ABSTRACT
The occurrence of Setaria digitata in a horse is reported for the first time in Malaysia. An 8-year-old Thoroughbred cross mare was referred to the University Veterinary Clinic with the primary complaint of corneal opacity and excessive eye discharge. After initial treatment with Terramycin eye ointment, corneal opacity cleared partially to reveal a moving thread-like cylindrical worm in the anterior chamber of the eye. The parasite was successfully removed surgically, and examination under the light microscope revealed that the isolated worm (lengthâ¯=â¯45â¯mm) was a 5th stage larva of S. digitata based on morphological criteria. Confirmation of the species of the worm was through molecular methods. The 12S rRNA gene was PCR-amplified, and the purified amplicon was directly sequenced. Phylogenetic analyses revealed that the isolated roundworm showed 100% sequence similarity with that of S. digitata in NCBI GenBank database (Accession no.: KY284626.1). This report is the first confirmed case of equine ocular setariasis by S. digitata in Malaysia. The current study provides evidence that S. digitata is an etiological agent of ocular infection and its presence in Malaysia.
Subject(s)
Eye Infections, Parasitic/veterinary , Horse Diseases/parasitology , Setaria Nematode/isolation & purification , Setariasis/diagnosis , Animals , Anterior Chamber/parasitology , Anterior Chamber/surgery , Anti-Bacterial Agents/therapeutic use , Base Sequence , DNA, Helminth/chemistry , DNA, Helminth/isolation & purification , Eye Infections, Parasitic/diagnosis , Eye Infections, Parasitic/parasitology , Eye Infections, Parasitic/surgery , Female , Horse Diseases/diagnosis , Horse Diseases/drug therapy , Horses , Larva/anatomy & histology , Larva/classification , Malaysia , Ointments , Oxytetracycline/therapeutic use , Phylogeny , Polymerase Chain Reaction/veterinary , RNA, Ribosomal/genetics , Setaria Nematode/anatomy & histology , Setaria Nematode/classification , Setaria Nematode/genetics , Setariasis/parasitology , Setariasis/surgeryABSTRACT
Live worm in anterior chamber is a rare finding. We hereby report a case of ocular Angiostrongylus cantonensis, which, to the best of our knowledge, is the third case report from India. A 70-year-old female presented with the complaints of watering and foreign body sensations in right eye since 2 months. On examination, a translucent worm of approximately 15 mm length was found freely moving in anterior chamber. Patient underwent surgical removal of live worm, which was identified as A. cantonensis. Educating people regarding importance of hygiene is important for prevention of worm infestation.
Subject(s)
Angiostrongylus cantonensis/isolation & purification , Anterior Chamber/parasitology , Eye Infections, Parasitic/diagnosis , Strongylida Infections/diagnosis , Aged , Animals , Anterior Chamber/surgery , Eye Infections, Parasitic/parasitology , Eye Infections, Parasitic/surgery , Female , Humans , Ophthalmologic Surgical Procedures/methods , Strongylida Infections/parasitology , Strongylida Infections/surgeryABSTRACT
We report a case of a 42-year-old female patient who presented to the ophthalmology outpatient department with painful red eye for 1 month. Slit-lamp microscopy showed a live worm in the anterior chamber of left eye. The worm was surgically removed under topical anaesthesia. It was sent to the microbiology department for further identification and was found to be adult female Loaloa.
