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1.
J Vet Sci ; 25(3): e37, 2024 May.
Article in English | MEDLINE | ID: mdl-38834507

ABSTRACT

IMPORTANCE: The portal vein to aorta (PV/Ao) ratio is used to assess the clinical significance of extrahepatic portosystemic shunt (EHPSS). Previous studies using computed tomography (CT) were conducted in dogs but not in cats. OBJECTIVE: This study aimed to establish normal reference values for PV indices (PV/Ao ratio and PV diameter) in cats and determine the usefulness of these for predicting symptomatic EHPSS. METHODS: This study included 95 dogs and 114 cats that underwent abdominal CT. The canine normal (CN) group included dogs without EHPSS. The cats were classified into feline normal (FN, 88/114), feline asymptomatic (FA, 16/114), and feline symptomatic (FS, 10/114) groups. The PV and Ao diameters were measured in axial cross-sections. RESULTS: The group FN had a higher PV/Ao ratio than the group CN (p < 0.001). Within the feline groups, the PV indices were in the order FN > FA > FS (both p < 0.001). The mean PV diameter and PV/Ao ratio for group FN were 5.23 ± 0.77 mm and 1.46 ± 0.19, respectively. The cutoff values between groups FN and FS were 4.115 mm for PV diameter (sensitivity, 100%; specificity, 97.7%) and 1.170 for PV/Ao ratio (90%, 92.1%). The cutoff values between group FA and FS were 3.835 mm (90%, 93.8%) and 1.010 (70%, 100%), respectively. CONCLUSIONS AND RELEVANCE: The results demonstrated significant differences in PV indices between dogs and cats. In cats, the PV/Ao ratio demonstrated high diagnostic performance for symptomatic EHPSS. The PV diameter also performed well, in contrast to dogs.


Subject(s)
Cat Diseases , Portal Vein , Tomography, X-Ray Computed , Animals , Cats , Portal Vein/diagnostic imaging , Portal Vein/abnormalities , Cat Diseases/diagnostic imaging , Male , Female , Tomography, X-Ray Computed/veterinary , Dogs , Dog Diseases/diagnostic imaging , Reference Values , Aorta/diagnostic imaging
2.
Can Vet J ; 65(5): 457-461, 2024 May.
Article in English | MEDLINE | ID: mdl-38694738

ABSTRACT

A pregnant female domestic longhair cat ~8 mo of age was referred to the Western College of Veterinary Medicine (Saskatoon, Saskatchewan) for a diagnostic evaluation of severe anemia (PCV: 10.8%) after a 2-day period of lethargy. A CBC, serum biochemistry profile, FeLV/FIV testing, and abdominal radiographs were completed and did not determine a cause for the anemia. Abdominal ultrasonography identified 1 viable and 6 nonviable and fetuses, anechoic fluid in the uterus, and a mild volume of peritoneal effusion. A whole-blood transfusion and C-section with ovariohysterectomy were performed even though a definitive presurgical diagnosis for the anemia had not yet been established. Exploratory surgery revealed a left uterine horn torsion with a necrotic base, severe congestion, and 7 nonviable fetuses. Following surgery, the queen made a full clinical recovery. Key clinical message: Uterine torsion can be easily overlooked as a cause of severe anemia due to the relative infrequency of this condition in cats and the low sensitivity of ultrasonography to provide a definitive presurgical diagnosis. Client communication must emphasize the need for a prompt surgical intervention to establish the diagnosis and to save the cat, despite poor rates of neonatal survival. Once the animal is stabilized after surgery, further diagnostic tests and procedures are indicated if the cause of anemia has not yet been identified.


Reconnaître la torsion utérine comme un diagnostic différentiel chez les chattes gestantes souffrant d'anémie sévère afin de fournir des soins appropriés et opportuns en l'absence d'un diagnostic pré-chirurgical définitif. Une chatte domestique à poils longs, âgée d'environ 8 mois, a été référée au Western College of Veterinary Medicine (Saskatoon, Saskatchewan) pour une évaluation diagnostique d'anémie sévère (hématocrite : 10,8 %) après une période de léthargie de 2 jours. Une formule sanguine complète, un profil biochimique sérique, des tests FeLV/FIV et des radiographies abdominales ont été réalisés et n'ont pas permis de déterminer la cause de l'anémie. L'échographie abdominale a identifié 1 foetus viable et 6 non viables, du liquide anéchoïque dans l'utérus et un léger volume d'épanchement péritonéal. Une transfusion de sang total et une césarienne avec ovariohystérectomie ont été réalisées même si le diagnostic pré-chirurgical définitif de l'anémie n'avait pas encore été établi. La chirurgie exploratoire a révélé une torsion de la corne utérine gauche avec une base nécrotique, une congestion sévère et 7 foetus non viables. Après l'opération, la chatte s'est complètement rétablie cliniquement.Message clinique clé:La torsion utérine peut facilement être négligée comme cause d'anémie sévère en raison de la rareté relative de cette affection chez le chat et de la faible sensibilité de l'échographie pour fournir un diagnostic pré-chirurgical définitif. La communication avec le client doit souligner la nécessité d'une intervention chirurgicale rapide pour établir le diagnostic et sauver le chat, malgré de faibles taux de survie néonatale. Une fois l'animal stabilisé après la chirurgie, d'autres tests et procédures de diagnostic sont indiqués si la cause de l'anémie n'a pas encore été identifiée.(Traduit par Dr Serge Messier).


