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1.
World J Clin Cases ; 12(19): 3752-3759, 2024 Jul 06.
Article in English | MEDLINE | ID: mdl-38994321

ABSTRACT

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a common mental and behavioral disorder among children. AIM: To explore the focus of attention deficit hyperactivity disorder parents and the effectiveness of early clinical screening. METHODS: This study found that the main directions of parents seeking medical help were short attention time for children under 7 years old (16.6%) and poor academic performance for children over 7 years old (12.1%). We employed a two-stage experiment to diagnose ADHD. Among the 5683 children evaluated from 2018 to 2021, 360 met the DSM-5 criteria. Those diagnosed with ADHD underwent assessments for letter, number, and figure attention. Following the exclusion of ADHD-H diagnoses, the detection rate rose to 96.0%, with 310 out of 323 cases identified. RESULTS: This study yielded insights into the primary concerns of parents regarding their children's symptoms and validated the efficacy of a straightforward diagnostic test, offering valuable guidance for directing ADHD treatment, facilitating early detection, and enabling timely intervention. Our research delved into the predominant worries of parents across various age groups. Furthermore, we showcased the precision of the simple exclusion experiment in discerning between ADHD-I and ADHD-C in children. CONCLUSION: Our study will help diagnose and guide future treatment directions for ADHD.

2.
Sensors (Basel) ; 24(13)2024 Jul 02.
Article in English | MEDLINE | ID: mdl-39001078

ABSTRACT

This paper investigates a 1.7 mm diameter ultra-weak fiber Bragg grating (UWFBG) hydrophone towed array cable for acoustic direction finding. The mechanism of the underwater acoustic waves received by this integrated-coating sensitizing optical cable is deduced, and it is shown that the amplitude of its response varies with the direction of the sound wave. An anechoic pool experiment is carried out to test the performance of such a hydrophone array. The test array is a selection of six sensing fibers, each of which is coiled into 9 cm diameter fiber ring suspended in the water to receive acoustic signals. An average sensitivity of -141.2 dB re rad/µPa at frequencies from 2.5 kHz to 6.3 kHz was achieved, validating the detection of the azimuth of underwater acoustic waves. The ultra-thin towing cable system, with free structure, high sensitivity, and underwater target-detection capability has demonstrated great potential for future unmanned underwater vehicle (UUV) applications.

3.
Crit Rev Biotechnol ; : 1-20, 2024 Jul 14.
Article in English | MEDLINE | ID: mdl-39004513

ABSTRACT

Microbial-based bio-refining promotes the development of a biotechnology revolution to encounter and tackle the enormous challenges in petroleum-based chemical production by biomanufacturing, biocomputing, and biosensing. Nevertheless, microbial metabolic homeostasis is often incompatible with the efficient synthesis of bioproducts mainly due to: inefficient metabolic flow, robust central metabolism, sophisticated metabolic network, and inevitable environmental perturbation. Therefore, this review systematically summarizes how to optimize microbial metabolic homeostasis by strengthening metabolic flux for improving biotransformation turnover, redirecting metabolic direction for rewiring bypass pathway, and reprogramming metabolic network for boosting substrate utilization. Future directions are also proposed for providing constructive guidance on the development of industrial biotechnology.

4.
Front Hum Neurosci ; 18: 1357900, 2024.
Article in English | MEDLINE | ID: mdl-38974482

ABSTRACT

Recent works point to the importance of emotions in special-numerical associations. There remains a notable gap in understanding the electrophysiological underpinnings of such associations. Exploring resting-state (rs) EEG, particularly in frontal regions, could elucidate emotional aspects, while other EEG measures might offer insights into the cognitive dimensions correlating with behavioral performance. The present work investigated the relationship between rs-EEG measures (emotional and cognitive traits) and performance in the mental number line (MNL). EEG activity in theta (3-7 Hz), alpha (8-12 Hz, further subdivided into low-alpha and high-alpha), sensorimotor rhythm (SMR, 13-15 Hz), beta (16-25 Hz), and high-beta/gamma (28-40 Hz) bands was assessed. 76 university students participated in the study, undergoing EEG recordings at rest before engaging in a computerized number-to-position (CNP) task. Analysis revealed significant associations between frontal asymmetry, specific EEG frequencies, and MNL performance metrics (i.e., mean direction bias, mean absolute error, and mean reaction time). Notably, theta and beta asymmetries correlated with direction bias, while alpha peak frequency (APF) and beta activity related to absolute errors in numerical estimation. Moreover, the study identified significant correlations between relative amplitude indices (i.e., theta/beta ratio, theta/SMR ratio) and both absolute errors and reaction times (RTs). Our findings offer novel insights into the emotional and cognitive aspects of EEG patterns and their links to MNL performance.

