Subject(s)
Humans , Female , Adult , Recurrence , Carney Complex/diagnosis , Carney Complex/genetics , Ischemic Stroke/diagnosis , Heart Neoplasms/etiology , Aphasia, Broca/complications , Postoperative Complications/diagnostic imaging , Echocardiography/methods , Magnetic Resonance Spectroscopy/methods , Echocardiography, Transesophageal/methods , Continuity of Patient Care , Death, Sudden , Embolism/complications , Heart Neoplasms/surgeryABSTRACT
The superimposed clinical features of motor neuron disease (MND) and frontotemporal lobar degeneration (FTLD) comprise a rare neurological overlap syndrome that represents a diagnostic challenge to neurologists. Currently, FTLD-MND is considered a distinct entity and its clinicopathological basis has recently been reviewed. Our aim is to present a patient with MND and non-fluent rapidly progressive aphasia with clinical, imaging and histopathological correlation, as well as a brief review of the literature. We demonstrated the selective corticospinal tract (CST) and temporal lobe involvement using T1 spin-echo with an additional magnetization transfer contrast pulse on resonance (T1 SE/MTC) and FLAIR MR sequences in our patient, with further clinical and histopathological correlation. To the best of our knowledge, there is no description about the use of these particular MR sequences in the evaluation of FTLD-MND patients.
Subject(s)
Aphasia, Broca/complications , Motor Neuron Disease/complications , Aphasia, Broca/pathology , Humans , Magnetic Resonance Imaging/methods , Male , Middle Aged , Motor Neuron Disease/pathologyABSTRACT
This paper comments on Hagiwara's (1994b, this volume) proposals to account for the language deficits found in agrammatic aphasia, with special emphasis on Functional Categories (FCs). Some contemporary assumptions about FCs are reviewed focusing on their contentfulness, morphological features, and depiction as a heterogeneous set. This paper also discusses the view that the target of impairment in agrammatism constitutes a natural class. Treatment of FCs in their connection to chains and Lexical-Relatedness is discussed in terms of feature checking and morphological characteristics.
Subject(s)
Language Disorders/etiology , Aphasia, Broca/complications , Aphasia, Broca/physiopathology , Cross-Cultural Comparison , France , Germany , Humans , Italy , Japan , Language Disorders/diagnosis , Language Tests , Linguistics , Spain , SwedenABSTRACT
La afasia global sin hemiparesia es un síndrome neurológico reconocido a partir de 1982. El sustrato patológico de la presentación del síndrome ha sido relacionado con dos diferentes tipografías lesionales, demostradas por la tomografía axial computarizada cerebral; doble infarto que comprometen el área de BROCA y el área de WERNICKE, o infarto único perisilviano que respeta el territorio profundo capsular, en el hemisferio dominante. Siendo la encefalopatía embólica la causa más frecuente. Presentamos un nuevo caso de afasia global sin hemiparesia remarcando la localizacion perisilviana frontal como una de las localizaciones más frecuentes de lo que se puede esperar, asociado a signos de lesión frontal.