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1.
J Cardiothorac Surg ; 19(1): 318, 2024 Jun 04.
Article in English | MEDLINE | ID: mdl-38835049

ABSTRACT

Thymoma is a rare malignancy with usual location in the antero-superior mediastinum. Ectopic cervical thymoma (ECT) is an extremely rare tumor that originates from ectopic tissue, and is caused by the aberrant migration of the embryonic thymus. Our patient was a 56-year-old man who had a nodular lesion in the neck for several years. Computed tomography and Enhanced magnetic resonance imaging were performed. He underwent surgery, and a histological examination resulted in a diagnosis of type AB thymoma.


Subject(s)
Choristoma , Magnetic Resonance Imaging , Thymoma , Thymus Neoplasms , Tomography, X-Ray Computed , Humans , Male , Middle Aged , Thymoma/surgery , Thymoma/diagnosis , Thymoma/diagnostic imaging , Thymoma/pathology , Thymus Neoplasms/surgery , Thymus Neoplasms/diagnosis , Thymus Neoplasms/diagnostic imaging , Thymus Neoplasms/pathology , Choristoma/surgery , Choristoma/diagnosis , Choristoma/pathology , Choristoma/diagnostic imaging , Neck/diagnostic imaging , Head and Neck Neoplasms/surgery , Head and Neck Neoplasms/diagnosis , Head and Neck Neoplasms/pathology , Head and Neck Neoplasms/diagnostic imaging
2.
BMJ Case Rep ; 17(5)2024 May 28.
Article in English | MEDLINE | ID: mdl-38806400

ABSTRACT

Transverse testicular ectopia (TTE) is an infrequent ectopic testis where both testes descend via the same inguinal canal, located in the same hemiscrotum, and augments the risk of developing testicular tumours. Type II TTE is accompanied by persistent Müllerian duct syndrome, where the Müllerian structures persist for various reasons. Here, we present a case of an adult in his early 30s, who presented with a right testicular swelling and was diagnosed as type II TTE and testicular mixed germ cell tumour after surgery. We could find only 13 similar cases of TTE and testicular tumours in the literature. Our case highlights the importance of clinical acumen with detailed history, meticulous clinical examination, radiological investigations and a detailed pathological examination while dealing with such sporadic presentations.


Subject(s)
Disorder of Sex Development, 46,XY , Neoplasms, Germ Cell and Embryonal , Testicular Neoplasms , Testis , Humans , Male , Testicular Neoplasms/surgery , Testicular Neoplasms/diagnosis , Testicular Neoplasms/complications , Testicular Neoplasms/diagnostic imaging , Neoplasms, Germ Cell and Embryonal/surgery , Neoplasms, Germ Cell and Embryonal/complications , Neoplasms, Germ Cell and Embryonal/diagnosis , Neoplasms, Germ Cell and Embryonal/diagnostic imaging , Adult , Testis/abnormalities , Testis/surgery , Testis/diagnostic imaging , Disorder of Sex Development, 46,XY/diagnosis , Disorder of Sex Development, 46,XY/surgery , Disorder of Sex Development, 46,XY/complications , Choristoma/surgery , Choristoma/diagnosis , Choristoma/complications , Choristoma/diagnostic imaging
3.
Pediatr Surg Int ; 40(1): 141, 2024 May 29.
Article in English | MEDLINE | ID: mdl-38811418

