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1.

A complex mosaic with tdic(13;18) (p11;p11), +13p-, +18p-, r(13) etc. in a male infant. II. Increased dissociation of dicentric chromosome by mitomycin C.

Uehara, M; Kida, M.

Jinrui Idengaku Zasshi ; 31(1): 37-43, 1986 Mar.

Article in English | MEDLINE | ID: mdl-3090320

Subject(s)

Abnormalities, Multiple/genetics , Chromosome Aberrations/genetics , Chromosomes, Human, 13-15/ultrastructure , Chromosomes, Human, 16-18/ultrastructure , Mosaicism , Bromodeoxyuridine/pharmacology , Cells, Cultured , Centromere/ultrastructure , Chromosome Disorders , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Ethidium/pharmacology , Female , Humans , Lymphocytes/ultrastructure , Male , Mitomycin , Mitomycins/pharmacology , Translocation, Genetic , Trisomy

2.

Effect of imipramine on human chromosomes studied by the method of poly-L-lysine binding.

Marfey, S P; Li, M G.

Z Naturforsch C Biosci ; 29C(9-10): 649-50, 1974.

Article in English | MEDLINE | ID: mdl-4278071

Subject(s)

Chromosomes/drug effects , Imipramine/pharmacology , Lysine/metabolism , Macromolecular Substances/metabolism , Protein Binding , Binding Sites , Cells, Cultured/metabolism , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Chromosomes, Human, 6-12 and X/drug effects , Humans , In Vitro Techniques , Isotope Labeling , Karyotyping , Lymphocytes/metabolism , Surface Properties , Time Factors , Tritium

3.

Inter- and intrachromosomal distribution of achromatic lesions and chromatid breaks in human chromosomes.

Obe, G; Lüers, H.

Mutat Res ; 16(3): 337-9, 1972 Nov.

Article in English | MEDLINE | ID: mdl-5078139

Subject(s)

Chromatids/drug effects , Chromosome Aberrations/drug effects , Isoniazid/pharmacology , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Chromosomes, Human, 6-12 and X/drug effects , Humans , Sex Chromosomes/drug effects

4.

The distribution and localization of drug-induced secondary constrictions in human chromosomes.

Brown, J A; Palmer, C G; Yu, P L.

Can J Genet Cytol ; 14(1): 81-93, 1972 Mar.

Article in English | MEDLINE | ID: mdl-5032114

Subject(s)

Bromodeoxyuridine/pharmacology , Chromosomes/drug effects , Hydroxylamines/pharmacology , Mitomycins/pharmacology , Analysis of Variance , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Chromosomes, Human, 6-12 and X/drug effects , Constriction , Female , Humans , Leukocytes/cytology , Leukocytes/drug effects , Male , Methods , Sex Chromosomes/drug effects , Time Factors

5.

In vitro alteration of association patterns of human acrocentric chromosomes.

Hoehn, H; Nagel, M; Krone, W.

Humangenetik ; 11(2): 146-54, 1971.

Article in English | MEDLINE | ID: mdl-4100467

Subject(s)

Cell Nucleolus/metabolism , Chromosomes/drug effects , Dactinomycin/pharmacology , Cell Division , Cell Nucleolus/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Culture Media , Humans

6.

5-bromodeoxyuridine-induced constrictions in human chromosomes.

Palmer, C G.

Can J Genet Cytol ; 12(4): 816-30, 1970 Dec.

Article in English | MEDLINE | ID: mdl-5512560

Subject(s)

Bromodeoxyuridine/pharmacology , Chromosomes/drug effects , Autoradiography , Chromosome Aberrations , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Culture Techniques , Female , Humans , Leukocytes , Male , Sex Chromosome Aberrations , Sex Chromosomes/drug effects , Trisomy

7.

[Inter- and intrachromosomal distribution of cyclophosphamid-induced chromosome aberrations in man]. / Inter- und intrachromosomale Verteilung von cyclophosphamid-induzierten Chromosomendefekten beim Menschen.

