ABSTRACT
OBJECTIVE:To observe the effect of Guizhi fuling pills on benign prostatic hyperplasia in mice.METHODS:Mice were injected intraperitoneally with testosterone propionate to induce benign prostatic hyperplasia model and then assigned to receive Guizhi fuling pills(high,medium and low doses)with Qianlie kang tablets as positive control.The mice were put to death at 24 h after the final medication with the wet weight of prostates measured and pathological examination conducted.RESULTS:In Guizhi fuling pills-treated mice,the indexes of prostate were significantly decreased compared with model group(P
ABSTRACT
Object To observe the effect of Guizhi Fuling Capsule (GFC) on prostatic hyperplasia in rats induced by testosterone propionate. Methods Seven days after the male rats were castrated, testosterone propionate (3 mg/kg) was sc injected in rats. Meanwhile, the rats were administered GFC (2.16, 1.08, 0.54 g/kg) once a day, and the treatment continued for 30 d. An hour after the final administration, the rats were put to death, and the weight and volume of prostates were measured. The construction of prostate cells was also observed under light microscope. Results In the GFC group, the weight and volume of prostate was significantly decreased compared with that in the model group (P
