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1.
Rev. paul. med ; 107(3): 133-8, maio-jun. 1989. ilus
Article in Portuguese | LILACS | ID: lil-80136

ABSTRACT

Partindo-se da aparência radiológica altamente sugestiva de exposiçäo ao asbesto (caso 1) ou de uma história ocupacional positiva (casos 2 e 3), envestigamos a presença de fibras em tecido pulmonar em blocos de autópsia ou biópsia cirúrgica de três casos de carcinoma broncogênico, pelo método de digestäo de tecido pulmonar em hipoclorito de sódio, seguido da observaçäo do resíduo através da microscopia óptica por contraste de fase. Nos três casos, a pesquisa de fibras foi positiva. A relaçäo das neoplasias a exposiçäo ao asbesto é altamente provável, pelo fato de dois dos casos apresentaram fibrose pulmonar (casos 1 e 2) e, o terceiro caso, placas pleurais perietais típicas a toracotomia


Subject(s)
Aged , Humans , Male , Asbestos/isolation & purification , Lung Neoplasms/pathology , Carcinoma, Bronchogenic/pathology , Asbestos/analysis , Asbestos/adverse effects , Microscopy, Phase-Contrast , Lung Neoplasms/analysis , Carcinoma, Bronchogenic/analysis
2.
Rev Paul Med ; 107(3): 133-8, 1989.
Article in Portuguese | MEDLINE | ID: mdl-2699531

ABSTRACT

Based on the highly suspicious radiological findings of exposure to asbestos (case 1) or on a positive occupational history (cases 2 and 3), the authors looked for the presence of fibers in blocks of lung tissue removed in autopsy or surgical biopsies of three cases of bronchogenic carcinoma. The blocks were submitted to sodium hypochloride digestion followed by fiber identification in phase contrast light microscopy. The authors were able to demonstrate the presence of fibres in the three cases. The likelyhood of those carcinomas being caused by exposure to asbestos is very high, as two out of the three cases showed pulmonary fibrosis (cases 1 and 2) and the other case showed typical parietal pleural plaques at thoracotomy.


Subject(s)
Asbestos/isolation & purification , Carcinoma, Bronchogenic/analysis , Lung Neoplasms/analysis , Aged , Asbestos/adverse effects , Asbestosis/complications , Carcinoma, Bronchogenic/etiology , Carcinoma, Bronchogenic/pathology , Humans , Lung Neoplasms/etiology , Lung Neoplasms/pathology , Male , Microscopy, Phase-Contrast
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