ABSTRACT
From the first reliable descriptions of acne in the early 19th century, dermatologists recognized it as a disease of the pilosebaceous follicle. Until the middle of the 20th century, they hypothesized that seborrhoea, follicular keratosis and microorganisms could be individually responsible for the acne lesions. Inflammation was only regarded as the final and inescapable step of the acne process. Although the importance of these factors has been reevaluated, recent works still regarded them as mandatory. In the 1970s, the onset of isotretinoin dramatically improved acne management. It also provided great opportunities for a better understanding of the pathogenic factors of acne. This study analyzes their genesis and development from the seminal contributions until recent advances.
Subject(s)
Acne Vulgaris/history , Dermatitis, Seborrheic/history , Gram-Positive Bacterial Infections/history , Inflammation/history , Propionibacterium acnes , Sebum , Skin Diseases, Bacterial/history , Acne Vulgaris/drug therapy , Acne Vulgaris/etiology , Acne Vulgaris/pathology , Animals , Anti-Bacterial Agents/therapeutic use , Dermatitis, Seborrheic/complications , Dermatologic Agents/therapeutic use , Diet/history , Gram-Positive Bacterial Infections/microbiology , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , History, 20th Century , History, 21st Century , Hormones/history , Humans , Inflammation/complications , Isotretinoin/therapeutic use , Skin Diseases, Bacterial/complications , Skin Diseases, Bacterial/microbiology , Vitamin A/therapeutic useABSTRACT
In his autobiography, Charles Bukowski (1920-1994) describes his severe acne conglobata, his experience with therapy, family conflicts and emotional tension. Despite the stigmatization by his acne scars, Bukowski became a philobatic writer and a true chronist of the American way of life in the second half of the 20th century, writing in a coarse and obscene language.
Subject(s)
Acne Vulgaris/history , History, 20th Century , Humans , Social Isolation , United StatesSubject(s)
Dermatology/history , Skin Diseases/history , Skin Diseases/pathology , Acne Vulgaris/history , Acne Vulgaris/pathology , History, 18th Century , History, 19th Century , History, 20th Century , Humans , Papilloma/history , Papilloma/pathology , Skin Neoplasms/history , Skin Neoplasms/pathologyABSTRACT
Apresenta informações sobre acne com ilustrações, mostra o que é, como é, como se dá sua formação, quais os tipos, o que causa, onde é encontrada, suas cosequências, anatomia e cuidados com a pele e lista de discussão, história em quadrinhos, e um desafio constituído por 3 conjuntos de 10 perguntas, com 4 alternativas cada. Completando as 3 fases, recebe o direito a participar da Discussão com o Dermatologista.
Subject(s)
Acne Keloid/history , Acne Keloid/diagnosis , Acne Keloid/prevention & control , Acne Vulgaris/history , Acne Vulgaris/diagnosis , Acne Vulgaris/prevention & control , Adolescent , HealthSubject(s)
Acne Vulgaris/history , Acne Vulgaris/etiology , Acne Vulgaris/therapy , History, 20th Century , Humans , PrognosisABSTRACT
Acne vulgaris is one of the commonest diseases known to humanity, affecting up to 98% of all adolescents. This review examines important aspects of its epidemiology, aetiology and management in Australia in the year 2000, in comparison with a symposium in the inaugural volume of the Australian Journal of Dermatology in 1951.
