ABSTRACT
[Objective]To understand non-trauma mechanic ventilation treating acute respiratory failure of organophosphorus pesticide poisoning and observe the effect.[Method]16 cases of organophosphorus poisoning together with respiratory failure were treated with non-trauma mechanic ventilation,then observed clinical effect and blood-gas changes.[Result]15 cases got safe and went out of hospital;1 was opened thachea and died from multi-organic failure.Average machine time was 7.8 hours,before going machine:PaO243.92?7.95mmHg,SaO280.6?5.9%;after ventilation,the disease was stable,the artery blood-gas:PaO283.65?4.72mmHg,SaO296.6?4.1%.There's marked difference between them,no complications happened in treatment.[Conclusion]Mechanic ventilation is a key link in saving severe respiratory failure caused by organophosphorus poisoning.Success or not is closely related with going-machine time,meanwhile,the energy-recovery agent must be used enough and reasonably to quickly reach atropine function,as well as to strengthen trachea nursing,by these can death rate be reduced effectively for severe organophosphorus poisoning.