ABSTRACT

OBJECTIVE: Heterotopic pancreas, an uncommon condition in children, can present with diagnostic and treatment challenges. This study aimed to evaluate the clinical features and treatment options for this disorder in pediatric patients. METHODS: We conducted a retrospective analysis, including patients diagnosed with heterotopic pancreas at four tertiary hospitals between January 2000 and June 2022. Patients were categorized into symptomatic and asymptomatic groups based on clinical presentation. Clinical parameters, including age at surgery, lesion size and site, surgical or endoscopic approach, pathological findings, and outcome, were statistically analyzed. RESULTS: The study included 88 patients with heterotopic pancreas. Among them, 22 were symptomatic, and 41 were aged one year or younger. The heterotopic pancreas was commonly located in Meckel's diverticulum (46.59%), jejunum (20.45%), umbilicus (10.23%),ileum (7.95%), and stomach (6.82%). Sixty-six patients had concomitant diseases. Thirty-three patients had heterotopic pancreas located in the Meckel's diverticulum, with 80.49% of cases accompanied by gastric mucosa heterotopia (GMH). Patients without accompanying GMH had a higher prevalence of heterotopic pancreas-related symptoms (75%). Treatment modalities included removal of the lesions by open surgery, laparoscopic or laparoscopic assisted surgery, or endoscopic surgery based on patient's age, the lesion site and size, and coexisting diseases. CONCLUSIONS: Only one-fourth of the patients with heterotopic pancreas presented with symptoms. Those located in the Meckel's diverticulum have commonly accompanying GMH. Open surgical, laparoscopic surgical or endoscopic resection of the heterotopic pancreas is recommended due to potential complications. Future prospective multicenter studies are warranted to establish rational treatment options.


Subject(s)
Choristoma , Pancreas , Humans , Retrospective Studies , Choristoma/surgery , Choristoma/diagnosis , Male , Female , Pancreas/surgery , Child , Child, Preschool , Infant , Adolescent , Meckel Diverticulum/surgery , Meckel Diverticulum/diagnosis
4.
BMJ Case Rep ; 17(4)2024 Apr 22.
Article in English | MEDLINE | ID: mdl-38649245

ABSTRACT

A man in his mid-40s presented to the colorectal surgery clinic with complaints of chronic perianal pain for over 20 years. He had episodes of urinary incontinence associated with pain. There were no other symptoms to suspect bowel pathology. On examination, he was found to have a tender mass in the retro-rectal plane without any evidence of rectal mucosal irregularity. He underwent an MRI of the pelvis, which showed a well-defined T2 hyperintense partly cystic lesion in the presacral region abutting the mesorectal fascia and a normal prostate gland. With a suspicion of a tailgut cyst or a duplication cyst, he underwent an excision of the presacral mass. Intraoperatively, there was a 2 × 2 cm well-defined firm, cystic lesion anterior to the fifth sacral vertebra and coccyx. The lesion was adherent to the mesorectum and was excised. On histopathology, there were features of muscular stroma and bilayered glandular epithelium with clear cytoplasm conclusive of a benign ectopic prostate.


Subject(s)
Choristoma , Magnetic Resonance Imaging , Prostate , Humans , Male , Prostate/pathology , Prostate/diagnostic imaging , Prostate/surgery , Choristoma/surgery , Choristoma/diagnosis , Choristoma/diagnostic imaging , Diagnosis, Differential , Adult
5.
J Cardiothorac Surg ; 19(1): 184, 2024 Apr 06.
Article in English | MEDLINE | ID: mdl-38582893

ABSTRACT

The occurrence of ectopic pancreas in the mediastinum is rare. Herein, we report a 22-year-old female who presented with right shoulder pain, dysphagia, fever and headaches. Chest computer tomography revealed a mass in the posterior mediastinum with accompanying signs of acute mediastinitis. Needle biopsy and fine-needle aspiration revealed ectopic gastral tissue and ectopic pancreas tissue, respectively. Surgical resection was attempted due to recurring acute pancreatitis episodes. However, due to chronic-inflammatory adhesions of the mass to the tracheal wall, en-bloc resection was not possible without major tracheal resection. Since then, recurring pancreatitis episodes have been treated conservatively with antibiotics. We report this case due to its differing clinical and radiological findings in comparison to previous case reports, none of which pertained a case of ectopic pancreas tissue in the posterior mediastinum with recurring acute pancreatitis and mediastinitis.


