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1.
Epidemiol Infect ; 146(1): 125-136, 2018 01.
Article in English | MEDLINE | ID: mdl-29173207

ABSTRACT

Knowledge, attitudes and practices (KAP) of the population regarding severe fever with thrombocytopenia syndrome (SFTS) in endemic areas of Lu'an in China were assessed before and after an intervention programme. The pre-intervention phase was conducted using a sample of 425 participants from the 12 selected villages with the highest rates of endemic SFTS infection. A predesigned interview questionnaire was used to assess KAP. Subsequently, an intervention programme was designed and applied in the selected villages. KAP was re-assessed for each population in the selected villages using the same interview questionnaire. Following 2 months of the programme, 339 participants had completed the re-assessed survey. The impact of the intervention programme was evaluated using suitable statistical methods. A significant increase in the KAP and total KAP scores was noted following the intervention programme, whereas the proportion of correct knowledge, the positive attitudes and the effective practices toward SFTS of respondents increased significantly. The intervention programme was effective in improving KAP level of SFTS in populations that were resident in endemic areas.


Subject(s)
Bunyaviridae Infections/psychology , Health Knowledge, Attitudes, Practice , Preventive Health Services/statistics & numerical data , Thrombocytopenia/psychology , Adult , Bunyaviridae Infections/virology , China , Female , Humans , Male , Middle Aged , Phlebovirus/physiology , Thrombocytopenia/virology , Young Adult
2.
Int J Neurosci ; 121(3): 165-9, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21126108

ABSTRACT

Toscana virus (TOSV) infection may often cause symptomatic meningitides and encephalitides. These usually subside in few days and their sequelae do not last for more than few weeks. We here report the case of a 49-year-old man who developed encephalitis after being bitten by phlebotomi in a region near southern Tuscany, where TOSV is endemic, and who developed postencephalitic seizures and subsequently, persistent personality alterations, characterized by sexually dissolute behavior and aggressiveness. One year after infection, the patient needs a combination of an SSRI antidepressant and a mood stabilizer/anticonvulsant to obtain less than optimal symptom improvement. This points to the need of establishing better preventive measures in Tuscany and nearby regions.


Subject(s)
Bunyaviridae Infections/psychology , Disruptive, Impulse Control, and Conduct Disorders/etiology , Encephalitis, Viral/psychology , Meningitis, Aseptic/psychology , Personality , Sandfly fever Naples virus/isolation & purification , Aggression , Antibodies, Viral/blood , Antibodies, Viral/cerebrospinal fluid , Anticonvulsants/therapeutic use , Antimanic Agents/therapeutic use , Brain/pathology , Bunyaviridae Infections/epidemiology , Bunyaviridae Infections/pathology , Bunyaviridae Infections/virology , Depressive Disorder/drug therapy , Depressive Disorder/etiology , Depressive Disorder/psychology , Depressive Disorder/virology , Disruptive, Impulse Control, and Conduct Disorders/drug therapy , Disruptive, Impulse Control, and Conduct Disorders/psychology , Disruptive, Impulse Control, and Conduct Disorders/virology , Encephalitis, Viral/pathology , Encephalitis, Viral/virology , Endemic Diseases , Epilepsies, Partial/drug therapy , Epilepsies, Partial/etiology , Epilepsies, Partial/virology , Gliosis/etiology , Gliosis/pathology , Humans , Italy/epidemiology , Magnetic Resonance Imaging , Male , Meningitis, Aseptic/pathology , Meningitis, Aseptic/virology , Middle Aged , Occupational Exposure , Prevalence , Sandfly fever Naples virus/immunology , Selective Serotonin Reuptake Inhibitors/therapeutic use , Sexual Behavior
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