ABSTRACT
OBJECTIVE: To characterize and determine risk factors for key dimensions of well-being at hospital discharge in families of neonates with acute symptomatic seizures. STUDY DESIGN: This prospective, observational cohort study enrolled 144 parent-infant dyads among neonates with acute symptomatic seizures from 9 pediatric hospitals in the Neonatal Seizure Registry. One parent per family completed a discharge survey, which included measures of anxiety and depression, health-related quality of life, and impact on the family. Multivariable regression analyses adjusted for site were constructed to examine parent and infant characteristics associated with well-being. RESULTS: At discharge, 54% of parents reported symptoms of anxiety and 32% reported symptoms of depression. Parents of infants with hypoxic-ischemic encephalopathy reported more depression and worse quality of life than parents of infants with other seizure etiologies. Parental quality of life was also lower with greater infant age at discharge. A higher level of maternal education was associated with greater impact on the family. All these differences were medium to large effect sizes, ranging from 0.52 to 0.78. CONCLUSIONS: Symptoms of anxiety and depression are common in parents of infants with neonatal seizures, and several parent and infant characteristics are associated with poorer parental quality of life and family well-being. These findings are a call to action to improve mental health screening and services for parents of infants with neonatal seizures.
Subject(s)
Anxiety/epidemiology , Depression/epidemiology , Family Health , Parents/psychology , Quality of Life , Seizures , Acute Disease , Cohort Studies , Female , Humans , Infant, Newborn , Male , Patient Discharge , Prospective Studies , Risk FactorsABSTRACT
Accidente cerebrovascular presuntamente perinatal es la expresión utilizada para los casos en los que se diagnostica un accidente cerebrovascular antiguo por sus secuelas y no por la sintomatología aguda. Muchos accidentes cerebrovasculares presuntamente perinatales tienen como primera manifestación una hemiparesia congénita, la cual se hace notoria entre el cuarto y el octavo mes de vida como preferencia manual precoz. Es por esto por lo que la preferencia manual clara y persistente desarrollada antes del año de vida debe asumirse como un signo de alarma de una probable secuela motora. En este trabajo, revisamos la historia clínica de 15 casos de accidente cerebrovascular presuntamente perinatal para evaluar la edad en la que la consulta derivó en el diagnóstico, el motivo de consulta y la edad de desarrollo de la preferencia manual.
Presumed perinatal ischemic stroke is the term used for cases in which an old stroke is diagnosed by the consequences of it and not by the acute symptoms. Many presumed perinatal ischemic strokes have congenital hemiparesis as the first manifestation, which is usually noticed between the fourth and eighth month of life as early hand preference. That is why the clear and persistent handedness developed before one year of age must be assumed as a warning sign of probable motor sequelae. In this paper we review the medical records of 15 cases of presumed perinatal ischemic stroke to assess the age at which the consultation led to the diagnosis, reason for consultation and age at development of handedness.
Subject(s)
Humans , Infant , Child, Preschool , Child , Stroke/diagnosis , Stroke/physiopathology , Functional Laterality , Pregnancy , Age FactorsABSTRACT
Presumed perinatal ischemic stroke is the term used for cases in which an old stroke is diagnosed by the consequences of it and not by the acute symptoms. Many presumed perinatal ischemic strokes have congenital hemiparesis as the first manifestation, which is usually noticed between the fourth and eighth month of life as early hand preference. That is why the clear and persistent handedness developed before one year of age must be assumed as a warning sign of probable motor sequelae. In this paper we review the medical records of 15 cases of presumed perinatal ischemic stroke to assess the age at which the consultation led to the diagnosis, reason for consultation and age at development of handedness.
Accidente cerebrovascular presuntamente perinatal es la expresión utilizada para los casos en los que se diagnostica un accidente cerebrovascular antiguo por sus secuelas y no por la sintomatología aguda. Muchos accidentes cerebrovasculares presuntamente perinatales tienen como primera manifestación una hemiparesia congénita, la cual se hace notoria entre el cuarto y el octavo mes de vida como preferencia manual precoz. Es por esto por lo que la preferencia manual clara y persistente desarrollada antes del año de vida debe asumirse como un signo de alarma de una probable secuela motora. En este trabajo, revisamos la historia clínica de 15 casos de accidente cerebrovascular presuntamente perinatal para evaluar la edad en la que la consulta derivó en el diagnóstico, el motivo de consulta y la edad de desarrollo de la preferencia manual.