Subject(s)
Choristoma , Mediastinitis , Pancreatitis , Female , Humans , Young Adult , Acute Disease , Choristoma/surgery , Choristoma/diagnosis , Mediastinitis/diagnosis , Mediastinitis/surgery , Mediastinitis/complications , Mediastinum/diagnostic imaging , Mediastinum/pathology , Pancreas/pathology , Pancreatitis/complications , Pancreatitis/diagnosis
6.
BMC Ophthalmol ; 24(1): 140, 2024 Mar 28.
Article in English | MEDLINE | ID: mdl-38549111

ABSTRACT

BACKGROUND: An ocular osseous choristoma is a growth of mature, compact bone in the ocular or periocular soft tissue, and it is the rarest form of ocular choristoma, accounting for only 1.7% of all epibulbar choristomas. CASE PRESENTATION: Herein we present the case of a 20-month-old girl who was referred to the oculoplasty clinic with a progressively growing mass in the left lateral canthus. It had been present since birth without ocular involvement. Upon examination the mass was firm with a smooth surface, measured 9 × 6 × 3 mm, and exhibited no episcleral attachment or ocular involvement. An excisional biopsy was performed, and the histopathological findings were consistent with osseous choristoma of the left lateral canthus. CONCLUSIONS: This report highlights the importance of considering osseous choristoma in the differential diagnosis of eyelid lesions, particularly those that have been present since birth. It also emphasizes the need for further studies investigating associations between osseous choristomas and ocular canthi.


Subject(s)
Choristoma , Eye Diseases , Lacrimal Apparatus , Female , Humans , Infant , Choristoma/diagnosis , Choristoma/surgery , Choristoma/pathology , Lacrimal Apparatus/pathology , Eye Diseases/surgery , Eyelids/pathology , Bone and Bones/pathology
7.
Am Surg ; 90(7): 1919-1921, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38520268

ABSTRACT

Ectopic parathyroid adenomas are an uncommon etiology of primary hyperparathyroidism. We present a case of a patient admitted to the hospital with severe hypercalcemia and elevated parathyroid hormone levels, in whom imaging revealed two distinct parathyroid masses in the prevertebral space, representing a rare and atypical location for parathyroid tissue. This case highlights the importance of considering ectopic parathyroid adenomas as a potential cause of hyperparathyroidism and discusses the diagnostic challenges and management strategies associated with such cases.


Subject(s)
Adenoma , Parathyroid Neoplasms , Humans , Parathyroid Neoplasms/surgery , Parathyroid Neoplasms/complications , Parathyroid Neoplasms/diagnosis , Adenoma/surgery , Adenoma/complications , Adenoma/pathology , Choristoma/complications , Choristoma/surgery , Choristoma/diagnosis , Female , Hyperparathyroidism, Primary/etiology , Hyperparathyroidism, Primary/surgery , Hyperparathyroidism, Primary/diagnosis , Hyperparathyroidism, Primary/complications , Middle Aged , Male , Parathyroid Glands/diagnostic imaging , Parathyroid Glands/pathology , Parathyroidectomy , Hypercalcemia/etiology
8.
Arch Gynecol Obstet ; 309(6): 2911-2912, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38459998

ABSTRACT

A 29-year-old primigravida at 31 weeks of gestation was referred for intrathoracic kidney (ITK). Ultrasound revealed left kidney intrathoracic placement with an anteriorly positioned ectopic adrenal gland. Magnetic resonance imaging confirmed diaphragmatic interruption and colon herniation. A female neonate, delivered at 37 weeks, underwent successful thoracoscopic repair for a left Bochdalek hernia. Despite compression of the left lung, notably optimistic lung-to-head ratio (LHR) values were observed, correlating with favorable outcomes. This case underscores the rare occurrence of ITK, its association with Bochdalek hernia, and the importance of comprehensive prenatal evaluations.