Subject(s)
Anemia , Cat Diseases , Torsion Abnormality , Uterine Diseases , Animals , Female , Cats , Pregnancy , Anemia/veterinary , Anemia/diagnosis , Cat Diseases/diagnosis , Cat Diseases/surgery , Cat Diseases/diagnostic imaging , Uterine Diseases/veterinary , Uterine Diseases/diagnosis , Uterine Diseases/surgery , Torsion Abnormality/veterinary , Torsion Abnormality/surgery , Torsion Abnormality/diagnosis , Diagnosis, Differential , Pregnancy Complications/veterinary , Pregnancy Complications/surgery , Pregnancy Complications/diagnosis , Hysterectomy/veterinary
3.
Article in German | MEDLINE | ID: mdl-38701807

ABSTRACT

A 3-month-old and a 4-year-old cat were presented in the clinic due to regurgitation. The kitten had displayed the symptoms since it had been fed solid foods and was smaller than the litter mates. The 4-year-old cat showed sudden-onset symptoms for 5 days prior to presentation and had a good general condition. Positive contrast thoracic radiographs of both cats in lateral recumbency showed an esophageal dilatation cranial to the heart base and raised a suspicion of foreign material with soft tissue density in this area. In the 4-year-old cat, findings of ventrodorsal thoracic radiographs were compatible with a dextroposition of the aorta and a slightly marked focal left curve of the trachea. The echocardiographic examination of the kitten pictured a right sided aorta, hence a vascular ring anomaly with a dextroposition from the aorta was suspected. Aberrant blood flow as it is seen in a persistent ductus arteriosus was not apparent in the echocardiography. As a result of the sudden development of the clinical signs in the older cat without displaying any former history of regurgitation, an esophagoscopy was performed to exclude an intraluminal esophageal cause for the stricture as well as to extract the foreign material. In this cat, computed tomography imaging also displayed an aberrant left subclavian artery. Both cats recovered well after surgical correction.The diagnosis of a ring anomaly in the kitten via echocardiography is a rare situation. As is the diagnosis of a high-grade esophageal stricture due to a vascular ring anomaly at the age of 4 without a former history of regurgitation.Recovery was excellent in the younger cat. There were no signs of regurgitation 6 months after surgery. The adult cat was in good general condition without clinical symptoms according to the owners when presented for stitch removal. Unfortunately, the adult cat was lost to follow up.


Subject(s)
Aorta, Thoracic , Cat Diseases , Esophageal Stenosis , Animals , Cats , Esophageal Stenosis/veterinary , Esophageal Stenosis/diagnostic imaging , Esophageal Stenosis/diagnosis , Cat Diseases/diagnosis , Cat Diseases/diagnostic imaging , Cat Diseases/surgery , Aorta, Thoracic/abnormalities , Aorta, Thoracic/diagnostic imaging , Aorta, Thoracic/surgery , Male
4.
J Vet Sci ; 25(2): e19, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38568821

ABSTRACT

A 2-year-old spayed female British Shorthair cat presented with an increased frequency and duration of cough since infant period. Based on radiographic, ultrasonographic, and computed tomography findings, peritoneopericardial diaphragmatic hernia was considered so that repair surgery was planned. During celiotomy, lax diaphragm was identified instead of defect. Transabdominal diaphragmatic plication was performed to resolve lax diaphragm and to prevent recurrence by overlapping relatively normal part of diaphragm. Diagnosed with diaphragmatic eventration postoperatively, the cat showed improvement in clinical signs and imaging results. Transabdominal diaphragmatic plication is a suitable treatment; the patient maintained normally during a 14-month follow-up period.


