ABSTRACT
The investigation has revealed an immunological character of the exudative reaction in postoperative period of patients with artificial crystalline lens. We noted a cellular immunodeficiency and an increase of immunoglobulins G and A in the lacrimal liquid. The administration of 5-FU (5-fluoroucile) and levamizol decreased the inflammation in the postoperative period.
Subject(s)
Adjuvants, Immunologic/therapeutic use , Aphakia, Postcataract/drug therapy , Aphakia, Postcataract/etiology , Fluorouracil/therapeutic use , Immunosuppressive Agents/therapeutic use , Lenses, Intraocular , Levamisole/therapeutic use , Postoperative Care/methods , Adolescent , Adult , Aged , Aged, 80 and over , Antibody Formation/drug effects , Aphakia, Postcataract/immunology , Humans , Immunity, Cellular/drug effects , Middle AgedABSTRACT
The immune system of the eye is closely connected with the immune system of homeostasis regulation of the body. The present research was aimed at the detection of the correlations between blood serum levels of autoantibodies to native and denatured DNA and the clinical course of the postoperative period after IOL implantation to cataract patients. Increased titers of both antibody types were found prognostically valuable. If only one parameter is increased (antibody titer to one DNA), the prognostic value of the test is reduced by 30%.