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1.
Quintessence Int ; 0(0): 0, 2024 Jun 24.
Article in English | MEDLINE | ID: mdl-38912671

ABSTRACT

OBJECTIVE: The study aims to provide a comprehensive case analysis from a single center, with the objective of clarifying the optimal timing and recommending a preferred treatment strategy customized to the specific presentation of each type of supernumerary tooth (SNT) identified in our research. METHODS AND MATERIAL: A retrospective study was conducted on patients who presented with SNT and were treated through an interdisciplinary at the clinic. RESULTS: 55 patients with 81 SNT of the permanent dentition were analyzed. They included 30 males and 25 females. The dentition status of the patients was as follows: 31 patients with mixed dentition, 0 patients with deciduous dentition, and 24 patients with permanent dentition. The diagnosis of SNT diagnosis was primarily made by general or pediatric dentists and/or orthodontists. Patients were then referred to maxillofacial surgeons for treatment decision. The timing of treatment was mainly determined by the oral surgeon, based on the recommendations of the other specialists involved. Cases involving mal-eruption or malalignment of permanent teeth required both surgical and orthodontic treatment. Patients over 9 years old were treated either under local anesthesia or sedation, while those under 9 years old were treated under deep sedation or general anesthesia A comprehensive investigation of cases involved the utilization of cone beam computerized tomography (CBCT) at the SNT site to facilitate treatment planning. There was a significant correlation between younger age and the preference for treatment under sedation or general anesthesia (p=0.01, t-test). Similarly, a strong association was found between younger age and the need for additional orthodontic treatment (p=0.016, t-test). Cases of surgical removal of SNT at a young age typically did not require orthodontic traction of the permanent tooth, in contrast to cases of late surgical intervention (patients over 11 years old), which often did necessitate such traction. There was a strong tendency for treating supernumerary teeth (SNT) in the maxilla. The proximity of SNTs to vital anatomical landmarks significantly influenced treatment decisions. Patients with SNTs near the mental foramen or the inferior dental canal in the premolar area were exclusively placed under follow-up care (p=0.002, Pearson's chi-square test). However, in the maxilla, the proximity of SNTs to vital structures such as the floor of the nose and the incisive nerve did not affect the treatment approach, and those supernumerary teeth were mostly removed. CONCLUSIONS: A team approach for managing supernumerary teeth (SNT) is recommended. The timing of treatment should carefully consider the advantages and disadvantages of early versus late intervention. Early surgical treatment in cases where eruption is disturbed might result in spontaneous eruption, eliminating the need for orthodontic traction of the permanent teeth.

2.
Cureus ; 16(4): e57946, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38737996

ABSTRACT

Mesiodens are common supernumerary teeth that prominently erupt in the midline between the maxillary central incisors. If two or more mesiodens are present, they are termed mesiodentes, indicating the presence of multiple supernumerary teeth in the midline. These often cause aesthetic disharmony in the anterior teeth due to their abnormal position, leading to extraction in most cases and resulting in midline diastema when impacted or partially erupted. This case is uncommon, as the patient expressed a desire to preserve their mesiodens as a distinctive feature, considering them a familial trait worth retaining. The family history of the patient revealed the occurrence of mesiodens in three generations, highlighting a hereditary pattern of supernumerary teeth within the family. The endodontic therapy involving root canal treatment successfully treated the mesiodens, alleviating pain, and preserving them as desired.

3.
Radiol Case Rep ; 19(8): 3089-3095, 2024 Aug.
Article in English | MEDLINE | ID: mdl-38770383

ABSTRACT

This case report describes the treatment of a 9-year-old boy with impacted maxillary central incisors due to 2 supernumerary teeth. A sequential approach comprising of surgical removal of the supernumerary teeth and 2 stages of surgical exposure and orthodontic traction of the impacted teeth resulted in correct repositioning of incisors. Close monitoring and multidisciplinary cooperation during various stages of treatment led to a successful esthetic outcome, with optimal periodontal health and functional occlusion.

