Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace.

A 56-year-old Korean man visited to emergency room due to paroxysmal flaccid paralysis in his lower extremities. There was no family or personal history of periodic paralysis. His initial potassium levels were 1.8 mmol/L. The patient had been taking Salicornia herbacea for the treatment of diabetes and hypertension. Results of a thyroid function test were as follows: T3 = 130.40 ng/dL, TSH = 0.06 mIU/L, and free T4 = 1.73 ng/dL. A thyroid scan exhibited a decreased uptake (0.6%). His symptoms clearly improved and serum potassium levels increased to 4.4 mmol/L by intravenous infusion of only 40 mmol of potassium chloride. Eight months after the discontinuation of only Salicornia herbacea, the patient's thyroid function tests were normalized. Large amounts of iodine can induce hypokalemic thyrotoxic paralysis and it may be necessary to inquire about the ingestion of iatrogenic iodine compounds, such as Salicornia herbacea.

Skin prick test reactivity to common aeroallergens among allergic rhinitis patients in Iran

Background: Allergic rhinitis is the most common allergic disease with negative impacts on patients’ quality of life. The prevalence and pattern of sensitisation vary between different countries and populations. Identification of the most prevalent aeroallergens in each area has avery important role in diagnosis and treatment of allergic rhinitis. Iran is a fairly large country with different geo-climatic conditions and there are no data aboutthe most prevalent aeroallergen in Mashhad City, which is the second largest city in Iran, with asemiarid climate. The aim of this study was to evaluate the prevalence of positive skin test to various common aeroallergens among allergic rhinitis patients in the city of Mashhad. Materials and Methods: Skin prick tests were performed with 27 common regional aeroallergens including grass, weed, tree, mite and mould in 311 patients with allergic rhinitis. Results: The overall rate of sensitisation to any allergen was 81 %. 76 % of patients were poly-sensitised and weed and grass were the most prevalent allergens (77 % and 62 % respectively). Salsola Kali and mould were the most and the least prevalent individual allergens (72.5 % and 6.5 % respectively). Mean total IgE in patients with positive skin prick test was significantly higher than in patients without any positive skin prick test (308 vs 128 IU/mL,P = 0.016). 97 % of atopic patients were sensitised to Salsola kali and or Fraxinus americana. Conclusions: Our work showed the importance of weeds, especially the Amaranthaceae and Chenopodiaceae families. Diagnosis of pollen allergy can be simplified by using a combination of a few common aeroallergens (AU)

No disponible

Associations among pollen sensitizations from different botanical species in patients living in the northern area of Madrid.

OBJECTIVE: To determinate the existence of associations among sensitizations to antigens produced by pollen grains of different botanical species as assessed by skin prick tests in patients with respiratory disorders. METHODS: Six hundred twenty nine consecutive patients living in the northern area of Madrid who underwent clinical evaluation because of rhinoconjunctivitis, and/or asthma were studied. All patients were tested with a skin prick test using a battery of inhalants including pollens, dust mites, molds and danders. The exploratory multivariate technique of Multiple Correspondence Analysis was used to compare the homogeneity of sensitizations between groups. Of the 629 patients, 459 (73.0%) had positive skin prick tests to pollen and were selected as the study group. RESULTS: The most prevalent pollen sensitization was to Gramineae pollen (83.7%) followed by Oleaceae sensitisation (75.8%). Multiple Correspondence Analysis revealed the existence of an association among pollen sensitizations, showing that they clustered two groups: sensitizations to Gramineae, Oleaceae, Cupressaceae, Chenopodiaceae, Plantaginaceae (group I), and sensitizations to Betulaceae, Platanaceae, Compositae (group II). Sensitization to Parietaria was not included in any of the sensitization groups and showed an independent behaviour. CONCLUSION: Pollen sensitizations in our area cluster into two association groups which have not previously been reported.

The seasonal variation in allergic rhinitis and its correlation with outdoor allergens in Kuwait.

