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AIM:To observe the changes in corneal aberrations and the characteristics of visual quality after transepithelial photorefractive keratectomy(T-PRK)and femtosecond small incision lenticule extraction(SMILE)in the correction of low myopia.METHODS: Prospective cohort study. A total of 32 cases(32 eyes)with low myopia who underwent T-PRK surgery and 45 cases(45 eyes)of SMILE surgery at Weifang Eye Hospital from April 2021 to April 2022 were selected. The uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), spherical equivalent(SE), corneal higher-order aberrations(HOAs)and objective visual quality were compared between the two groups.RESULTS:All patients completed the surgery successfully without complications such as infection. At 3mo postoperatively, the safety index was 1.13±0.16 and 1.16±0.17(P=0.48)and the efficacy index was 1.10±0.20 and 1.15±0.18(P=0.27)in the T-PRK and SMILE groups, respectively. The percentage of UCVA(LogMAR)≤0 in the T-PRK and SMILE groups was 94% and 98%, respectively. The percentage of the residual SE within ±0.5D was 88% and 87% in the two groups, respectively. The HOAs and spherical aberration in both groups were significantly increased(P≤0.01), and the increase was not statistically significant between the two groups(P=0.31, 0.89). There was no significant change in horizontal coma, horizontal trefoil and vertical trefoil in both groups(P>0.05). The vertical coma in SMILE group was significantly increased(P<0.001), while there was no significant change in T-PRK group(P>0.05), and the increase was significantly greater in SMILE group than in T-PRK group(P<0.001). There was no significant difference in objective scattering index(OSI), modulation transfer function cut off frequency(MTFcut off), Strehl ratio(SR), visual acuity(VA)100%, VA20% and VA9% between the two groups(P>0.05).CONCLUSION:Both T-PRK and SMILE showed good safety, efficacy, and visual quality in correcting low myopia, while SMILE induced more vertical coma than T-PRK.
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@#AIM: To evaluate the clinical efficacy of the posterior chamber intraocular lens(ICL)implantation for high myopia by the double-pass optical quality analysis system II(OQAS II).<p>METHODS: A total of 26 eyes of 52 patients with high myopia admitted to the First Affiliated Hospital of Anhui Medical University from December 2017 to December 2018 were selected. All patients underwent ICL implantation. Follow-up to obtain the best corrected visual acuity(BCVA)of all patients. And a series of parameters, such as uncorrected visual acuity(UCVA), object scatter index(OSI), modulation transfer function(MTF), Strehl ratio(SR)and Predicted VA of 100%,20% and 9%,were obtained before and 1wk,1 and 3mo after operation.<p>RESULTS: Compared with preoperative UCVA and BCVA, the 1wk, 1 and 3mo UCVA were better than preoperative and gradually improved, and the differences were statistically significant(<i>P</i><0.01). Compared with OSI, MTF, SR and Predicted VA 100%, 20% and 9% before operation, the situation improved at 1wk,1 and 3mo after operation, with statistical significance(<i>P</i><0.01).<p>CONCLUSION: ICL implantation can effectively correct high myopia and improve UCVA. Through OQAS II analysis, OSI was reduced after ICL implantation. The postoperative MTF, SR and Predicted VA of 100%, 20% and 9% higher than those before surgery. The visual quality of patients with high myopia was improved after ICL implantation.
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@#AIM: To compare the visual quality between implantable collamer lens(ICL)implantation and FS-LASIK for correcting moderate and high myopia.<p>METHODS: Prospective study. Choose in June 2018 to December 2018 for ICL implantation of 58 patients(116 eyes)and 48 patients(96 eyes)underwent FS-LASIK. The diopter, visual acuity and visual quality of the two groups before and after surgery were analyzed and compared.<p>RESULTS: After 3mo operation, the degree of spherical mirror in the ICL group was higher than that in the FS-LASIK group(0.19±0.22D <i>vs</i> 0.09±0.29D, <i>P</i><0.05), but there was no difference in visual acuity, lenticule degree and spherical equivalent between the two groups(<i>P</i>>0.05). The modulation transfer function cut off frequency(MTF cut off), objective scatter index(OSI)and OV9% were significantly better in the ICL group than in the FS-LASIK group, while the SR was lower than the FS-LASIK group. Compared with the former, the MTF cut off was significantly increased in the ICL group, the SR and OSI values were decreased, and the SR value was decreased in the FS-LASIK group(all <i>P</i><0.05).<p>CONCLUSION: Both ICL implantation and FS-LASIK can effectively improve the visual acuity and diopter of patients, ICL implantation for patients with moderate and high myopia provides relatively good visual quality.<p>
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@#AIM: To evaluate the early postoperative efficacy of SMART for myopia and compare it with TransPRK.<p>METHODS: Retrospective non-randomized controlled study. Totally 120 eyes of 60 patients with myopia who underwent SMART and TransPRK in our hospital from January to August 2018 were selected respectively. The uncorrected visual acuity(UCVA), visual quality, pain score, corneal epithelial healing and subepithelial haze were compared between two groups.<p>RESULTS: There was no statistical differences between two groups regarding the proportion of UCVA reaching or exceeding 1.0 at 5d, 1mo and 3mo after operation(<i>P</i>>0.05), but the visual quality of SMART group was better than that of TransPRK group at 5d after operation(<i>P</i><0.05), and with the prolongation of time, the visual quality of the two groups gradually improved. There was a significant difference in pain scores between the TransPRK group and SMART group(3.56±0.96 <i>vs</i> 3.07±1.07; 1.22±0.61 <i>vs</i> 0.84±0.59)on the 1st day and 3rd day after operation(<i>P</i><0.01). 5d after operation, the complete recovery rate of corneal in TransPRK group was lower than that in SMART group(69.2% <i>vs</i> 83.3%, <i>P</i><0.05). At 1st and 3 mo after operation, there was no difference in haze between the two groups(5.0% <i>vs</i> 5.0% and 8.3% <i>vs</i> 10.0%; <i>P</i>>0.05).<p>CONCLUSION: There is no significant difference between SMART and TransPRK in the speed and stability of visual acuity recovery, but the early postoperative pain of SMART is lighter, the corneal epithelium is healed faster, and the visual quality is better.
