1.
Int J Oral Maxillofac Surg
; 17(4): 219-23, 1988 Aug.
Article
in English
| MEDLINE
| ID: mdl-3139789
ABSTRACT
The 3 cases of cherubism reported affected the mandible. They were all studied by means of histo-enzymological and ultrastructural methods. This study demonstrated 3 stages in the morphological evolution of the disease, corroborated by clinical data. The 1st stage was characterized by an osteolytic granuloma with round, fusiform and giant-cells and a high level of activity of acid phosphatase. The 2nd stage showed repair with proliferation of highly active fibroblasts (increase in activity of leucine aminopeptidase). The 3rd stage exhibited an osteogenesis with high activity of alkaline phosphatase and ATPase. The pathogenesis of this rare osteodysplasia is discussed.
Subject(s)
Cherubism/pathology , Mandible/pathology , Adolescent , Adult , Cherubism/enzymology , Fibroblasts/enzymology , Fibroblasts/pathology , Granuloma/pathology , Humans , Male , Mandible/enzymology , Mandible/ultrastructure , Microscopy, Electron , Osteoblasts/ultrastructure , Osteolysis/pathology , Oxidoreductases/metabolism
2.
Arch Anat Cytol Pathol
; 35(2): 69-75, 1987.
Article
in French
| MEDLINE
| ID: mdl-3632062
3.
Dtsch Zahnarztl Z
; 28(11): 1089-94, 1973 Nov.
Article
in German
| MEDLINE
| ID: mdl-4520089
Subject(s)
Cherubism/diagnosis , Fibrous Dysplasia of Bone/diagnosis , Jaw Diseases/diagnosis , Alkaline Phosphatase/blood , Blood Sedimentation , Calcium/blood , Cherubism/blood , Cherubism/diagnostic imaging , Cherubism/enzymology , Cherubism/etiology , Child, Preschool , Diagnosis, Differential , Granuloma, Giant Cell/complications , Humans , Male , Phosphates/blood , Radiography
4.
J Pathol
; 101(4): Pix, 1970 Aug.
Article
in English
| MEDLINE
| ID: mdl-5504736