Subject(s)
Adrenal Glands , Hernias, Diaphragmatic, Congenital , Kidney , Ultrasonography, Prenatal , Humans , Female , Hernias, Diaphragmatic, Congenital/diagnostic imaging , Hernias, Diaphragmatic, Congenital/surgery , Adult , Pregnancy , Kidney/diagnostic imaging , Kidney/abnormalities , Adrenal Glands/diagnostic imaging , Infant, Newborn , Magnetic Resonance Imaging , Choristoma/diagnostic imaging , Choristoma/surgery , Choristoma/diagnosis
9.
Eur J Ophthalmol ; 34(3): NP101-NP104, 2024 May.
Article in English | MEDLINE | ID: mdl-38380886

ABSTRACT

PURPOSE: To report an atypical presentation of an epibulbar simple cartilaginous choristoma with a unique pigmented multicystic component. CASE DESCRIPTION: A 69-year-old African American female presented for evaluation of a right nasal epibulbar lesion that had progressed over the prior year. Slit-lamp evaluation revealed an immobile, mildly pigmented multicystic lesion measuring 6.0 × 4.5 mm that involved the nasal bulbar conjunctiva and the plica semilunaris. The lesion appeared benign, without feeder vessels or features of epithelial dysplasia. Given its recent growth and the patient's cosmetic concerns, the lesion was excised with ocular surface reconstruction. Histopathological evaluation disclosed a well-circumscribed nodule of well-differentiated cartilage in the substantia propria, consistent with a simple cartilaginous choristoma. The overlying conjunctival stroma contained multiple cysts lined by focally pigment epithelium. The patient recovered well from surgery, with satisfactory cosmetic results. CONCLUSIONS: Our case of epibulbar simple cartilaginous choristoma includes a prominent superficial component of pigmented epithelial cysts, which has not been previously reported in the literature. This augments our knowledge on the spectrum of presentations of cartilaginous choristomas and underscores the importance of histopathological evaluation for definitive diagnosis.


Subject(s)
Choristoma , Humans , Choristoma/diagnosis , Choristoma/pathology , Choristoma/surgery , Female , Aged , Conjunctival Diseases/diagnosis , Conjunctival Diseases/surgery , Cartilage/pathology , Cysts/diagnosis , Cysts/surgery , Conjunctiva/pathology , Ophthalmologic Surgical Procedures , Pigment Epithelium of Eye/pathology
10.
BMC Pediatr ; 24(1): 97, 2024 Feb 03.
Article in English | MEDLINE | ID: mdl-38310216

ABSTRACT

Heterotopic brain tissue is rare and has not been reported. Our center made the first report. 4 years and 2 months old Girl presented with a cystic mass in the right adrenal gland 2 weeks after right upper abdominal pain. The operation was successful, and the diagnosis was confirmed by postoperative pathology. 6 months after the procedure, the incision healed well without recurrence. This case report has a detailed diagnosis and treatment process and satisfactory examination results. It can provide a reference for diagnosing and treating clinical HBT and reduce the risk of misdiagnosis and mistreatment.


Subject(s)
Adrenal Glands , Choristoma , Child , Female , Humans , Infant , Adrenal Glands/diagnostic imaging , Adrenal Glands/surgery , Choristoma/surgery , Choristoma/pathology , Abdominal Pain/etiology , Head/pathology
11.
Acta Med Okayama ; 78(1): 89-93, 2024 Feb.
Article in English | MEDLINE | ID: mdl-38419320

ABSTRACT

We report our experience with the diagnosis and treatment of an ectopic breast cancer arising within an axillary lymph node. The patient was a 65-year-old woman diagnosed breast cancer and axillary lymph node metastasis. We performed a partial mastectomy and axillary lymph node dissection. Postoperative pathology revealed no malignant lesions in the breast; however, a nodule in one of axillary lymph nodes had mixed benign and malignant components, leading to a diagnosis of invasive ductal carcinoma derived from ectopic mammary tissue. This case represents a very rare form of breast cancer, and the malignancy was difficult to distinguish from metastasis.


