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1.
Allergol. immunopatol ; 44(6): 580-593, nov.-dic. 2016. graf, tab
Article in English | IBECS | ID: ibc-157881

ABSTRACT

Currently, mankind is afflicted with diversified health issues, allergies being a common, yet little understood malady. Allergies, the outcome of a baffled immune system encompasses myriad allergens and causes an array of health consequences, ranging from transient to recurrent and mild to fatal. Indoor allergy is a serious hypersensitivity in genetically-predisposed people, triggered by ingestion, inhalation or mere contact of allergens, of which mite and cockroaches are one of the most-represented constituents. Arduous to eliminate, these aeroallergens pose constant health challenges, mostly manifested as respiratory and dermatological inflammations, leading to further aggravations if unrestrained. Recent times have seen an unprecedented endeavour to understand the conformation of these allergens, their immune manipulative ploys and other underlying causes of pathogenesis, most importantly therapies. Yet a large section of vulnerable people is ignorant of these innocuous-looking immune irritants, prevailing around them, and continues to suffer. This review aims to expedite this field by a concise, informative account of seminal findings in the past few years, with particular emphasis on leading frontiers like genome-wide association studies (GWAS), epitope mapping, metabolomics etc. Drawbacks linked to current approaches and solutions to overcome them have been proposed


No disponible


Subject(s)
Humans , Pyroglyphidae/pathogenicity , Respiratory Hypersensitivity/epidemiology , Cockroaches/pathogenicity , Serine Proteases/immunology , Epitope Mapping , Metabolomics/methods , Genome-Wide Association Study/methods
2.
Rev. Asoc. Méd. Argent ; 127(4): 22-31, Dic.2014. ilus, graf
Article in Spanish | LILACS | ID: lil-767309

ABSTRACT

Se exponen los datos sobre la antigenicidad de las proteasas de la cucaracha Periplaneta americana y de la vinchuca Triatoma infestans en seres humanos residentes en la CABA y Gran Buenos Aires, así como en las provincias del Norte y Noreste del país. La antigenicidad cruzada entre ambas las convierte en 2 insectos de gran importancia en el ecosistema, y sus restos momificados de estadios adultos y ninfales de trascendencia para diversas patologías infecciosas y respiratorias...


Data concerning the cross-reactivity between the serinproteases of the cockroach Periplaneta Americana and the reduviid Triatoma infestans are exposed. Humans living in Buenos Aires as well as those living in the north of the country inhale mummified particles containing the powerful antigens of both insects and develop chronic respiratory illnesses...


Subject(s)
Humans , Cockroaches/pathogenicity , Respiratory Tract Diseases/etiology , Triatominae/pathogenicity , Argentina , Communicable Diseases/etiology
4.
Commun Agric Appl Biol Sci ; 73(3): 421-8, 2008.
Article in English | MEDLINE | ID: mdl-19226781

ABSTRACT

The Western corn rootworm (WCR) Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae) is a vexing alien invasive insect pest. It occupies the attention of entomologists in most countries of Europe and beyond. In spite of numerous research advances (e.g., Diabrotica symposium at Engelberg, Switzerland 2004) its behavior is still incompletely understood and cannot be predicted for a specific growing season with any degree of certainty. Nonetheless, by comparing several years in sequence a somewhat consistent and coherent picture is emerging that is subject of this contribution. The Ticino province received first beetles from the major infestation in Lombardy in 2000 across the geographically open border at Chiasso. The rapid advance of WCR in northerly direction along the river valleys of Ticino and Misox posed a threat to cantons north of the mountain chain of the Alps and beyond, a scenario outlined by Bertossa (2004), Wudtke et al. (2005) and subsequent papers. Following the Swiss Federal rule of crop rotation obligation around infested regions introduced in 2001, the rapid increase in population density leveled off. Careful monitoring by both Metcalf type pheromone and kairomone baited sticky traps and Hungarian traps provided a reliable tool for judging the success of any quarantine measures taken up until 2007. (1) Trends in population development of 2006 were confirmed. (2) However, for reasons not well understood, the overall population encountered in 2007 was significantly smaller in Ticino and neighboring areas of Lombardy, Italy, but also in other areas south of the Alps. This may be a consequence of the rather mild winter 2006-2007. (3) At the mountain pass of Monte Ceneri (some 600 m above sea level) no beetles were trapped in 2007, while 3 WCR were seen in 2006. (4) No new WCR were encountered in Swiss cantons north of the main chain of the Alps. (5) Metcalf sticky traps proved to be 4-5 times as sensitive as Hungarian traps used for comparison. By and large, mandatory crop rotation was beneficial in reducing WCR populations in Ticino and avoided or delayed northbound spread of WCR.