5.
Sci Rep ; 14(1): 16217, 2024 Jul 13.
Article in English | MEDLINE | ID: mdl-39003403

ABSTRACT

In the study of urban development, it is very important to evaluate the influence of production factors reasonably and efficiently for the region to achieve efficient development. The principal aim of this investigation is to amalgamate the conventional measurement model characterized by robust interpretability with the non-parametric model characterized by limited interpretability, thereby enhancing the precision of research outcomes. Towards this objective, the study employs an optimized directional distance function integrated with a global Malmquist-Luenberger index to formulate a comprehensive total factor productivity measurement framework. In elucidating the homogeneous attributes of regions, departing from prior methodologies reliant on manual or direct algorithmic partitioning, this paper employs the K-means clustering algorithm for index discernment, abstracting the concept of K-means clustering centroids to encapsulate regional homogeneity, thereby delineating results through the visualization of regional development potential maps and the evolution of centroid-based clustering trend maps. The findings of the investigation illuminate common patterns of change across disparate regions, proposing a strategy for leveraging regional resource endowments towards a cohesive framework, thereby transcending constraints imposed by production efficiency limitations. Amidst the backdrop of the COVID-19 pandemic, this study draws upon provincial-level data spanning from 2000 to 2018 in China. The conclusive analytical outcomes underscore the pivotal role of energy factors in regional development efficiency, particularly within high-potential development regions, followed by the capital and labor factors. Concurrently, the study discerns a discernible hierarchical pattern among areas of development potential, which exhibits correlation with factor mobility dynamics.

6.
Med Biol Eng Comput ; 2024 Jul 15.
Article in English | MEDLINE | ID: mdl-39008187

ABSTRACT

The mechanics of the trabecular bone is related to its structure; this work aimed to propose a simple projection method to clarify the correlation between the principal mechanical direction (PMD) and the principal microstructural direction (PMSD) of trabecular bones from osteoporotic femoral heads. A total of 529 trabecular cubes were cropped from five osteoporotic femoral heads. The micro computed tomography (µCT) sequential images of each cube were first projected onto the three Cartesian coordinate planes to have three overlapped images, and the trabecular orientation distribution in the three images was analyzed. The PMSD corresponding to the greatest distribution frequency of the trabecular orientation in the three images was defined. Then, the voxel finite element (FE) models of the cubes were reconstructed and simulated to obtain their compliance matrices, and the matrices were subjected to transversal rotation to find their maximum elastic constants. The PMD corresponding to the maximum elastic constant was defined. Subsequently, the correlation of the defined PMSD and PMD was analyzed. The results showed that PMSD and PMD of the trabecular cubes did not show a significant difference at the xy- and yz-planes except that at the zx-plane. Despite this, the mean PMSD-PMD deviations at the three coordinate planes were close to 0°, and the PMSD-PMD fitting to the line PMSD = PMD demonstrated their high correlation. This study might be helpful to identify the loading direction of anisotropic trabecular bones in experiments by examining the PMSD and also to guide bone scaffold design for bone tissue repair.