4.
BMC Oral Health ; 24(1): 572, 2024 May 17.
Article in English | MEDLINE | ID: mdl-38760743

ABSTRACT

BACKGROUND: Cleidocranial dysplasia (CCD) is an autosomal dominant hereditary disorder. Besides skeletal abnormalities, CCD is often associated with dental complications, such as multiple supernumerary teeth and permanent teeth impaction or delayed eruption. METHODS: Supernumerary teeth of axial, sagittal and coronal CBCT view was characterized in detail and 3D image reconstruction was performed. Number and location of teeth, morphology of supernumerary teeth, positional relationship between supernumerary and adjacent permanent teeth, direction of supernumerary teeth in CCD patients were analyzed. RESULTS: The mean age of the 3 CCD patients in this study was 16.7 years. Among 36 supernumerary teeth, the majority of them were identified as apical side located and lingual side located. Normal orientation was the most common type in this study, followed by sagittal orientation, and horizontal orientation. Horizontal orientation teeth were all distributed in the mandible. Supernumerary teeth exhibited significantly shorter crown and dental-root lengths, as well as smaller crown mesiodistal and buccolingual diameters (P < 0.01). There was no difference in the number of supernumerary teeth between the maxilla and mandible, and the premolars region had the largest number of supernumerary teeth and the incisor region had the smallest number. CONCLUSIONS: This study compares number and location of teeth, morphology of supernumerary teeth, positional relationship between supernumerary and adjacent permanent teeth and direction of supernumerary teeth, this study also provides a reference for the comprehensive evaluation of CCD patients before surgery.


Subject(s)
Cleidocranial Dysplasia , Cone-Beam Computed Tomography , Imaging, Three-Dimensional , Tooth, Supernumerary , Humans , Cleidocranial Dysplasia/diagnostic imaging , Cleidocranial Dysplasia/complications , Tooth, Supernumerary/diagnostic imaging , Imaging, Three-Dimensional/methods , Adolescent , Male , Female , Tooth Crown/diagnostic imaging , Tooth Crown/abnormalities , Tooth Crown/pathology , Tooth Root/diagnostic imaging , Tooth Root/abnormalities , Odontometry/methods , Young Adult , Mandible/diagnostic imaging , Mandible/abnormalities , Bicuspid/abnormalities , Bicuspid/diagnostic imaging , Maxilla/diagnostic imaging , Image Processing, Computer-Assisted/methods
5.
Cureus ; 16(3): e55385, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38562341

ABSTRACT

Supernumerary teeth are presented in any region of the dental arches as additional teeth to the standard set of teeth and may present in either the primary or secondary dentition. They can be found as single or multiple teeth on one or both sides of the dental arches, with a preference for the premaxilla. The supernumerary teeth might cause aesthetic and/or functional problems, mainly if situated in the maxillary anterior region. Multiple supernumerary teeth are often related to specific conditions or in syndromic patients, i.e., cleft palate, cleft lip, cleidocranial dysplasia, and Gardner's syndrome. This report presents a case of an eight-year-old female patient with non-syndromic bilateral supernumerary teeth in the primary and secondary dentition. The patient is medically fit, and her family history was non-contributory.

6.
J Orthod ; : 14653125241239057, 2024 Mar 23.
Article in English | MEDLINE | ID: mdl-38520320

ABSTRACT

The aim of this case series was to illustrate the development of late-forming supernumerary teeth (LFST) and highlight the implications for orthodontic treatment. There are limited studies relating to the aetiology, prevalence and treatment of LFST and the cases presented here demonstrate the management of LFST within a tertiary care centre. Five cases are presented, which show various presentations and chronological ages in the development of LFST. This case series emphasises the significance of maintaining a low threshold for suspecting LFST in patients where supernumerary teeth have previously been identified. It also highlights the importance of regular clinical and radiographic reviews. Timely identification can help prevent complications and optimise treatment outcomes.