Subject(s)
Breast Neoplasms , Choristoma , Female , Humans , Aged , Breast Neoplasms/pathology , Mastectomy , Lymph Nodes/pathology , Breast , Lymph Node Excision , Choristoma/surgery , Choristoma/pathology
12.
Can Vet J ; 65(1): 29-32, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38164377

ABSTRACT

A 4.6-year-old spayed female German shepherd dog was admitted to a specialty hospital emergency service upon referral for suspected gastrointestinal foreign body obstruction. Free abdominal fluid was collected, and results of cytologic evaluation were consistent with a septic abdomen. An abdominal barium study revealed free gas and intraperitoneal barium, along with an obstructive gas pattern within the small bowel. Ultrasonography revealed a full-thickness jejunal perforation. On exploratory laparotomy, the perforation was noted to be located mid-jejunum with no associated mass or foreign material. A resection and anastomosis were completed. Histopathologic evaluation of the affected jejunal tissue showed aberrant gastric glandular epithelium consistent with a gastric choristoma, or heterotopic gastric tissue. Key clinical message: Clinicians should consider gastric glandular choristoma as a differential diagnosis in cases of seemingly idiopathic small intestinal perforation with no known cause (i.e., foreign body penetration, neoplasia, NSAID use), and histopathologic evaluation should always be done to obtain a definitive diagnosis.


Perforation jéjunale et abdomen septique résultant d'un choristome chez un chien. Une chienne berger allemand stérilisée âgée de 4,6 ans a été admise dans le service d'urgence d'un hôpital spécialisé après avoir été référée pour une suspicion d'obstruction gastro-intestinale par un corps étranger. Du liquide abdominal libre a été prélevé et les résultats de l'évaluation cytologique étaient compatibles avec un abdomen septique. Un examen abdominal à l'aide de baryum a révélé du gaz libre et du baryum intrapéritonéal, ainsi qu'un patron de gaz obstructif dans l'intestin grêle. L'échographie a révélé une perforation sur toute l'épaisseur jéjunale. Lors d'une laparotomie exploratoire, il a été constaté que la perforation était située au milieu du jéjunum, sans masse ni corps étranger associé. Une résection et une anastomose ont été réalisées. L'évaluation histopathologique du tissu jéjunal affecté a montré un épithélium glandulaire gastrique aberrant compatible avec un choristome gastrique ou un tissu gastrique hétérotopique.Message clinique clé :Les cliniciens doivent considérer le choristome glandulaire gastrique comme diagnostic différentiel dans les cas de perforation de l'intestin grêle apparemment idiopathique sans cause connue (i.e. pénétration d'un corps étranger, néoplasie, utilisation d'AINS), et une évaluation histopathologique doit toujours être effectuée pour obtenir un diagnostic définitif.(Traduit par Dr Serge Messier).


Subject(s)
Choristoma , Dog Diseases , Foreign Bodies , Intestinal Perforation , Stomach Diseases , Animals , Dogs , Female , Intestinal Perforation/diagnosis , Intestinal Perforation/surgery , Intestinal Perforation/veterinary , Choristoma/complications , Choristoma/diagnosis , Choristoma/surgery , Choristoma/veterinary , Barium , Abdomen , Stomach Diseases/veterinary , Foreign Bodies/veterinary , Dog Diseases/diagnosis , Dog Diseases/surgery
13.
14.
Surgery ; 175(3): 794-798, 2024 Mar.
Article in English | MEDLINE | ID: mdl-37985315

