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1.
Psychother Res ; : 1-14, 2024 Jul 08.
Article in English | MEDLINE | ID: mdl-38976630

ABSTRACT

OBJECTIVE: The study aimed to test the psychometric properties of the Czech translation of the Questionnaire of Personal Changes (Q-PC), a measure designed for retrospective (direct) measurement of change in psychotherapy. METHODS: A sample of group psychotherapy clients (N = 222) and a nonclinical sample (N = 167) sample were used. Clients in the clinical sample were administered the Q-PC in addition to several pre-post outcome measures. Confirmatory factor analysis, correlational analysis, and structural equation modeling were used to test the Q-PC's factor structure, longitudinal measurement invariance, reliability, convergent validity, sensitivity to change, and other psychometric properties. RESULTS: The Q-PC demonstrated a unidimensional structure that was strictly invariant between two follow-up measurement waves. The measure also demonstrated excellent reliability and sensitivity to change and good convergent validity. Furthermore, it demonstrated a similar relationship to baseline severity as the pre-post outcome measures. CONCLUSIONS: The retrospective measurement of change is a promising approach that has the potential to complement the traditional pre-post measurement of change.

2.
Lab Med ; 55(2): 140-144, 2024 Mar 07.
Article in English | MEDLINE | ID: mdl-37253142

ABSTRACT

OBJECTIVE: The Friedewald equation is the commonly used method of low-density lipoprotein cholesterol (LDL-C) calculation, requiring reflex to direct LDL-C measurement when triglycerides (TG) ≥ 400 mg/dL. Recently formulated Sampson and extended Martin/Hopkins methods have been validated with TG up to 800 mg/dL and thus have the potential to replace direct LDL-C measurement. Given the growing prevalence of childhood dyslipidemia, the objective of this study was to compare Sampson and extended Martin/Hopkins methods of LDL-C calculation with the direct measurement in a pediatric cohort with 400 ≤ TG ≤ 799 mg/dL. METHODS: This study retrieved standard lipid panels and corresponding direct LDL-C measurements of 131 patients with 400 ≤ TG ≤ 799 mg/dL from a pediatric population. Following the application of Sampson and extended Martin/Hopkins calculations, calculated values were compared with direct LDL-C measurements using ordinary least squares linear regression analysis and bias plotting. RESULTS: Both Sampson and extended Martin/Hopkins LDL-C calculations exhibited a strong correlation with the direct measurements (Pearson r = 0.89) in patients with 400 ≤ TG ≤ 800 mg/dL. Average percentages of bias of 45% and 21% were found between the direct LDL-C measurements and Sampson or extended Martin/Hopkins calculations, respectively. CONCLUSION: Both Sampson and extended Martin/Hopkins calculations are applicable as clinical alternatives of direct LDL-C measurement in pediatric patients given 400 ≤ TG ≤ 799 mg/dL.


Subject(s)
Hypertriglyceridemia , Humans , Child , Cholesterol, LDL , Hypertriglyceridemia/epidemiology , Triglycerides
3.
Appl Radiat Isot ; 201: 110998, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37639969

ABSTRACT

A new-designed measurement device for radon and thoron activity concentration is developed based on gas direct measurement to support their in-situ calibration. It consists of a 2000 mm2 Passivated Implanted Planar Silicon (PIPS) detector, a Multi-Channel Analyzer (MCA), a Micro Controller Unit (MCU), and a small electrostatic chamber with a volume of nearly 23 ml. The device records those alpha particles emitted from radon and thoron gas, and the detection efficiency and the crosstalk factor of 218Po/216Po are determined by Monte Carlo simulation. Measurement results have been compared with AlphaGUARD DF2000 in pure radon and thoron environments, respectively. Results show that the measurement results of the devices and the reference monitor agree well with each other, with an average relative deviation of 0.48% for radon gas from about 3300 Bq/m3 to 38 kBq/m3 and -3.25% for thoron gas from about 25 kBq/m3 to 70 kBq/m3. Uncertainty assessment has also been done, and a relative system uncertainty of radon is about 6.8%, while that of thoron is nearly 7.3%.