Subject(s)
Cockroaches/pathogenicity , Zea mays/growth & development , Zea mays/parasitology , Animals , Climate , Cockroaches/drug effects , Geography , Pheromones/pharmacology , Population Density , Population Dynamics , Switzerland
5.
Immunol Allergy Clin North Am ; 23(3): 483-99, 2003 Aug.
Article in English | MEDLINE | ID: mdl-14524387

ABSTRACT

The ubiquitous existence of cockroaches and the large-scale domestic infestation seen in inner cities make cockroach proteins a significant indoor allergen and a risk factor for asthma among inner-city residents. Studies have shown that early exposure to high levels of allergen may lead to the development of asthma in individuals with a genetic predisposition to asthma. Although field trials at cockroach abatement do not yield promising results, integrated pest management still remains the best control strategy. In highly susceptible or symptomatic patients, allergen-specific immunotherapy may be beneficial, although data are limited. As molecular techniques improve and recombinant allergens are developed, a more novel form of T-cell-specific immunotherapy may prove to be efficacious without the anaphylactic side effects seen with traditional allergy vaccines.


Subject(s)
Asthma/etiology , Cockroaches/immunology , Hypersensitivity/etiology , Allergens/adverse effects , Allergens/immunology , Animals , Classification , Cockroaches/classification , Cockroaches/pathogenicity , Disease Transmission, Infectious , Food Contamination , Humans , Hypersensitivity/immunology , Hypersensitivity/therapy , Immunotherapy , Insect Control , Public Health , T-Lymphocytes/immunology
7.
In. Llop Hern�ndez, Alina. Microbiolog�a y parasitolog�a m�dica. Tomo.III. La Habana, Ecimed, 2001. , ilus.
Monography in Spanish | CUMED | ID: cum-56330
8.
East Afr Med J ; 77(11): 622-6, 2000 Nov.
Article in English | MEDLINE | ID: mdl-12862110

ABSTRACT

BACKGROUND: Cockroach allergy occurs frequently in asthmatics in urban areas, where the level of cockroach infestation is usually high. The prevalence of cockroach allergy, as well as the effect of associated factors on cockroach sensitisation in Nigeria is largely unknown. OBJECTIVE: To determine the prevalence of cockroach allergy in asthmatics in Lagos. DESIGN: A prospective case-control study. SETTING: Medical outpatient department of the Lagos University Teaching Hospital, Lagos, Nigeria. SUBJECTS: Two hundred and two patients with confirmed bronchial asthma and one hundred non-asthmatic control subjects took part in the study. INTERVENTION: The cockroach allergen was administered on all the subjects using skin prick technique. MAIN OUTCOME MEASURES: The provocation of a skin reaction (wcal) fifteen minutes after administering the cockroach antigen. RESULTS: Amongst the asthmatic patients 90 (44.6%) had positive skin tests to the cockroach allergen, compared to nine (9%) of the control subjects. There was a male preponderance of cockroach sensitivity amongst the asthmatic patients even though the difference between both sexes was not significant. Other highlights of the study included the fact that cockroach sensitivity was related to age, duration of asthma, nocturnal asthmatic attacks, frequency of attacks, and the levels of infestation. There was an insignificant relationship between cockroach sensitivity and the location of residences as well as the income status of the respondents. CONCLUSION: There is the need for more studies on cockroach allergy in asthmatics in our environment.