Subject(s)
Cat Diseases , Diaphragmatic Eventration , Hernia, Diaphragmatic , Female , Cats , Animals , Diaphragmatic Eventration/surgery , Diaphragmatic Eventration/veterinary , Diaphragm/surgery , Hernia, Diaphragmatic/veterinary , Cat Diseases/diagnostic imaging , Cat Diseases/surgery
5.
Vet Med Sci ; 10(3): e1425, 2024 05.
Article in English | MEDLINE | ID: mdl-38563757

ABSTRACT

BACKGROUND: Chronic sternal osteomyelitis is a rare condition in felines, with limited reported cases to date. OBJECTIVES: We report the case of a 2-year-old castrated male, domestic shorthair cat, weighing 4.68 kg, that presented with skin openings every 3-4 months, despite skin debridement and reconstruction. METHODS: A subcutaneous dead space larger than the skin defect was detected. Haematological analysis revealed elevated levels of inflammatory markers. Thoracic radiography revealed sternal deformation and suspected osteomyelitis. Computed tomography revealed a fistula extending from the third to the fourth sternebrae. RESULTS: Bone and soft tissue debridement and abscess flushing were performed along with long-term antibiotic therapy. The cat remained recurrence-free throughout an 18-month post-surgery follow-up period. CONCLUSION: To the best of our knowledge, this is the first report of chronic osteomyelitis occurring in a cat's sternebrae and represents the first successful case of its treatment. This case showcases the potential for improved treatment outcomes in similar cases. Understanding and successful treatment of such cases can pave the way for better management of feline osteomyelitis.


Subject(s)
Cat Diseases , Osteomyelitis , Male , Cats , Animals , Osteomyelitis/etiology , Osteomyelitis/surgery , Osteomyelitis/veterinary , Cat Diseases/diagnostic imaging , Cat Diseases/etiology
6.
BMC Vet Res ; 20(1): 154, 2024 Apr 24.
Article in English | MEDLINE | ID: mdl-38658930

ABSTRACT

BACKGROUND: In people, obesity is a risk factor for cardiovascular disease, associated with systemic hypertension, cardiac remodelling and systolic and diastolic dysfunction. Weight reduction can reverse myocardial remodelling and reduce risk of subsequent cardiovascular disease. In cats, far less is known regarding the effects of obesity and subsequent weight reduction on cardiovascular morphology and function. This prospective study aimed to assess cardiac morphology and function, heart rate variability, cardiac biomarkers and body composition before and after controlled weight reduction in cats with obesity. Body composition analysis (by dual energy x-ray absorptiometry, DEXA) and cardiovascular assessment (echocardiography, systemic arterial systolic blood pressure, electrocardiography, plasma cardiac biomarkers) were performed prior to weight management in twenty cats with obesity. These investigations were repeated in eleven cats that reached target weight. RESULTS: At baseline, systemic hypertension was not documented, but the majority of cats with obesity (15 out of 19) showed echocardiographic evidence of diastolic dysfunction. Eleven of 20 cats had increased maximal end-diastolic septal or left ventricular free wall thickness (≥ 6.0 mm) at baseline. Median (interquartile range) percentage of weight lost in the cats reaching target weight was 26% (17-29%), with a median reduction in body fat mass of 45% (26-64%). Both the end-diastolic left ventricular free wall (median magnitude of change -0.85 mm, IQR -0.05 mm to -1.55 mm, P = 0.019; median percentage reduction 14.0%) and end-diastolic interventricular septum (median magnitude of change -0.5 mm, IQR -0.2 mm to -1.225 mm, P = 0.047; median percentage reduction 7.9%) thickness decreased after weight reduction. Following weight reduction, pulsed wave tissue Doppler imaging of the left ventricular free wall was consistent with improved diastolic function in 4 out of 8 cats, however there was no significant difference in overall diastolic function class. Further, there was no change in heart rate variability or cardiac biomarkers with weight reduction. CONCLUSION: An increase in left ventricular wall thickness and diastolic dysfunction were common echocardiographic features in cats with obesity within our study and may be reversible with successful weight and fat mass loss. Further studies are required to clarify the clinical consequences of these findings.


Subject(s)
Body Composition , Cat Diseases , Echocardiography , Obesity , Weight Loss , Animals , Cats , Obesity/veterinary , Obesity/physiopathology , Male , Cat Diseases/physiopathology , Cat Diseases/diagnostic imaging , Female , Echocardiography/veterinary , Prospective Studies , Heart Rate , Blood Pressure , Heart , Biomarkers/blood , Electrocardiography/veterinary
7.
Vet Clin North Am Small Anim Pract ; 54(4): 707-720, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38503596

ABSTRACT

Idiopathic chylothorax is a challenging clinical condition historically associated with poor resolution rates following surgical intervention. Recent advances in imaging and surgical techniques have revolutionized the treatment of this disease process. Computed tomographic lymphangiography has facilitated improved surgical planning and postoperative assessment, while intraoperative use of near-infrared fluorescence imaging aids in highly accurate intraoperative thoracic duct identification. Utilizing these advancements, minimally invasive surgical techniques have been successfully developed and have been associated with considerable improvements in surgical outcomes.