4.
Bull Exp Biol Med ; 175(3): 404-409, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37561375

ABSTRACT

We studied the possibility of conductometric measurement of myelokaryocyte content in the red bone marrow of mice using a hematological Abacus Junior 5 Vet analyzer (Diatron). Statistical, correlation, and regression analyses were performed to assess of the results of myelokaryocyte counting in the suspensions of mouse red bone marrow by a direct method in cytometers and by using Abacus Junior 5 Vet analyzer. It was shown that in both intact mice and animals with modelled red bone marrow hypoplasia, irrespectively of the state of hematopoiesis in representative samples, conductometric measurements of myelokaryocyte content on the Abacus analyzer with high confidence reproduced direct counting results (in different tests p=0.64-0.82, p=0.83-0.98). This indicates that myelokaryocyte counting on the Abacus Junior 5 Vet analyzer can be an acceptable alternative to counting chamber measurements in mouse samplings. However, the variability of single measurements with the Abacus Junior 5 Vet in red bone marrow suspensions is high (5%) and this has to be considered in small samples.


Subject(s)
Bone Marrow , Hematology , Mice , Animals , Suspensions , Bone Marrow Cells , Hematopoiesis
5.
J Clin Lipidol ; 17(2): 255-260, 2023.
Article in English | MEDLINE | ID: mdl-36858936

ABSTRACT

BACKGROUND: Individuals with FH develop cardiovascular disease due to lifelong cumulative exposure to elevated LDL-C. Effective screening for FH is not yet established. OBJECTIVE: To evaluate the practicability of a FH screening by measuring directly the LDL-C in preschoolers. METHODS: LDL-C measurement through capillary blood sampling during the compulsory routine check-ups by the pediatrician in children aged 2 to 6 years including information on family history as dyslipidemia and/or premature cardiovascular disease in first and second grade of pedigrees. RESULTS: 15,009 children (52.2% males, median age 3.9 years [IQR 3.0-5.1]) participated in the study. Positive family history for hyperlipidemia was stated in 40.9% cases, in 12.0% also in at least one 1st degree relative. In the total cohort, median LDL-C was 93 mg/dL [IQR 79-109 mg/dL]. Boys had significantly higher LDL-C levels than girls (p < 0.0001), whereas there was no difference regarding their age (p = 0.757). Children from families with a positive history for hypercholesterolemia/dyslipidemia had significantly higher LDL-C levels (p < 0.001) and were more frequently among those with LDL-C values above 135 mg/dL (3.5 mmol/L, 96th percentile; 53.2% vs. 40.3%, p < 0.001) and those with LDL-C levels above 160 mg/dL (4.1 mmol/L, 99th percentile; 45.3% vs. 40.7%, p < 0.001) than children without positive family history. CONCLUSIONS: Direct measurement of LDL-C levels in children at ages 2-6 years during the compulsory routine check-ups as well as at any voluntary visits to the pediatrician's office is practicable and delivers reliable information, which can be used for a FH screening strategy in the general population.


Subject(s)
Cardiovascular Diseases , Dyslipidemias , Hypercholesterolemia , Hyperlipoproteinemia Type II , Male , Child , Female , Humans , Child, Preschool , Cholesterol, LDL
6.
Physiol Behav ; 263: 114113, 2023 05 01.
Article in English | MEDLINE | ID: mdl-36764423

ABSTRACT

This invited review is based on a presentation given at the Annual Meeting of the Society for the Study of Ingestive Behavior in July 2022 and provides the summary of two recent studies on changes in ingestive behavior following bariatric surgery (BS). First, long-term changes in daily absolute and relative macronutrient intake are reported in a rodent model of Roux-en-Y gastric bypass (RYGB). Rats undergoing RYGB progressively decreased their daily calorie- and daily fat intake compared to their preoperative baseline and to the intake of sham operated animals. Second, postbariatric changes in the within-meal ingestive microstructure are portrayed, based on longitudinal data collected in RYGB patients using a drinkometer. The post-RYGB meal size showed a dynamic adjustment process, with the highest decrease in the early postoperative phase, followed by a steady convalescence up to 1-year, at which point the meal size of RYGB patients became comparable to the normal weight adults'. Results are contextualized and contrasted to recent reports on the effect of BS on taste and food choices and consumption. The showcased evidence supports the role of ingestive adaptation and learning in the achievement of reduced calorie intake after RYGB, both in humans and in rodents. The reorganized upper-gastrointestinal anatomy supposedly leads to increased postingestive caloric sensibility, which might be an important behavioral mediator of decreased postbariatric meal size and consequent weight loss.