7.
J Xray Sci Technol ; 2024 Jul 04.
Article in English | MEDLINE | ID: mdl-38995759

ABSTRACT

BACKGROUND: Low-dose computed tomography (CT) has been successful in reducing radiation exposure for patients. However, the use of reconstructions from sparse angle sampling in low-dose CT often leads to severe streak artifacts in the reconstructed images. OBJECTIVE: In order to address this issue and preserve image edge details, this study proposes an adaptive orthogonal directional total variation method with kernel regression. METHODS: The CT reconstructed images are initially processed through kernel regression to obtain the N-term Taylor series, which serves as a local representation of the regression function. By expanding the series to the second order, we obtain the desired estimate of the regression function and localized information on the first and second derivatives. To mitigate the noise impact on these derivatives, kernel regression is performed again to update the first and second derivatives. Subsequently, the original reconstructed image, its local approximation, and the updated derivatives are summed using a weighting scheme to derive the image used for calculating orientation information. For further removal of stripe artifacts, the study introduces the adaptive orthogonal directional total variation (AODTV) method, which denoises along both the edge direction and the normal direction, guided by the previously obtained orientation. RESULTS: Both simulation and real experiments have obtained good results. The results of two real experiments show that the proposed method has obtained PSNR values of 34.5408 dB and 29.4634 dB, which are 1.2392-5.9333 dB and 2.828-6.7995 dB higher than the contrast denoising algorithm, respectively, indicating that the proposed method has good denoising performance. CONCLUSIONS: The study demonstrates the effectiveness of the method in eliminating strip artifacts and preserving the fine details of the images.

8.
Sci Total Environ ; 946: 174380, 2024 Jun 29.
Article in English | MEDLINE | ID: mdl-38950632

ABSTRACT

Laboratory experiments are conducted in a wave flume to investigate the effect of water waves on the transport of plastic pellets over a rippled bottom. The horizontal velocities of plastic debris are analyzed over the rippled bottom for different wave conditions and plastic elements with different properties. Laboratory investigations determined the characteristic transport patterns of wave-induced plastic debris with a density of ∼2.0g/cm3 moving along the rippled bottom. In the first, swing-type motion, the grains move only in the ripple trough with velocities lower than 0.10 m/s. For sliding-type movement, the grains move along the entire rippled surface with velocities in the range of 0.10-0.13 m/s. For higher velocities in the range of 0.15-0.20 m/s, a saltation-type motion becomes dominant. The results show that plastic grains may move up to 2-3 cm above the ripple crest depending on hydrodynamic conditions. The analysis shows that for velocity-skewed flows, sliding-type motion and onshore transport dominate. For acceleration-skewed flows, saltation-type motion and offshore transport dominate, which is attributed to higher boundary layer thickness and phase lag effects. The analysis of the relationship between the particle Reynolds number and the thickness of the turbulent boundary layer reveals that for values of Rep≥1000 and a boundary layer thickness mm saltation-type motion becomes dominant. The direction of transport is affected not only by the density of the sediment and the wave skewness coefficients but also by the dimensions of the bottom ripples. The laboratory investigations also provide insight into the hydrodynamic conditions affecting the transport of plastic debris along the bottom covered with ripples in oscillating nonlinear water flows.

9.
Materials (Basel) ; 17(13)2024 Jul 03.
Article in English | MEDLINE | ID: mdl-38998360

ABSTRACT

Photoisomerizable molecules in liquid crystals (LCs) allow for photoinduced phase transitions, facilitating applications in a wide variety of photoresponsive materials. In contrast to the widely investigated azobenzene structure, research on the photoinduced phase-transition behavior of imine-based LCs is considerably limited. We herein report the thermal and photoinduced phase-transition behaviors of photoisomerizable imine-based LC dimers with twist-bend nematic (NTB) phases. We synthesize two homologous series of ester- and thioether-linked N-(4-cyanobenzylidene)aniline-based bent-shaped LC dimers with an even number of carbon atoms (n = 2, 4, 6, 8, and 10) in the central alkylene spacers, namely, CBCOOnSBA(CN) and CBOCOnSBA(CN), possessing oppositely directed ester linkages, C=OO and OC=O, respectively. Their thermal phase-transition behavior is examined using polarizing optical microscopy and differential scanning calorimetry. All dimers form a monotropic NTB phase below the temperature of the conventional nematic (N) phase upon cooling. Remarkably, the NTB phases of CBCOOnSBA(CN) (n = 2, 4, 6, and 8) and CBOCOnSBA(CN) (n = 6 and 8) supercool to room temperature and vitrify without crystallization. In addition, the phase-transition temperatures and entropy changes of CBCOOnSBA(CN) are lower than those of CBOCOnSBA(CN) at the same n. Under UV light irradiation, the NTB and N phases transition to the N and isotropic phases, respectively, and reversibly return to their initial LC phases when the UV light is turned off.