ABSTRACT

BACKGROUND: The purpose of our study was to determine the frequency and management of intrathyroidal parathyroid glands in patients with primary hyperparathyroidism and evaluate whether intrathyroidal parathyroid glands were more often superior or inferior glands. METHODS: A retrospective review of the prospective parathyroid database was completed to determine the number of patients with primary hyperparathyroidism and an intrathyroidal parathyroid gland. Demographic data, laboratory and localization studies, operative management, pathology, and outcome were determined for patients with an intrathyroidal parathyroid gland and were compared with patients with an extrathyroidal parathyroid gland. RESULTS: From 1990-2023, 808 patients were operated on for primary hyperparathyroidism; 17 (2%) patients had an intrathyroidal parathyroid gland, an adenoma in 15 (88.2%), and a hyperplastic gland in 2 (11.8%). The mean age was 53 years; 16 (94%) patients were female. Mean calcium and parathyroid hormone was 12 mg/dL and 150 pg/mL, and there were no differences from the extrathyroidal parathyroid group. Ultrasound and Sestamibi imaging were valuable in identifying an intrathyroidal parathyroid gland in 10 of 13 patients and 13 of 17 patients, respectively. Local excision was performed in 9 (53%) patients and lobectomy in 8 (47%) patients. Intraoperative parathyroid hormone was measured and predictive of cure in 12 patients. The location of intrathyroidal parathyroid glands was determined in 15 patients and was inferior in 11 (73%). All patients were cured. No patient developed recurrent disease after a median 54-month follow-up. CONCLUSION: Intrathyroidal parathyroid glands are the cause of primary hyperparathyroidism in 2% of patients and are most often inferior glands. Local excision was accomplished in 53% of our patients.


Subject(s)
Choristoma , Hyperparathyroidism, Primary , Humans , Female , Middle Aged , Male , Parathyroid Glands/diagnostic imaging , Parathyroid Glands/surgery , Parathyroid Glands/pathology , Hyperparathyroidism, Primary/diagnosis , Hyperparathyroidism, Primary/etiology , Hyperparathyroidism, Primary/surgery , Prospective Studies , Choristoma/complications , Choristoma/diagnosis , Choristoma/surgery , Parathyroid Hormone , Technetium Tc 99m Sestamibi , Parathyroidectomy
16.
Medicine (Baltimore) ; 102(50): e36672, 2023 Dec 15.
Article in English | MEDLINE | ID: mdl-38115260

ABSTRACT

RATIONALE: A choristoma is a rare and benign neoplasm characterized by the presence of normal tissue in an anomalous anatomical location. In contrast, choristoma tend to occur in other body regions rather than within the spinal canal. Before our findings, only 4 cases of intraspinal choristoma had been recorded. Because its composition is complex and very rare, routine examinations, such as magnetic resonance imaging, are difficult to diagnose, and the possibility of its occurrence is often missed in clinical diagnosis. If there is no specificity in its components, such as in this case, even pathological examinations can only confirm the diagnosis as choristoma after eliminating other possibilities. Therefore, in clinical practice, when encountering patients with intraspinal tumors, it is essential to consider the possibility of choristoma. In this case, the choristoma lack of specific constituent composition sets it apart from previously reported intraspinal choristoma, significantly raising the diagnostic challenge, which offers valuable insights for clinical diagnosis. PATIENT CONCERNS: A female patient aged 48 years was admitted to our medical center due to experiencing persistent lower back pain accompanied by radiating pain in both legs for 5 months. Based on the findings from the neurological physical examination and magnetic resonance imaging, the patient was diagnosed with an intradural space-occupying lesion located at the level of the first lumbar vertebral body. We performed an enhanced magnetic resonance neurography examination to further determine the positional relationship between the occupation and nerves in preparation for surgery. Postoperative pathological biopsy showed that the mass was an intraspinal choristoma. DIAGNOSIS: Intradural extramedullary spinal choristoma. INTERVENTION: Occupied lesion is removed surgically. OUTCOMES: After surgery, all symptoms were significantly relieved, and when the patient was discharged, all symptoms disappeared completely. There was no sign of recurrence after 1 year of follow-up. LESSONS: Intraspinal choristomas are not specific and need to be diagnosed by pathologic examination. Early detection of and intervention for intraspinal tumors can mitigate nerve dysfunction.