Subject(s)
Bariatrics , Gastric Bypass , Humans , Adult , Rats , Animals , Feeding Behavior , Eating , Energy Intake , Gastric Bypass/methods , Nutrients
7.
Circ Econ Sustain ; : 1-18, 2022 Aug 03.
Article in English | MEDLINE | ID: mdl-35966037

ABSTRACT

To halve per capita global food waste by 2030, policies and programs that effectively reduce household food waste generation are needed. Building upon a previous randomized controlled trial, this study evaluated the long-term effectiveness of the "Reduce Food Waste, Save Money" household food waste reduction intervention by comparing direct measurements of household food waste generated by treatment (n = 47) and control households (n = 52) over three time periods. The results indicate that there has been a long-term, sustained 30% reduction of avoidable food waste sent to landfill by treatment households following the implementation of this intervention. Additionally, this study assessed the impact of pandemic circumstances on the quantity and composition of household food waste by comparing direct measurements of food waste generated by the same households before (October 2017) and during (June 2020) the COVID-19 pandemic. During the first wave of the pandemic in Ontario, Canada, study households (n = 99) sent 2.98 kg of food waste to landfill per week, of which 54% was classified as avoidable food waste, and the remaining 46% as unavoidable food waste. During the pandemic, the generation of unavoidable food waste significantly increased by 65% (p < 0.01). There were also significant changes to the composition of wasted food, including a 78% increase in avoidable fruit and vegetables (p < 0.01), a 228% increase in avoidable other food (p < 0.01), and an 84% increase in unavoidable other food (p = 0.02).

8.
Clin Oral Investig ; 26(11): 6531-6538, 2022 Nov.
Article in English | MEDLINE | ID: mdl-35796801

ABSTRACT

OBJECTIVES: Gingival phenotype is closely related to treatment success and aesthetic results in the maxillary anterior region. Several methods were proposed to measure the dimensions of the gingival tissue. This study aimed to evaluate the gingival thickness using clinical and radiographic techniques and to explore the association between gingival thickness and gingival phenotypes classified by color-coded phenotype probes. MATERIALS AND METHODS: The gingival thickness of 86 periodontally healthy maxillary anterior teeth was assessed using transgingival probing (TGP) and cone-beam computed tomography (CBCT). The gingival phenotype was classified as thin, medium, thick, or very thick by transparency of the color-coded probes through the gingival sulcus. The labial alveolar bone thickness was measured on CBCT images. The keratinized tissue width (KTW) was recorded. RESULTS: Good to excellent agreement was found between TGP and CBCT regarding the thickness of the gingiva (p<0.001). There was a very high correlation between the phenotypes determined by color-coded probes and the gingival thickness measured by TGP (r=0.953, p<0.001). KTW was significantly higher in thick and very thick phenotype groups compared with thin phenotype group. CONCLUSION: Cone-beam computed tomography images and the probe transparency method with color-coded probes are reliable for identifying the gingival phenotype in the maxillary anterior region, based on comparisons to direct transgingival probing. CLINICAL RELEVANCE: The assessment of the gingival phenotype is essential, especially in the aesthetic zone, to obtain predictable and favorable clinical outcomes in various dental procedures. The newly introduced color-coded probes comprise a non-invasive and reliable method for this.