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@#AIM: To evaluate the accuracy of qualitative prediction of cataract surgery by double-pass optical quality analysis system(OQASTMⅡ).<p>METHODS: A retrospective study was conducted. Totally 57 cataract patients(67 eyes)were randomly selected from October 2018 to December 2018 in Renmin Hospital of Wuhan University. According to the objective scattering index(OSI), they were divided into group A(28 eyes, OSI>8.0), group B(28 eyes, OSI≤8.0), and group C(11 eyes, OSI could not be detected due to severe lens opacity). The effect of surgery was predicted by Predicted VA100% and preoperative BCVA.<p>RESULTS: In group A, 26 eyes(93%)comply with the standard, and in group B, 24 eyes(86%)comply with the standard. There was no significant difference between the two groups(<i>P</i>=0.669). Besides, no correlation was found between Predicted VA100% and postoperative 2wk BCVA(<i>r</i><sub>s</sub>=0.103, <i>P</i>>0.5).<p>CONCLUSION: The OQASTMⅡ system can objectively, accurately and intuitively predict the effect of cataract surgery.
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Objective: To analyze and explore the application of duable-pass optical quality analysis system(OQAS) on the evaluation of visual quality for patients with high myopia complicated with cataract who received intraocular lens implantation. Methods: The documents of 93 patients with high myopia complicated with cataract were collected in the retrospective analysis. And all of patients received ultrasonic emulsification and intraocular lens implantation. And then the visual situation and the changes of PSF, OSI, MTF, MTFcutoff, SR, OV100%, OV20%and OV9%were evaluated by using double-pass OQAS at three points included pre-operation, 1week of post-operation and 1month of post-operation. Results: After treatment, the visual situation of patients were significantly improved, and the differences of visual situations among pre-operation, 1 week of post-operation and 1 month of post operation were significant (F=6.831, P<0.05). And the differences of OSI, PSF and OV9%between the before and after treatment were significant (F=6.732, F=9.102, F=5.029, P<0.05), respectively. While the differences of MTFcutoff, SR, OV100%and OV20% between the two groups were no significant. Under the conditions of 5 cpd and 10 cpd of MTF, the differences of MTF among pre-operation, 1 week post operation and 1month post operation were significant (F=8.029, F=4.039, P<0.05), respectively. Besides, at 1 week post-operation and 1month post-operation, the differences among 5cpd, 10cpd and 15cpd were significant(F=7.829, F=6.921, P<0.05), respectively. Conclusion: After the patients with high myopia complicated with cataract receive intraocular lens implantation of ultrasonic emulsification, the visual analysis system of dual channel can preferably evaluate the visual quality of patients, and can objectively reflect aberration, scattering and diffraction, etc. Therefore, it is worthy to be popularized and applied.
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Background The incidence of myopia is gradually increasing,and how to choose a better corrective method of myopia for the best visual demand is very important.Objective This study was to compare visual quality of implantable collamer lens (ICL) implantation with femtosecond laser in situ keratomileusis (FSLASIK) for moderate and high myopia using double-pass optical quality analysis system (OQAS).Methods A non-randomized controlled clinical trail was performed.Fifty-two eyes with-4.00 to-9.00 D of 26 consecutive patients were included in NO.1 Hospital of Xi'an from January 2015 to January 2016.Twenty-four eyes of 12 patients with the corneal thickness ＜500 μm received ICL implantation as ICL group and 28 eyes of 14 patients which corneal thickness was ≥500 μm underwent FS-LASIK surgery as FS-LASIK group.The demography was matched between the two groups (all at P＞0.05).All the patients were followed-up for 3 months after surgery.The preoperative best corrected distance visual acuity (BCDVA),spherical equivalent (SE),postoperative uncorrected distance visual acuity (UCDVA),BCDVA and SE were examined and compared between two groups.The parameters from OQAS were evaluated and intergrouply compared,including the objective scattering inders (OSI),modulation transfer function (MTF) cut off frequency,Strehl ratio and OQAS values under the contrast of 100％,20％ and 9％ (OV100,OV20,OV9).Results The postoperative BCDVA was not significantly different from preoperative UCDVA in both ICL group and FS-LASIK group (-0.04±t0.10 vs.0.05±0.12;-0.07±0.12 vs.0.00±0.12) (t=3.128,2.358,both at P＞0.05).No statistically significant differnces were found in SE,UCDVA and BCDVA after operation between ICL group and FS-LASIK group (t =1.292,0.900,-0.653,all at P＞0.05).OQAS examination showed that MTF cut off,OSI,Strehl ratio,OV100 were not significantly different after operation between ICL group and FS-LASIK group (t=-2.032,-1.440,-0.224,all at P＞0.05).The postoperative OV20 and OV9 were 0.82±0.14 and 0.80±0.21 in the ICL group,which were significantly higher than those in the FS-LASIK group(0.59±0.15 and 0.47±0.13) (t =4.105,4.702,both at P＜0.05).Conclusions Both ICL implantation and FS-LASIK provide good optical and visual quality for moderate to high myopic eyes,and ICL appears to have a better visual quality in comparison with FS-LASIK under the contrasts of 20％ and 9％.