Subject(s)
Cat Diseases , Chylothorax , Dog Diseases , Chylothorax/veterinary , Chylothorax/therapy , Chylothorax/surgery , Animals , Dog Diseases/surgery , Dog Diseases/therapy , Dog Diseases/diagnosis , Dogs , Cat Diseases/surgery , Cat Diseases/therapy , Cat Diseases/diagnosis , Cat Diseases/diagnostic imaging , Cats , Lymphography/veterinary
8.
J Vet Intern Med ; 38(3): 1563-1576, 2024.
Article in English | MEDLINE | ID: mdl-38438128

ABSTRACT

BACKGROUND: Microscopic nephrocalcinosis is a common pathological feature of chronic kidney disease (CKD) in cats. Detection of macroscopic nephrocalcinosis using ultrasonography and its implications remain unexplored. OBJECTIVES: Identify risk factors associated with ultrasound-diagnosed nephrocalcinosis and evaluate the influence of nephrocalcinosis on CKD progression. ANIMALS: Thirty-six euthyroid client-owned cats with CKD. METHODS: Prospective cohort study. Cats with CKD with and without ionized hypercalcemia were enrolled for renal ultrasonography. Cats were categorized according to the presence or absence of ultrasound-diagnosed nephrocalcinosis. Binary logistic regression was performed to identify nephrocalcinosis risk factors. The influence of nephrocalcinosis on CKD progression was assessed using linear mixed models. RESULTS: Ultrasound-diagnosed nephrocalcinosis was evident in 61% of CKD cats overall, with increased prevalence (81%) in those with hypercalcemia. At enrollment, higher blood ionized calcium concentration (odds ratio [OR], 1.27 per 0.1 mg/dL; P = .01), plasma phosphate concentration (OR, 1.16 per 0.1 mg/dL; P = .05), plasma creatinine concentration (OR, 1.29 per 0.1 mg/dL; P = .02) and alanine aminotransferase activity (OR, 2.08 per 10 U/L; P = .04) were independent nephrocalcinosis risk factors. The rate of change in log-transformed fibroblast growth factor-23 differed significantly between groups (P = .04). Cats with CKD and nephrocalcinosis had increasing plasma creatinine concentrations (.03 ± .01 mg/dL/month; P = .04) and phosphate concentrations (.06 ± .02 mg/dL/month; P < .001) and decreasing body weight (.02 ± .01 kg/month; P < .001) over time. CONCLUSIONS AND CLINICAL IMPORTANCE: Nephrocalcinosis is prevalent in cats with CKD, especially in those with hypercalcemia. This pathological feature appears to be associated with CKD progression in cats.


Subject(s)
Cat Diseases , Nephrocalcinosis , Renal Insufficiency, Chronic , Ultrasonography , Animals , Cats , Cat Diseases/diagnostic imaging , Nephrocalcinosis/veterinary , Nephrocalcinosis/diagnostic imaging , Nephrocalcinosis/complications , Renal Insufficiency, Chronic/veterinary , Renal Insufficiency, Chronic/complications , Risk Factors , Female , Ultrasonography/veterinary , Male , Prospective Studies , Hypercalcemia/veterinary , Calcium/blood , Cohort Studies , Creatinine/blood , Phosphates/blood
9.
Vet Radiol Ultrasound ; 65(3): 275-278, 2024 May.
Article in English | MEDLINE | ID: mdl-38459956

ABSTRACT

An 8-year-old cat was presented for an acute history of anorexia, marked abdominal pain, and hyperthermia. Ultrasonography showed a cecal perforation with focal steatitis and adjacent free gas bubbles, consistent with focal peritonitis. Surgery confirmed the imaging findings. An enterectomy was performed with the removal of the cecum and ileocolic valve, and anastomosis between the ileum and colon was performed. Histology revealed transmural enteritis and chronic severe pyogranulomatous peritonitis with intralesional plant fragments.


Subject(s)
Cat Diseases , Cecal Diseases , Intestinal Perforation , Ultrasonography , Animals , Cats , Cat Diseases/diagnostic imaging , Cat Diseases/surgery , Cat Diseases/diagnosis , Ultrasonography/veterinary , Cecal Diseases/veterinary , Cecal Diseases/diagnostic imaging , Cecal Diseases/surgery , Intestinal Perforation/veterinary , Intestinal Perforation/surgery , Intestinal Perforation/diagnostic imaging , Cecum/diagnostic imaging , Cecum/surgery , Cecum/injuries , Male , Peritonitis/veterinary , Peritonitis/diagnostic imaging , Peritonitis/etiology
10.
Article in German | MEDLINE | ID: mdl-38412958

ABSTRACT

A 12-year-old male neutered European Shorthair cat was presented for pruritus in the right ear region, bleeding from ear canal and a suspected polyp-like mass in its lumen.After the diagnostic imaging a biopsy of the mass was taken and submitted for histopathological evaluation. Histopathologic examination led to the diagnosis of low grade mast cell tumor. The subsequent staging examinations included ultrasonography of the liver and spleen as well as a complete blood count. Total ear canal ablation was performed on the same day, and the removed ear canal was again submitted for histopathologic evaluation of the surgical margins. The excision incision margins were free from infiltrating tumor cells. The cat was euthanised 14 months after the surgery. It is unknown whether the reasons for this were associated to metastatic spread of the initial mast cell tumor.A mast cell tumor in the ear canal is an unusual and rare finding, however it should be included in the list of differential diagnoses for ear canal tumors.


