ABSTRACT
Objective Through clinical pharmacists participating in the treatment of hip prosthesis infection, to explore the factors of Salmonella infection and skin itching, and to increase the importance of Salmonella infection and the pharmaceutical monitoring of adverse reactions of antibiotics. Methods The causes and treatment of Salmonella infection were analyzed by reviewing the literature, monitoring indicators and patient's clinical symptoms, and analyzing the cause of the patient's skin itching, to provide the patient with a reasonable anti-infective treatment plan. Results After several antibacterial drug adjustments during hospitalization, the patient's inflammatory indicators decreased, and the clinical symptoms improved. Conclusion Although the prosthetic joint infection caused by Salmonella is very rare, attention should be paid to the detection of Salmonella. At the same time, clinical pharmacists should increase the monitoring of antibiotics in their daily work.
ABSTRACT
An immunocompetent 84-year-old woman was admitted for severe neck pain with a fever. Magnetic resonance imaging showed osteitis of the dens. She had methicillin-susceptible Staphylococcus aureus bacteremia related to a dental extraction. She then developed an infection of a hip prosthesis due to the same organism. Her treatment consisted in intravenous antibiotics followed by oral suppressive antibiotic therapy for 2 years. Exchange arthroplasty was not performed given the advanced age of the patient, her unwillingness to undergo the procedure, and the risk of neurological complications during endotracheal intubation. The outcome was favorable at last follow-up more than 2 years after antibiotic treatment initiation.