Subject(s)
Choristoma , Low Back Pain , Spinal Neoplasms , Female , Humans , Choristoma/diagnosis , Choristoma/surgery , Magnetic Resonance Imaging , Spinal Canal , Spinal Neoplasms/diagnostic imaging , Spinal Neoplasms/surgery , Treatment Outcome , Middle Aged
17.
Ann Ital Chir ; 94: 400-403, 2023.
Article in English | MEDLINE | ID: mdl-37794801

ABSTRACT

Crossed Testicular Ectopia (CTE) or transverse testicular ectopia is an anecdotic urogenital anomaly in which both testes are located on the same side, generally associated with a patent processus vaginalis (PPV). The condition can be detected by ultrasound. Nevertheless, the diagnosis is often missed preoperatively and CTE is recognized intraoperatively. Controversy exists regarding management and the role of diagnostic laparoscopy. The surgical technique depends on the anatomy of vas, vessels and testis found on surgical exploration. Diagnostic laparoscopy can be useful to rule out a vanishing testis and detect Müllerian remnants. We present the case of 8-months infant with no palpable testis on the right side and no signs of inguinal hernia, reporting the management and reviewing the scarce existing literature in this regarding. KEY WORDS: Crossed Testicular Ectopia, Laparoscopy, Ectopia, Testis, Transverse Testicular Ectopia, Urogenital Abnormalities.


Subject(s)
Choristoma , Cryptorchidism , Hernia, Inguinal , Laparoscopy , Male , Infant , Humans , Testis/diagnostic imaging , Testis/surgery , Testis/abnormalities , Cryptorchidism/complications , Cryptorchidism/diagnosis , Cryptorchidism/surgery , Choristoma/diagnostic imaging , Choristoma/surgery , Ultrasonography , Hernia, Inguinal/diagnostic imaging , Hernia, Inguinal/surgery , Hernia, Inguinal/complications
18.
Asian J Surg ; 46(12): 5964-5965, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37704481
19.
Medicina (Kaunas) ; 59(8)2023 Aug 01.
Article in English | MEDLINE | ID: mdl-37629697

ABSTRACT

Pancreatic heterotopy is a rare entity defined as the presence of abnormally located pancreatic tissue without any anatomical or vascular connection to the normal pancreas. Heterotopic pancreatic tissue can be found in various regions of the digestive system, such as the stomach, duodenum, and upper jejunum, with the less commonly reported location being the gallbladder. Gallbladder pancreatic heterotopia can be either an incidental finding or diagnosed in association with cholecystitis. Pancreatitis of the ectopic tissue has also been described. In this context, we report three cases of heterotopic pancreatic tissue in the gallbladder with different types of pancreatic tissue according to the Heinrich classification. One patient was a 24-year-old male who presented with acute pancreatitis symptoms and an ultrasonographical detected mass in the gallbladder, which proved to be heterotopic pancreatic tissue. The other two cases were female patients aged 24 and 32, respectively, incidentally diagnosed on histopathological examination after cholecystectomy for symptomatic cholelithiasis. Both cases displayed chronic cholecystitis lesions; one of them was also associated with low grade dysplasia of the gallbladder. Although a rare occurrence in general, pancreatic heterotopia should be acknowledged as a possible incidental finding in asymptomatic patients as well as a cause for acute cholecystitis or pancreatitis.


Subject(s)
Cholecystitis , Choristoma , Pancreatitis , Male , Humans , Female , Young Adult , Adult , Acute Disease , Pancreatitis/diagnostic imaging , Pancreatitis/surgery , Cholecystitis/diagnostic imaging , Cholecystitis/surgery , Choristoma/diagnostic imaging , Choristoma/surgery , Diagnostic Imaging
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