7.
Children (Basel) ; 11(3)2024 Mar 19.
Article in English | MEDLINE | ID: mdl-38539401

ABSTRACT

An observational study was carried out in a teaching hospital in Saudi Arabia to determine the occurrence of dental anomalies among Arabian children. The study included children of Saudi nationality with primary teeth. The study assessed the prevalence of dental anomalies in their primary dentition. The assessment and data collection were conducted by a single examiner, utilizing clinical examination and intra-oral radiographs. A comparative analysis was conducted to examine dental anomalies in relation to gender (boys and girls) and arch type (maxillary and mandibular). In addition, the study explored the occurrence of gender-specific dental anomalies depending on arch type. The data analysis was conducted using IBM Statistics (version 21.0) with a significance level of p < 0.05. In total, there were 245 children included in the final analysis. The study population consisted of boys (66%) and girls (34%), with an average age of 4.87 ± 0.9 years. Taurodontism was the most prevalent dental abnormality, occurring in 2.8% of the individuals in the study sample. The study sample exhibited hypodontia in 2%, supernumerary teeth in 2.4%, double teeth in 2%, and microdontia in 1.2%. Talon cusp and macrodontia have a relatively low incidence of 0.4%. Boys exhibit supernumerary teeth, microdontia, macrodontia, talon cusp, and taurodontism, whereas hypodontia and double teeth were more frequent in girls.

8.
J Clin Pediatr Dent ; 48(2): 204-208, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38548651

ABSTRACT

Impacted supernumerary teeth are defined as the presence of one or more teeth in a patient's upper and lower jaws in addition to the normal number of teeth in the dental arch. It has an incidence rate of approximately 1%-14% and more frequently occurs in males than females, may be single or multiple, unilateral or bilateral, erupted or impacted. In this article, we describe the case of a patient with two supernumerary teeth between the roots of the mandibular second premolar and the first molar, which influenced the effectiveness of the first orthodontic treatment. The special anatomical position of the complex supernumerary teeth made tooth extraction challenging. Given the higher risk status of surgery, we implemented a novel tooth extracting technique for this patient. Thus, in this study, we describe a case of minimally invasive extraction of bilateral mandibular impacted supernumerary teeth using a digital 3D positioning guide plate.


Subject(s)
Tooth, Impacted , Tooth, Supernumerary , Male , Female , Humans , Tooth, Supernumerary/diagnostic imaging , Tooth, Supernumerary/surgery , Tooth, Impacted/diagnostic imaging , Tooth, Impacted/surgery , Mandible/surgery , Tooth Extraction/adverse effects , Tooth Extraction/methods , Bicuspid
9.
BMC Oral Health ; 24(1): 397, 2024 Mar 28.
Article in English | MEDLINE | ID: mdl-38549071

ABSTRACT

OBJECTIVES: This study aimed to summarize the clinical features of non-syndromic late developing supernumerary teeth (LDST) and comparisons with common supernumerary teeth (ST) and explore the association between LDST and the third dentition. MATERIALS AND METHODS: This study retrospected cone-beam computed tomography (CBCT) and medical history of 41,903 consecutive patients from January to December 2021. Comparisons between ST and LDST were evaluated by Chi-square test or Fisher exact test. Correlation between chronological age and dental stage age was evaluated by Spearman's rank correlation coefficient. Binary logistic regression analysis was used to explore the features of LDST originating from the third dentition. RESULTS: Sixty patients with 126 non-syndromic LDST and 1602 patients with 1988 non-syndromic ST were identified. The prevalence of ST and LDST was 3.82% and 0.14%, respectively, with a male-female ratio of 1.78:1 and 1.31:1. LDST patients mainly had LDST in multiple (58.33%) and bilaterally (41.67%), with an average of 2.1/patient. Most LDST were normal-shaped (84.13%), vertically oriented (71.43%), located in the mandible (80.16%), and distributed in the premolar region (82.54%). The study also indicated that the development of LDST was correlated with permanent teeth, with LDST developing 6.48 to 10.45 years later. In this study, 72.22% of LDST met the clinical criteria for the third dentition. CONCLUSIONS: LDST manifested different clinical features from common ST. LDST might be closely related to the third dentition. CLINICAL RELEVANCE: This work would help to comprehend LDST from a clinical perspective, and may be complementary to the criteria of the third dentition.


Subject(s)
Tooth, Supernumerary , Humans , Male , Female , Tooth, Supernumerary/diagnostic imaging , Tooth, Supernumerary/epidemiology , Dentition , Dentition, Permanent , Bicuspid , Cone-Beam Computed Tomography
10.
J Maxillofac Oral Surg ; 23(1): 75-80, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38312968