Subject(s)
Gingiva , Maxilla , Gingiva/diagnostic imaging , Maxilla/diagnostic imaging , Esthetics, Dental , Cone-Beam Computed Tomography/methods , Tooth Crown
9.
Biology (Basel) ; 11(6)2022 Jun 19.
Article in English | MEDLINE | ID: mdl-35741453

ABSTRACT

The colour of the silicone enclosure of an implantable reflectance-based optical probe plays a critical role in sensor performance. Red-coloured probes that are highly reflective to near-infrared light have been found to increase photodetector power by a factor of 6 for wavelengths between 660 and 950 nm and triple the magnitude of measured cardiac pulsations compared to traditional black probes. The increase in photodetector power and cardiac pulsation magnitude is presumably due to increased spatial range resulting from a higher magnitude of superficial tissue scattering. Conversely, probes with highly absorbent colours such as black and blue result in more stable signals and are expected to have higher spatial resolution and depth of penetration.

10.
Socioecon Plann Sci ; 82: 101110, 2022 Aug.
Article in English | MEDLINE | ID: mdl-35721381

ABSTRACT

The COVID-19 pandemic may have amplified the environmental, social, and economic implications of household food waste. A better understanding of household food wasting during the pandemic is needed to improve the management of waste and develop best practices for municipal waste management programs under crisis circumstances. A waste composition study was undertaken with 100 single-family households across the city of London, Ontario, Canada to determine the quantity and composition of household food waste disposed in June 2020, during the first wave of the COVID-19 pandemic. This study examines how household demographic, socioeconomic, and neighbourhood food environment characteristics influence household food wasting. On average, each household sent 2.81 kg of food waste to landfill per week, of which 52% was classified as avoidable food waste and 48% as unavoidable food waste. The quantity and composition of household food waste was found to be strongly influenced by the number of people and children in a household, and somewhat influenced by socioeconomic factors and neighbourhood food environment characteristics, including the availability, density, and proximity of retail food outlets.

11.
Chemosphere ; 303(Pt 1): 135021, 2022 Sep.
Article in English | MEDLINE | ID: mdl-35598787

ABSTRACT

To be able to gauge the health risks and biological effects of e-waste fires, it is of key importance to know what types and amounts of chemicals are released when they occur. In this case study, we pumped 6-24 L of air from an accidental fire at a recycling depot through a Tenax-TA tube and conducted comprehensive (non-targeted) analysis by thermal desorption/comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (TD/GC × GC/ToFMS). A special focus was placed on the search for halogenated compounds. More than 5000 components were detected in the atmosphere around the fire; however, component separation was insufficient, even when using GC × GC. The number of organohalogen compounds retrieved was increased about 1.8-fold by the refinement process of the exact mass spectrum using mass defect filtering (MDF) software. After processed by MDF, 386 peaks were concluded to be halogenated compounds. The major retrieved substances included chlorinated (or chlorinated-brominated) dioxins, chlorinated (or brominated) phenols, benzene, and various other halogenated aromatic compounds. Direct comparison of mass spectra was carried out to investigate the potential for qualitative and quantitative comparison of detected peaks without specific identification. The approximate quantitative values are summarized for each compound in the estimated substance group. Their ratios were estimated to be halogenated phenols: 13%, benzenes: 9.6%, dibenzo-p-dioxins: 9.6%, dibenzofurans: 8.4%, biphenyls; 7.4% and toluenes: 6.4%.


Subject(s)
Dioxins , Fires , Dioxins/analysis , Gas Chromatography-Mass Spectrometry/methods , Organic Chemicals/analysis , Phenols/analysis
12.
Sensors (Basel) ; 22(3)2022 Jan 25.
Article in English | MEDLINE | ID: mdl-35161682

ABSTRACT

The feasibility of a scheme in which the concentration of CO2 in gas-liquid solution is directly measured based on PZT piezoelectric-photoacoustic spectroscopy was evaluated. The existing device used for the measurement of gas concentration in gas-liquid solution has several limitations, including prolonged duration, loss of gas, and high cost due to the degassing component. In this study, we developed a measuring device in order to solve the problems mentioned above. Using this device, how the intensity of the photoacoustic signal changes with the concentration of CO2 was demonstrated through experiment. The impact that variation of the laser modulation frequency has on the photoacoustic signal was also studied. Furthermore, the experimental data generated from measuring the concentration of CO2 in gas-liquid solution was verified for a wide range of concentrations. It was found that, not only can the error rate of the device be less than 7%, but the time of measurement can be within 60 s. To sum up, the scheme is highly feasible according to the experimental results, which makes measurement of the concentration of a gas in gas-liquid solution in the future more straightforward.

