ABSTRACT
La prevención cuaternaria ha sido definida comúnmente con el «primun non nocere» de los textos clásicos por muchos autores. El día a día de nuestras consultas en Atención Primaria están llenas de pacientes en las que nos preguntamos si el beneficio que pretendemos obtener con nuestra intervención superará el perjuicio que le ocasionamos al intervenir. Los pacientes pluripatológicos, polimedicados y complejos son frecuentes en nuestras consultas y cada vez se hace más complicado mover la balanza de nuestras actuaciones, diagnósticas o terapéuticas, hacia el lado del beneficio. A través de 2 casos clínicos frecuentes movemos a la reflexión de este problema. La prevención cuaternaria también debe estar presente en nuestra actividad diaria(AU)
Quaternary prevention has been commonly defined with the primum non nocere of classical texts by many authors. The daily life of our primary care consultations are full of patients in which we wondered if we try to obtain the benefit of our intervention will exceed the damage we cause him to intervene. Patients with multiple comorbidities, polypharmacy and complex are common in our consultations and it is becoming more difficult to move the balance of our actions, diagnostic or therapeutic benefit to the side. Through 2 cases often move to the reflection of this problem. Quaternary prevention must also be present in our daily activities(AU)
Subject(s)
Humans , Male , Female , Aged, 80 and over , Preventive Health Services/methods , Preventive Health Services/organization & administration , Preventive Health Services/standards , Primary Health Care/methods , Primary Health Care/organization & administration , Primary Health Care/standards , Acenocoumarol/therapeutic use , Primary Health Care , Quality of Life , Pharmacovigilance , Ventricular Fibrillation/prevention & control , Basal Ganglia Cerebrovascular Disease/prevention & controlABSTRACT
BACKGROUND: To define the cardiovascular risk factors for cerebral microbleeds and to investigate the relationship between microbleeds on the one hand, and the volume of age-related white matter hyperintensities (WMH) and atrophy on the other in an elderly population. METHODS: Four hundred and thirty-nine elderly subjects (age range: 72-85; mean: 77) suffering from vascular disease or at high risk for developing this condition were included in this study. For each subject the number and localization of the microbleeds was recorded. RESULTS: The prevalence of microbleeds in this study was 24%. We found age and a history of hypertension to be risk factors for microbleeds. After regional subdivision systolic blood pressure was found to be a risk factor for microbleeds located in the basal ganglia. A history of hypertension was more prevalent in patients with corticosubcortical and basal ganglia microbleeds. Magnetic resonance imaging risk factors associated with one or more microbleeds were total WMH volume, subcortical WMH volume, and periventricular WMH volume. Total WMH volume and periventricular WMH volume were risk factors for corticosubcortical microbleeds and basal ganglia microbleeds. CONCLUSION: A high prevalence of microbleeds was found in a population of patients suffering from vascular disease or at high risk for developing this condition. Age, hypertension and WMH were the most important risk factors for microbleeds, especially when located in the corticosubcortial junction or in the basal ganglia.
