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2.
Emerg Infect Dis ; 18(1): 102-4, 2012 Jan.
Article in English | MEDLINE | ID: mdl-22257488

ABSTRACT

We report a case of type F botulism in a patient with bilateral but asymmetric neurologic deficits. Cranial nerve demyelination was found during autopsy. Bilateral, asymmetric clinical signs, although rare, do not rule out botulism. Demyelination of cranial nerves might be underrecognized during autopsy of botulism patients.


Subject(s)
Botulinum Antitoxin/therapeutic use , Botulinum Toxins/blood , Botulism/pathology , Cranial Nerves/pathology , Demyelinating Diseases/pathology , Aged , Botulism/blood , Botulism/rehabilitation , Botulism/therapy , Humans , Male
3.
Article in English | MEDLINE | ID: mdl-16557441

ABSTRACT

Botulism is a rare but potentially fatal disease caused by toxins produced by Clostridium botulinum. We report botulism in two adult females, one of them just tasting from "bad" asparagus and the other eating the full portion. Both patients survived after intermittent mechanical ventilation and trivalent antitoxin administration. The diagnosis was confirmed by detection of botulinum toxin. Acute onset of bilateral cranial neuropathies associated with symmetric descending weakness as well as some key features of the botulism syndrome including absence of fever, symmetric neurologic deficits, the patients remaining responsive and no sensory deficits, with the exception of blurred vision, led to the clinical diagnosis in the first presenting case which was then easily made in the second. Despite the fact that amount of toxin ingested, time-to-symptom development, and time-to-recovery markedly differed in the two patients, their maximal disease severity was similar.


Subject(s)
Botulinum Antitoxin/therapeutic use , Botulism/therapy , Vegetables , Adult , Botulism/pathology , Botulism/rehabilitation , Critical Care , Female , Food Preservation , Humans , Middle Aged , Respiration, Artificial
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