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1.
Vopr Onkol ; 24(5): 3-6, 1978.
Article in Russian | MEDLINE | ID: mdl-208298

ABSTRACT

It is concluded that endolymphatic infusion of X-ray contrast substance in the presence of migrating tumor cells in lymphatic routes is inherent in a potential danger of tumor dissemination. Although getting of tumor cells in blood does not always result in metastases, nevertheless, a due account should be taken of the fact that lymphography is frequently performed in poor immunological resistance patients, preliminarily subjected to chemo- and radiotherapy. The decrease of immune resistance of the organism, in which the lymphatic system is of primary importance, is known to contribute per se to generalization of the tumor process. Another important conclusion is that the principal mass of tumor cells is ejected in the immediate period after endolymphatic injection of X-ray contrast substance. Thus, the cannulation of the thoracic duct during this period may prevent or reduce getting of massive amounts of tumor cells into the total blood flow.


Subject(s)
Lymphatic Metastasis , Lymphography/adverse effects , Animals , Carcinoma, Brown-Pearce/complications , Injections, Intralymphatic/adverse effects , Iodized Oil/adverse effects , Male , Neoplasms, Experimental/complications , Rabbits , Testicular Neoplasms/complications
2.
Vopr Onkol ; 21(4): 23-8, 1975.
Article in Russian | MEDLINE | ID: mdl-1198983

ABSTRACT

In rabbits transplanted Brown-Pearce carcinoma the content of nitrous compounds in tissues is changed in a different way: in the liver and kidneys -- nitrous compounds are accumulated, while in cardiac and skeletal muscles their concentration is diminished. It is found that tumor cells in mice with Ehrlich carcinoma accumulate radioactive aminoacid considerably faster than adjacent tissues not involved by neoplasma. A continuous glucose administration in tumor-bearing rabbits renders a marked nitrogen-saving effect by means of attenuation of catabolism of myoproteins, as a result of it the balance between the processes of synthesis and catabolism in host tissues is shifted toward synthesis.


Subject(s)
Carcinoma, Brown-Pearce/metabolism , Carcinoma, Ehrlich Tumor/metabolism , Hyperglycemia/metabolism , Nitrogen/metabolism , Amino Acids/metabolism , Animals , Carcinoma, Brown-Pearce/complications , Carcinoma, Ehrlich Tumor/complications , Creatine/metabolism , Creatinine/metabolism , Hyperglycemia/complications , Male , Proteins/metabolism , Rabbits , Urea/metabolism
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