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Gig Sanit ; (1): 67-70, 2009.
Article in Russian | MEDLINE | ID: mdl-19358360

ABSTRACT

The partial summation of biological effects evaluated by the anaphasic chromosomal aberration test in the bone marrow karyocytes of mice was determined when the animals were concurrently exposed to chemical substances (acetone, acetaldehyde, ammonia, and ethanol) at low concentrations and gamma-irradiation in a total dose of 30 Gy. Qualitative analysis of chromosomal aberrations in the karyocytes of the bone marrow (ponses, fragments) has indicated that upon combined exposure of the animals to the chemical substances and gamma-irradiation, the chemical factor is dominant since upon combined radiochemical exposure, the number of chromosomal aberration increases mainly at the expense of fragments (91.2%), as does upon isolated exposure to chemical substances (96.4%).


Subject(s)
Bone Marrow Cells/pathology , Chromosome Aberrations/chemically induced , Chromosome Aberrations/radiation effects , Chromosomes, Mammalian/drug effects , Chromosomes, Mammalian/diagnostic imaging , Gamma Rays/adverse effects , Radiation Injuries, Experimental/pathology , Animals , Bone Marrow Cells/drug effects , Bone Marrow Cells/radiation effects , Disease Models, Animal , Male , Mice , Mice, Inbred C57BL , Mice, Inbred CBA , Radiography
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