintained over time and others have been discontinued for a variety of reasons. Sinemaprasía was a procedure, which althoughit had a history of employment by some authors occasionally, it was the Professor of Surgical Anatomy, Operations, Dressings andBandages, Vicente Sagarra Lascurain who promoted it at the end of the 19th and early 20th centuries. He wanted to highlight in itits simplicity of use, effectiveness in the umlaut and above all the less bleeding that occurred in the surgical wound in its application,which made it very suitable for use in highly vascular tissues and organs, such as penile amputations. and tongue. The techniquewas used in a not very widespread way and with the passage of time it was forgotten. The work tries to remember from the historicalpoint of view this technique, its use, the indications for use and reference to its results, widely published by its promoter. (AU)
Subject(s)
Humans , History, 19th Century , History, 20th Century , General Surgery/history , General Surgery/methods , Suture Techniques/historyABSTRACT
OBJECTIVE: Urinary radiotracer excretion of 68Ga-Labelled prostate-specific membrane antigen (PSMA) ligands may complicate the assessment of the prostate region and differentiation of lymph nodes from ureteral activity. The aim of this study was to assess the value of delayed imaging after forced diuresis. MATERIALS AND METHODS: Sixty-six patients underwent 68Ga-PSMA I&T PET/CT for evaluation of prostate cancer at 60 min post-injection. In subgroups of patients, this was amended by delayed imaging after 180 min post-injection, preceded by furosemide and oral hydration early, at the time of tracer injection, or delayed, at 100 min post-injection. Urinary tracer activity within the bladder and focal ureteral activity was analyzed. RESULTS: After forced diuresis, linear and focal visualization of ureters was significantly reduced. After delayed furosemide, mean and peak bladder activity decreased (p < 0.001), and image quality of the prostate region improved on delayed images (p < 0.001). Early furosemide co-injection with tracer resulted in increased mean and peak bladder activity (p < 0.001) and in deteriorated image quality of the prostate region on delayed images (p = 0.008). CONCLUSION: Ga-PSMA I&T PET/CT delayed imaging after forced diuresis can improve the assessment of prostate region and pelvic lymph nodes by removing excreted tracer from the lower urinary tract. KEY POINTS: ⢠Forced diuresis can improve image quality in 68 Ga-PSMA I&T. ⢠After forced diuresis, linear and focal visualization of ureters was reduced. ⢠Timing of diuresis relative to 68 Ga-PSMA I&T injection is important. ⢠Early furosemide co-injection with tracer resulted in deteriorated image quality on delayed images. ⢠After delayed furosemide, image quality improved on delayed images.
Subject(s)
Antigens, Surface , Glutamate Carboxypeptidase II , Positron Emission Tomography Computed Tomography/methods , Prostatic Neoplasms/diagnostic imaging , Radiopharmaceuticals , Aged , Aged, 80 and over , Diuresis/physiology , Female , Humans , Lymph Nodes/pathology , Lymphatic Metastasis , Male , Middle Aged , Pelvis/pathology , Prostatic Neoplasms/pathology , Prostatic Neoplasms/physiopathologyABSTRACT
This article was aimed to study the effect ofXiao-Qing-LongDecoction (XQLD) on plasma AngⅡ, ALD, Na+-k+-ATPase content, and plasma AT1 and AT2 mRNA expressions in Cor pulmonale rats, in order to further explore the mechanism of ventilating lung qi for diuresis. A total of 60 Wistar rats were randomly divided into the normal group, model group and XQLD, with 20 rats in each group. The enzyme-linked immunosorbent assay (ELISA) method was used to determine the AngⅡ, ALD and Na+-k+-ATPase content. The fluorescence quantitative PCR was used to detect the AT1 and AT2 mRNA expression. The results showed that compared with the normal group, the AngⅡ, ALD and Na+-k+-ATPase contents in the model group were significantly increased (P< 0.05, orP< 0.01). Compared with the model group, the AngⅡ, ALD and Na+-k+-ATPase contents in the XQLD group were obviously decreased (P< 0.05). Compared with the normal group, AT1 mRNA expression was increased; and AT2 mRNA expression was decreased in the model group (P<0.05, orP< 0.01). Compared with the model group, AT1 mRNA expression was decreased; and AT2 mRNA expression was increased in the XQLD group (P < 0.01). It was concluded that XQLD can effectively regulate the AT1 and AT2 mRNA expressions, influence ALD content to ventilate lungqi for dieresis.
ABSTRACT
Objective] To sum up director doctor Sheng Yuanliang ’s experience in treating severe hepatitis. [Method] Through analyzing the treating rules,causa morbi and mechanism of severe hepatitis,it sums up the key points of data of severe hepatitis,with 1 case for detailed explanation. [Result] The reason of the disease is mainly“damp,heat and toxin evils”,with corresponding therapies of removing heat to promote dieresis ,removing toxin and stasis. [Conclusion] The famous TCM doctor Shen Yuangliang’s applying clearing heat to promote dieresis,removing stasis and toxin to treat severe hepatitis,gets good clinical effect,having enlightenment meaning to clinical practice,with promotion value.
ABSTRACT
This study was aimed to investigate the anti-inflammatory, diuretic effect and acute toxicity of Herb of Lanceolate Sedge. The mice were randomly divided into 5 groups, which were the physiological saline group, aspirin group (0.05 g·kg-1), high dose (HD), middle dose (MD) and low dose (LD) of water extract of Herb of Lanceolate Sedge (10, 5, 2.5 g crude drug per kg) group. Intragastric administration of medication was given to mice once a day for 3 days. Auricular swelling induced by dimethyl benzene was used in the model establishment to calculate the swollen ear degree and the swollen inhibiting rate. And rats were randomly divided into 5 groups, which were the physiological saline group, aspirin group (0.05 g·kg-1), high dose (HD), middle dose (MD) and low dose (LD) of wa-ter extract of Herb of Lanceolate Sedge (10, 5, 2.5 g crude drug per kg) group. Intragastric administration of medi-cation was given to rats once a day for 5 days. Carrageenan induced paw edema was used in the model establishment to calculate the paw swollen rate. And rats were randomly divided into 5 groups, which were the physiological saline group, Furosemide tablets group (0.01 g·kg-1), high dose (HD), middle dose (MD) and low dose (LD) of water extract of Herb of Lanceolate Sedge (10, 5, 2.5 g crude drug per kg) group. Intragastric administration of medication was giv-en to rats once a day for 5 days. Water-loaded was used in the model establishment to calculate the 5-hour urine amount. The maximum tolerance dose (MTD) was used in the determination of the acute toxicity. The results showed that the three groups of HD, MD and LD of water extract of Herb of Lanceolate Sedge had obvious inhibiting effects on the swollen ear degree and the swollen inhibiting rate among mice, and the paw swollen rate of rats. It had signif-icant increasing effect on the 5-hour urine amount. The MTD of intragastric administration of water extract of Herb of Lanceolate Sedge was 640 g crude drug per kg for mice. It was concluded that Herb of Lanceolate Sedge dis-played obvious effects on anti-inflammatory and dieresis with low acute toxicity.