Subject(s)
Anterior Chamber/parasitology , Eye Infections, Parasitic/diagnosis , Nematoda/isolation & purification , Adult , Animals , Anterior Chamber/surgery , Eye Infections, Parasitic/surgery , Female , Humans , Slit Lamp MicroscopySubject(s)
Acanthamoeba Keratitis/drug therapy , Acanthamoeba/isolation & purification , Antiprotozoal Agents/therapeutic use , Corneal Transplantation , Voriconazole/therapeutic use , Acanthamoeba Keratitis/surgery , Anterior Chamber/parasitology , Aqueous Humor/parasitology , Female , Humans , Male , Middle Aged , Postoperative Complications/prevention & controlSubject(s)
Anterior Chamber/parasitology , Eye Infections, Parasitic/parasitology , Spirurida Infections/parasitology , Spiruroidea/isolation & purification , Animals , Anterior Chamber/diagnostic imaging , Eye Infections, Parasitic/diagnosis , Humans , Male , Middle Aged , Slit Lamp Microscopy , Spirurida Infections/diagnosisSubject(s)
Anterior Chamber/parasitology , Disease Management , Eye Infections, Parasitic/surgery , Ophthalmologic Surgical Procedures/methods , Anterior Chamber/diagnostic imaging , Anterior Chamber/surgery , Eye Infections, Parasitic/diagnosis , Eye Infections, Parasitic/parasitology , Humans , MaleABSTRACT
BACKGROUND: Several parasites are known to affect the eyes, some of them even causing blindness. Data on helminths infecting the eye are scant and mostly limited to case reports from different countries. CASE: A 53 years old female presented with complaint of redness, foreign body sensation and diminution of vision in right eye since one month. OBSERVATIONS: On examination a live motile worm was found wriggling in the anterior chamber which was surgically removed. The microscopic findings were in favour of Dirofilaria. However, detailed histopathological examination and determination of species couldn't be done. CONCLUSION: The occurrence of parasite in eye is an uncommon event. Most of these parasites are found in subconjunctival or subretinal regions. Those in anterior chamber is a very rare event. Recently Dirofilaria is being recognised as an emerging zoonosis.
Subject(s)
Anterior Chamber/parasitology , Dirofilaria , Eye Infections, Parasitic/diagnosis , Animals , Anterior Chamber/diagnostic imaging , Anterior Chamber/surgery , Eye Infections, Parasitic/parasitology , Eye Infections, Parasitic/surgery , Female , Humans , Middle Aged , Ophthalmologic Surgical Procedures/methodsABSTRACT
This report describes a rare case of ophthalmic dirofilariasis in a 2-year-old boy with redness, irritation, pain and foreign body sensation in the right eye. Slit lamp examination demonstrated a thread-like whitish nematode in the anterior chamber of the right eye that twisted around itself. The nematode worm (35mm long and 150-200µm width) was removed surgically. The presence of the smooth cuticular surface without longitudinal ridges and the vulva showed that it could be a female Diroflaria immitis. PCR amplification was done to verify the Diroflaria species. PCR amplification and sequence analysis of mitochondrial 12S rDNA confirmed that recovered worm was D. immitis. Ocular dirofilariasis caused by D. immitis is very rare, but it must be considered in humans living in endemic areas.
Subject(s)
Dirofilaria immitis/isolation & purification , Dirofilariasis/parasitology , Eye Infections, Parasitic/parasitology , Animals , Anterior Chamber/parasitology , Child, Preschool , DNA, Ribosomal , Dirofilaria immitis/genetics , Dirofilariasis/diagnosis , Eye Infections, Parasitic/diagnosis , Humans , Iran , Male , Polymerase Chain Reaction , Slit Lamp MicroscopySubject(s)
Anterior Chamber/parasitology , Eye Infections, Parasitic/diagnosis , Loa/isolation & purification , Loiasis/diagnosis , Adult , Animals , Eye Infections, Parasitic/drug therapy , Eye Infections, Parasitic/parasitology , Female , Humans , Loa/ultrastructure , Loiasis/drug therapy , Loiasis/parasitology , NigeriaSubject(s)
Anterior Chamber/pathology , Cysticercosis/diagnosis , Eye Infections, Parasitic/diagnosis , Granuloma/diagnosis , Pupil Disorders/diagnosis , Uveitis, Anterior/diagnosis , Anterior Chamber/parasitology , Child , Combined Modality Therapy , Cysticercosis/parasitology , Cysticercosis/therapy , Diagnosis, Differential , Eye Infections, Parasitic/parasitology , Eye Infections, Parasitic/therapy , Female , Glucocorticoids/therapeutic use , Granuloma/parasitology , Granuloma/therapy , Humans , Ophthalmologic Surgical Procedures , Prednisolone/analogs & derivatives , Prednisolone/therapeutic use , Uveitis, Anterior/parasitology , Uveitis, Anterior/therapy , Visual AcuitySubject(s)
Anterior Chamber/parasitology , Brugia malayi/isolation & purification , Eye Infections, Parasitic/diagnosis , Filariasis/diagnosis , Adolescent , Animals , Cetirizine/therapeutic use , Combined Modality Therapy , Diethylcarbamazine/therapeutic use , Drug Therapy, Combination , Eye Infections, Parasitic/parasitology , Eye Infections, Parasitic/therapy , Female , Filariasis/parasitology , Filariasis/therapy , Glucocorticoids/therapeutic use , Humans , India , Leukocyte Count , Ophthalmologic Surgical ProceduresABSTRACT
We report a case of intraocular Linguatula in healthy young female who presented with a history of trivial trauma, dislocated lens, inflammation and secondary glaucoma. A mobile worm was seen in the anterior chamber. Pars plana lensectomy and vitrectomy was planned to remove both the cataractous lens and the parasite during which the worm disappeared from view but was later recovered from the cassette fluid. It was identified as the nymphal form of Linguatula serrata (tongue worm).