Subject(s)
Cat Diseases , Ear Neoplasms , Male , Animals , Cats , Ear Canal/diagnostic imaging , Ear Canal/surgery , Ear Canal/pathology , Mast Cells/pathology , Ear Neoplasms/diagnostic imaging , Ear Neoplasms/surgery , Ear Neoplasms/veterinary , Diagnosis, Differential , Biopsy/veterinary , Cat Diseases/diagnostic imaging , Cat Diseases/surgery
11.
Vet Ophthalmol ; 27(2): 191-196, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38413366

ABSTRACT

OBJECTIVE: The objective of the study was to describe the optical coherence tomographic features of a cat with acute corneal hydrops. ANIMAL STUDIED: A 4-year-old castrated male domestic shorthaired showing conjunctival redness, ocular discharge, and intermittent squinting of both eyes with asymmetrical disease onset. METHODS: Complete ophthalmic examination and optical coherence tomography were performed. RESULTS: On slit-lamp biomicroscopic examination, severe intrastromal fluid pockets with profound bullae were observed in the dorsomedial region in both eyes. A diagnosis of feline acute corneal hydrops was made in both eyes. Optical coherence tomography revealed profound stromal lamellar separation representing heterogeneous reflective areas, and fluid pockets and bullae of variable size were concomitant to Descemet's membrane detachment demonstrated by a well-defined homogeneous hyporeflective area. Upon reevaluation 30 days during healing process for both eyes, the thickened epithelia and the thinning pan-stromal areas were identified as homogeneously hyper-reflective epithelia and as heterogeneous hyper-reflectivity, respectively. A thickened posterior corneal surface was shown as heterogeneous with patchy hyper-reflectivity. Additionally, Descemet's membrane detachment in the initial presentation had two distinct forms suspicious of Descemet's membrane rupture in each eye: a break with rolled ends and a break with flat ends. CONCLUSION: To the author's knowledge, this study represents the first documentation of in vivo detection of Descemet's membrane detachment and presumed rupture in a cat experiencing acute corneal hydrops. These observations strongly indicate that Descemet's membrane detachment/rupture acts as a most likely risk factor in the onset of acute corneal hydrops in cats.


Subject(s)
Cat Diseases , Corneal Edema , Cats , Male , Animals , Descemet Membrane/diagnostic imaging , Tomography, Optical Coherence/veterinary , Tomography, Optical Coherence/methods , Blister/complications , Blister/veterinary , Cornea , Corneal Edema/diagnostic imaging , Corneal Edema/veterinary , Edema/complications , Edema/veterinary , Cat Diseases/diagnostic imaging
12.
Vet Med Sci ; 10(2): e1392, 2024 03.
Article in English | MEDLINE | ID: mdl-38389312

ABSTRACT

A 2-year-old neutered male Bengal cat presented with solid food dysphagia and chronic regurgitation for >5 months. There were no clinical abnormalities on haematological or radiographic examinations. Thoracic radiography revealed a soft tissue opacity mass adjacent to the diaphragm in the caudoventral thorax. Ultrasonography revealed a protruding liver lobe surrounded by a hyperechoic lining from the diaphragm towards the thorax, and a pleuroperitoneal hernia was diagnosed. An endoscopy was performed to examine the cause of regurgitation, and an oesophageal stricture was observed. Endoscopic balloon dilation of the oesophageal stricture was performed, and the regurgitation was resolved immediately. However, regurgitation relapsed 2 months later, and computed tomography was performed to ascertain the cause. Computed tomography revealed oesophageal mural thickening and true pleuroperitoneal hernia with partial liver lobe herniation. A second endoscopy with balloon dilation was performed to treat the relapsing oesophageal stricture, and the clinical signs resolved without the need for herniorrhaphy. Nevertheless, oesophageal stricture could occur due to gastroesophageal reflux related to a pleuroperitoneal hernia; however, a definite link could not be elucidated in this case. This report describes a case of oesophageal stricture and concurrent true pleuroperitoneal hernia in a cat.