10.
Heliyon ; 10(13): e33462, 2024 Jul 15.
Article in English | MEDLINE | ID: mdl-39027486

ABSTRACT

This study examines the intellectual framework research in bank lending and technological innovation relationships in countries with high banking system liquidity. This study employs bibliometrics with R-studio tools and procedures to analyze documents regarding productions, collaborations, keyword occurrences, conceptual structure, and density and centrality occurrence's network. Combining data from the Web of Science and Scopus databases, this study obtained 939 documents from 527 sources with a significant opportunity for further elevation through combination with other themes. The development analysis based on the most related countries indicates that researchers from other countries have also conducted studies identified as having significant banking liquidity. Topic development and thematic evolution show that research on the role of bank lending on technological innovation evolves to environmental issues, with green credit as the most recent and emerging elaboration. For further direction, keywords in investment clusters can help elevate education, commerce, and impact clusters by combining them with research on government taxation, credit provision, sustainable development, and emission control themes.

11.
Heliyon ; 10(13): e33772, 2024 Jul 15.
Article in English | MEDLINE | ID: mdl-39027621

ABSTRACT

In-depth analysis of the factors affecting the transformation of resource-based cities can provide effective support for the transformation and development of resource-dependent regions. How to comprehensively identify the factors affecting the transformation of resource-based cities is a complex problem. This study starts from the total factor productivity model and focuses on the two core basic factors that affect the transformation process of cities reliant on resources. Economic benefits and energy efficiency, respectively, from the economic benefit analysis framework and energy efficiency analysis framework for reconstruction, the two frameworks are combined with the use of distorted prices of resource elements to solve the problem that the synergistic effect of economic benefits and energy efficiency can not be measured. In order to quantitatively analyze the factors that affect the development efficiency of cities reliant on resources under the single or synergistic effect of the comprehensive framework, this study optimizes the directional distance function from three perspectives: exogenous weight, direction vector endogeneity, and absolute distance transformation relative distance, thus achieving an accurate assessment transformation efficiency of cities reliant on resources. Considering the impact of the new coronavirus epidemic, this study only selected the data of resource-based cities from 2003 to 2018, and found through model calculation that the impact on the transformation of cities reliant on resources: (1) Labor mismatch is mainly achieved by affecting the structure about the production of resource-based enterprises and industrial human resources; (2) Capital mismatch is mainly realized by affecting the production of resource-based enterprises; (3) Energy mismatch is mainly achieved by affecting high energy consumption enterprises and low production technology level enterprises. Further research shows that the main objects of these factors are the four parts of production technology level, energy consumption, total factor productivity and industrial structure. Through these contents, they affect environmental efficiency and deeply affect the transformation process of resource-based cities.

