Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters











Database
Language
Publication year range
1.
Molecules ; 23(8)2018 Aug 16.
Article in English | MEDLINE | ID: mdl-30115841

ABSTRACT

Tomato crops can be affected by several infectious diseases produced by bacteria, fungi, and oomycetes. Four phytopathogens are of special concern because of the major economic losses they generate worldwide in tomato production; Clavibacter michiganensis subsp. michiganensis and Pseudomonas syringae pv. tomato, causative agents behind two highly destructive diseases, bacterial canker and bacterial speck, respectively; fungus Fusarium oxysporum f. sp. lycopersici that causes Fusarium Wilt, which strongly affects tomato crops; and finally, Phytophthora spp., which affect both potato and tomato crops. Polygodial (1), drimenol (2), isonordrimenone (3), and nordrimenone (4) were studied against these four phytopathogenic microorganisms. Among them, compound 1, obtained from Drimys winteri Forst, and synthetic compound 4 are shown here to have potent activity. Most promisingly, the results showed that compounds 1 and 4 affect Clavibacter michiganensis growth at minimal inhibitory concentrations (MIC) values of 16 and 32 µg/mL, respectively, and high antimycotic activity against Fusarium oxysporum and Phytophthora spp. with MIC of 64 µg/mL. The results of the present study suggest novel treatment alternatives with drimane compounds against bacterial and fungal plant pathogens.


Subject(s)
Anti-Bacterial Agents/chemistry , Biological Control Agents/chemistry , Fungicides, Industrial/chemistry , Sesquiterpenes/chemistry , Anti-Bacterial Agents/isolation & purification , Anti-Bacterial Agents/pharmacology , Biological Control Agents/isolation & purification , Fungicides, Industrial/isolation & purification , Fungicides, Industrial/pharmacology , Fusarium/drug effects , Solanum lycopersicum/microbiology , Phytophthora/drug effects , Plant Bark/chemistry , Plant Diseases/microbiology , Plant Diseases/therapy , Plant Extracts/chemistry , Plant Extracts/isolation & purification , Plant Extracts/pharmacology , Sesquiterpenes/isolation & purification , Tracheophyta/chemistry
SELECTION OF CITATIONS
SEARCH DETAIL