Subject(s)
Cat Diseases , Esophageal Stenosis , Hernias, Diaphragmatic, Congenital , Male , Cats , Animals , Esophageal Stenosis/diagnostic imaging , Esophageal Stenosis/etiology , Esophageal Stenosis/veterinary , Hernias, Diaphragmatic, Congenital/veterinary , Tomography, X-Ray Computed , Thorax , Cat Diseases/diagnostic imaging , Cat Diseases/etiology
14.
J Feline Med Surg ; 26(2): 1098612X241228050, 2024 02.
Article in English | MEDLINE | ID: mdl-38415622

ABSTRACT

OBJECTIVES: The aim of the study was to describe clinical examination and thoracic CT (TCT) findings in cats after trauma, and to identify physical examination findings associated with both abnormalities on TCT and the need for therapeutic interventions. METHODS: A multicentre, retrospective, observational study was conducted. Cats admitted to the participating hospitals with a history of blunt trauma and that underwent TCT were eligible. Data were collected on signalment, history, physical examination, TCT findings and subsequent interventions. RESULTS: In total, 137 cats were included. Road traffic accidents (RTAs) were the most frequently reported cause of trauma (69%). Tachypnoea (32%), pale mucous membranes (22%) and dyspnoea (20%) were the most common abnormal findings on thoracic examination. The most frequently identified thoracic pathologies on TCT were atelectasis (34%), pulmonary contusions (33%), pneumothorax (29%) and pleural effusion (20%). Thoracocentesis was the most commonly performed intervention (12%), followed by chest drain placement (7%). A total of 45 (33%) cats had no physical examination abnormalities but did have abnormalities detected on TCT; six of these cats required interventions. Increasing numbers of thoracic abnormalities on clinical examination were associated with increasing likelihood of having abnormal findings on TCT (odds ratio [OR] 2.04, 95% confidence interval [CI] 1.21-3.44, P = 0.008) and of requiring an intervention (OR 1.82, 95% CI 1.32-2.51, P <0.001). CONCLUSIONS AND RELEVANCE: RTAs were the most common reported cause of blunt trauma. Atelectasis, pulmonary contusions and pneumothorax were the most common abnormalities identified on TCT, and thoracic drainage was the most utilised intervention. TCT may be useful in identifying cats with normal thoracic physical examination findings that have significant thoracic pathology, and a high number of abnormal findings on thoracic examination should raise suspicion for both minor and major thoracic pathology. The results of this study can be used to assist in selecting appropriate cases for TCT after blunt trauma.


Subject(s)
Cat Diseases , Contusions , Lung Injury , Pneumothorax , Thoracic Injuries , Wounds, Nonpenetrating , Cats , Animals , Pneumothorax/diagnostic imaging , Pneumothorax/etiology , Pneumothorax/veterinary , Retrospective Studies , Tomography, X-Ray Computed/veterinary , Thoracic Injuries/diagnostic imaging , Thoracic Injuries/veterinary , Lung Injury/veterinary , Wounds, Nonpenetrating/diagnostic imaging , Wounds, Nonpenetrating/veterinary , Contusions/veterinary , Physical Examination/veterinary , Hospitals , United Kingdom , Radiography, Thoracic/veterinary , Cat Diseases/diagnostic imaging
15.
J Vet Intern Med ; 38(3): 1553-1562, 2024.
Article in English | MEDLINE | ID: mdl-38348812

ABSTRACT

BACKGROUND: Identification of nephrocalcinosis in cats with chronic kidney disease (CKD) is of clinical interest but the ability of ultrasonography to detect nephrocalcinosis is uncertain. OBJECTIVES: To compare ultrasonography, micro-computed tomography (µCT) and histopathology for identification of nephrocalcinosis. ANIMALS: Twelve kidneys from 7 euthyroid client-owned cats with CKD. METHODS: Descriptive study. Renal ultrasonography was performed ante-mortem for nephrocalcinosis detection. Kidneys were grouped based on nephrocalcinosis: present, suspected, or absent. When cats died, necropsy was performed. Renal tissue was evaluated using µCT for macroscopic nephrocalcinosis, and nephrocalcinosis volume-to-kidney tissue ratio (macro-VN:KT) and sagittal nephrocalcinosis area-to-kidney tissue ratio (macro-AN:KT) were calculated. Each kidney subsequently was bisected longitudinally, formalin-fixed, and paraffin-embedded for microscopic nephrocalcinosis assessment using von Kossa and Alizarin red staining with AN:KT (VK-micro-AN:KT and AR-micro-AN:KT) quantified using ImageJ. Data are presented as median (range). Relationships between macroscopic and microscopic AN:KT were assessed using Spearman's correlation. RESULTS: Nephrocalcinosis by ultrasonography was considered to be absent in 3, suspected in 3, and present in 5 kidneys; 1 kidney had nephrolithiasis with nephrocalcinosis. The macro-VN:KT was 0.001%, 0.001%, and 0.019%, and the macro-AN:KT was 0.08%, 0.30%, and 1.47%, respectively. Histologically, VK-micro-AN:KT was 0.21%, 2.85%, and 4.56%, and AR-micro-AN:KT was 1.73%, 5.82%, and 8.90% for kidneys where ultrasonographic macro-nephrocalcinosis was absent, suspected, or present, respectively. A strong correlation was identified between macroscopic (macro-AN:KT) and microscopic (VK-micro-AN:KT) nephrocalcinosis (rs = 0.76; P = .01). CONCLUSIONS AND CLINICAL IMPORTANCE: Ultrasonographically diagnosed nephrocalcinosis correlates well with macroscopic and microscopic nephrocalcinosis at necropsy despite their separation in time.