12.
Biol Sport ; 41(3): 119-127, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38952902

ABSTRACT

This study aimed to compare the effects of two elastic band 10-week training programmes on the athletic performance in adolescent female handball players. Participants aged 16.0 ± 0.5 years were randomly assigned to control (CNT, n = 12), standard elastic band (SEB, n = 12), or contrast elastic band (CEB, n = 12) programmes, each performed twice a week supplementing the regular training. The sprint (10 m and 20 m), modified Illinois change-of-direction test (COD), squat jump (SJ), countermovement jump (CMJ), standing long jump (SLJ), back extensor strength (BES), medicine ball throw (MBT), 1-RM bench press, 1-RM half squat, repeated sprint ability, and force-velocity (F-V) tests were measured before and after the intervention. Both CEB and SEB similarly improved sprint (p < 0.01 and p < 0.01) and COD (p < 0.001 and p < 0.01) when compared to CNT. Jumping performance improved significantly (SJ p < 0.01; CMJ p < 0.05) only in CEB, compared to CNT. Strength improved in both experimental groups (p < 0.01; ES: 0.73 < d < 1.59) compared to CNT, and there was a greater increase for CEB than SEB (p < 0.05) in the medicine ball throw (Table 3). Both CEB and SEB increased all RSA scores compared to CNT (p < 0.01; ES: 0.10 < d < 1.22), without significant difference between them. All F-V scores increased significantly in CEB and SEB compared to CNT (p < 0.01; ES: 0.45 < d < 2.47). In addition, CEB showed substantial gains in performance for PPabs, PPrel, and F0 (p < 0.001, p < 0.001 and p < 0.05, respectively) compared to SEB. Ten-week elastic band training conducted within the competitive season improved limb strength, power and F-V profile in female handball players, with a superior effect of the contrast elastic band training mode for upper-limb strength and F-V characteristics.

13.
Chemosphere ; : 142873, 2024 Jul 15.
Article in English | MEDLINE | ID: mdl-39019187

ABSTRACT

Electro-osmosis has been valued as a promising technology to enhance the dewatering of waste sludge, stabilization and environmental remediation of soils with low permeability. However, the coefficient of electro-osmotic permeability (keo) is commonly taken as constant value which is particularly not the case in variable charge soil. As a result, the nonlinearity of the electro-osmotic flow (EOF) and the direction reverse could not be interpreted. Herein, the electro-chemical parameters were monitored in electro-osmotic experiment with natural variable charge soil. It was observed that evolutions showed significant nonlinear behavior and were correlated. The comprehensive Zeta potential model proposed by the authors was applied to simulate the nonlinear keo induced by the variable pH and electrolyte concentration. The agreement between tested and simulated flow rate variation and excess pore water pressure distribution demonstrated the reliability of the theory. The error rate of the simulations through coupling nonlinear keo and voltage gradient Ex was reduced to 29.4% from 381.9% of calculations with constant parameters. The direction reverse of EOF was innovatively interpreted. Hence, the numerical model would act as a useful tool to connect these electro-chemical parameters and provide guidance to evaluate contributions of commonly used pH conditioning measurements.

14.
J Sports Sci ; : 1-11, 2024 Jul 18.
Article in English | MEDLINE | ID: mdl-39023311

ABSTRACT

The aim of our study was to compare the force steadiness and the discharge characteristics of motor units in the tibialis anterior (TA) during ankle dorsiflexion and foot adduction produced by submaximal isometric contractions with the dominant and non-dominant foot. Fifteen young men performed maximal and submaximal contractions at five target forces with both legs, and motor unit activity in TA was recorded using high-density electromyography. Maximal force and the fluctuations in force during submaximal contractions were similar between the two legs (p > 0.05). Motor unit activity was characterized by measures of mean discharge rate (MDR), coefficient of variation for interspike interval (CoV for ISI), and standard deviation of the filtered cumulative spike train (SD of fCST). There were no statistically significant differences in motor unit activity between legs during ankle dorsiflexion. In contrast, the MDR and the CoV for ISI but not the SD of fCST, were greater for the non-dominant foot compared with the dominant foot during foot adduction. Nonetheless, these differences in motor unit activity were not sufficient to influence the force fluctuations during the submaximal contractions. These results indicate that control of the force produced by TA during the two actions was not influenced by limb dominance.