ABSTRACT

Background: The early detection of impacted teeth is essential for the prevention of future malocclusions and possible lesions. The aim of this study is to assess the prevalence of impacted teeth and associated pathological lesions. Methods: One thousand six hundred and two panoramic radiographs were analyzed for this retrospective study. The prevalence of impacted teeth, the presence of supernumerary teeth and cystic or tumoral lesions associated, and the type of angulation of third molars using Winter's classification were accessed. The descriptive statistics and the Chi-squared test were performed (P < 0.05). Results: One thousand three hundred and ninety-seven panoramic radiographs fulfilled impacted criteria. A prevalence of 541 (38.7%) impacted teeth was observed, with the female gender significantly higher (P < 000.1). Of the total impacted teeth (n = 541), the overall mean impacted of lower third molars was 55.6%. Twenty-nine (5.3%) supernumerary teeth and four lesions were verified. The angulations most observed in the upper (76.6%) and lower (39.2%) third molars were vertical (P < 000.1) and mesioangulated (P < 000.1), respectively. Conclusion: The impacted tooth prevalence was 38.7%, more common in females than in males. The lower third molars presented the highest prevalence of impacted, and the most common angulations were vertical and mesioangulated. Only four associated lesions were observed.

11.
Cureus ; 16(1): e51611, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38313948

ABSTRACT

This case study offers a rare and difficult condition involving the impaction of teeth 11, 12, and 13, providing a severe dental challenge. A thorough examination was performed on the patient, which included clinical evaluations and radiographic examinations. Because the impacted teeth were causing discomfort and functional impairment, a multidisciplinary approach was required, which included surgical exposure followed by traction forces to level and align the impacted teeth. The abstract emphasizes the case's complexity, digging into the diagnosis process and the establishment of a personalized treatment strategy. The complexities of handling many impacted teeth are explored in length, including surgical intervention, orthodontic considerations, and postoperative care.

12.
Cureus ; 16(1): e53056, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38410302

ABSTRACT

Supernumerary molars are an uncommon anomaly that can occur in the maxillofacial complex, referring to the presence of additional teeth in the dental arch. This condition is often associated with several rare disorders such as Gardner's syndrome, Cleidocranial dysplasia, Ehler-Danlos syndrome, and Down syndrome However, it is seldom observed in non-syndromic associations. They occur more frequently in the maxilla than in the mandible. This research represents a unique case study that explores unerupted paramolar and parapremolar follicles coexisting in both the maxillary and mandibular arches of a 17-year-old male patient. The discovery of these follicles was fortuitous, as the patient exhibited no symptoms during the initial orthopantomogram scan. Despite the absence of noticeable symptoms, vigilant monitoring and observation were employed over time. Subsequently, a substantial shift in the approach to management occurred with the integration of surgical and orthodontic methodologies, guided eruption strategies, and a collaborative, multidisciplinary effort.

13.
Cureus ; 16(1): e52699, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38384613

ABSTRACT

Noonan syndrome (NS) is a common congenital syndrome characterized by multiple anomalies commonly observed in children. In this article, we describe a case of a patient with congenital heart disease, severe mitral regurgitation, and Nonaan syndrome presented with left maxillary swelling and pain, which was treated by complete surgical excision of the left maxillary odontoma. Based on this case, we conclude that numerous oral abnormalities may be related to NS and thus necessitate interdisciplinary treatment planning and prompt therapy. The importance of including oral manifestations as a scoring criterion in diagnosing NS cannot be overstated, as the significance of oral findings in NS has largely been overlooked.

14.
Int Dent J ; 74(3): 566-572, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38290916

ABSTRACT

OBJECTIVE: Dental anomalies (DA) can affect paediatric patients' aesthetics, function, and psychological well-being. There is a lack of data about the prevalence of DA in children in Kuwait. This study aimed to investigate the prevalence and distribution of DA amongst schoolchildren aged 8 to 12 years. METHODS: A retrospective study was conducted using panoramic digital radiographs of children who attended a single dental center. All radiographs were evaluated by 2 calibrated and trained examiners. RESULTS: DA were present in 110 (20.1%) out of the 546 panoramic radiographs examined: 53.6% in females and 46.4% in males. The mean age of children with DA (9.83 ± 1.29) was similar to that of children with no anomalies (9.96 ± 1.46). The most prevalent anomaly was dental agenesis (9.3%), followed by taurodontism (6.6%) and ectopic eruption (EE, 2%). DA were more common in the maxilla (58.2%) compared to the mandible (41.8%, P = .042). Congenitally missing teeth were significantly more frequent in the mandible (56.9%) than in the maxilla (43.1%, P = .003). EE was significantly more common in the maxilla (90.9%) than in the mandible (9.1%, P = .024). Microdontia and root dilacerations were only present in males, whilst supernumerary teeth, transposition, and impacted teeth were noted in females only. CONCLUSIONS: The prevalence of DA amongst schoolchildren in Kuwait was considered to be relatively high. Certain DA were associated with gender. The significant prevalence of DA highlights the need for early diagnosis using panoramic radiographs, particularly during the ages of 9 and 10, in order to ensure effective patient management.


