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1.
MMW Fortschr Med ; 154 Suppl 1: 1-7, 2012 Apr 05.
Article in German | MEDLINE | ID: mdl-23427362

ABSTRACT

UNLABELLED: This review offers readers new aspects for the guideline-compliant care of asthma patients. Here, attention is focused on illustrating the bottlenecks in the administration of good and practicable therapeutic care and listing these as "major challenges for GPs". The interdisciplinary team of authors - consisting of three hospital-based pulmonologists, one pulmonologist in private practice, one internist in general practice, one pharmacist and one health economist discussed aspects of asthma therapy relevant in clinical practice. RESULTS AND CONCLUSIONS: Practicable results for the reader included an asthma pentagram, a graphic depicting the links and interactions between diagnosis, symptom management, communication, application and costs. From this emerged a consensus on four recommendations that can help GPs improve their care of their patients: (1) Whenever possible, have a specialist verifythe diagnosis. (2) Practice inhalation techniques with the patient and check up on their technique at regular intervals. (3) Monitor and fine-tune the therapeutic goals set down together with the patient. (4) Clearly define the (patient's) responsibilities and who is organizing care (communication between GP-specialist-patient-pharmacist-family members).


Subject(s)
Adrenal Cortex Hormones/therapeutic use , Adrenergic beta-2 Receptor Agonists/therapeutic use , Anti-Asthmatic Agents/therapeutic use , Anti-Inflammatory Agents/therapeutic use , Asthma/drug therapy , Adrenal Cortex Hormones/adverse effects , Adrenal Cortex Hormones/economics , Adrenergic beta-2 Receptor Agonists/adverse effects , Adrenergic beta-2 Receptor Agonists/economics , Anti-Asthmatic Agents/adverse effects , Anti-Asthmatic Agents/economics , Anti-Inflammatory Agents/adverse effects , Anti-Inflammatory Agents/economics , Asthma/diagnosis , Asthma/economics , Asthma/epidemiology , Bronchial Hyperreactivity/diagnosis , Bronchial Hyperreactivity/drug therapy , Bronchial Hyperreactivity/economics , Bronchial Hyperreactivity/epidemiology , Cost-Benefit Analysis/economics , Cross-Sectional Studies , Delayed-Action Preparations/economics , Dose-Response Relationship, Drug , Drug Costs , Drug Therapy, Combination/economics , General Practice/economics , Germany , Humans , Lung Volume Measurements , National Health Programs/economics , Nebulizers and Vaporizers/economics , Patient Education as Topic/economics , Physician-Patient Relations , Risk Factors , Treatment Outcome
2.
Am J Respir Crit Care Med ; 158(6): 1730-8, 1998 Dec.
Article in English | MEDLINE | ID: mdl-9847260

ABSTRACT

The aim of this prospective study was to detect subjects in the general population with objective signs of chronic obstructive pulmonary disease (COPD) or asthma at an early stage. This was done by means of a two-stage protocol involving screening and a subsequent 2-yr monitoring of all subjects with positive results of screening. The study was done in 10 general practices located in the eastern part of the Netherlands. A random sample was taken from the general population aged 25 to 70 yr. All known COPD and asthma patients were excluded. A total of 1,749 subjects met the inclusion criteria: 1,155 subjects (66%) agreed to participate in the screening stage of the study. A total of 604 subjects (52.3%) showed symptoms or objective signs of COPD or asthma during the screening and were considered "positive." Of those with positive screening results, 384 subjects (64%) agreed to participate in the second, 2-yr monitoring stage of the study. The costs involved in detection were calculated for three different scenarios, as follows: (1) The detection of subjects with persistently decreased lung function or an increased level of bronchial hyperresponsiveness (BHR) during 6 mo of monitoring; (2) Scenario 1 plus the detection of subjects with a rapid decline in lung function with signs of BHR during 12 mo of monitoring; (3) Scenario 2 plus the detection of subjects with a moderate increase in the decline in lung function or signs of BHR during 24 mo of monitoring. The costs of lung function assessments, organization, transportation, and patient time were included. The costs were converted to United States dollars on the basis of purchasing power (1 United States dollar = 2.08 Netherlands guilders). During the second stage, 252 subjects were detected with objective signs of COPD or asthma at an early stage. Smoking status as a screening criterion was neither sensitive nor specific. Because there was no evidence of biased recruitment or selection during the program, the proportions of subjects found to have objective signs of COPD or asthma at an early stage could be extrapolated to the general population. Of the general population, 7.7% showed persistently reduced lung function or increased BHR. Another 12.5 % of the general population showed a rapid decline in lung function (> 80 ml/yr) in combination with signs of BHR, and a further 19.4% of the general population showed mild objective signs of COPD or asthma. The average costs per detected case varied from US$953 (Scenario 1) to US$469 (Scenario 3). In conclusion, detection of COPD or asthma at an early stage by means of a two-stage protocol was feasible at relatively little expense in comparison with other mass screening programs. Persistently decreased lung function or a rapid decline in lung function (Scenario 2) was observed in approximately 20% of the general adult population.


