ABSTRACT
On the basis of chemical content determinationï¼ the bioassay methods can be used to comprehensively evaluate and control the Chinese medicine compound. This paper analyzed the newly published literature on traditional Chinese medicine(TCM) bioassay. The selection of standard control substances and the establishment of experimental system are the main difficulties in bioassay. At presentï¼ the standard control substances mainly includeï¼ different sources of products with basically similar componentsï¼ certified medicinal materialsï¼ genuine medicinal materialsï¼ commonly used chemical drugs or biological products with similar pharmacological functionsï¼ as well as Chinese medicine potency conversed by activity of biological products. In this paperï¼ the common bioassays would be summarized from the clinical efficacy of activating blood circulation and removing stasis and clearing heat and detoxification. It is one of the important contents in the industrial production of traditional Chinese medicine to gradually establish the bioassay platform of Chinese medicine from the enterprise's internal control to the industry. recognition.
Subject(s)
Biological Assay , Drugs, Chinese Herbal/standards , Medicine, Chinese Traditional , Quality ControlABSTRACT
On the basis of chemical content determination， the bioassay methods can be used to comprehensively evaluate and control the Chinese medicine compound. This paper analyzed the newly published literature on traditional Chinese medicine(TCM) bioassay. The selection of standard control substances and the establishment of experimental system are the main difficulties in bioassay. At present， the standard control substances mainly include： different sources of products with basically similar components， certified medicinal materials， genuine medicinal materials， commonly used chemical drugs or biological products with similar pharmacological functions， as well as Chinese medicine potency conversed by activity of biological products. In this paper， the common bioassays would be summarized from the clinical efficacy of activating blood circulation and removing stasis and clearing heat and detoxification. It is one of the important contents in the industrial production of traditional Chinese medicine to gradually establish the bioassay platform of Chinese medicine from the enterprise's internal control to the industry. recognition.