Subject(s)
Asthma/complications , Asthma/epidemiology , Cockroaches/pathogenicity , Hypersensitivity/epidemiology , Hypersensitivity/etiology , Adolescent , Adult , Animals , Case-Control Studies , Female , Humans , Male , Middle Aged , Nigeria/epidemiology , Prevalence , Prospective Studies , Risk Factors , Urban Population/statistics & numerical data
9.
Rev. bras. alergia imunopatol ; 22(5): 151-5, set.-out. 1999. tab
Article in Portuguese | LILACS | ID: lil-279199

ABSTRACT

Objetivos: Verificar a freqüência de sensibilizaçäo àbaratas em crianças atópicas e relacioná-la à gravidade da asma. Método e Material: Testes cutâneos de leitura imediata por puntura com extrato misto (Greer Lab, USA) de Periplaneta americana (Pa) e Blatella germanica (Bg). Casuística e Resultados: A positividade ao teste cutâneo com extrato misto de baratas em 303 asmáticos atópicos atendidos em clínica particular foi de 24,1 por cento. A freqüência de reaçöes positivas foi significativamente maior na asma grave ( 40,7 por cento) do que nas formas leves ( 19,7 por cento). Conclusäo: A sensibilizaçäo às baratas é comum em asmáticos e relacionada às formas graves da doença. Fatores raciais e pobreza podem näo ser relevantes à sensibilizaçäo em nosso meio.


Subject(s)
Humans , Child , Asthma/drug therapy , Cockroaches/pathogenicity , In Vitro Techniques , Periplaneta , Skin Tests/adverse effects
10.
BRASÍLIA; FUNDAÇÃO HOSPITALAR DO DISTRITO FEDERAL; 1997. 1v p.
Non-conventional in Portuguese | LILACS | ID: lil-773657
11.
BRASÍLIA; FUNDAÇÃO HOSPITALAR DO DISTRITO FEDERAL; 1997. 1v p.
Non-conventional in Portuguese | LILACS, Coleciona SUS | ID: biblio-942063
12.
Arch. argent. alerg. inmunol. clín ; 27(2): 68-71, 1996. ilus
Article in Spanish | BINACIS | ID: bin-22574

ABSTRACT

Objetivo: Establecer la frecuencia de pruebas cutáneas positivas a cucaracha en un grupo de niños con asma bronquial alérgico residentes en la ciudad de Río Cuarto, Córdoba. Material y métodos: Se estudiaron 40 niños asmáticos tomados al azar -26 varones y 14 mujeres- con edades comprendidas entre 5,3 y 12,4 años (edad media, 8,2 años). Todos eran asistidos en el servicio de Alergia del Hospital San Antonio; provenían de zonas urbanas y suburbanas, y de clase socioeconómica media-baja. El diagnóstico de asma se basó en la historia clínica, niveles de IgE sérica total y signos de obstrucción respiratoria baja. Se consignó si en sus viviendas había desag³es cloacales. Se efectuaron pruebas cutáneas en la espalda mediante la técnica de Prick empleando, en dilución 1:10 p/v, extractos antígenos glicerinados de mezcla de cuerpo entero de Blatella germanica, Blatta orientalis y Periplaneta americana; ácaros, hongos anemófilos, pólenes, otros inhalantes y alimentos. La reacción fue leída a los 15 minutos y se consideró positiva cuando el diámetro de la pápula era ò 3mm. Resultados: La sensibilidad cutánea a por lo menos uno de los alérgenos probados fue positiva en el 90 por ciento de los casos. Para la cucaracha fue del 45 por ciento. No se observó sensibilidad exclusiva a dicho antígeno. No hubo relación con los niveles de IgE sérica total. La cucaracha fue positiva en el 50 por ciento de los niños de hogares que carecían de desag³es cloacales, y en el 33 por ciento de los casos que contaban con ese servicio. Conclusiones: La frecuencia de sensibilidad cutánea a alérgenos de cucaracha estaría condicionada, entre otros factores, por la carencia de servicio cloacal domiciliario. Esta carencia incrementaría el grado de infestación por cucaracha del ambiente donde el niño desarrolla sus actividades aumentando, en consecuencia, el riesgo de sensibilización (AU)