13.
J Appl Clin Med Phys ; 22(8): 255-264, 2021 Aug.
Article in English | MEDLINE | ID: mdl-34272814

ABSTRACT

A realistic X-ray energy spectrum is essential for accurate dose calculation using the Monte Carlo (MC) algorithm. An energy spectrum for dose calculation in the radiation treatment planning system is modeled using the MC algorithm and adjusted to obtain acceptable agreement with the measured percent depth dose (PDD) and off-axis ratio. The simulated energy spectrum may not consistently reproduce a realistic energy spectrum. Therefore, direct measurement of the X-ray energy spectrum from a linac is necessary to obtain a realistic spectrum. Previous studies have measured low photon fluence directly, but the measurement was performed with a nonclinical linac with a thick target and a long target-to-detector distance. In this study, an X-ray energy spectrum from a clinical linac was directly measured using a NaI(Tl) scintillator at an ultralow dose rate achieved by adjusting the gun grid voltage. The measured energy spectrum was unfolded by the Gold algorithm and compared with a simulated spectrum using statistical tests. Furthermore, the PDD was calculated using an unfolded energy spectrum and a simulated energy spectrum was compared with the measured PDD to evaluate the validity of the unfolded energy spectrum. Consequently, there was no significant difference between the unfolded and simulated energy spectra by nonparametric, Wilcoxon's rank-sum, chi-square, and two-sample Kolmogorov-Smirnov tests with a significance level of 0.05. However, the PDD calculated from the unfolded energy spectrum better agreed with the measured compared to the calculated PDD results from the simulated energy spectrum. The adjustment of the incident electron parameters using MC simulation is sensitive and takes time. Therefore, it is desirable to obtain the energy spectrum by direct measurement. Thus, a method to obtain the realistic energy spectrum by direct measurement was proposed in this study.


Subject(s)
Particle Accelerators , Photons , Computer Simulation , Humans , Monte Carlo Method , Radiography , X-Rays
14.
Waste Manag ; 122: 71-80, 2021 Mar 01.
Article in English | MEDLINE | ID: mdl-33486305

ABSTRACT

Food waste management in Korea has become increasingly important as the country continues to champion the transition into a circular economy among the OECD countries to achieve sustainable development target goals. However, reliable primary data on food waste quantity and composition to achieve its prevention and managementtargets by understanding food waste patterns among Korean households is poorly documented. This study investigates the quantity and composition of food waste generation rates among the sampled households by considering two important influencing factors of seasonality and housing types in the Buk-gu province of Daegu, South Korea. The food waste generation rates from three different housing types during four representative seasons were assessed, considering the availability of different food types at different seasons. The identified 46 food waste items from sampled data were statistically analyzed using the Kruskal-Wallis statistical test. The results showed that food waste generation rates were 0.88 ± 0.37 kg/household/day (0.26 ± 0.11 kg/capita/day), which varied seasonally. Significant seasonal variations (P < 0.002) in food waste generated from the selected housing types were shown by K-W mean rank analysis. The food waste generation rate followed the seasonal order of summer > autumn > winter > spring. The effect of housing type was also a pivotal factor affecting the food waste generation. This study adds to the ground-level insights of food waste generation trends in different seasons and housing types of Korea.