Subject(s)
Radiography, Panoramic , Tooth Abnormalities , Humans , Kuwait/epidemiology , Male , Female , Child , Prevalence , Retrospective Studies , Tooth Abnormalities/epidemiology , Anodontia/epidemiology , Tooth Eruption, Ectopic/epidemiology , Maxilla/abnormalities , Mandible/abnormalities , Dental Pulp Cavity/abnormalities
15.
Diagnostics (Basel) ; 13(23)2023 Nov 29.
Article in English | MEDLINE | ID: mdl-38066804

ABSTRACT

We present a very rare case of a child with nine supernumerary teeth to analyze the potential, benefits, and limitations of artificial intelligence, as well as two commercial tools for tooth segmentation. Artificial intelligence (AI) is increasingly finding applications in dentistry today, particularly in radiography. Special attention is given to models based on convolutional neural networks (CNN) and their application in automatic segmentation of the oral cavity and tooth structures. The integration of AI is gaining increasing attention, and the automation of the detection and localization of supernumerary teeth can accelerate the treatment planning process. Despite advancements in 3D segmentation techniques, relying on trained professionals remains crucial. Therefore, human expertise should remain key, and AI should be seen as a support rather than a replacement. Generally, a comprehensive tool that can satisfy all clinical needs in terms of supernumerary teeth and their segmentation is not yet available, so it is necessary to incorporate multiple tools into practice.

16.
J Pharm Bioallied Sci ; 15(Suppl 1): S810-S813, 2023 Jul.
Article in English | MEDLINE | ID: mdl-37654282

ABSTRACT

The present case report illustrates a rare occurrence of multiple dental anomalies in a healthy 12-year-old patient including anomalies of shape and number of teeth. The developmental dental anomalies noticed in the present case scenario are dens invaginatus, taurodontism, radix entomolaris, supernumerary teeth, and pulp stones seen in multiple teeth. It is not rare to notice these anomalies individually, but their combination is rare in a single, non-syndromic patient. This report also signifies the importance of thorough extra-intra-oral and radiographic examinations of patients with dental anomalies.

17.
Ear Nose Throat J ; : 1455613231186953, 2023 Aug 08.
Article in English | MEDLINE | ID: mdl-37551771

ABSTRACT

Objectives: Among oral surgical conditions, supernumerary teeth of the dental arch is quite common. However, supernumerary teeth in the nasal cavity is a rarity and their diagnosis and treatment have not yet been systematized. We therefore examined the literature on intranasal supernumerary teeth to establish systematic methods for their diagnosis and treatment. Methods: Using the PubMed database, we searched for literature on intranasal supernumerary teeth, published from 1990 to 2019. We combined 131 cases identified in the literature with 1 case that we experienced and summarized the characteristics of 132 cases. We recorded data on sex, age, reason for consultation (chief complaint), reporting department, impact classification, surgical approach, and anesthesia. Results: Males outnumbered females in all decades evaluated. The median age of patients was 10 years. The characteristics of these cases resembled those of maxillary anterior supernumerary teeth. The most common reason for consultation in earlier years was nasal symptoms; however, over time, an increasing number of patients sought consultation due to indications in diagnostic imaging. The most common reporting department in all decades was Otolaryngology. However, reports from Departments of Oral Surgery became increasingly common over time. General anesthesia was applicable for all impaction positions and surgical methods used. Local anesthesia was performed only with the nasal method. Of the 132 patients, 4 experienced no effect from local anesthesia, which was then changed to general anesthesia. Intranasal supernumerary teeth were found to possess the same characteristics as impacted maxillary central supernumerary teeth. Conclusions: The increased use of computed tomography has enabled early detection in asymptomatic cases. Classifying intranasal supernumerary teeth by their vertical and horizontal impaction positions provides an accurate grasp of supernumerary tooth impact classification and the selection of suitable methods of surgery and anesthesia, thus enabling systematic diagnosis and treatment of intranasal supernumerary teeth.