Subject(s)
Cat Diseases , Nephrocalcinosis , Ultrasonography , X-Ray Microtomography , Animals , Cats , Nephrocalcinosis/veterinary , Nephrocalcinosis/diagnostic imaging , Nephrocalcinosis/pathology , Cat Diseases/diagnostic imaging , Cat Diseases/pathology , Ultrasonography/veterinary , X-Ray Microtomography/veterinary , Male , Female , Renal Insufficiency, Chronic/veterinary , Renal Insufficiency, Chronic/diagnostic imaging , Renal Insufficiency, Chronic/pathology , Kidney/pathology , Kidney/diagnostic imaging
16.
Vet Comp Oncol ; 22(2): 174-185, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38332673

ABSTRACT

Meningiomas are the most common feline primary brain tumours, and calvarial hyperostosis (CH) is frequently documented in association with this neoplastic entity. The clinical significance of and mechanisms driving the formation of CH in cats with meningiomas are poorly understood, although tumour invasion into the skull and tumour production of cytokines and enzymes have been implicated as causes of CH in humans. This retrospective study investigated relationships between signalment, MRI or CT imaging features, histopathologic tumour characteristics, alkaline phosphatase (ALP) isoenzyme concentrations, tumour expression of matrix metalloproteinases (MMP)-2, MMP-9, and interleukin-6 (IL-6), and progression free survival times (PFS) following surgical treatment in 27 cats with meningiomas with (n = 15) or without (n = 12) evidence of CH. No significant differences in breed, age, sex, body weight, tumour grade, tumour volume, peritumoral edema burden, ALP isoenzyme concentrations, tumour Ki-67 labelling indices or MMP-2 or MMP-9 expression and activity, or PFS were noted between cats with or without CH. There was a trend towards higher serum (p = .06) and intratumoral (p = .07) concentrations of IL-6 in cats with CH, but these comparisons were not statistically significant. Histologic evidence of tumour invasion into bone was observed in 5/12 (42%) with CH and in no (0/6) cats without CH, although this was not statistically significant (p = .07). Tumour invasion into bone and tumour production of IL-6 may contribute to the formation of meningioma associated CH in cats, although larger studies are required to further substantiate these findings and determine their clinical relevance.


Subject(s)
Cat Diseases , Hyperostosis , Magnetic Resonance Imaging , Meningeal Neoplasms , Meningioma , Tomography, X-Ray Computed , Animals , Meningioma/veterinary , Meningioma/diagnostic imaging , Meningioma/pathology , Cats , Cat Diseases/diagnostic imaging , Cat Diseases/pathology , Magnetic Resonance Imaging/veterinary , Female , Male , Hyperostosis/veterinary , Hyperostosis/diagnostic imaging , Hyperostosis/pathology , Retrospective Studies , Tomography, X-Ray Computed/veterinary , Meningeal Neoplasms/veterinary , Meningeal Neoplasms/diagnostic imaging , Meningeal Neoplasms/pathology , Meningeal Neoplasms/metabolism , Skull/diagnostic imaging , Skull/pathology , Matrix Metalloproteinase 2/metabolism , Matrix Metalloproteinase 9/metabolism , Interleukin-6/metabolism
17.
Vet Radiol Ultrasound ; 65(3): 246-249, 2024 May.
Article in English | MEDLINE | ID: mdl-38414109

ABSTRACT

A 13-year-old spayed female Persian cat presented with dyspnea and nasal discharge. Thoracic radiography revealed a dome-shaped soft-tissue opacity in the carina. Computed tomography confirmed a soft tissue-attenuating mass in the carina and the left and right proximal main bronchi that appeared to arise from the tracheal wall. Tracheoscopy revealed an intraluminal broad-based mass with multilobulated borders at the same location. Histopathological evaluation revealed a benign neoplastic process of the glandular epithelial lineage, which was considered an adenoma. Tracheal adenomas should be included in the differential diagnosis of tracheal masses.


Subject(s)
Adenoma , Cat Diseases , Tomography, X-Ray Computed , Tracheal Neoplasms , Animals , Cats , Female , Cat Diseases/diagnostic imaging , Cat Diseases/pathology , Tracheal Neoplasms/veterinary , Tracheal Neoplasms/diagnostic imaging , Adenoma/veterinary , Adenoma/diagnostic imaging , Adenoma/pathology , Tomography, X-Ray Computed/veterinary , Diagnosis, Differential , Trachea/diagnostic imaging , Trachea/pathology , Radiography, Thoracic/veterinary
18.
J Vet Cardiol ; 52: 14-18, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38342049