Subject(s)
Refuse Disposal , Waste Management , Family Characteristics , Food , Republic of Korea
15.
Front Public Health ; 9: 813058, 2021.
Article in English | MEDLINE | ID: mdl-35155360

ABSTRACT

OBJECTIVE: Facial anthropometric data is important for the design of respirators. Two-dimensional (2D) photogrammetry has replaced direct anthropometric method, but the reliability and accuracy of 2D photogrammetry has not been quantified. This study aimed to assess inter-rater reliability of 2D photogrammetry and to examine the reliability and accuracy of 2D photogrammetry with direct measurement. DESIGN: A cross-sectional study. SETTING: Malaysia. PARTICIPANTS: A subset of 96 participants aged 18 and above. PRIMARY AND SECONDARY OUTCOMES: Ten facial dimensions were measured using direct measurement and 2D photogrammetry. An assessment of inter-rater reliability was performed using intra-class correlation (ICC) of the 2D images. In addition, ICC and Bland-Altman analyses were used to assess the reliability and agreement of 2D photogrammetry with direct measurement. RESULTS: Except for head breadth and bigonial breadth, which were also found to have low inter-rater reliability, there was no significant difference in the inter-rater mean value of the 2D photogrammetry. The mean measurements derived from direct measurement and 2D photogrammetry were mostly similar. However, statistical differences were noted for two facial dimensions, i.e., bizygomatic breadth and bigonial breadth, and clinically the magnitude of difference was also significant. There were no statistical differences in respect to the remaining eight facial dimensions, where the smallest mean difference was 0.3 mm and biggest mean difference was 1.0 mm. The ICC showed head breadth had poor reliability, whilst Bland-Altman analyses showed seven out of 10 facial dimensions using 2D photogrammetry were accurate, as compared to direct measurement. CONCLUSION: Only certain facial measurements can be reliably and accurately measured using 2D photogrammetry, thus it is important to conduct a reliability and validation study before the use of any measurement methods in anthropometric studies. The results of this study also suggest that 2D photogrammetry can be used to supplement direct measurement for certain facial dimensions.


Subject(s)
Imaging, Three-Dimensional , Photogrammetry , Cross-Sectional Studies , Face , Humans , Imaging, Three-Dimensional/methods , Photogrammetry/methods , Reproducibility of Results
16.
J Clin Monit Comput ; 35(2): 245-258, 2021 Apr.
Article in English | MEDLINE | ID: mdl-32815042

ABSTRACT

Estimating intraoperative blood loss is one of the daily challenges for clinicians. Despite the knowledge of the inaccuracy of visual estimation by anaesthetists and surgeons, this is still the mainstay to estimate surgical blood loss. This review aims at highlighting the strengths and weaknesses of currently used measurement methods. A systematic review of studies on estimation of blood loss was carried out. Studies were included investigating the accuracy of techniques for quantifying blood loss in vivo and in vitro. We excluded nonhuman trials and studies using only monitoring parameters to estimate blood loss. A meta-analysis was performed to evaluate systematic measurement errors of the different methods. Only studies that were compared with a validated reference e.g. Haemoglobin extraction assay were included. 90 studies met the inclusion criteria for systematic review and were analyzed. Six studies were included in the meta-analysis, as only these were conducted with a validated reference. The mixed effect meta-analysis showed the highest correlation to the reference for colorimetric methods (0.93 95% CI 0.91-0.96), followed by gravimetric (0.77 95% CI 0.61-0.93) and finally visual methods (0.61 95% CI 0.40-0.82). The bias for estimated blood loss (ml) was lowest for colorimetric methods (57.59 95% CI 23.88-91.3) compared to the reference, followed by gravimetric (326.36 95% CI 201.65-450.86) and visual methods (456.51 95% CI 395.19-517.83). Of the many studies included, only a few were compared with a validated reference. The majority of the studies chose known imprecise procedures as the method of comparison. Colorimetric methods offer the highest degree of accuracy in blood loss estimation. Systems that use colorimetric techniques have a significant advantage in the real-time assessment of blood loss.


Subject(s)
Blood Loss, Surgical , Bias , Humans
17.
Zhonghua Jie He He Hu Xi Za Zhi ; 43(11): 953-957, 2020 Nov 12.
Article in Chinese | MEDLINE | ID: mdl-33137862