18.
J Stomatol Oral Maxillofac Surg ; : 101525, 2023 Jun 02.
Article in English | MEDLINE | ID: mdl-37271261

ABSTRACT

PURPOSE: This study aimed to describe clinical and imaging analysis of supernumerary teeth in the mandibular region of 22 cases. STUDY DESIGN: Retrospective study METHODS: : This study enrolled patients diagnosed with supernumerary teeth who underwent cone beam computed tomography (CBCT) at Stomatology Hospital of Xi'an Jiaotong University from August 2016 to September 2022. Participants included individuals aged 7-29 years of both genders. The following variables were examined: number of supernumerary teeth, location, shape, direction, length, relationship with adjacent teeth and surrounding anatomical structures, and secondary effects RESULTS: : Out of 236 subjects, 22 (6.02%) were found to have supernumerary teeth in the mandibular region, with a total of 62 teeth identified. The male-to-female ratio was 5:6. Most supernumerary teeth were located in the lingual side of the mandibular region, particularly in the 34-35 tooth area (21.66%), followed by the 44-45 tooth region. The vast majority of supernumerary teeth (96.77%) were impacted, and more than half (51.67%) were located near the mental nerve canal. The average length of the supernumerary teeth was 10.5 mm. While no primary complications were observed, some secondary symptoms were noted, such as the ectopic eruption of adjacent teeth and crowding of permanent teeth. CONCLUSION: The supernumerary teeth in the mandibular area have regional characteristics, which can provide for clinical diagnosis and treatment. CBCT can accurately analyze the location of supernumerary teeth and their secondary effects, and provides the treatment plan on that basis.

19.
SAGE Open Med Case Rep ; 11: 2050313X231169854, 2023.
Article in English | MEDLINE | ID: mdl-37151740

ABSTRACT

Supernumerary teeth and taurodontism are both common dental anomalies when found as isolated entities. However, simultaneous presence in the same individual without a syndrome is rarely reported in the literature. This case report describes a 20-year-old non-syndromic male with multiple supernumerary teeth in association with multiple molar and premolar taurodonts and no family history of genetic predisposing factors. Taurodontism was measured and confirmed through cone-beam computed tomography for accuracy of the classification. Early diagnosis with the aid of radiographic imaging and persistent follow-up are crucial to treatment.

20.
BMC Oral Health ; 23(1): 314, 2023 05 23.
Article in English | MEDLINE | ID: mdl-37221585

ABSTRACT

BACKGROUND: Nance-Horan syndrome (NHS; MIM 302,350) is an extremely rare X-linked dominant disease characterized by ocular and dental anomalies, intellectual disability, and facial dysmorphic features. CASE PRESENTATION: We report on five affected males and three carrier females from three unrelated NHS families. In Family 1, index (P1) showing bilateral cataracts, iris heterochromia, microcornea, mild intellectual disability, and dental findings including Hutchinson incisors, supernumerary teeth, bud-shaped molars received clinical diagnosis of NHS and targeted NHS gene sequencing revealed a novel pathogenic variant, c.2416 C > T; p.(Gln806*). In Family 2, index (P2) presenting with global developmental delay, microphthalmia, cataracts, and ventricular septal defect underwent SNP array testing and a novel deletion encompassing 22 genes including the NHS gene was detected. In Family 3, two half-brothers (P3 and P4) and maternal uncle (P5) had congenital cataracts and mild to moderate intellectual deficiency. P3 also had autistic and psychobehavioral features. Dental findings included notched incisors, bud-shaped permanent molars, and supernumerary molars. Duo-WES analysis on half-brothers showed a hemizygous novel deletion, c.1867delC; p.(Gln623ArgfsTer26). CONCLUSIONS: Dental professionals can be the first-line specialists involved in the diagnosis of NHS due to its distinct dental findings. Our findings broaden the spectrum of genetic etiopathogenesis associated with NHS and aim to raise awareness among dental professionals.


Subject(s)
Cataract , Genetic Diseases, X-Linked , Intellectual Disability , Tooth, Supernumerary , Male , Female , Humans
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