ABSTRACT
Optimal vitamin D status has commonly been defined as the level of 25-hydroxyvitamin D (25(OH)D) at which parathyroid hormone (PTH) concentrations would be maximally suppressed, represented by an observed minimum plateau. Previous findings indicate a large variation in this plateau, with values ranging from <30 nmol/L up to 100 nmol/L. This disparity in values might be explained by differences in study design and methodology, ethnicity, age, gender and latitude. This study aimed to investigate the concentration of 25(OH)D at which PTH concentrations were suppressed in Brazilian women living in opposite latitudes (high vs. low: i.e., UK and Brazil), during wintertime. Using data from the D-SOL study (Interaction between Vitamin D Supplementation and Sunlight Exposure in Women Living in Opposite Latitudes), the association between 25(OH)D status and PTH levels were examined in 135 Brazilian women (56 living in England and 79 living in Brazil, aged 20-59 years old). Mean PTH concentrations for Brazilian women with vitamin D deficiency (<25 nmol/L) were significantly higher compared to those with vitamin D insufficiency (25-49.9 nmol/L) (p < 0.01), vitamin D adequacy (50-74.9 nmol/L) (p < 0.01) and those with optimal vitamin D status (>75 nmol/L) (p < 0.001). Regression modelling was used to investigate the relationship between serum 25(OH)D and PTH for the sample as a whole and for each group separately. A cubic model was statistically significant for the total sample (p < 0.001), whereas a linear model presented the best fit for Brazilian women living in England (p = 0.04) and there were no statistically significant models fitted for Brazilian women living in Brazil. The cubic model suggests that 25(OH)D concentrations above 70-80 nmol/L are optimal to suppress the parathyroid gland in Brazilian women. These findings contribute to a better understanding of the relationship between 25(OH)D and PTH in populations living in a low latitude location and are of great relevance for discussions regarding the estimation of optimal cut-offs for vitamin D levels in the Brazilian population as well as for other low latitude locations.
Subject(s)
Dietary Supplements , Nutritional Physiological Phenomena/physiology , Parathyroid Hormone/blood , Vitamin D/analogs & derivatives , Vitamin D/administration & dosage , Adult , Brazil , Female , Humans , Middle Aged , Seasons , United Kingdom , Vitamin D/blood , Vitamin D Deficiency/blood , Young AdultABSTRACT
This study was conducted to determine the effects of supplemental irrigation and nitrogen fertilization on forage oat (Avena sativa, L.) productivity, variety UPF7. The experiment was a split-plot randomized block design with four replications. The experimental unit consisted of combinations of four irrigation depths applied when cumulative Classe A pan evaporation (ECA) approximately reached 30 mm, (I = 0%, I = 50%, I = 100% and I = 150% of ECA), and four nitrogen levels (N = O, N = 80, N = 160 e N = 240 kg.ha-1). The total maximum productivity of dry matter (6,9 t.ha-1) was obtained for the water depth of 319,2 mm and 152,4 kg.ha-1 of nitrogen. For the considered prices, the water and nitrogen levels that induced the maximum net income were 310 mm and 120 kg.ha-1, respectively, reaching a maximum net return of R$ 897.ha-1.
Foi realizado experimento visando estudar os efeitos da irrigação suplementar e da adubação nitrogenada na produtividade de aveia (Avena sativa L.), variedade UPF7, para ferragem. O delineamento experimental foi o de blocos ao acaso com parcelas subdivididas, com quatro repetições. Os tratamentos constaram da combinação de quatro lâminas de irrigação aplicadas quando a evaporação acumulada no tanque "Classe A" (ECA) atingia aproximadamente 30 mm (I = 0%, I = 50%, I = 100% e I = 150% de ECA) e quatro níveis de adubação nitrogenada (N = O, N = 80, N = 160 e N = 240 kg.ha-1 de nitrogênio). A máxima produtividade total de matéria seca (6,9 Lha-1) foi estimada para 319,2 mm de água e 152,4 kg.ha-1 de nitrogênio. Aos preços considerados para insumos e produto, a máxima receita líquida (R$ 897.ha-1) foi obtida para 310 mm de água e 120 kg.ha-1 de nitrogênio.
ABSTRACT
This study was conducted to determine the effects of supplemental irrigation and nitrogen fertilization on forage oat (Avena sativa, L.) productivity, variety UPF7. The experiment was a split-plot randomized block design with four replications. The experimental unit consisted of combinations of four irrigation depths applied when cumulative Classe A pan evaporation (ECA) approximately reached 30 mm, (I = 0%, I = 50%, I = 100% and I = 150% of ECA), and four nitrogen levels (N = O, N = 80, N = 160 e N = 240 kg.ha-1). The total maximum productivity of dry matter (6,9 t.ha-1) was obtained for the water depth of 319,2 mm and 152,4 kg.ha-1 of nitrogen. For the considered prices, the water and nitrogen levels that induced the maximum net income were 310 mm and 120 kg.ha-1, respectively, reaching a maximum net return of R$ 897.ha-1.
Foi realizado experimento visando estudar os efeitos da irrigação suplementar e da adubação nitrogenada na produtividade de aveia (Avena sativa L.), variedade UPF7, para ferragem. O delineamento experimental foi o de blocos ao acaso com parcelas subdivididas, com quatro repetições. Os tratamentos constaram da combinação de quatro lâminas de irrigação aplicadas quando a evaporação acumulada no tanque "Classe A" (ECA) atingia aproximadamente 30 mm (I = 0%, I = 50%, I = 100% e I = 150% de ECA) e quatro níveis de adubação nitrogenada (N = O, N = 80, N = 160 e N = 240 kg.ha-1 de nitrogênio). A máxima produtividade total de matéria seca (6,9 Lha-1) foi estimada para 319,2 mm de água e 152,4 kg.ha-1 de nitrogênio. Aos preços considerados para insumos e produto, a máxima receita líquida (R$ 897.ha-1) foi obtida para 310 mm de água e 120 kg.ha-1 de nitrogênio.