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2.
Lloydia ; 41(5): 432-4, 1978.
Article in English | MEDLINE | ID: mdl-713707

ABSTRACT

The stem bark and stem wood of Cinchona pubescens were found to owe their weak cytotoxic activity to the presence of quinovic acid. This acid and its 3-rhamnoside were isolated and characterized through several derivatives, all of which were assayed for their cytotoxicity.


Subject(s)
Antineoplastic Agents, Phytogenic/isolation & purification , Cinchona/analysis , Plants, Medicinal , Antineoplastic Agents, Phytogenic/therapeutic use , Neoplasms, Experimental/drug therapy , Phytotherapy
8.
J Chromatogr ; 104(2): 417-24, 1975 Feb 12.
Article in English | MEDLINE | ID: mdl-1150768

ABSTRACT

Alkaloids are separated by liquid chromatography on resins having functional carboxyl groups combined with copper (II) ions. The eluent is aqueous alcohol containing ammonia. Some resins retain alkaloids much better than others. Alkaloids studied included morphine, codeine, strychnine, atropine, papaverine, narcotine, cocaine, quinine, cinchonine and methadone.


Subject(s)
Alkaloids/analysis , Chromatography, Ion Exchange/methods , Atropine/analysis , Cinchona/analogs & derivatives , Cinchona/analysis , Cinchona Alkaloids , Cocaine/analysis , Codeine/analysis , Copper , Hydrolysis , Ion Exchange Resins , Methadone/analysis , Methods , Morphine/analysis , Noscapine/analysis , Papaverine/analysis , Plants, Medicinal , Quinine/analysis , Strychnine/analysis
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