15.
Front Microbiol ; 15: 1391553, 2024.
Article in English | MEDLINE | ID: mdl-38841075

ABSTRACT

Introduction: The composition and structure of natural soil are very complex, leading to the difficult contact between hydrophobic organic compounds and degrading-bacteria in contaminated soil, making pollutants hard to be removed from the soil. Several researches have reported the bacterial migration in unsaturated soil mediated by fungal hyphae, but bacterial movement in soil of different particle sizes or in heterogeneous soil was unclear. The remediation of contaminated soil enhanced by hyphae still needs further research. Methods: In this case, the migration and biodegradation of Diaphorobacter sp. LW2 in soil was investigated in presence of Pythium ultimum. Results: Hyphae could promote the growth and migration of LW2 in culture medium. It was also confirmed that LW2 was able to migrate in the growth direction and against the growth direction along hyphae. Mediated by hyphae, motile strain LW2 translocated over 3 cm in soil with different particle size (CS1, 1.0-2.0 mm; CS2, 0.5-1.0mm; MS, 0.25-0.5 mm and FS, <0.25 mm), and it need shorter time in bigger particle soils. In inhomogeneous soil, hyphae participated in the distribution of introduced bacteria, and the total number of bacteria increased. Pythium ultimum enhanced the migration and survival of LW2 in soil, improving the bioremediation of polluted soil. Discussion: The results of this study indicate that the mobilization of degrading bacteria mediated by Pythium ultimum in soil has great potential for application in bioremediation of contaminated soil.

16.
Traffic Inj Prev ; : 1-8, 2024 Jun 14.
Article in English | MEDLINE | ID: mdl-38875455

ABSTRACT

OBJECTIVE: Misjudgments of vehicle speed or distance frequently lead to collisions, particularly among older pedestrians who are less accurate in estimating vehicle speeds than younger individuals. However, comprehensive studies that assess multiple factors influencing speed perception in older pedestrians are lacking. METHODS: This research utilized computer simulations to explore how vehicle color (red, green, blue) and direction of travel (approaching or receding) affect perceived speed errors in both relative and absolute judgment scenarios among older pedestrians. RESULTS: Data from 38 older adults and 40 college students indicated that red vehicles were associated with fewer perceived speed errors than either green or blue vehicles. Errors increased for vehicles moving away, with absolute judgments showing greater discrepancies than relative ones. Analysis revealed that, across various combinations of the three independent variables-vehicle color, vehicle direction, and judgment type-the older participants exhibited significantly larger perceived speed errors compared to college students. Furthermore, the study identified significant interactions between vehicle color and direction, and between judgment type and vehicle direction. CONCLUSION: Our findings are beneficial in understanding the factors influencing older pedestrians' speed perceptions, aiding public safety and informing car design to ensure safer roads for older pedestrians.

17.
J Bodyw Mov Ther ; 39: 243-250, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38876634

ABSTRACT

BACKGROUND: Training interventions like Resisted Sled Training, Complex Training, Plyometric training, and recently, Postactivation Potentiation Enhancement (PAPE) protocols are being employed by sportsmen for performance enhancement. Currently, there is no conclusive evidence on the effectiveness of the PAPE protocols and methods to integrate them into the training. The current systematic review aims to critically summarize the current evidence on PAPE protocols' effect on Sprint and Change of Direction (COD) performance in Athletes and study the influence of the Type of PAPE protocols, Recovery duration, Volumes, and loads of PAPE protocols. METHODS: A systematic computerized literature search was performed from December 2020 to June 2022 on the databases: MEDLINE (assessed by PubMed), CENTRAL (Cochrane Library Central Register of Controlled Trials), PeDro, and Science direct. The major criteria for inclusion were Athletes (Population) who performed PAPE protocol as Intervention before Sprint and/or COD assessment tests. The studies were individually assessed for Risk of Bias using EPHPP (Effective Public Health Practice Project) Tool. RESULTS: A total of sixteen studies were included. For Linear sprint, nine studies reported a significant PAPE effect whereas, six studies reported insignificant effects. Whereas, for COD performance, two studies reported insignificant results and one study reported significant CODS enhancements The recovery duration ranged from 15 s up to 16 min. CONCLUSION: PAPE protocols can be incorporated provided the recovery duration is of Moderate duration (3-8mins) or Individualized durations, using multiple sets (2-6), moderate-high loads (>85% 1-RM), type of protocol is Barbell Hip Thrust, Plyometrics or Unilateral biomechanically similar exercises to Running.


