ABSTRACT
In the face of a potential bird flu pandemic, Australian Federal Health Minister, Tony Abbott, has recently dismissed expert advice that the government should begin, or even publicly consider, authorising generic manufacturers to produce antivirals, such as Tamiflu and Relenza, under patent via non-voluntary licensing methods. This is despite the fact that the demand for antivirals in Australia, and throughout the world, cannot be met by manufacturers under the control of limited patent owners alone. This article proposes that Australian patent law, which allows for non-voluntary licensing when it comes to important public health issues that affect Australian citizens, is relevant in meeting the demand for increased antiviral treatments during a possible bird flu pandemic, domestically and abroad. It argues that the Australian Government must go beyond what is currently being done and investigate and pursue such options.
Subject(s)
Antiviral Agents/supply & distribution , Drugs, Generic/supply & distribution , Influenza, Human/drug therapy , Legislation, Drug , Patents as Topic/legislation & jurisprudence , Public Health/legislation & jurisprudence , Acetamides/supply & distribution , Animals , Australia , Birds , Guanidines/supply & distribution , Health Services Needs and Demand , Humans , Influenza A Virus, H5N1 Subtype/drug effects , Influenza in Birds , Oseltamivir , Pyrans/supply & distribution , Sialic Acids/supply & distribution , ZanamivirSubject(s)
Acetamides/supply & distribution , Antiviral Agents/supply & distribution , Influenza A Virus, H5N1 Subtype , Influenza, Human/prevention & control , Nurse Clinicians/organization & administration , Acetamides/economics , Acetamides/therapeutic use , Antiviral Agents/economics , Antiviral Agents/therapeutic use , Attitude to Health , Communicable Disease Control , Disease Outbreaks/prevention & control , Disease Outbreaks/statistics & numerical data , Drug Costs , Fear , Forecasting , Global Health , Humans , Influenza, Human/epidemiology , Influenza, Human/virology , Lobbying , Mass Media , Nurse's Role , Oseltamivir , Quarantine , United States/epidemiology , VaccinationSubject(s)
Acetamides , Antiviral Agents , Influenza A Virus, H5N1 Subtype , Influenza, Human/drug therapy , Acetamides/administration & dosage , Acetamides/chemical synthesis , Acetamides/economics , Acetamides/supply & distribution , Animals , Antiviral Agents/administration & dosage , Antiviral Agents/chemical synthesis , Antiviral Agents/economics , Antiviral Agents/supply & distribution , Chemistry, Pharmaceutical , Developing Countries , Drug Costs , Drug Industry , Drugs, Generic/chemical synthesis , Drugs, Generic/economics , Drugs, Generic/supply & distribution , Humans , Influenza A Virus, H5N1 Subtype/drug effects , Influenza, Human/prevention & control , Orthomyxoviridae Infections/drug therapy , Oseltamivir , Patents as Topic , Randomized Controlled Trials as TopicSubject(s)
Disaster Planning , Disease Outbreaks , Hospitals, University/organization & administration , Influenza A Virus, H5N1 Subtype , Influenza, Human/therapy , Intensive Care Units/organization & administration , Acetamides/supply & distribution , Antiviral Agents/supply & distribution , Boston , Ethics, Clinical , Health Care Rationing/ethics , Humans , Oseltamivir , Problem-Based Learning/methodsABSTRACT
The outbreak of H5N1 avian influenza in Asia has reignited concerns about an influenza pandemic. It is clear that influenza vaccine will be in short supply (or nonexistent) early in an influenza pandemic. Without vaccine, the role of antiviral agents, especially oseltamivir, in treatment and prophylaxis is of paramount importance. Unfortunately, the government cannot possibly stockpile enough oseltamivir to provide long-term prophylaxis or treatment for every healthcare worker in the United States. We think that hospitals should consider stockpiling oseltamivir, and we provide a strategy for doing so at a reasonable cost.