ABSTRACT
Cardiac computed tomography (CT) is a special subset of CT, a subject about which much has been written in terms of the underlying concepts and mathematics and the sociologic impact. Cardiac CT has passed through three, chronologically overlapping, developmental stages and is now in its fourth stage of development. The first stage was fluoroscopy-based CT (1972-1995) stimulated by physiologic research needs, and the next was clinical CT-based exploration (1975-1980) of the potential of clinical CT in cardiology. This was followed by the electron beam CT-based stage (1980-present), which was the first CT approach applicable to clinical cardiology. Finally, volume-scanning CT imaging methods achieved with multislice scanning approaches of helical CT and by flat panel-based CT (1990-present), show great promise for clinically applicable CT of the cardiovascular system.
Subject(s)
Heart/diagnostic imaging , Tomography, X-Ray Computed/history , Animals , Cineangiography/history , Fluoroscopy/history , Heart Diseases/diagnostic imaging , Heart Diseases/history , History, 20th Century , Humans , Image Processing, Computer-Assisted/history , Tomography, X-Ray Computed/trendsSubject(s)
Coronary Angiography/history , Cineangiography/history , History, 20th Century , Humans , Mexico , United StatesABSTRACT
In recent years, the utility of radionuclide cineangiography in prognostication has made it a mainstay of management decision making. With evolution of therapeutic modalities and concomitant alteration in management strategies, however, the technique and its application are undergoing parallel evolution to optimize response to current needs. Thus, in addition to standard planar rest and exercise assessment of left ventricular function, newer approaches are involving combined perfusion and function assessment, application of pharmacological stress to permit technically advantageous variations in imaging protocols, and application of SPECT technology in collecting blood pool data for tomographic display and analysis.
Subject(s)
Cineangiography , Coronary Disease/diagnostic imaging , Acute Disease , Chronic Disease , Cineangiography/history , Exercise Test , History, 20th Century , Humans , Radionuclide ImagingABSTRACT
It has been 25 years since my colleagues and I were first approached to apply the then newly emerging technique of coronary arteriography to the study of the effects of the new vasodilator isosorbide dinitrate (ISDN) on coronary arteries in vivo. Through a combination of careful patient assessment and serendipity, we were able to visualize the prompt release of coronary artery spasm by ISDN. Ensuing years have seen dramatic advances both in angiographic techniques and in the knowledge of ISDN efficacy. This review will briefly summarize the early work with ISDN and detail how the improvements in cineangiography have fostered better understanding of the actions of ISDN.