ABSTRACT

Feline arterial thromboembolism has been reported to be secondary to various feline cardiomyopathies; however, it has not been described in cats with transient myocardial thickening. A previously healthy, one-year-old, castrated male cat presented with acute paraparesis and congestive heart failure. Echocardiography revealed asymmetric left ventricular free wall thickening and left atrial enlargement. Antithrombotic treatment and cardiac medication resulted in reperfusion and mobility on day seven in one limb and on day 10 in the other. Different complications were managed successfully, including worsening acute kidney injury, inflammation, pleural effusion, and anemia. After three weeks, the cat was discharged and prescribed oral antithrombotic drugs (clopidogrel and rivaroxaban) and cardiac medication. Within five months, echocardiographic findings normalized, and medical treatment was gradually discontinued. To date, the cat remains healthy at 1735 days after the initial diagnosis and 1494 days after the last antithrombotic medication. To the best of our knowledge, this is the first case report on feline arterial thromboembolism combined with transient myocardial thickening, with favorable long-term survival.


Subject(s)
Cat Diseases , Thromboembolism , Cats , Animals , Male , Cat Diseases/drug therapy , Cat Diseases/pathology , Cat Diseases/diagnostic imaging , Cat Diseases/diagnosis , Thromboembolism/veterinary , Thromboembolism/drug therapy , Echocardiography/veterinary , Cardiomyopathies/veterinary , Cardiomyopathies/complications
19.
J Small Anim Pract ; 65(6): 387-393, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38234230

ABSTRACT

OBJECTIVES: To estimate the relative diagnostic sensitivity and specificity of oral clinical examination, full-mouth dental radiography, and cone-beam CT for the detection of tooth resorption in cats, and to estimate the prevalence of tooth resorption in unowned, unsocialised cats in Denmark. MATERIALS AND METHODS: Cadavers of 144 adult cats underwent an oral examination, full-mouth dental radiography, and cone-beam CT. Sensitivity and specificity of the three tests, along with the true prevalence, overall and stratified by sex and tooth location, were estimated using latent class methods. RESULTS: We found cone-beam CT to be the superior image modality, with a sensitivity of 99.5% and a specificity of 99.8%. Dental radiography had a sensitivity of 78.9% and a specificity of 100%, and oral clinical examination had a sensitivity of only 36.0% and specificity of 99.9%. We estimated the prevalence of tooth resorption among unowned unsocialised cats in Denmark to be 40% of adult individuals, and 6.1% of teeth. CLINICAL SIGNIFICANCE: When dealing with tooth resorption, cone-beam CT can help the operator to find and treat affected teeth that could otherwise go undiagnosed. The prevalence of tooth resorption among unowned, unsocialised cats in Denmark does not appear to differ from other populations of cats.


Subject(s)
Cat Diseases , Cone-Beam Computed Tomography , Radiography, Dental , Sensitivity and Specificity , Tooth Resorption , Animals , Tooth Resorption/veterinary , Tooth Resorption/diagnostic imaging , Tooth Resorption/epidemiology , Tooth Resorption/diagnosis , Cats , Denmark/epidemiology , Female , Male , Cone-Beam Computed Tomography/veterinary , Cat Diseases/diagnosis , Cat Diseases/epidemiology , Cat Diseases/diagnostic imaging , Radiography, Dental/veterinary , Prevalence , Cadaver
20.
Vet Comp Orthop Traumatol ; 37(1): 50-56, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37696299

ABSTRACT

OBJECTIVE: The aim of this study is to describe the use of String of Pearls (SOP) plates for the surgical management of feline pelvic fractures, including surgical technique, proposed indications, complications, and outcomes in a cohort of cats. STUDY DESIGN: This study is a single-center retrospective clinical case series. METHODS: Medical records (2015-2019) of cats presenting for pelvic fractures (n = 33) were reviewed. Type of fracture, preoperative and postoperative imaging, and complications were retrospectively retrieved. Owners were contacted via questionnaire for medium- and long-term follow-up. RESULTS: A total of 20 cats met the inclusion criteria. Minor intraoperative complications were encountered in three patients. One patient suffered a major intraoperative complication. Five major complications were encountered postoperatively. These included two greater trochanter osteotomy fixation implant removal and three SOP plate removal. Full function was recovered in all patients according to the owners' assessment. CLINICAL SIGNIFICANCE: The use of SOP plates in feline pelvic fractures appears to yield a consistently good outcome with a very low incidence of canal narrowing and screw loosening. SOP plates are easy to contour and to apply along the entire pelvic length.


Subject(s)
Cat Diseases , Fractures, Bone , Pelvic Bones , Cats , Animals , Retrospective Studies , Fractures, Bone/surgery , Fractures, Bone/veterinary , Pelvic Bones/diagnostic imaging , Pelvic Bones/surgery , Fracture Fixation, Internal/veterinary , Pelvis , Bone Plates/veterinary , Cat Diseases/diagnostic imaging , Cat Diseases/surgery
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