Subject(s)
Anterior Chamber/parasitology , Eye Infections, Parasitic/diagnosis , Lens Subluxation/etiology , Pentastomida , Adult , Animals , Eye Infections, Parasitic/complications , Eye Infections, Parasitic/parasitology , Female , Humans , Lens Subluxation/diagnosis , Lens Subluxation/surgery , Vitrectomy/methodsSubject(s)
Angiostrongylus cantonensis/isolation & purification , Anterior Chamber/parasitology , Eye Infections, Parasitic/diagnosis , Strongylida Infections/diagnosis , Animals , Eye Infections, Parasitic/surgery , Humans , Male , Middle Aged , Ophthalmologic Surgical Procedures , Strongylida Infections/surgeryABSTRACT
A 25-year femalepresented at the eye OPD with the complaint of some white thing in her right eye. She had visual acuity of 6/18 in the right eye and 6/6 in the left one. Slit lamp examination showed she had a live larva actively moving in the anterior chamber of the right eye. The patient was started on oral steroid, topical moxifloxacin with steroid, cyclopentolate and planned for surgery. Exploration of lerva was done by visco-expressive method. Histopathology showed if to be a cysticercus lerva. Her visual acurity was 6/6 in the affected eye after one month.
Subject(s)
Anterior Chamber/parasitology , Cysticercosis/diagnosis , Cysticercus/isolation & purification , Eye Infections, Parasitic/diagnosis , Adult , Animals , Cysticercosis/parasitology , Diagnosis, Differential , Eye Infections, Parasitic/parasitology , Female , Humans , LarvaSubject(s)
Anterior Chamber/parasitology , Eye Infections, Parasitic/diagnosis , Taenia solium/isolation & purification , Taeniasis/diagnosis , Adult , Animals , Diagnosis, Differential , Eye Infections, Parasitic/parasitology , Humans , Male , Middle Aged , Photomicrography , Taeniasis/parasitologyABSTRACT
Dirofilariasis is a parasitic infection of the carvivores that may present as a zoonotic infestation in humans. Systemic involvement in man is subcutaneous, pulmonary, or ocular. We report a rare occurrence of ocular dirofilariasis in a 25-year-old male patient who presented with pain and redness in the eye. A live, white, coiled, and highly motile worm was present in the anterior chamber. The worm, however, could not be detected in the anterior chamber, posterior segment, or the angle of the anterior chamber when the patient was taken to the operating room for surgical removal of the worm. The patient was made to lie prone till the worm reappeared in the anterior chamber and was removed by paracentesis. The worm was identified as Dirofilaria repens on the basis of microscopic and histopathological examination.
Subject(s)
Anterior Chamber/parasitology , Dirofilaria repens/isolation & purification , Dirofilariasis/diagnosis , Eye Infections, Parasitic/diagnosis , Adult , Animals , Anterior Chamber/pathology , Anterior Chamber/surgery , Diagnosis, Differential , Dirofilariasis/parasitology , Dirofilariasis/surgery , Eye Infections, Parasitic/parasitology , Eye Infections, Parasitic/surgery , Humans , Male , ParacentesisABSTRACT
PURPOSE: There are thousands of parasitic nematode species that have been identified. Many have been documented to invade the eye and periorbital tissues. Whether adult or larvae, alive or dead, they can result in a wide range of ocular and systemic manifestations. Classification of the nematode can be helpful in the treatment planning for these patients. CASE REPORT: A 60-year-old Hispanic male presented without complaints. During routine examination, the presence of peripheral anterior synechiae, posterior synechiae, and focal cataract were linked to an immobile, partly degenerated 2 to 3 mm long coiled nematode in the anterior chamber. CONCLUSION: Results from DNA analysis were most consistent with a member of the Trichostrongylus or Metastrongylus genera, or a new nematode species.
