ABSTRACT
Clinical infections by Bifidobacterium species rarely developed. We report two cases of bacteremic pneumonia caused by B. pseudocatenulatum and B. dentium, respectively, in patients vulnerable to aspiration. These cases suggested the potential for cause of serious pneumonia caused by Bifidobacterium species, in patients with high risk of aspiration.
Subject(s)
Bacteremia , Bifidobacteriales Infections , Bifidobacterium , Pneumonia , Bacteremia/diagnosis , Bacteremia/drug therapy , Bacteremia/microbiology , Bifidobacteriales Infections/diagnosis , Bifidobacteriales Infections/drug therapy , Bifidobacteriales Infections/microbiology , HumansABSTRACT
Alloscardovia omnicolens is a recently-reported microorganism with unknown pathogenic implications. It has been isolated in various clinical localizations but not in the endocervix. We isolated A. omnicolens in an endocervical sample from a 31-yr-old patient with preterm premature rupture of membranes (PPROM) in week 33+3 of pregnancy. The main risk of PPROM is prematurity and the possibility of developing infectious chorioamnionitis, which can be lethal for the mother and newborn. This is the first report of an association between A. omnicolens and PPROM, although its pathogenic role has not yet been elucidated.
Subject(s)
Actinobacteria , Bifidobacteriales Infections , Chorioamnionitis , Fetal Membranes, Premature Rupture , Actinobacteria/physiology , Adult , Anti-Bacterial Agents/therapeutic use , Bifidobacteriales Infections/complications , Bifidobacteriales Infections/drug therapy , Bifidobacteriales Infections/microbiology , Bifidobacteriales Infections/pathology , Cervix Uteri/microbiology , Chorioamnionitis/drug therapy , Chorioamnionitis/microbiology , Female , Fetal Membranes, Premature Rupture/etiology , Fetal Membranes, Premature Rupture/microbiology , Gestational Age , Humans , Pregnancy , Premature Birth , Treatment OutcomeABSTRACT
Although few cases of bacteremia or sepsis caused by probiotics have been reported, it is important to consider their pathogenic potential, especially in some categories of patients. We report a case of Bifidobacterium spp bacteremia in a child with heart disease, undergoing probiotic supplementation to prevent antibiotic-associated diarrhea.
Subject(s)
Bacteremia/microbiology , Bifidobacteriales Infections/microbiology , Bifidobacterium longum , Heart Failure/complications , Probiotics/adverse effects , Anti-Bacterial Agents/therapeutic use , Bacteremia/drug therapy , Bifidobacteriales Infections/drug therapy , Bifidobacterium longum/isolation & purification , Drug Administration Schedule , Extracorporeal Membrane Oxygenation , Female , Fever/microbiology , Heart Failure/microbiology , Heart Septal Defects, Atrial/complications , Humans , Infant , Mitral Valve Insufficiency/congenitalABSTRACT
Bifidobacterium species are anaerobic, Gram-positive bacilli that colonize the human intestinal tract and oral cavity. They are an infrequent cause of invasive human infection. We report a case of Bifidobacterium longum lumbar vertebrodiscitis in a 71 year old man who was subsequently diagnosed with liver cirrhosis and prostate cancer. The clinical outcome was good following antibiotic treatment with penicillin and clindamycin. The laboratory identification of Bifidobacterium species and risk factors for invasive infection are discussed.
Subject(s)
Bifidobacteriales Infections/diagnosis , Bifidobacteriales Infections/pathology , Bifidobacterium longum/isolation & purification , Discitis/diagnosis , Discitis/pathology , Fibrosis/complications , Prostatic Neoplasms/complications , Aged , Anti-Bacterial Agents/administration & dosage , Bifidobacteriales Infections/drug therapy , Discitis/drug therapy , Humans , Lumbosacral Region/pathology , Male , Treatment OutcomeABSTRACT
Bifidobacterium-a commensal of the human intestine is considered non-pathogenic and has been advocated as a probiotic due to its potential beneficial effects. However, there have been case reports implicating bifidobacteria as pathogenic agents in a variety of different infectious conditions. We discuss here one such case of a complicated urinary tract infection associated with Bifidobacterium spp.
Subject(s)
Bifidobacteriales Infections/diagnosis , Bifidobacterium/isolation & purification , Urinary Tract Infections/diagnosis , Aged , Anti-Bacterial Agents/therapeutic use , Bifidobacteriales Infections/drug therapy , Bifidobacteriales Infections/microbiology , Female , Humans , Tomography, X-Ray Computed , Urinary Tract Infections/drug therapy , Urinary Tract Infections/microbiologyABSTRACT
We report the one case of sepsis caused by Bifidobacterium breve administered as probiotic therapy. Probiotics can be a potential cause of an invasive disease and should be used with care in vulnerable patients.