BACKGROUND: Allergic rhinitis (AR) is the most common allergic problem in Kuwait. Most of the patients who have either AR or asthma are referred to the Al-Rashed Allergy Center. OBJECTIVE: To determine if there is a seasonal variation in AR in Kuwait and to correlate it with the daily pollen count. METHODS: Information about the new patients referred to the center over a 5-year study period (1996-2000) was extracted from the center's records. The daily pollen count in Kuwait city was obtained from the Air Biology Laboratory. RESULTS: There was a significant seasonal variation with a bimodal increase in the number of patients with AR referred to the center. The main peak in the number of patients occurred in September-October, and there was a smaller peak in April-May. The mean number +/- SD of new patients per month over the 5-year period varied from 87 +/- 32 for December to 367 +/- 104 for September. Similarly, the average daily pollen count varied from 3.7 +/- 1.0 pollens per mm3 in January to 124 +/- 92 in October. There was high correlation between the number of new AR patients and the average total pollen count (Pearson correlation, r=0.77, p<0.001), as well as with Chenopodiaceae and Amaranthaceae (weed) pollens (r=0.75, p<0.001), while there was no correlation between the number of new patients and either tree or grass pollens. CONCLUSION: Seasonal AR occurs during two periods in Kuwait, i.e. September-October and April-May, with September-October being the main season. The rise in AR during late summer in Kuwait is mainly associated with the pollination of Chenopodiaceae species.

Polinosis en la región de Bahía Blanca / Pollinosis in the region of Bahía Blanca

El presente trabajo pretende mostrar una descripción actualizada de las polinosis en nuestra zona. Se efectuó el relevamiento profesional de las plantas conocidas y/o sospechadas como alergógenas en la región de Bahía Blanca. Se estudió el polen absoluto en el aire durante 3 años. Se realizó un calendario floral de 30 especies, controlando sus inflorescencias durante el mismo lapso. Fueron preparados extractos con los pólenes antecitadas y posteriormente testificados en cien pacientes afectados por polinosis. Ochenta y seis enfermos mostraron pruebas positivas a gramíneas compuestas y quenopodiáceas; sólo catorce fueron positivos a gramíneas únicamente. Los síntomas por estos últimos pólenes fueron particularmente frecuentes e intensos en el mes de noviembre, correspondiendose con la floración de aquella familia. Sin embargo, a pesar de las reacciones positivas - marcadas y frecuentes - para quenopodiáceas, las consultas durante el verano disminuyeron ostensiblemente. No fue demostrada una correlación clínica significativa entre la floración de las compuestas y la signosintomatología del grupo estudiado. Consideramos imprescindible el acabado conocimiento de la flora alergógena y su calendario floral para el diagnóstico y tratamiento de la polinosis (AU)

Polinosis en la región de Bahía Blanca / Pollinosis in the region of Bahía Blanca

El presente trabajo pretende mostrar una descripción actualizada de las polinosis en nuestra zona. Se efectuó el relevamiento profesional de las plantas conocidas y/o sospechadas como alergógenas en la región de Bahía Blanca. Se estudió el polen absoluto en el aire durante 3 años. Se realizó un calendario floral de 30 especies, controlando sus inflorescencias durante el mismo lapso. Fueron preparados extractos con los pólenes antecitadas y posteriormente testificados en cien pacientes afectados por polinosis. Ochenta y seis enfermos mostraron pruebas positivas a gramíneas compuestas y quenopodiáceas; sólo catorce fueron positivos a gramíneas únicamente. Los síntomas por estos últimos pólenes fueron particularmente frecuentes e intensos en el mes de noviembre, correspondiendose con la floración de aquella familia. Sin embargo, a pesar de las reacciones positivas - marcadas y frecuentes - para quenopodiáceas, las consultas durante el verano disminuyeron ostensiblemente. No fue demostrada una correlación clínica significativa entre la floración de las compuestas y la signosintomatología del grupo estudiado. Consideramos imprescindible el acabado conocimiento de la flora alergógena y su calendario floral para el diagnóstico y tratamiento de la polinosis