ABSTRACT
En este trabajo queremos exponer un modelo terapéutico para tratar a aquellos adolescentes quese resisten a cambiar con los abordajes terapéuticos normales. Son adolescentes que no tienen resuelta su au-tonomía personal, su diferenciación self-objeto. Para ayudar al adolescente primero tenemos que resolver suindiferenciación, su dependencia con los padres. Cuando se haya diferenciado de ellos, podrá hacerse cargo desus problemas personales.(AU)
In this paper we wantto expose a therapeutic model to treat those adolescents who resist to change with the normal therapeuticapproaches. They are adolescents who have not resolved their personal autonomy, their self-object differen-tiation. To help the adolescent we must first resolve their indifferentiation, their dependence on their parents.When they have differentiated themselves from their parents, they will be able to take charge of their personalproblems.(AU)
En aquest treball volem presentar un model terapèutic per tractar aquells adolescents que es resisteixena canviar amb els abordatges terapèutics normals. Són adolescents que no tenen resolta la seva autonomiapersonal, la seva diferenciació self-objecte. Per ajudar l'adolescent, primer hem de resoldre la indiferenciació ila dependència amb els pares. Quan se n'hagi diferenciat, es podrà fer càrrec dels seus problemes personals.(AU)
Subject(s)
Humans , Female , Child , Feeding and Eating Disorders of Childhood , Child Psychiatry , Child Development , Psychotherapy , Parenting , Psychology, Child , Child Health , PsychopathologyABSTRACT
Clinical material from the treatment of a highly destructive schizophrenic patient is used to demonstrate the role and function of therapeutic mediations in promoting transformation and symbolization. Use of the Squiggle Game as a therapeutic mediation is shown to sustain the therapeutic process and to facilitate working through of the obscure and complex dynamics commonly seen in the treatment of psychotic patients. The Squiggle Game presents a first transitional space entailing both the concreteness of psychosis and the potential for symbolization provided by psychoanalysis. The game becomes the first meeting ground for the progressive encounters of the therapeutic couple, primarily because in it the violent destructiveness of psychosis is partly deflected in a way that fosters development of the transference relationship. Step-by-step emotional transformations gained through the Squiggle Game are reported and discussed, together with the patient's need to rely on nonverbal communicative modes to bring early traumatic experiences that never reached verbalization into treatment. This working through process furthered development of the dyad's intense transference-countertransference dynamics, which stimulated construction of a link between here-and-now and there-and-then in sessions, leading to the patient's integration and a sense of the life-historical significance of her experience.
Subject(s)
Psychoanalytic Therapy , Schizophrenia/therapy , Schizophrenic Psychology , Countertransference , Humans , Object Attachment , Transference, PsychologyABSTRACT
Cancer stem cells (CSCs) comprise a tumor subpopulation responsible for tumor maintenance, resistance to chemotherapy, recurrence and metastasis. The identification of this cell group is very important, but there is still no consensus on its characterization. Several CSC markers have been described, like CD133, CD24, CD44 and ALDH1, but more research to identify new markers to facilitate the identification of CSC in a heterogeneous tumoral mass is required. Thus, this article describes the CD26 expression as a CSC marker and the role that it plays in different types of cancer. CD26 expression correlates with some characteristics of CSCs, like the formation of spheres in vitro, formation of new tumors, and resistance to chemotherapy. CD26 is therefore suggested as an auxiliary marker for CSC in different types of cancer, and as a potential therapeutic target.
