ABSTRACT
Metabolite identification and metabolite profiling are of major importance in the pharmaceutical and clinical context. However, highly polar and ionic substances are rarely included as analytical tools are missing. In this study, we present a new method for the determination of urinary sulfates, sulfonates, phosphates and other anions of strong acids. The method comprises a CE separation using an acidic BGE (pHSubject(s)
Alkanesulfonates/urine
, Electrophoresis, Capillary/methods
, Phosphates/urine
, Spectrometry, Mass, Electrospray Ionization/methods
, Sulfates/urine
, Carbon Isotopes
, Formates/chemistry
, Humans
, Solid Phase Extraction
