ABSTRACT
Two cases of neonatal malaria are reported, both presenting with signs similar to neonatal sepsis. The first baby responded to oral Chloroquine (CQ) with fever and parasite clearance times of 48 h and 60 h respectively. The CQ treatment failed in the second baby and was subsequently treated successfully with oral Halofantrine hydrochloride. These cases indicate a need for routine blood film for malaria parasite as part of initial screening for neonatal sepsis.
Subject(s)
Malaria, Falciparum/congenital , Adult , Antimalarials/therapeutic use , Asphyxia Neonatorum/parasitology , Drug Resistance , Female , Humans , Infant , Infant, Newborn , Malaria, Falciparum/diagnosis , Malaria, Falciparum/drug therapy , Malaria, Falciparum/parasitology , Neonatal Screening , NigeriaABSTRACT
748 sera from lying-in women and newborns were tested for anti-toxoplasma antibody with the method of IHA. The positive rate was 13.1% in lying-in women, and 4.01% in newborns. The occurrence of spontaneous abortions in anti-toxoplasma antibody positive women was 36.7%, which was higher than that in normal lying-in women. The occurrence of Fetal Distress and Asphyxia Neonatorum were 33.3% and 40% respectively, both of which were higher that those in normal newborns.