Subject(s)
Asthma/epidemiology , Lung Diseases, Obstructive/epidemiology , Adult , Aged , Asthma/economics , Bias , Bronchial Hyperreactivity/economics , Bronchial Hyperreactivity/epidemiology , Costs and Cost Analysis , Feasibility Studies , Female , Follow-Up Studies , Humans , Hypersensitivity/epidemiology , Lung/physiopathology , Lung Diseases, Obstructive/economics , Male , Mass Screening/economics , Mass Screening/organization & administration , Middle Aged , Netherlands/epidemiology , Population Surveillance , Prospective Studies , Respiratory Function Tests/economics , Sensitivity and Specificity , Smoking/epidemiology , Time Factors , Transportation of Patients/economics
3.
Rev Mal Respir ; 10(4): 313-23, 1993.
Article in French | MEDLINE | ID: mdl-8235022

ABSTRACT

This study describes the Quebec system of compensation for occupational asthma, assessing the functional and social outcome of claimants and estimating the efficiency and cost. Information was obtained on the clinical, functional and social outcome as well as the estimated costs for 134/211 subjects (participation rate of 64%), who received compensation between 1986 and 1988. At the time of assessment (2 years and more after the diagnosis), 93% of participants still demonstrated significant bronchial hyperresponsiveness and 84% required anti-asthma medication. None of the participants remained exposed to the offending agent: 67% were working for the same or another employer, 16% were retired, 8% were retraining for a new job and 8% were still unemployed. Quality of life was mildly affected, more so than for a control group of subjects. The mean interval between the time claims were addressed and the first medicolegal decision was 8.1 months. The mean total cost (including temporary and permanent disability indemnities, medical and technical costs) was $CAN 49,200 (minimum and maximum values of $2,100 and $330,900). We conclude that for subjects with occupational asthma in Quebec: 1) the mean interval for a medicolegal decision to be made is eight months: 2) a minority is still unemployed two to four years after being assessed; 3) the quality of life is more affected than in a control group; 4) the mean cost is close to $CAN 50,000.


Subject(s)
Asthma/rehabilitation , Bronchial Hyperreactivity/rehabilitation , Cost of Illness , Health Care Costs/statistics & numerical data , Occupational Diseases/rehabilitation , Workers' Compensation/organization & administration , Activities of Daily Living , Adult , Asthma/economics , Asthma/physiopathology , Asthma/psychology , Bronchial Hyperreactivity/economics , Bronchial Hyperreactivity/psychology , Costs and Cost Analysis , Decision Making, Organizational , Decision Trees , Disability Evaluation , Eligibility Determination/economics , Eligibility Determination/organization & administration , Female , Humans , Male , Middle Aged , Occupational Diseases/economics , Occupational Diseases/physiopathology , Occupational Diseases/psychology , Outcome Assessment, Health Care , Quality of Life , Quebec , Time Factors , Workers' Compensation/economics , Workers' Compensation/legislation & jurisprudence
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