Subject(s)
Athletic Performance , Running , Humans , Athletic Performance/physiology , Running/physiology , Plyometric Exercise/methods , Athletes , Resistance Training/methods , Muscle Strength/physiology , Physical Conditioning, Human/methods , Physical Conditioning, Human/physiology
18.
Cureus ; 16(5): e60643, 2024 May.
Article in English | MEDLINE | ID: mdl-38899255

ABSTRACT

The crystalization of the components of bile within the gallbladder can lead to the formation of gallstones (cholelithiasis), which may often require surgical removal of the gallbladder, a procedure known as cholecystectomy, in symptomatic cases. Robotic single-site cholecystectomy (RSSC) is a recently introduced groundbreaking minimally invasive procedure for gallbladder removal. RSSC utilizes robotic technology, offering enhanced dexterity through a single-incision approach, promising improved outcomes such as reduced postoperative pain and superior cosmesis. However, certain limitations, such as restricted instrument movement and heightened hernia risk, necessitate a critical evaluation of this modality. Furthermore, as the widespread adoption of RSSC remains undecided due to concerns over its costs, efficiency, and overall superiority over prior models, this paper assesses future possibilities for RSSC's evolution. In vivo robotics, improved digital imaging, and re-engineering of the surgical instruments themselves are all potential avenues to augment the current RSSC design, although it is currently unclear as to what extent they could impact the procedure's viability. This review critically examines the available literature on the effectiveness and potency of RSSC compared to its predecessors in the modern healthcare setting and proposes future directions through which innovation could more firmly establish the procedure as the standard of care for cholecystectomy.

19.
Curr Biol ; 2024 Jun 14.
Article in English | MEDLINE | ID: mdl-38901427

ABSTRACT

Sequential neuronal patterns are believed to support information processing in the cortex, yet their origin is still a matter of debate. We report that neuronal activity in the mouse postsubiculum (PoSub), where a majority of neurons are modulated by the animal's head direction, was sequentially activated along the dorsoventral axis during sleep at the transition from hyperpolarized "DOWN" to activated "UP" states, while representing a stable direction. Computational modeling suggested that these dynamics could be attributed to a spatial gradient of hyperpolarization-activated currents (Ih), which we confirmed in ex vivo slice experiments and corroborated in other cortical structures. These findings open up the possibility that varying amounts of Ih across cortical neurons could result in sequential neuronal patterns and that traveling activity upstream of the entorhinal-hippocampal circuit organizes large-scale neuronal activity supporting learning and memory during sleep.

20.
J Sports Sci ; 42(9): 814-824, 2024 May.
Article in English | MEDLINE | ID: mdl-38874271

ABSTRACT

The primary objective of this study was to investigate the relationship between metatarsophalangeal joint (MTPj) flexion torque and sprint acceleration, cutting and jumping performance, and kinetics. A secondary aim was to explore this relationship when MTP flexion strength was associated with other foot and lower limb neuromuscular outputs. After an initial MTPj flexion torque assessment using a custom-built dynamometer, 52 high-level athletes performed the following tasks on a force platform system: maximal sprint acceleration, 90-degree cutting, vertical and horizontal jumps, and foot-ankle hops. Their foot posture, foot passive stiffness and foot-ankle reactive strength were assessed using the Foot Posture Index, the Arch Height Index Measurement System and the Foot-Ankle Rebound Jump Test. Ankle plantarflexion and knee extension isometric torque were assessed using an isokinetic dynamometer. During maximal speed sprinting, multiple linear regressions suggested a major contribution of MTPj flexion torque, foot passive stiffness and foot-ankle reactive strength to explain 28% and 35% of the total variance in the effective vertical impulse and contact time. Ankle plantarflexor and quadriceps isometric torques were aggregately contributors of acceleration performance and separate contributors of cutting and jumping performance. In conclusion, MTPj flexion torque was more strongly associated with sprinting performance kinetics especially at high-speed.


Subject(s)
Acceleration , Athletic Performance , Foot , Muscle Strength , Running , Torque , Humans , Muscle Strength/physiology , Running/physiology , Athletic Performance/physiology , Foot/physiology , Young Adult , Male , Biomechanical Phenomena , Metatarsophalangeal Joint/physiology , Kinetics , Female , Ankle/physiology , Muscle, Skeletal/physiology , Adolescent , Adult , Posture/physiology
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