Subject(s)
Humans , Male , Female , Child, Preschool , Cockroaches/pathogenicity , Skin Tests/statistics & numerical data , Asthma/immunology , Asthma/etiology , Cockroaches/immunology , Excreta Disposal/standards , Sanitation/standards , Blatta americana/adverse effects , Blatta orientalis/adverse effects , Argentina
15.
Arch. argent. alerg. inmunol. clín ; 27(2): 68-71, 1996. ilus
Article in Spanish | LILACS | ID: lil-166479

ABSTRACT

Objetivo: Establecer la frecuencia de pruebas cutáneas positivas a cucaracha en un grupo de niños con asma bronquial alérgico residentes en la ciudad de Río Cuarto, Córdoba. Material y métodos: Se estudiaron 40 niños asmáticos tomados al azar -26 varones y 14 mujeres- con edades comprendidas entre 5,3 y 12,4 años (edad media, 8,2 años). Todos eran asistidos en el servicio de Alergia del Hospital San Antonio; provenían de zonas urbanas y suburbanas, y de clase socioeconómica media-baja. El diagnóstico de asma se basó en la historia clínica, niveles de IgE sérica total y signos de obstrucción respiratoria baja. Se consignó si en sus viviendas había desagües cloacales. Se efectuaron pruebas cutáneas en la espalda mediante la técnica de Prick empleando, en dilución 1:10 p/v, extractos antígenos glicerinados de mezcla de cuerpo entero de Blatella germanica, Blatta orientalis y Periplaneta americana; ácaros, hongos anemófilos, pólenes, otros inhalantes y alimentos. La reacción fue leída a los 15 minutos y se consideró positiva cuando el diámetro de la pápula era ò 3mm. Resultados: La sensibilidad cutánea a por lo menos uno de los alérgenos probados fue positiva en el 90 por ciento de los casos. Para la cucaracha fue del 45 por ciento. No se observó sensibilidad exclusiva a dicho antígeno. No hubo relación con los niveles de IgE sérica total. La cucaracha fue positiva en el 50 por ciento de los niños de hogares que carecían de desagües cloacales, y en el 33 por ciento de los casos que contaban con ese servicio. Conclusiones: La frecuencia de sensibilidad cutánea a alérgenos de cucaracha estaría condicionada, entre otros factores, por la carencia de servicio cloacal domiciliario. Esta carencia incrementaría el grado de infestación por cucaracha del ambiente donde el niño desarrolla sus actividades aumentando, en consecuencia, el riesgo de sensibilización


Subject(s)
Humans , Male , Female , Child, Preschool , Asthma/immunology , Cockroaches/pathogenicity , Skin Tests/statistics & numerical data , Argentina , Asthma/etiology , Blatta americana/adverse effects , Blatta orientalis/adverse effects , Cockroaches/immunology , Excreta Disposal/standards , Sanitation/standards
18.
La Plata; s.n; s.f. 1 p. (111795).
Non-conventional in Spanish | BINACIS | ID: bin-111795

ABSTRACT

Descripción de la alimentación, hábitos, y forma de reproducción de estos insectos, peligrosos transmisores de cólera, tuberculosis, y parasitosis, entre otras enfermedades. Se detallan brevemente algunas medidas de prevención e higiene domésticas


Subject(s)
Cockroaches/microbiology , Cockroaches/parasitology , Cockroaches/pathogenicity , Cockroaches/virology , Environmental Health Education
19.
La Plata; s.n; s.f. 1 p.
Non-conventional in Spanish | BINACIS | ID: biblio-1215530

ABSTRACT

Descripción de la alimentación, hábitos, y forma de reproducción de estos insectos, peligrosos transmisores de cólera, tuberculosis, y parasitosis, entre otras enfermedades. Se detallan brevemente algunas medidas de prevención e higiene domésticas


Subject(s)
Cockroaches/microbiology , Cockroaches/parasitology , Cockroaches/pathogenicity , Cockroaches/virology , Environmental Health Education
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