ABSTRACT

Objective: To establish a noninvasive method for measuring upper airway critical closing pressure (Pcrit), so as to evaluate collapsibility of the upper airway during sleep. Methods: Pcrit was determined through the use of a noninvasive positive/negative pressure (CPAP/CPNP) ventilator(with independent intellectual property rights) during stageⅡ of non-rapid eye movement sleep. For the direct measurement, Pcrit was the pressure below which the upper airway occluded. For the indirect measurement, nasal pressure was plotted against maximum inspiratory flow (Vimax), and linear regression was used to interpolate the pressure (i.e., Pcrit) at which zero flow occurred. Pcrit was attained from 19 subjects without obstructive sleep apnea syndrome(OSAS), and the correlation between direct and indirect measurement methods was analyzed. Results: Directly measured and indirectly measured Pcrit showed no significant difference [(-7.02±2.74 vs (-7.26±2.96) cmH2O, 1 cmH2O=0.098 kPa; t=1.667, P>0.05] and had a highly significant correlation (r=0.986, P=0.000). Bland-Altman analysis revealed that the mean between-method difference was (0.24±0.53) cmH2O, and 95% limits of agreement ranged from -0.80 to 1.27 cmH2O, and all points except one were within limits of agreement. Conclusion: Pcrit derived from the direct and indirect measurement methods does not differ, and both methods could be used for evaluating the upper airway collapsibility.


Subject(s)
Pharynx , Sleep Apnea, Obstructive , Continuous Positive Airway Pressure , Humans , Polysomnography , Sleep , Sleep Apnea, Obstructive/diagnosis
18.
J Cardiovasc Magn Reson ; 22(1): 33, 2020 05 14.
Article in English | MEDLINE | ID: mdl-32404159

ABSTRACT

BACKGROUND: 3D-time resolved flow (4DF) cardiovascular magnetic resonance (CMR) with retrospective analysis of atrioventricular valve regurgitation (AVVR) allows for internal validation by multiple direct and indirect methods. Limited data exist on direct measurement of AVVR by 4DF CMR in pediatric congenital heart disease (CHD). We aimed to validate direct measurement of the AVVR jet as accurate and reliable compared to the volumetric method (clinical standard by 2D CMR) and as a superior method of internal validation than the annular inflow method. METHODS: We identified 44 consecutive patients with diverse CHD referred for evaluation of AVVR by CMR. 1.5 T or 3 T scanners, intravenous contrast, and a combination of parallel imaging and compressed sensing were used. Four methods of measuring AVVR volume (RVol) were used: volumetric method (VOL; the clinical standard) = stroke volume by 2D balanced steady-state free precession - semilunar valve forward flow (SLFF); annular inflow method (AIM) = atrioventricular valve forward flow [AVFF] - semilunar valve net flow (SLNF); and direct measurement (JET). AVFF was measured using static and retrospective valve tracking planes. SLFF, SLNF, AVFF, and JET were measured by 4DF phase contrast. Regurgitant fraction was calculated as [RVol/(RVol+SLNF)]× 100. Statistical methods included Spearman, Wilcoxon rank sum test/Student paired t-test, Bland Altman analysis, and intra-class coefficient (ICC), where appropriate. RESULTS: Regurgitant fraction by JET strongly correlated with the indirect methods (VOL and AIM) (ρ = 0.73-0.80, p < 0.001) and was similar to VOL with a median difference (interquartile range) of - 1.5% (- 8.3-7.2%; p = 0.624). VOL had weaker correlations with AIM and JET (ρ = 0.69-0.73, p < 0.001). AIM underestimated RF by 3.6-6.9% compared to VOL and JET, p < 0.03. Intra- and inter- observer reliability were excellent for all methods (ICC 0.94-0.99). The mean (±standard deviation) inter-observer difference for VOL was 2.4% (±5.1%), p < 0.05. CONCLUSIONS: In a diverse cohort of pediatric CHD, measurement of AVVR using JET is accurate and reliable to VOL and is a superior method of internal validation compared to AIM. This study supports use of 4DF CMR for measurement of AVVR, obviating need for expert prospective prescription during image acquisition by 2D CMR.