Schmid, E; Bauchinger, M.

Mutat Res ; 9(4): 417-24, 1970 Apr.

Article in German | MEDLINE | ID: mdl-5481038

Subject(s)

Chromosome Aberrations/drug effects , Cyclophosphamide/pharmacology , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Chromosomes, Human, 6-12 and X/drug effects , Cyclophosphamide/therapeutic use , Female , Humans , Neoplasms/drug therapy , Sex Chromosomes/drug effects

8.

Labeling and other effects of actinomycin D on human chromosomes.

Miles, C P.

Proc Natl Acad Sci U S A ; 65(3): 585-92, 1970 Mar.

Article in English | MEDLINE | ID: mdl-5267140

ABSTRACT

(3)H-actinomycin D, a guanine-binding agent, labels fixed human chromosomes nonrandomly. Actinomycin D added in G2 inhibits secondary constrictions and breaks chromosomes. There is some tendency for label to be concentrated at the ends of chromosomes and near the centromere. Labeling with (3)H-thymidine in the late stage of DNA synthesis shows a different pattern and in general lacks the telomeric concentrations. The sites of actinomycin D-induced breaks do not show good correspondence with the sites of actinomycin D label.

Subject(s)

Chromosomes/drug effects , Dactinomycin/pharmacology , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Chromosomes, Human, 6-12 and X/drug effects , DNA Replication , Fibroblasts , Humans , Lymphocytes , Sex Chromosomes/drug effects , Thymidine , Tritium

9.

[Inter- and intrachromosomal distribution of chromatid translocations in human leukocytes after in vitro treatment with trenimon]. / Inter- und intrachromosomale Verteilung von Chromatidtranslokationen nach Einwirkung von Trenimon auf menschliche Leukocyten in vitro.

Gebhart, E; Bauer, D.

Chromosoma ; 32(2): 152-61, 1970.

Article in German | MEDLINE | ID: mdl-5534924

Subject(s)

Chromatids/drug effects , Chromosome Aberrations/drug effects , Triaziquone/pharmacology , Animals , Chick Embryo , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Chromosomes, Human, 6-12 and X/drug effects , Humans , In Vitro Techniques , Leukocytes/drug effects , Sex Chromosomes/drug effects

10.

[Interchromosomal distribution of chemically induced achromatic lesions and chromatid breaks on human leukocyte chromosomes in vitro]. / Interchromosomale Verteilung chemisch induzierter achromatischer Läsionen und Chromatidbrüche auf menschlichen Leukozytenchromosomen in vitro.

Obe, G.

Z Naturforsch B ; 24(5): 655-6, 1969 May.

Article in German | MEDLINE | ID: mdl-4389805

Subject(s)

Chromosome Aberrations , Leukocytes/cytology , Mutagens/pharmacology , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 21-22 and Y/drug effects , Chromosomes, Human, 4-5/drug effects , Chromosomes, Human, 6-12 and X/drug effects , Humans , Leukocytes/drug effects , Quinones/pharmacology

11.

[The effects of thioguanine, hydroxylamine and 5-bromodeoxyuridine on human chromosomes in vitro]. / Die wirkung von Thioguanin, Hydroxylamin und 5-Bromodesoxyuridin auf menschliche Chromosomen in vitro.

Engel, W; Krone, W; Wolf, U.

Mutat Res ; 4(3): 353-68, 1967.

Article in German | MEDLINE | ID: mdl-4228103

Subject(s)

Bromodeoxyuridine/pharmacology , Chromosome Aberrations/drug effects , Chromosomes/drug effects , Hydroxylamines/pharmacology , Thioguanine/pharmacology , Chromosomes, Human, 1-3/drug effects , Chromosomes, Human, 13-15/drug effects , Chromosomes, Human, 16-18/drug effects , Chromosomes, Human, 19-20/drug effects , Chromosomes, Human, 4-5/drug effects , Floxuridine/pharmacology , Humans , In Vitro Techniques

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