Subject(s)
Heart Defects, Congenital/diagnostic imaging , Hemodynamics , Image Interpretation, Computer-Assisted , Magnetic Resonance Imaging , Mitral Valve Insufficiency/diagnostic imaging , Mitral Valve/diagnostic imaging , Tricuspid Valve Insufficiency/diagnostic imaging , Tricuspid Valve/diagnostic imaging , Adolescent , Age Factors , Child , Child, Preschool , Female , Heart Defects, Congenital/physiopathology , Heart Defects, Congenital/surgery , Humans , Male , Mitral Valve/physiopathology , Mitral Valve Insufficiency/physiopathology , Observer Variation , Predictive Value of Tests , Reproducibility of Results , Retrospective Studies , Tricuspid Valve/physiopathology , Tricuspid Valve Insufficiency/physiopathology , Young Adult
19.
J Agromedicine ; 25(2): 210-220, 2020 04.
Article in English | MEDLINE | ID: mdl-31517593

ABSTRACT

Objectives: Low back disorders (LBD) are the most common musculoskeletal disorder among farmers, and awkward trunk postures such as repetitive bending are often cited as a contributor. However, it is not clear whether trends of increasing mechanization in agriculture may be impacting the requirement for trunk-intensive tasks. This study compared the patterns of working trunk posture among prairie farmers during both machine-intensive and non-intensive work days.Methods: Forty-nine adult farm workers from 22 farms participated in this study. Individual and farm characteristics were documented via questionnaire. Trunk angles and velocities were measured with an I2M inertial sensor placed on the chest. Participants completed electronic posture assessments during up to three regular work days throughout the growing season for a total of 91 electronic posture measurements. Forward and lateral trunk bending patterns were expressed in three domains: magnitude, duration, and frequency.Results: Working tasks were categorized into driving, manual, and mixed. Driving was the most commonly measured task (52% of work days), and mixed tasks the least (12%). Both 90th percentile trunk flexion-extension angles and velocities were significantly higher for manual as compared to driving tasks. Participants spent 38% of their working time in trunk forward flexion ≥ 20°, which, according to previous epidemiological studies, may increase their risk for LBD.Conclusion: The directly-measured trunk posture exposure patterns in this study suggest that machinery-intensive workdays result in less awkward trunk posture and lower velocities. Increasing mechanization invites more research on the exposures associated with machinery operation and increasing automation.


Subject(s)
Agricultural Workers' Diseases/epidemiology , Farmers/statistics & numerical data , Low Back Pain/epidemiology , Posture , Adult , Aged , Aged, 80 and over , Agricultural Workers' Diseases/physiopathology , Female , Humans , Low Back Pain/physiopathology , Male , Middle Aged , Occupational Exposure , Young Adult
20.
Waste Manag ; 101: 18-27, 2020 Jan 01.
Article in English | MEDLINE | ID: mdl-31586873

ABSTRACT

A survey, based on an expanded Theory of Planned Behavior (TPB), was used to indirectly measure self-reported food wasting and its behavioral determinants. This was complemented with directly and objectively measured food waste in curbside garbage samples. Households (n = 189) reported throwing out avoidable food waste a mean of 5.48 times (SD = 5.58) and 6.63 portions (SD = 6.61) the week prior to completing the survey. These same households threw out a mean of 2,783 g/week of food waste (SD = 2,664) in a curbside garbage sample, with 63.27% of this consisting of avoidable food waste. There were weak to fair correlations between self-reported and curbside food waste samples. The direction and level of significance of all correlations of TPB behavioral determinants with self-reported and curbside food waste samples were similar, although the correlation coefficients were higher for self-reported food wasting. A linear regression (R2 = 0.34, p < 0.001) on self-reported avoidable food waste frequency demonstrated that it was significantly (p < 0.05) associated with perceived behavioral control, personal attitude, number of people per household, gender and employment status. This was contrasted with a linear regression (R2 = 0.19, p < 0.001) on curbside avoidable food waste which was also significantly (p < 0.05) associated with perceived behavioral control and number of people per household, but also housing tenure type (owner-occupancy vs tenancy) and the good provider identity. In general, self-reported results should be used with caution as they may underestimate food waste disposal and consideration should be given to supplement, if not replace, them with direct measurement of food waste disposal.


Subject(s)
Garbage , Refuse Disposal , Attitude , Food , Self Report , Surveys and Questionnaires
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